Clinical trials: Case Management
Keratoconus
Evaluation of Safety and Efficacy of a Bioengineered Corneal Implant for Treatment of Keratoconus
This is a prospective, Phase I open-label safety study to evaluate the safety, feasibility and initial efficacy of a bioengineered corneal stromal substitute after implantation into the stroma of adults with advanced keratoconus.
- Trial name
- LinkCor (NCT04653922)
- Testing
- LinkCor Bioengineered Corneal Implant
- Where
- 2 sites in India, Iran
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- LinkoCare Life Sciences AB
Postpartum Hemorrhage, Nursing Education
The Effect of Using Virtual Simulation on Students' Knowledge and Skill Levels Regarding Postpartum Hemorrhage Management
The purpose of this study is to find out whether virtual simulation helps nursing students learn how to manage postpartum hemorrhage (heavy bleeding after childbirth).
- Conditions
- Postpartum Hemorrhage, Nursing Education, Virtual Simulation
- Trial name
- NCT07912021
- Testing
- Virtual Simulation, Case Study
- Where
- Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Uludag University
Parkinson's Disease (At-risk Cases)
MOVIN' CARE for PD (Risk Management)
The goal of this intervention study is to investigate the effectiveness of three preventive interventions - yoga, arts-based approaches, and somatic practices, with reference to an active control group - traditional exercises, in…
- Trial name
- jcpdmcP (NCT06147284)
- Testing
- Preventive interventions
- Where
- Hong Kong
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Implant Assesment
Bio-implant Root Analogue Versus Conventional Screw-type Implant for Management of Pier Abutment in Mandibular Distal Extension Cases
reviewing literature was lacking for bio implant and management of pier abutment in distal extension bases for this reason the aim of this research will be to use the bio implant in the management of pier abutment cases for…
- Trial name
- NCT07284680
- Testing
- Implant
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malaria
Community-led Responses for Elimination: Controlled Trial of Reactive Case Detection Versus Reactive Drug Administration
This study is designed to compare the effectiveness of reactive focal drug administration (RFDA) using dihydroartemisinin+piperaquine (DHAP) versus reactive focal test and treat (RFTAT) using artemether+lumefantrine (AL) as a…
- Trial name
- CORE Zambia (NCT02654912)
- Testing
- Reactive Focal Drug Administration
- Where
- Zambia
- Volunteers
- 8,682 people, healthy volunteers welcome
- Sponsor
- PATH
Diarrhoea, Pneumonia
HCU: Can VHVs Trained in ICCM Improve Care for Children
This study will assess how the current VHV (VHV=CHW, community health worker) scope can be expanded to include iCCM and if such group interventions can provide improved access to treatment for children.
- Conditions
- Diarrhoea, Pneumonia, Malaria
- Trial name
- HCU:VHV/ICCM (NCT02072629)
- Testing
- Training of VHVs in iCCM
- Volunteers
- 4,071 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Long-term and Permanent Contraceptive Methods
A Prospective Observational Study of the Clinical Performance of Zarin in Madagascar
This one-year observational study will monitor the contraceptive effectiveness, safety and acceptability of Zarin during the first year of use after the method has been approved for public use in Madagascar.
- Trial name
- NCT01200576
- Where
- Madagascar
- Volunteers
- 621 people, healthy volunteers welcome
- Sponsor
- FHI 360
Hepatitis C
Link Hepatitis C Notifications to Treatment in Tasmania
This project will utilise the notification process as a point of intervention to work with primary practitioners (GP) by contacting them directly when a notification of hepatitis C exposure is received by the Tasmanian department…
- Trial name
- NCT04510246
- Testing
- Enhanced case management
- Where
- Australia
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
HIV/AIDS
PlusCare: Mobile Platform to Increase Linkage to Care in Adolescents Living With HIV/AIDS
While major advancements in medical technology over the past decade have significantly improved the life expectancy of persons infected with human immunodeficiency virus (HIV), HIV-positive youth today face new barriers to the…
- Trial name
- NCT03758066
- Testing
- PlusCare
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Dimagi Inc.
Caregiver Burnout
The Effect on Caregivers of a Family Support Program
The purpose of this study is to investigate the effect of a family support program based on the nurse-led case management model on individuals providing care for patients who are confined to bed at home.
