Clinical trials: Cardiovascular Health
Acute MI, Heart Failure
Cardiovascular Kidney and Metabolic Health Assessment and Patient Empowerment
The primary objective of CHAPERONE solution is to evaluate the efficacy of engaging, assessing, and enabling long term treatment strategy with Health Artificial Intelligence (AI) Chatbot, Copilot, Large Language Model (LLM) and…
- Conditions
- Acute MI, Heart Failure, Diabetes Mellitus, Kidney Disease
- Trial name
- CHAPERONE-CKM (NCT07403669)
- Testing
- CHAPERONE AI, CKMiq AI, Quality of Life
- Where
- 5 sites in United States, Sweden
- Volunteers
- 300 people
- Sponsor
- Aventyn, Inc.
Hyperlipidemias, Diabetes
Social Needs Screening and Chronic Diseases Study (WE CARE)
The goal of this clinical trial is to learn if the implementation of the WE CARE social determinants of health (SDOH) screening and referral intervention with an antiracist lens in primary care settings can lead to a meaningful…
- Conditions
- Hyperlipidemias, Diabetes, Depression, Pediatric Asthma
- Trial name
- NCT06903897
- Testing
- WE CARE SDOH System, Standard Pediatric Care
- Where
- 3 sites in United States
- Volunteers
- 68,000 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Heart Failure, Heart Failure Patients
Telematic Educational Intervention in Patients With Heart Failure.
Background: Heart Failure (HF) is one of the most prevalent pathologies in Western countries, representing a significant percentage of their healthcare expenditure.
- Trial name
- TEACH (NCT07317882)
- Testing
- Digital health
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Maria Jose Santi Cano
Physical Inactivity, Dyslipidemia
Implementation Facilitation of Exercise is Medicine Greenville
A public health priority exists for the U.S. healthcare sector to integrate physical activity (PA) as a part of the patient care model.
- Conditions
- Physical Inactivity, Dyslipidemia, Obesity and Overweight, Hypertension
- Trial name
- NCT07340580
- Testing
- Clinic Implementation Facilitation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Hypertension
COmpliance and Efficacy in Mono and Combination Tablet Study ATacand/Atacand Plus
To evaluate compliance and patients' satisfaction in mono and combination treatment of Candesartan cilexetil (Atacand)/ Candesartan cilexetil 16mg, hydrochlorothiazide 12.5mg (Atacand plus) in hypertension.
- Trial name
- COMBAT (NCT00526279)
- Where
- 3 sites in South Korea
- Volunteers
- 9,000 people
- Sponsor
- AstraZeneca
Deep Vein Thrombosis, Abdominal Aortic Aneurism
Point-of-care Ultrasound in Finland
This study has two aims. 1. Deep venous thrombosis (DVT) is a common suspected medical condition. If it cannot be excluded clinically and using D-dimer, ultrasound examination is required.
- Conditions
- Deep Vein Thrombosis, Abdominal Aortic Aneurism, Pneumothorax, Gallbladder Diseases
- Trial name
- NCT03327688
- Testing
- Point-of-care ultrasound
- Where
- 4 sites in Finland
- Volunteers
- 220 people
- Sponsor
- Ossi Hannula
Coronary Artery Disease
Impact of Health Literacy on Outcomes and Effectiveness of Shared Decision Making Programs in Patients With Chronic Diseases
Study objective was to explore the impact of health literacy on effectiveness of an educational intervention describing life-style and behavior modification for patients "Living with Coronary Artery Disease." Our hypothesis was…
- Trial name
- NCT01083862
- Testing
- Educational Intervention - Text plus DVD/VHS, Educational Intervention - Text Only
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- University of Cincinnati
Cardiovascular Diseases, Diabetes Mellitus, Type 2
Role of Fasted Exercise on Improving Cardiometabolic Health
The aim of this randomised control trial is to investigate the role of fasted exercise on cardiometabolic health. Participants will be assigned to one of three conditions, fasted exercise, fed exercise and control (no exercise).
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Type 2, Obesity
- Trial name
- NCT05742373
- Testing
- Exercise training in the fasted state, Exercise training in the fed state
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manchester Metropolitan University
Cardiovascular Diseases, Hypertension
The African-PREDICT Study
The African-PREDICT study aims to (i) generate new knowledge on the early pathophysiology accompanying hypertension development in black South Africans; and (ii) to identify early novel markers or predictors for the development…
- Conditions
- Cardiovascular Diseases, Hypertension, Health Risk Behaviors, Arterial Stiffness
- Trial name
- PREDICT (NCT03292094)
- Where
- South Africa
- Volunteers
- 1,202 people, healthy volunteers welcome
- Sponsor
- North-West University, South Africa
Medication Adherence, Stroke
Improving Medication Adherence Through SMS (Short Messaging Service) in Adult Stroke Patients: a Randomised Controlled Behaviour Intervention Trial
The impact of medications used for secondary stroke prevention relies heavily upon patient adherence. Adherence is defined as "the extent to which a person's behavior - taking medication, following a diet, and/or executing…
- Trial name
- NCT01986023
- Testing
- SMS- Short Messaging Service
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Aga Khan University
Cardiovascular Risk Score
10 Years Cardiovascular Risk Score Among Primary Health Care Centre Attendees, Assiut Governorate.
The study aim to assess cardiovascular risk score among patients of AlHadary primary health care centre in Waldeya, Assiut governorate. And to determine the awareness about cardiovascular risk among these patients as well.
