Clinical trials: Carotid Artery Stenoses
Carotid Stenosis
Effect on Cerebral Oxygenation by Sevoflurane or Propofol Using Near-infrared Spectroscopy in Carotid Endarterectomy
The aim of this study is comparing the effect on cerebral oxygenation by sevoflurane-remifentanil or propofol-remifentanil anesthesia in patient undergoing carotid endarterectomy.
- Trial name
- NCT02609087
- Testing
- Sevoflurane, Propofol
- Where
- South Korea
- Volunteers
- 69 people
- Sponsor
- Chonnam National University Hospital
Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients
Correlation Between Carotid Stump Pressure and Interhemispheric rSO₂ Asymmetry During Awake Carotid Endarterectomy
This study aims to better understand how well the brain is perfused (supplied with blood and oxygen) during a specific type of surgery called carotid endarterectomy (CEA), which is performed to prevent strokes in people with…
- Conditions
- Carotid Artery Stenosis Symptomatic, Carotid Endarterectomy (CEA) Surgical Patients, Cerebral Hypoperfusion
- Trial name
- NCT07150260
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Izmir Katip Celebi University
Extracranial Atherosclerosis
Images in Extracranial Artery Stenosis
The goals of this trial are: 1. To compare the sensitivity and specificity of various tools including Doppler and magnetic resonance imaging (MRI) for diagnosing vertebral artery stenosis and carotid artery stenosis.
- Trial name
- NCT00173927
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Artery Stenosis
Transcranial Doppler for Internal Carotid Artery Stenting (TCD-ICAS)
Carotid artery stenting (CAS) prevents stroke but carries risks of perioperative cerebral embolism. Transcranial Doppler (TCD) ultrasound can detect microemboli during CAS and may offer therapeutic benefits through…
- Trial name
- NCT07462546
- Testing
- Transcranial Doppler
- Where
- China
- Volunteers
- 232 people
- Sponsor
- General Hospital of Shenyang Military Region
Cardiovascular Diseases, Carotid Stenosis
Recurrent Carotid Stenosis
To determine whether recurrent stenosis following carotid endarterectomy could be reduced by pre- and post-operative oral administration of platelet-inhibiting drugs.
- Conditions
- Cardiovascular Diseases, Carotid Stenosis, Cerebrovascular Disorders, Heart Diseases
- Trial name
- NCT00000527
- Testing
- aspirin, dipyridamole
- Sponsor
- Emory University
Cognitive Function, Stenosis
Clinical Registration Study of Patients With Intracranial / Carotid Stenosis
Through prospective registration and follow-up, this study will collect data of patients with intracranial/carotid stenosis, including clinical information, neuropsychological scales, multimodal magnetic resonance images.
- Trial name
- NCT05322824
- Testing
- standard medical treatment, Interventional stenting
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypoxic Preconditioning, Carotid Artery Stenosis
Hypoxic Preconditioning on Patients
The purpose of this study is to study the effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis.
- Conditions
- Hypoxic Preconditioning, Carotid Artery Stenosis, Ischemic Cerebrovascular Disease
- Trial name
- NCT02966418
- Testing
- Mild Hypoxia Preconditioning
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Hua Yan
Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction
Clinical Impact of Using IMPROVE to Select Patients for Carotid Revascularisation
Narrowing of the carotid artery due to atherosclerosis with an unstable plaque can cause a stroke. Patients with carotid artery disease who have had a TIA or minor stroke and are at high risk of another stroke are often treated…
- Conditions
- Carotid Artery Stenosis Symptomatic, Ischemic Cerebral Infarction, Stroke Ischemic, Atheroscleroses
- Trial name
- IMPROVE (NCT07556887)
- Testing
- IMPROVE Risk Model
- Where
- 10 sites in Netherlands
- Volunteers
- 613 people
- Sponsor
- Maastricht University Medical Center
Carotid Artery Plaque
Photoacoustic Imaging of Atherosclerotic Plaques
Stroke is a major cause of death and disability worldwide. Stenotic carotid arteries can lead to stroke if the cause of the stenosis is a vulnerable atherosclerotic plaque.
- Trial name
- NCT04237064
- Testing
- Photoacoustic imaging
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Marc van Sambeek
Carotid Artery Stenosis
Effect of Carotid Artery Stent on Evoked Cerebral Blood Oxygenation and Neurocognitive Functioning
Cerebral hemodynamic compromise from internal carotid artery stenosis may be a cause of vascular cognitive impairment that is amenable to treatment by revascularization.
