Clinical trials: Cardiovascular Prevention
Childhood Obesity, Cardiovascular Disease Prevention
Family Matters Intervention
The proposed study is a 12-month, individual randomized controlled trial (RCT). The main aim of the study is to decrease cardiovascular disease risk (BMI percentile, neck circumference) and improve child diet quality in children…
- Trial name
- NCT02669797
- Testing
- In-home Visits and Food Preparation Activities, Ecological Momentary Intervention, Feedback on Video-recorded Family Meals
- Where
- 2 sites in United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Cardiovascular Diseases, Obesity Prevention
Mediterranean Diet Education in Shift Nurses: Effects on Sleep, Activity, and Health Parameters
This study aimed to evaluate the effects of Mediterranean diet education on sleep quality, physical activity levels, blood parameters, and anthropometric measurements among shift-working nurses.
- Conditions
- Cardiovascular Diseases, Obesity Prevention, Atheroscleroses, Hypertension
- Trial name
- NCT07123610
- Testing
- Mediterranean Diet Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Primary Prevention, Vascular Calcification
GUIDE-CAC: Statin-Ezetimibe Without Aspirin vs. Statin Monotherapy With Aspirin in High Coronary Calcification
A Multicenter, randomized trial comparing the efficacy and safety of intensive lipid-lowering therapy using a statin-ezetimibe combination without aspirin versus statin monotherapy with aspirin in asymptomatic patients with…
- Trial name
- NCT06722521
- Testing
- Pitavastatin 4mg and ezetimibe 10mg, taken once daily, Pitavastatin 2 mg with aspirin 100 mg, taken once daily.
- Where
- South Korea
- Volunteers
- 7,435 people
- Sponsor
- Asan Medical Center
Atrial Fibrillation, Arrhythmias, Cardiac
Wearable Cardiac Monitor to Enhance Detection of Arrhythmia Recurrence After Catheter Ablation of Atrial Fibrillation
The WEAR-AF study is a prospective, multicenter clinical trial designed to evaluate the efficacy of wearable technology in the detection, monitoring, and management of atrial fibrillation (AF).
- Conditions
- Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases
- Trial name
- WEAR-AF (NCT06564012)
- Volunteers
- 100 people
- Sponsor
- Sunnybrook Health Sciences Centre
Diabetes Mellitus, Cardiovascular Diseases (CVD)
Da Qing Offspring Study
This is an observational study tracking families and offspring of three cohorts from the 1986 Da Qing study: newly diagnosed diabetes, impaired glucose tolerance, and normoglycemia groups.
- Conditions
- Diabetes Mellitus, Cardiovascular Diseases (CVD), Offspring, Adult, Impaired Glucose Tolerance (Prediabetes)
- Trial name
- NCT06958640
- Testing
- Lifestyle interventions
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- China-Japan Friendship Hospital
Cardiovascular Diseases, Obesity Prevention
Team-based Learning Intervention to Prevent Risk Factors for Chronic Diseases - a Cluster Randomized Trial
Background: Chronic diseases, such as cardiovascular diseases, diabetes, and cancer, are a major global health issue. Their modifiable risk factors, including poor diet, physical inactivity, irregular sleep, tobacco use, and…
- Conditions
- Cardiovascular Diseases, Obesity Prevention, Sedentary Behaviors, Sleep Perception
- Trial name
- NCT06894134
- Testing
- Team-based learning
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Professor Fernando Figueira Integral Medicine Institute
Heart Disease, Chronic Disease
Real-World Evaluation of a Digitally Enabled Cardiac Rehabilitation Program
After a heart event or procedure, patients are encouraged to participate in a cardiac rehabilitation (CR) program to improve their health and reduce the risk of future problems.
- Conditions
- Heart Disease, Chronic Disease, Cardiovascular Disease Prevention
- Trial name
- NCT06813482
- Testing
- Digitally enabled cardiac rehabilitation, F2F-CR, Usual Care Group
- Where
- Australia
- Volunteers
- 172 people
- Sponsor
- Baker Heart and Diabetes Institute
Cardiovascular Prevention, Healthy
Connect2Move: Valorization of Natural Cardio Trekking Hiking Trails
Regular exercise improves performance and reduces the risk of cardiovascular disease. Endurance and strength training are therefore forms of therapy with a high level of evidence in the prevention and rehabilitation of…
- Conditions
- Cardiovascular Prevention, Healthy, Healthy Lifestyle
- Trial name
- Connect2Move (NCT05226806)
- Testing
- Measurement of cardiorespiratory performance in 3 different settings, GENERAL CARDIO HIKES AS PART OF GENERAL TOURIST OFFER OF MUNICIPALITIES
- Where
- Germany
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Statin, Cardiovascular Risk Factors
Role of Coronary CTA on Lipid Management and Risk Factors Control in an Asymptomatic Chinese Population
The primary objective of this study is to determine whether coronary computed tomography angiography (CCTA) -based coronary heart disease(CHD) prevention strategy improves lipid-lowering treatment and cardiovascular risk factor…
- Conditions
- Statin, Cardiovascular Risk Factors, Primary Prevention, Adherence, Medication
- Trial name
- RESPECT2 (NCT05725096)
- Testing
- Coronary Computed Tomography Angiography, Traditional cardiovascular risk stratification
- Where
- China
- Volunteers
- 3,400 people
- Sponsor
- Zhang longjiang,MD
Weight Maintenance, Weight Loss
ObeSity and Jobs in SoCioeconomically Disadvantaged CommUnities: A Randomized CLinical Precision Public HealTh Intervention --The SCULPT-Job Study
This is an interventional research study about clinical, psychosocial, and behavioral factors that impact weight loss, weight maintenance, and cardiovascular disease in socially disadvantaged persons.