- Trial name
- NCT05330962
- Testing
- Framingham study cardiovascular disease 10-years risk assessment score
- Volunteers
- 383 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiovascular Diseases (CVD), Coronary Artery Disease
wCAR-Austria: A Women-Specific Score to Assess Cardiovascular Risk in Women Aged 40 to 65
The wCAR-Austria Study is a multicentre, prospective, interventional study evaluating a novel women-specific cardiovascular risk score (wCAR) in 800 women aged 40-65 years across Austria.
- Conditions
- Cardiovascular Diseases (CVD), Coronary Artery Disease, Atheroscleroses
- Trial name
- wCAR-Austria (NCT07849127)
- Testing
- Arm 1: wCAR-CARE - Precision Prevention (Arm A), Guideline-directed standard of care
- Where
- Austria
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- Women's Heart Austria
Hypertension
Technology-enabled Management Versus Usual Care for Blood Pressure
Two arm parallel randomized clinical trial
- Trial name
- HrtEx (NCT05479461)
- Testing
- Digital Hypertension Management System, Usual Care
- Where
- 3 sites in United States
- Volunteers
- 200 people
- Sponsor
- Stanford University
Myocardial Infarction, Adherence, Patient
Remote Monitoring System for Patients, Who Had Myocardial Infarction
one-centered, open, prospective, non-randomized, controlled clinical study will be aimed at creating remote monitoring system for patients' condition and the development of methodological approaches and its usage for conducting…
- Trial name
- NCT04424368
- Testing
- The remote monitoring system
- Where
- Russia
- Volunteers
- 250 people
- Sponsor
- Ryazan State Medical University
Hypertension, Elderly (People Aged 65 or More)
Dynamic and Isometric Strength Training in Older Adults With Hypertension
This feasibility study aims to evaluate the effects of dynamic strength training and isometric strength training on cardiovascular health indicators, mental health, and neuromuscular fitness in older adults with hypertension.
- Trial name
- Dynamic and Is (NCT07448818)
- Testing
- Dynamic Strength Training, Isometric Strength Training, No supervised intervention Control
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Raphael Mendes Ritti Dias
Heart Rate, Heart Rate Variability
Air Pollution, Epigenetics and Cardiovascular Health: A Human Intervention Trial
In this study, the pills formulated are being used to try to ameliorate the effect of air pollution on epigenetic changes, specifically DNA methylation, potentially linked with particulate matter air pollution inhalation and…
- Conditions
- Heart Rate, Heart Rate Variability, Inflammation
- Trial name
- EPI-Air (NCT01864824)
- Testing
- methyl donor
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Cardio Vascular Disease, Metabolic Syndrome (MetS)
Norwegian Mental Illness Heart Health Study
Norwegian patients with severe mental illnesses (SMI), such as schizophrenia spectrum or bipolar disorder, lose on average 10 years of life compared to mentally healthy individuals. Much of this gap is due to heart disease.
- Conditions
- Cardio Vascular Disease, Metabolic Syndrome (MetS), Severe Mental Disorder, Schizophrenia and Schizophrenia Spectrum Psychosis
- Trial name
- NORMI-Heart (NCT07085923)
- Testing
- Lifestyle Intervention
- Where
- Norway
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Madeleine Elisabeth Angelsen
Cardiovascular Disease, Diabetes Mellitus
Living With Statins - The Impact of Cholesterol Lowering Drugs on Health, Lifestyle and Well-being
Background Statins are cholesterol lowering drugs that are prescribed to lower the risk of cardio-vascular diseases. The use of statins has increased markedly and it is now one of the most prescribed drugs in the world.
- Trial name
- LIFESTAT (NCT02255682)
- Testing
- Simvastatin, Q10
- Where
- Denmark
- Volunteers
- 35 people
- Sponsor
- University of Copenhagen
Stroke, Hypertension
Self-Management in Stroke Survivors
This is a feasibility study of using health-IT to promote self-management of risk factors in stroke survivors.
- Trial name
- NCT01875094
- Testing
- Self-Management / MTM using Health IT
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- University of Minnesota
Heart Failure, Depression
Cardiac Health, Mood, & Neuroimmune Activation
The study is designed to find out more about how mood and the nervous system affect the body's immune system. The investigators plan to study this in people who have been identified by their physician as being at-risk for the…
- Trial name
- NCT01615094
- Volunteers
- 456 people
- Sponsor
- University of California, San Diego