- Trial name
- NCT05542472
- Testing
- Family Support Program Based on a Nurse-Led Case Management Model
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Asthma
HFS in the Assessement and Management of Severe Asthma Attack Among Fifth Year Medical School Students
Bedside clinical case learning, such for respiratory distress, represent a challenge for medical teachers, especially in critical conditions.
- Trial name
- SimAG (NCT02776358)
- Testing
- High Fidelity Simulation, Video case
- Where
- Tunisia
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- University of Monastir
Abdominal Aortic Aneurysm, Endovascular Procedures
Standardization of Physician-Modified Stent Grafts for Abdominal Aortic Aneurysms
This study explores the use of physician-modified stent grafts (PMSGs) for treating abdominal aortic aneurysms that are unsuitable for open surgery or standard endovascular grafts.
- Conditions
- Abdominal Aortic Aneurysm, Endovascular Procedures, Stents, Vascular Surgical Procedures
- Trial name
- RESTORE (NCT06585215)
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Aplastic Anemia
Multi Center Case Control Study on Multiple Risk Factors of Aplastic Anemia
To ascertain the risk factors of AA in ZheJiang Province of China at the moment, especially the comprehensive multiple factors risks. The author conducted a case-control research included 338 AA cases and 1464 controls.
- Trial name
- MCSAA (NCT03208647)
- Testing
- AA or not
- Volunteers
- 1,802 people, healthy volunteers welcome
- Sponsor
- Shengyun Lin
Different Treatment Outcomes of Atrophied Distal Extension Cases
Clinical and Radiographic Evaluation of Three Different Modalities for Management of Distal Extension Atrophied Mandibular Ridge: A One Year Prospective Study
Nine patients selected for this study with mandibular free end saddle and atrophied posterior ridge according to treatment options all patients will be divided randomly into 3 groups: Group A: included three participants who will…
- Trial name
- NCT05978115
- Testing
- implant supported prosthesis
- Where
- Egypt
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Oral Cancer, Psychological Distress
Develop and Evaluate An Artificial Intelligence Assisted Prehabilitation Program for Returning to Work and Cost-effectiveness Analysis in Patients With Oral Cancer
The goal of this clinical trial is to develop and evaluate an Artificial Intelligence Assisted Prehabilitation Program (AI APP) for returning to work and cost-effectiveness analysis in patients with oral cancer (OC).
- Conditions
- Oral Cancer, Psychological Distress, Communication Aids for Disabled, Physiotherapy
- Trial name
- NCT07562100
- Testing
- Prehabilitation application, Conventional physiotherapy, Scar management
- Where
- 5 sites in Taiwan
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance)
Multimodal Risk Factor Graph Mapping, Metabolic Subtyping, and Digital Intelligent Chronic Disease Management for Prediabetes: An Integrated Cohort and Case-Control Clinical Study
This observational study aims to understand the metabolic characteristics and long-term changes in adults with prediabetes and to identify risk and protective factors associated with progression to diabetes or return to normal…
- Conditions
- Prediabetes, Prediabetes (Insulin Resistance, Impaired Glucose Tolerance), Impaired Fasting Glucose, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- DM-PIONEER (NCT07854002)
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Patient Satisfaction
Polyetherketoneketone and Metal Framework for Management of Maxillectomy Cases: Across Over Study
Prosthetic rehabilitation of acquired maxillary defects represents a challenging mission for both the prosthodontist and psychologically traumatized patients.
- Trial name
- NCT06070727
- Testing
- Obturator
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Cardiovascular Disease
Feasibility and Usability of a Pedometer in a Cardiovascular Disease Prevention Program for French-speaking Canadians
The purpose of this prospective randomized controlled trial (RCT) is to evaluate the feasibility and usability of a commercial pedometer and web application in a case-managed home-based Cardiovascular disease prevention and…
- Trial name
- PiezoRx (NCT02837471)
- Testing
- PiezoRx medical grade pedometer
- Where
- 2 sites in Canada
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Caregiver Burnout, Case Management
Caregiver Support Model & Psycho-Education Program On Empowerment: Development and Validation
This Project aims to provide social workers and relevant human service professionals with a comprehensive, scientific, and validated service model and suggest a sustainable support framework on the working process of helping and…
- Conditions
- Caregiver Burnout, Case Management, Empowerment
- Trial name
- NCT04272918
- Testing
- Caregiver Support Model, Psycho-education Program
- Where
- Hong Kong
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- City University of Hong Kong