Clinical trials: Caries Root
Caries,Dental, Apical Periodontitis
Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine…
- Trial name
- NCT04105985
- Testing
- Kovanaze Nasal Spray, Articaine Injection
- Sponsor
- Virginia Commonwealth University
Caries Roots, Flouride Varnish
Effectiveness Silver Diamine Fluoride Versus Sodium Fluoride in Arresting Caries Around Crown Margins in Older Adults
Dental caries is a multifactorial, progressive disease which is the major causes of dental pain, infection and tooth loss. Dental caries can substantially compromise the quality of life in older adults 1 2.
- Conditions
- Caries Roots, Flouride Varnish, Caries; Dentin, Caries Arrested
- Trial name
- NCT04255251
- Testing
- Silver Diammine Fluoride, Fluoride Varnishes
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of New England
Dental Caries, Pulp Necrosis
Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars
This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric…
- Conditions
- Dental Caries, Pulp Necrosis, Primary Tooth Pulpectomy, Pediatric Dentistry
- Trial name
- MORvNAOCL (NCT06971055)
- Testing
- Sodium hypochlorite, Moringa Oleifera Leaf Extract
- Where
- Egypt
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Caries of Root Surface, Surgery
Intraoral Imaging at Clinical Crown Lengthening
Crown lengthening surgery is done when a tooth needs to be fixed with a crown. Sometimes, not enough of the tooth sticks out above the gum to support a crown.
- Trial name
- NCT03064217
- Testing
- Making impression at surgery
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Irreversible Pulpitis (Toothache), Dental Caries (Diagnosis)
Evaluation of the Success Rate of Pulpotomy Versus to Root Canal Therapy in Management of Mature First Permanent Molars With Irreversible Pulpitis
The goal of This current study compare the clinical \& radiographic success rate between two different modalities conventional RCT and VPT using Bio-C-Repair as a pulp capping material to treat young patients with mature first…
- Trial name
- NCT07046533
- Testing
- (pulpotomy), root canal treatment
- Volunteers
- 60 people
- Sponsor
- Lamiaa Saeed Ahmed Elshiekh
Hydration, Dental Caries
Healthy Hydration Pilot in Elementary Schools
This study will pilot a school-based stakeholder-informed hydration intervention and examine its feasibility and preliminary efficacy.
- Conditions
- Hydration, Dental Caries, Body Mass Index
- Trial name
- NCT06132763
- Testing
- Hydration Intervention, Control - Assessments Only
- Where
- United States
- Volunteers
- 563 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Root Caries
Prevention and Arrest of Root Caries Lesions with High Fluoride Concentration Mouthwash Versus Normal Fluoride Concentration Mouthwash in Elderly Patients
The study evaluats the effectiveness of regular fluoride 220 ppm F with erythritol and high fluoride 500 ppm F with erythritol mouthwashes against a placebo (regular fluoride 220 ppm F mouthwash) in the prevention of new root…
- Trial name
- NCT06723054
- Testing
- regular fluoride 220 ppm F mouthwash without erythritol, regular fluoride 220 ppm F mouthwash with erythritol, high fluoride 500 ppm F mouthwash with erythritol
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Murali Srinivasan, Dr. med. dent., BDS, MDS, MBA, MAS
Root Caries
Comparison of Silver Diamine Fluoride and Sodium Fluoride Varnish to Prevent and Arrest Root Caries in Older Adults
Dental caries (coronal and root) is highly prevalent in older adults. It is important to identify and implement the most effective methods that prevent the formation of root caries lesions and inhibit existing lesions at the…
- Trial name
- NCT04432415
- Testing
- Silver Diamine Fluoride, Soduim Fluoride Varnish
- Where
- Mexico
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Mexico
Carious Lesion, Cervical Caries
Clinical Performance of ARS Containing Universal Adhesives in Carious Cervical Lesions
Evaluation of composite restorations done in carious cervical lesions restored by a conventional universal adhesive in comparison to a universal adhesive that contains and resistant silane coupling agent according to the Modified…
- Trial name
- NCT06572124
- Testing
- universal adhesive without Acid resistant silane coupling agent, universal adhesive with Acid resistant silane coupling agent
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chronic Apical Periodontitis
Effect of Different Sealers and Activation Methods on Pain
In this study, the effects of different irrigation agitation methods and different root canal filling sealers on postoperative pain after root canal treatment will be evaluated.