- Conditions
- Weight Maintenance, Weight Loss, Stress, Psychological, Job Stress
- Trial name
- SCULPT-Job (NCT04709549)
- Testing
- Diabetes Prevention Program + Job and Legal Services, Diabetes Prevention Program
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of California, San Francisco
Cardiac Rehabilitation, Secondary Prevention
Effectiveness of the Aktivplan Digital Intervention (ACTIVE-CaRe Pilot)
The goal of this clinical pilot / feasibility study is to determine the feasibility of conducting a large-scale clinical effectiveness trial of the aktivplan digital intervention in cardiac rehabilitation patients.
- Conditions
- Cardiac Rehabilitation, Secondary Prevention, Cardiovascular Diseases
- Trial name
- NCT06025526
- Testing
- aktivplan, Usual care
- Where
- 2 sites in Austria
- Volunteers
- 34 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
Cardiovascular Diseases, Risk Reduction
Strategy for Cardiovascular Disease Prevention Through Tailored Health Management in Individuals With Elevated Risk
The China PEACE SMARTER trial is a cluster ramdomized trial aiming to assess the effectiveness of village doctor-led tailored health management on risk reduction of high-risk individuals for cardiovascular disease.
- Conditions
- Cardiovascular Diseases, Risk Reduction, Primary Prevention
- Trial name
- SMARTER (NCT05645640)
- Testing
- Village doctor-led tailored health management
- Where
- China
- Volunteers
- 4,533 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cardiovascular Prevention
The Cardiovascular Prevention Program
Cardiovascular diseases represent one of the main public health problems being the leading cause of morbidity, disability and mortality.
- Trial name
- NCT06362538
- Testing
- International Physical Activity Questionnaire, Six minute walking test, SF-36, Euro-Qol 5D-5L, Perceived stress scale-10, Pittsburgh Sleep Quality Index, Depression Anxiety Stress scale- 21.
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Maria Cecilia Hospital
Acute Coronary Syndrome, Prevention
Cholesterol Self-testing in Patients Post Acute Coronary Syndrome
The pharmacological reduction of LDL-C lowers cardiovascular risk and is therefore a priority in cardiovascular secondary prevention.
- Conditions
- Acute Coronary Syndrome, Prevention, LDL Hyperlipoproteinemia, Therapeutic Adherence
- Trial name
- C-Check (NCT06526013)
- Testing
- Cholesterol self-measurement
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University of Leipzig
Cardiovascular Diseases, Chronic Disease
Improving Therapeutic Adherence in Cardiovascular Secondary Prevention.
The goal of this open label randomized controlled trial is to evaluate the efficacy of an intervention through health education based on the Chronic Care Model's implementation to increase therapeutic adherence in patients with…
- Conditions
- Cardiovascular Diseases, Chronic Disease, Secondary Prevention, Coronary Disease
- Trial name
- AT-PSC (NCT06510946)
- Testing
- (Health education program) To increase therapeutic adherence in patients with secondary prevention for cardiovascular disease
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Preeclampsia Severe, Cardiovascular Diseases
Postpartum Low-Dose Aspirin After Preeclampsia for Optimization of Cardiovascular Risk (PAPVASC)
Women who develop preeclampsia (PE) in pregnancy are at a greater risk for adverse cardiovascular health outcomes. PE is associated with vascular remodeling and functional changes in the postpartum, reflective of its systemic…
- Conditions
- Preeclampsia Severe, Cardiovascular Diseases, Primary Prevention
- Trial name
- PAPVASC (NCT04243278)
- Testing
- Low-dose aspirin
- Where
- Canada
- Volunteers
- 14 people
- Sponsor
- Dr. Graeme Smith
Prevention of Subclinical Atherosclerosis Progression, Prevention of Cognitive Decline
Nattokinase Atherothrombotic Prevention Study
The potential for nattokinase to "thin" blood and to reduce blood clotting by positive antithrombotic and fibrinolytic effects presents a unique opportunity to safely study such effects on cardiovascular disease and cognition.
- Trial name
- NAPS (NCT02080520)
- Testing
- Nattokinase
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Hematocrit Change, Cardiovascular Prevention
Empagliflozin and Red Blood Cell 2,3-biphosphoglycerate Levels
The aim of this study is to investigate the hypothesis that treatment with empagliflozin may have an impact on red blood cell 2,3-biphosphoglycerate levels affecting tissue oxygen supply and thus mediating part of the cardio- and…
- Conditions
- Hematocrit Change, Cardiovascular Prevention, Empagliflozin, SGLT2-Inhibitors
- Trial name
- NCT06284850
- Testing
- Empagliflozin10Mg Tab
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
Cardiovascular Prevention, Screening
New Cardiovascular Risk Screening Strategy.
Mortality due to cardiovascular disease (CVD) in Spain accounted for 29% of all deaths (32% in women and 26% in men) in 2017. Out of those, 67% were related to a coronary or a cerebrovascular disease .
- Conditions
- Cardiovascular Prevention, Screening, Peripheral Artery Disease, Arteriosclerosis
- Trial name
- HELENA (NCT05884840)
- Testing
- HELENA
- Where
- Spain
- Volunteers
- 54,000 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cardiovascular Diseases, Cardiovascular Disease Prevention
Community Pharmacist Intervention to Enhance Adherence in Cardiovascular Drug Initiators
The goal of this clinical trial is to evaluate a community pharmacist intervention aimed at improving medication adherence in patients starting newly prescribed medication for cardiovascular disease prevention.
- Trial name
- PHARM-ADHERE (NCT06142838)
- Testing
- community pharmacist intervention
- Where
- Belgium
- Volunteers
- 1,600 people
- Sponsor
- University Ghent