- Trial name
- NCT04651998
- Testing
- MMSE, MoCA, functional near-infrared spectroscopy
- Where
- China
- Volunteers
- 74 people
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Carotid Stenosis, Postoperative Cognitive Dysfunction
Neurocognitive Function After Carotid Thrombendarterectomy
Previous studies did not reach a consensus on the influence of the type of anesthesiologic procedure and monitoring, during carotid thrombendarterectomy, on perioperative complications and cognitive outcomes.
- Conditions
- Carotid Stenosis, Postoperative Cognitive Dysfunction, Neurological Impairment
- Trial name
- NCT05739357
- Testing
- NIRS, EEG
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- Clinical Hospital Centre Zagreb
Stroke, Stenosis
Abciximab for Prevention of Stroke Recurrence Before Endarterectomy in Symptomatic Carotid Stenosis
The purpose of the present prospective, randomized, double-blind, double dummy controlled multicenter pilot study is to investigate whether abciximab, compared with aspirin, is able to reduce the rate of recurrent ischemic…
- Trial name
- NCT00126139
- Testing
- Abciximab
- Where
- 5 sites in Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Ischemic Stroke, Transient Ischemic Attack
Comparison Between Non-contrast Magnetic Resonance Angiography and Carotid Doppler in Cerebrovascular Stroke
This prospective observational study aims to compare the diagnostic performance of non-contrast magnetic resonance angiography (NC-MRA) and carotid Doppler ultrasonography in the evaluation of carotid artery disease among…
- Conditions
- Ischemic Stroke, Transient Ischemic Attack, Carotid Artery Stenosis (Symptomatic and Asymptomatic)
- Trial name
- NCT07756775
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Sohag University
Carotid Artery Stenosis
The Effects of Dexmedetomidine and Remifentanil on Carotid Patients
We propose to test whether intraoperative administration of dexmedetomidine will reduce hemodynamic control in the intra- and post-operative periods and reduces PACU analgesic requirements in patients undergoing carotid…
- Trial name
- NCT00335972
- Testing
- Remifentanil, Dexmedetomidine
- Where
- United States
- Volunteers
- 142 people
- Sponsor
- The Cleveland Clinic
Carotid Artery Stenosis
Optimization Strategy of Carotid Artery Stenosis
The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy.
- Trial name
- COAS-CAS (NCT05629000)
- Testing
- Carotid revascularization, MRI-PWI, CTA
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Carotid Artery Stenosis
Troponin In Carotid Revascularization
Patients undergoing carotid revascularization procedures are at increased risk for the development of short- and long-term cardiac complications.
- Trial name
- TROPICAR (NCT05293067)
- Testing
- high-sensitive troponin
- Where
- Serbia
- Volunteers
- 527 people
- Sponsor
- University of Belgrade
Patients With Any Degree of Carotid Artery Stenosis and Vulnerable Features in the Carotid Artery Plaque
Prospective Carotid Artery Stenosis Trial
Researchers are collecting information and blood from subjects undergoing carotid artery interventions.
- Trial name
- NCT05724836
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Mayo Clinic
Carotid Artery Stenosis, Carotid Atherosclerosis
New Ischemic Cerebral Lesions After Endarterectomy vs. Stenting for the Treatment of Symptomatic Carotid Stenosis
Background and purpose. Even if periprocedural cerebral microembolism associated with carotid endarterectomy or stenting usually does not manifest as clinically overt stroke, neuropsychological disturbances resulting from these…
- Conditions
- Carotid Artery Stenosis, Carotid Atherosclerosis, Stroke, Ischemic
- Trial name
- CARECarotid (NCT03764306)
- Testing
- Carotid Artery Stenting, Endarterectomy carotid artery
- Volunteers
- 31 people
- Sponsor
- Jagiellonian University
Brain Tumor, Stroke, Acute
Safety and Feasibility of the Infinity Catheter for Radial Access
The main objective of this single arm study is to evaluate the safety and feasibility of the AXS Infinity LS (Stryker, Freemont, CA, USA) and AXS Infinity LS Plus (Stryker, Freemont, CA, USA) catheters during the transradial…
- Conditions
- Brain Tumor, Stroke, Acute, Brain Aneurysm, Intracranial Arteriovenous Malformations
- Trial name
- NCT04553549
- Testing
- Transradial approach
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Carotid Artery Stenosis
Improved Image Quality for Assessment of Carotid Artery Stenosis by Ultrafast Ultrasound FLOW Imaging
Objective: To evaluate the technical performance of a novel cascaded wave imaging technique compared to plane wave imaging for blood flow imaging in patients with and without carotid artery stenosis.
- Trial name
- CAS-iFLOW (NCT06170580)
- Testing
- Conventional duplex, Ultrasound-based flow imaging using plane wave imaging, Ultrasound-based flow imaging using cascaded wave imaging
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center