- Trial name
- NCT06860191
- Testing
- Root Canal Sealants
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Root Caries
Non-invasive Treatment of Root Caries in Older Adults
This study aims to test the effectiveness in reducing or arresting root caries lesion in community-dwelling elderly subjects by using high fluoridated toothpaste.
- Trial name
- MIT-RCTalca (NCT02647203)
- Testing
- Self-administered fluoridated dentifrices
- Where
- Chile
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- University of Talca
Dental Caries of Root Surface, Root Caries
Root Caries Prevention Using Fluoride Varnish Fortified With SBGC
The goal of this 36-month double-blind randomized controlled trial is to compare the effects of 5% sodium fluoride varnish (22,600 ppm fluoride) with or without Strontium-doped bioactive glass (SBGC) on root caries development in…
- Trial name
- SBGC (NCT06131957)
- Testing
- Fluoride varnish with SBGC, Fluoride varnish
- Where
- Hong Kong
- Volunteers
- 540 people
- Sponsor
- The University of Hong Kong
Cervical Caries
Clinical Performance of Short Fiber Reinforced Resin Modified Glass Ionomer Restorations in Cervical Carious Teeth (1y Randomized Clinical Trial)
This research proposal is introduced to clinically test short fiber reinforced glass ionomer material from GC Europe due to gap of knowledge present in this area.
- Trial name
- NCT06185881
- Testing
- restoration of cervical carious teeth
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries, Vertical Root Fracture
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Mandibular Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of hemisection versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07633834
- Testing
- hemi sectioning
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Post-operative Pain, Pulpitis - Irreversible
Outcomes of Pulpotomy and Root Canal Treatment in Teeth With Symptomatic Irreversible Pulpitis
The aim of this study is to evaluate the clinical effectiveness of total pulpotomy (TP), radicular pulpotomy (RP), and root canal treatment (RCT) in mandibular premolar and/or molar teeth diagnosed with symptomatic irreversible…
- Conditions
- Post-operative Pain, Pulpitis - Irreversible, Success Rate
- Trial name
- NCT07375576
- Testing
- Total Pulpotomy, Radicular pulpotomy, Root canal treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Root Caries, NaF
The Efficacy of Tooth Mouse, SFD and NaF in Caries Activity in Root Caries. A Randomized Clinical Trial
The aim of this study is to summarize the current level of evidence on the prevalence of root caries in elderly population, evaluate the prevalence of root caries in elderly patients living in Canton Bern, Switzerland and to…
- Conditions
- Root Caries, NaF, SDF, Tooth Mousse
- Trial name
- NCT05765058
- Testing
- Group A, Group B, Group C
- Where
- Switzerland
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Bern
Root Caries
Assessment of Arresting Root Surface Caries After the Application of PRG Bioactive Varnish
Guidelines proved that arresting and remineralization of the root surface caries is better than weakening the tooth structure and restoring it.
- Trial name
- NCT05509920
- Testing
- S-PRG barrier coat
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Cairo University
Root Caries
Silver Diamine Fluoride Application on Root Caries Fillings
The goal of this clinical trial is to learn the influence of prior silver diamine fluoride (SDF) application on root caries fillings. The main questions to answer 1.
- Trial name
- NCT06514885
- Testing
- SDF solution application, Tonic water
- Where
- Hong Kong
- Volunteers
- 184 people
- Sponsor
- The University of Hong Kong
Cervical Caries
Clinical Performance of Bioceramic vs High Viscosity GIC for Cervical Restorations of Geriatric Patients
The aim of this study is to clinically evaluate the performance of the bioceramic glass ionomer compared to conventional high viscosity glass ionomer for restoration of carious cervical lesions in geriatric patients over 12…
- Trial name
- NCT05624008
- Testing
- Bioceramic glass ionomer restoration, Resin modified glass ionomer restoration
- Where
- Egypt
- Volunteers
- 28 people
- Sponsor
- Cairo University
Teeth; Lesion, Dental Root Caries
5-year Clinical Evaluation of Cavity Lining on the Restoration
The purpose of this double-blind, randomized trial is to compare the clinical performance of a composite restorations in root surface carious lesions with or without resin modified glass ionomer lining.
- Trial name
- NCT03802539
- Testing
- Glass Liner
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hacettepe University