Clinical trials: Cardiovascular Health Status
Hypothalamic Amenorrhea
Hypothalamic Amenorrhea as a Fertility Status Marker for Cardiovascular Health (ARCH)
Hypothalamic amenorrhea (HA) occurs during reproductive years and results in stopped menstrual cycles and infertility which can be prolonged from months to years and is characterized by varying combinations of psychosocial…
- Trial name
- ARCH (NCT05629377)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Mayo Clinic
Heart Failure
Randomized Implementation of Routine Patient-Reported Health Status Assessment Among Heart Failure Patients in Stanford Cardiology
This randomized quality improvement study evaluates the routine assessment of patient-reported heath status, using the Kansas City Cardiomyopathy Questionnaire-12 (KCCQ-12) among adult outpatients seen in heart failure clinic or…
- Trial name
- NCT05564572
- Testing
- Routine Health Status Assessment
- Where
- United States
- Volunteers
- 3,000 people
- Sponsor
- Stanford University
Stroke
The Effects of Vibration on Lower Limb Muscle Strength, Functional Status, and Psychological Health in Stroke Patients
The goal of this clinical trial is to the effect of vibration training on lower limb muscle strength, functional status and psychological health of stroke patients.
- Trial name
- NCT07333456
- Testing
- wearable vibration, vertical vibration, early rehabilitation
- Where
- Taiwan
- Volunteers
- 115 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Heart Failure
Dynamic Heart Failure Prediction With Real-time Functional Status Data in the Ambulatory Setting
Heart failure is the number one cause of hospital readmission in those over 65 years of age and the current standard-of-care of weight self-monitoring is inadequate to predict exacerbation.
- Trial name
- NCT03702062
- Testing
- 6 Minute Walk Test Smart phone Application
- Where
- United States
- Sponsor
- University of California, San Francisco
Heart Failure
Evaluating the Effectiveness of Sildenafil at Improving Health Outcomes and Exercise Ability in People With Diastolic Heart Failure (The RELAX Study)
Diastolic heart failure (DHF), which affects older individuals and women at a disproportionate rate, is a condition that can lead to shortness of breath and fluid build-up in the lungs.
- Trial name
- RELAX (NCT00763867)
- Testing
- Sildenafil
- Where
- 10 sites in United States, Canada
- Volunteers
- 216 people
- Sponsor
- Duke University
Cardiovascular Diseases
Comparing Multicomponent and Isometric Multicomponent Training: Impact on Fitness, Health, and Life Quality in Heart Patients
The goal of this clinical trial is to evaluate if a multicomponent training program (MCT), including aerobic and resistance exercises, or an isometric multicomponent training program (IMCT) can improve physiological, physical…
- Trial name
- NCT06819098
- Testing
- Multicomponent Training Protocol, Isometric Multicomponent Training
- Where
- Italy
- Volunteers
- 36 people
- Sponsor
- University of Bari Aldo Moro
Heart Failure, Pulmonary Disease, Chronic Obstructive
Telehome Monitoring for Chronic Disease Management
People living in rural areas are at increased risk for poor health outcomes due to: long distance to health care facilities, less available health care resources such as primary care and specialty services, transportation…
- Conditions
- Heart Failure, Pulmonary Disease, Chronic Obstructive, Hypertension, Diabetes Mellitus
- Trial name
- NCT02035566
- Testing
- Telehome Care Monitoring
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- University of Maryland, Baltimore
Coronary Artery Disease
Impact of Coronary Artery Stenting on Quantitative Myocardial Blood Flow and Health Status
We propose to perform PET MPI studies in patients before and after stenting to evaluate changes (or lack thereof) in MBFR and how that is associated with changes (or lack thereof) in symptoms, functional status and quality of…
- Trial name
- NCT04475094
- Testing
- Rubidium-82, Seattle Angina Questionnaire-7, Rose Dyspnea Scale
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Cardiovascular Imaging Technologies
Vitamin D Status
Effect of Different Vitamin D Vitamers on Vitamin D Status
Background: Dietary intake of vitamin D includes vitamin D3 (VitD3), 25-hydroxyvitamin D3 (25OHD3) and vitamin D2 (VitD2). However, the bioactivity of the different species is currently not scientifically established.
- Trial name
- VitD (NCT02860663)
- Testing
- Vitamin D3, Vitamin D2, 25OHD
- Where
- Denmark
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders
Effects of Shift Work on Nurse Staff Health
Shift work deeply impacts on temporal organization leading to a circadian desynchronization, which translates into a worsening of the sleep quality and work ability during waking hours.
