Clinical trials: Carotid Artery Disease
Non-diabetic Chronic Kidney Disease, Atherosclerosis
Serum Omentin-1 and Carotid Atherosclerosis In Non-Diabetic Chronic Kidney Disease
The aim of the study is to evaluate whether a low level of serum omentin-1 is associated with carotid atherosclerosis and mediated by inflammation.
- Trial name
- NCT01701830
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Kocaeli Derince Education and Research Hospital
Cardiovascular Diseases, Heart Diseases
Epidemiology of Carotid Disease in Elderly Adults
To determine whether a population with isolated systolic hypertension (ISH) had a higher prevalence of carotid disease than a normotensive population matched for age and sex, and to determine specific risk factors for carotid…
- Conditions
- Cardiovascular Diseases, Heart Diseases, Hypertension, Carotid Artery Diseases
- Trial name
- NCT00005230
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Internal Carotid Artery Stenosis
Ultrasound-guided Intermediate Cervical Plexus Block
The investigators test with the present study design, whether an ultrasound-guided blockade of the cervical plexus in combination with an additional application of local anesthetic to the superficial cervical ansa (facial nerve…
- Trial name
- NCT02794974
- Testing
- cervical plexus block, facial nerve block, perivascular block
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- Helios Research Center
Carotid Artery Stenosis, Aortic Calcification
Aortic Calcification - is it a Marker for Carotid Artery Stenosis?
Atherosclerosis is the major contributor for the morbidity and mortality for the variety of cardiovascular diseases. Aortic calcification on x-ray is a marker for arterial atherosclerosis and an independent prognostic factor for…
- Trial name
- NCT01458860
- Volunteers
- 200 people
- Sponsor
- Ziv Hospital
Stroke, Atheroscleroses
A Cohort Study on Cardiovascular and Cerebrovascular Outcomes
A standardized tool for grading carotid atherosclerotic plaques-dubbed Carotid Plaque-RADS (Reporting and Data System)-has recently been developed.
- Trial name
- NCT07178015
- Testing
- ultrasound scanning
- Where
- China
- Volunteers
- 855 people
- Sponsor
- Sun Yat-sen University
Moyamoya Disease
Treatment of Moyamoya Disease With iPSC-derived Exosomes
Moyamoya disease is a cerebrovascular disease clinically characterized by chronic progressive stenosis or occlusion at the ends of bilateral internal carotid arteries and the origin of anterior cerebral arteries and middle…
- Trial name
- NCT07065409
- Testing
- iPSC-EVs
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Huaqiu Zhang
Atherosclerosis
A Study to Evaluate the Effects of 3 Months Dosing With GW856553, as Assessed FDG-PET/CT Imaging
This study is being conducted to assess the potential anti-inflammatory effects of a 3-month treatment with GW856553, on the inflammatory activity within the aorta and carotid plaques, as assessed by FDG-PET/CT.
- Trial name
- NCT00633022
- Testing
- LOSMAPIMOD 7.5 MG
- Where
- 4 sites in United Kingdom
- Volunteers
- 99 people
- Sponsor
- GlaxoSmithKline
Carotid Artery Diseases
The CREST-2 Registry
The objective of C2R is to promote the rapid initiation and completion of enrollment in the CREST-2 randomized clinical trial (clinicaltrials.gov ID NCT02089217).
- Trial name
- C2R (NCT02240862)
- Testing
- Carotid Artery Stent
- Where
- United States
- Volunteers
- 8,000 people
- Sponsor
- University of Maryland, Baltimore
Chest Pain, Acute Coronary Syndrome
The FOVUS-ER Study: Focused Vascular Ultrasound to Risk Stratify Patients With Chest Pain in the ER
Broad Goal: To demonstrate that focused vascular ultrasound (FOVUS) can accurately risk stratify patients with chest pain in the emergency department (ED).
- Conditions
- Chest Pain, Acute Coronary Syndrome, Carotid Artery Plaque
- Trial name
- FOVUS-ER (NCT02947360)
- Testing
- Focused vascular ultrasound of the carotid arteries
- Where
- Canada
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- Queen's University
Diabetes Mellitus, Type 2, Vascular Diseases
Rosiglitazone Plaque Study
The purpose of this study is to determine whether rosiglitazone, a peroxisome proliferator activated receptor gamma (PPAR-gamma) agonist, induces regression in carotid atherosclerotic plaques in diabetic patients with vascular…
- Conditions
- Diabetes Mellitus, Type 2, Vascular Diseases, Hypertension
- Trial name
- NCT00123227
- Testing
- Rosiglitazone
- Where
- 2 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Carotid Artery Stenosis
Neuropsychological Functioning and Cerebral Perfusion Post Carotid Endarterectomy
The study aims to investigate the relationship between neuropsychological functioning and brain perfusion in patients undergoing carotid endarterectomy and control patients undergoing other peripheral vascular procedures.
