Clinical trials: Case-Control Studies
Aplastic Anemia
Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia
To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially the comprehensive multiple factors risks. The author conducted a case-control research included 338 AA cases and 1464 controls.
- Trial name
- MCSAA (NCT03208647)
- Testing
- AA or not
- Volunteers
- 1,802 people, healthy volunteers welcome
- Sponsor
- Shengyun Lin
Neoplasms, Cancer
PRediction Of Five Usual Tumors Using Blood Test for Risk Assessment and Early Detection
Liquid biopsy technology based on cell-free nucleic acids and protein characteristics has unique advantages and significant application prospects in cancer early detection.
- Trial name
- PROFUTURE (NCT05874648)
- Testing
- Multi-cancer early detection test
- Where
- China
- Volunteers
- 3,830 people, healthy volunteers welcome
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Primary Headache Disorders, Tension Headache
Pericranial and General Sensitivity in Patients With Primary Headache
Primary headaches such as migraine and tension type headache are among the most common neurological disorders and frequently cause significant disability and reduced quality of life.
- Conditions
- Primary Headache Disorders, Tension Headache, Tension-type Headache, Migraine
- Trial name
- HEAD-TMD (NCT07514208)
- Testing
- Pericranial Tenderness Assessment, Pressure Pain Threshold Assessment, Temporomandibular Disorder Assessment
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Transfusion-Related Acute Lung Injury, ARDS, Human
Comparison of the Proteome in ICU Patients in Search for TRALI Biomarkers: A Case-control Study Using Both Retrospective and Prospective Samples
Transfusion-related acute lung injury (TRALI) is a severe complication of blood transfusions. After a transfusion, TRALI develops in 0.08-15% of cases depending on the characteristics of the studied population.
- Trial name
- CURIE (NCT06444750)
- Testing
- Blood sample collection
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Chronic Instability of Joint
The Influence of Dual Task and Gait Speed on Gait Variability in Patients With Chronic Ankle Instability
Case-control study to evaluate gait parameters during different conditions between patients who suffer from chronic ankle instability and healthy individuals.
- Trial name
- NCT02745834
- Testing
- Gait analysis
- Where
- Israel
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Medical Corps, Israel Defense Force
Bleeding Disorder
Bleeding of Unknown Cause: a Swiss Case-control Study
The goal of this prospective cohort is to identified specific biological patterns in patients with a bleeding of unknown cause and to study the specific mechanisms of the bleeding disorder for each subset of patients.
- Trial name
- SWISS-BUC (NCT05713734)
- Testing
- Thrombin generation, Fibrinolysis, Fibrin clot structure
- Where
- 7 sites in Switzerland
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Carpal Tunnel Syndrome
Case-control Study on Individual Risk Factors of CTS
This study is conducted to observe the characteristics of the risk factors of CTS in Chinese population.
- Trial name
- NCT03166033
- Testing
- the disease
- Where
- China
- Volunteers
- 6,048 people, healthy volunteers welcome
- Sponsor
- Fudan University
Panic Disorder
IL-33, sST2, and CRP in Panic Disorder
Panic disorder (PD) is characterized by recurrent and unexpected panic attacks and is associated with significant functional impairment. Increasing evidence suggests involvement of immune-inflammatory mechanisms in PD.
- Trial name
- NCT07444879
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Elazığ Mental Health and Diseases Hospital
Hypospadias
Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in Picardie
We want to see if there is a relationship between exposure to pesticides and the occurrence of hypospade in Picard newborn .
- Trial name
- HYPOMECO (NCT02805491)
- Testing
- meconium, self questionnaires to parents
- Where
- 11 sites in France
- Volunteers
- 197 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Fractures, Bone, Bone Marrow Disease
Bone Marrow Adiposity and Fragility Fractures in Postmenopausal Women
The purpose is to determine in a case-control study if an association exist between bone marrow adiposity and fragility fractures in post-menopausal women.
- Conditions
- Fractures, Bone, Bone Marrow Disease, Fat Disorder, Adiposity
- Trial name
- ADIMOS (NCT03219125)
- Testing
- Dixon Magnetic Resonance Imaging, dual-energy X-ray absorptiometry (DXA)
- Where
- France
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Vestibulo-Ocular Reflex, Esports Participation
Comparison of Vestibulo-Ocular Reflex and Cognitive Functions in E-Athletes and Non-Athletes
This study aims to compare cognitive functions and functional vestibulo-ocular reflex (VOR) between e-athletes and non-athletes.
- Conditions
- Vestibulo-Ocular Reflex, Esports Participation, Cognitive Functioning
- Trial name
- NCT07211191
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Idiopathic Adolescent Scoliosis
Altered Hemorology in Adolescent Idıopathic Scoliosis
This study aims to investigate potential alterations in hemorheological parameters in adolescents with idiopathic scoliosis (AIS) compared to healthy controls.
- Trial name
- AHIAIS (NCT07102862)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Breast Cancer
Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software
The study objective is to assess the performance of the MammoDetector Pro to correctly mark biopsy-proven breast cancers imaged on the Siemens Mammomat Novation FFDM system compared to conventional film-screen mammography.
- Trial name
- NCT00756834
- Testing
- Screening
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions
HIV Infections
Effects on the Immune System of Anti-HIV Drugs in Patients Recently Infected With HIV
The purpose of this study is to find out whether these powerful combinations of anti-HIV drugs are safe and effective for use in patients in the early stages of HIV infection and to find out how patients' immune systems react to…
- Trial name
- NCT00001119
- Testing
- Tetanus Toxoid Vaccine, Indinavir sulfate, Lamivudine/Zidovudine
- Where
- 12 sites in United States, Australia
- Volunteers
- 288 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Psoriasis, Cardiovascular Diseases
Serum Lipid Levels and Other Biomarkers of Cardiovascular Disease in Patients With Psoriasis
Psoriasis patients are known to be at increased risk for heart disease. This may be due to the increased prevalence of cardiovascular disease risk factors in this population, including high blood pressure, diabetes, obesity, and…
- Conditions
- Psoriasis, Cardiovascular Diseases, Dyslipidemia
- Trial name
- NCT01019200
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- George Washington University
Chronic Periodontitis
Identification of EMT Indicators in Healthy and Periodontally Diseased Gingival Samples
The current study focuses on the localization and quantitative assessment of growth factors and cytokines related to the EMT process found in the human gingival tissue samples taken from periodontally diseased individuals…
- Trial name
- NCT03462953
- Testing
- Gingival tissue samples will be harvested
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cairo University
Sensitivity, Peri-implant Mucositis
Sensitivity and Specificity of Peri-Implantitis-Related Parameters
Bleeding on probing demonstrated to have high specificity with certain level of sensitivity to detect periodontal disease. Again, understanding the weak hemidesmosome attachment to the implant surface is imperative to discern on…
- Conditions
- Sensitivity, Peri-implant Mucositis, Peri-Implantational Loss, Peri-Implantitis
- Trial name
- NCT03031392
- Testing
- Sensitivity test
- Where
- Spain
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Center of Implantology, Oral and Maxillofacial Surgery, Badajoz, Spain
COPD
Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
Chronic obstructive pulmonary disease (COPD) is a common inflammatory disease of the airway affecting approximately 10% of individuals aged 40 years or more with a smoking history.
- Trial name
- NCT01780298
- Where
- United Kingdom
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
Breast Cancer
Case-Control-Study on the Breast Cancer Risk of Mirena® Compared With Copper IUDs
The objective of this study is to determine the breast cancer risk of Mirena® users compared to copper intrauterine device (IUD) users in a community-based case-control study.
- Trial name
- NCT00461253
- Testing
- Levonorgestrel-releasing IUD, Copper IUD
- Where
- Germany
- Volunteers
- 25,565 people, healthy volunteers welcome
- Sponsor
- Center for Epidemiology and Health Research, Germany
Vitamin D Deficiency, Periodontitis
25-Hydroxyvitamin D Levels in Patients With Periodontitis (Stage III)
Periodontitis; is an inflammatory disease of tissues characterized by bone destruction around the teeth. Vitamin D plays an important role in several inflammatory diseases by promoting the expression of inflammatory cytokines…
- Trial name
- NCT05343273
- Testing
- taking a blood sample
- Where
- Turkey (Türkiye)
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ataturk University