- Conditions
- Shift Work Type Circadian Rhythm Sleep Disorder, Chronobiology Disorders, Mood Swing, Physical Activity
- Trial name
- Turnisti (NCT03453398)
- Testing
- Shifts working hours with different schedules
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio
Heart Failure, Heart Failure With Reduced Ejection Fraction (HFrEF)
The Effect of Vericiguat on Peripheral Vascular Function, Patient Health Status and Inflammation
The concept that direct stimulation of soluble guanylate cyclase (sGC) could be a particularly effective approach to increase cyclic guanosine monophosphate (cGMP) in conditions of increased inflammation/oxidative stress…
- Trial name
- NCT05420012
- Testing
- Vericiguat
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- Josef Stehlik
Suboptimal Health Status
Evaluation of Laser Acupuncture on Health Promotion of Sub-health People
Background: Suboptimal health status (SHS) is a dynamic state wherein people have not been diagnosed with a disease but tend to develop diseases. People with SHS often experience fatigue and other nonspecific symptoms.
- Trial name
- NCT04325945
- Testing
- Low level laser therapy
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Type 2 Diabetes, Hypertension
Evaluating the Effectiveness of a Multi-level Health-Related Social Needs Initiative
The goal of this study is to evaluate the effectiveness of a multi-level health-related social needs (HRSN) initiative among adult patients diagnosed with type 2 diabetes, plus hypertension or hyperlipidemia.
- Conditions
- Type 2 Diabetes, Hypertension, Hyperlipidemia, Health-related Social Problems
- Trial name
- NCT06831162
- Testing
- Multi-level HRSN initiative
- Where
- United States
- Volunteers
- 4,809 people
- Sponsor
- Vanderbilt University Medical Center
Aortic Valve Disease
Health Status of < 50 Year Old Patients After Surgically Implanted Biological and Mechanical Aortic Valves: a Population-based Retrospective Analysis (2010-2020)
The overall project aim is to study outcomes following aortic valve replacement with either mechanical valves or bioprostheses by retrieving data from the main social security carriers in Austria for the years 2010-2020 in under…
- Trial name
- NCT05627973
- Testing
- Aortic Valve Replacement
- Volunteers
- 991 people
- Sponsor
- Medical University of Vienna
Metabolism Disorder, Hypertension
High-Intensity Interval Training on Pre-Hypertensive Subjects
Despite exercise training decrease blood pressure in 'average' terms, there is a wide interindividual variability after exercise training, being yet unknown what mode of exercise (e.g.
- Trial name
- NCT03000140
- Testing
- High Intensity Interval Training, Control group
- Where
- Chile
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Universidad Santo Tomas
CVD - Cardiovascular Disease
Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation
This study is being done to evaluate whether a program called Heart to Heart, that helps patients make a more informed decision about cardiac rehab (CR), is interesting, acceptable to participants, and whether participants would…
- Trial name
- H2H (NCT06908590)
- Testing
- Education, Providing and Engaging Social Support and Assistance with Health System Navigation
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Health Literacy, Communication
Health Literacy and Cardiovascular Knowledge Workshop in Women From Disadvantaged Communities
The current health literacy (HL) pilot intervention was designed through focus groups with women in low socio-economic status (SES) communities. The primary HL issue identified was communication challenges at doctors' visits.
- Trial name
- NCT03203018
- Testing
- Interactive workshop based on community specific needs
- Where
- Israel
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Refractory Ischemia
Quality of Life in Patients With Refractory Angina
The health and well being of patients with refractory angina will be assessed using validated questionnaires (SF-36 and Seattle Angina Questionnaire [SAQ]) at baseline and one year.
- Trial name
- NCT00840437
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Minneapolis Heart Institute Foundation
Heart Failure, Congestive
Patient-Centered Heart Failure Trial
The purpose of this study is to evaluate a patient-centered disease management intervention for VA patients with heart failure.
- Trial name
- PCDM (NCT00461513)
- Testing
- Intervention
- Where
- 4 sites in United States
- Volunteers
- 384 people
- Sponsor
- VA Office of Research and Development
Stroke, Rehabilitation
Changes in and Determinants of Movement Performance, Functional Status, and Health-Related Quality of Life After Stroke Rehabilitation
A total of 144 stroke patients 6 -24 months post onset who are between 45 and 75 years old will be recruited. A randomized-blocks pretest and posttest control group design will be applied.
- Trial name
- NCT00780533
- Where
- Taiwan
- Volunteers
- 70 people
- Sponsor
- National Taiwan University Hospital