- Trial name
- NCT04759859
- Where
- United States
- Sponsor
- CAMC Health System
Asymptomatic Carotid Stenosis, Symptomatic Carotid Stenosis
Transcranial Doppler(TCD) Evaluation of High Intensity Transient Signals and Carotid Disease
Carotid Disease causes 10% of strokes. The Investigators are attempting to investigate the use of Transcranial Doppler to see if this is and effective, efficient, and/or valid way to identify individuals at highest risk for…
- Conditions
- Asymptomatic Carotid Stenosis, Symptomatic Carotid Stenosis, TCD, HITS
- Trial name
- TCD (NCT05829200)
- Testing
- Transcranial Doppler (TCD)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Ochsner Health System
Atherosclerosis, Coronary Arteriosclerosis
Genetic- and Biological-Markers of Predisposition to Atherosclerosis: Leipzig-Heart Study
Atherosclerotic cardiovascular disease is the major cause of morbidity and mortality in Western societies. It is a complex genetic disorder with many genes involved and significant gene-environment interactions.
- Conditions
- Atherosclerosis, Coronary Arteriosclerosis, Carotid Artery Diseases, Genetic Predisposition to Disease
- Trial name
- LE-Heart (NCT00497887)
- Where
- 2 sites in Germany
- Volunteers
- 4,000 people
- Sponsor
- University of Leipzig
Cognitive Function in Carotid Stenting
Assessment of Cognitive Function in Patients Undergoing Carotid Artery Stent Placement
To determine the effect of carotid artery stenting, on cognitive function, in patients with high grade carotid artery stenosis
- Trial name
- NCT00919165
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Corewell Health West
HIV Infections, HIV Seronegativity
Carotid Artery Thickness in HIV Infected and Uninfected Adults
The intima-media thickness (IMT) test is a low cost, non-invasive way to measure the thickness of the carotid artery (the large artery in the neck).
- Conditions
- HIV Infections, HIV Seronegativity, Atherosclerosis
- Trial name
- NCT00007319
- Where
- 10 sites in United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Carotid, Aortic, Renal or Peripheral Artery Disease
Crossover Comparison of Two Gadolinium Contrast Agents for Use With MRA of Carotid, Renal and Peripheral Arteries
To compare two gadolinium contrast agents in terms of global paired diagnostic preference (primary endpoint) for the assessment of contrast-enhanced MR Angiography of the carotid, renal/abdominal and peripheral arteries
- Trial name
- VALUE (NCT01260636)
- Testing
- Gadobenate Dimeglumine, Gadopentetate Dimeglumine
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Bracco Diagnostics, Inc
Mucopolysaccharidoses
Carotid Structure and Function in MPS Syndromes: A Multicenter Study of the Lysosomal Disease Network
Mucopolysaccharidosis (MPS) syndromes are disorders characterized by enzyme deficiencies, and they have been linked to heart health complications.
- Trial name
- NCT01586871
- Where
- 2 sites in United States
- Volunteers
- 1,147 people
- Sponsor
- University of Minnesota
Cardiovascular Diseases, Testicular Neoplasms
High-Intensity Aerobic Interval Training in Testicular Cancer Survivors
This study evaluates the impact of a supervised 12-week high-intensity aerobic interval exercise program (versus a self-directed exercise usual care group) on traditional and novel cardiovascular disease risk factors and…
- Trial name
- HIITTS (NCT02459132)
- Testing
- High-intensity aerobic interval exercise
- Volunteers
- 63 people
- Sponsor
- University of Alberta
Coronary Disease, Heart Diseases
VA HDL Intervention Trial (VA-HIT) Ancillary Study Data Analysis
To evaluate additional cardiovascular risk factors using data from the VA HDL Intervention Trial (VA-HIT).
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Carotid Artery Diseases
- Trial name
- NCT00035711
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Stroke (CVA) or TIA, Carotid Artery Plaque
[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease
This clinical trial aims to evaluate whether [¹⁸F]AlF-OC PET/MRI can characterize and quantify inflammation in carotid atherosclerotic plaques.
- Conditions
- Stroke (CVA) or TIA, Carotid Artery Plaque, Atherosclerosis Cardiovascular Disease, Carotid Arteriosclerosis
- Trial name
- NCT07104487
- Testing
- [18F]AlF-OC
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven