Clinical trials: Cardiovascular Adaption
Yoga, Pregnancy
Effect of Yoga in Pregnancy on Cardio-respiratory Adaptation to Challenge
Yoga has received considerable attention for its potential therapeutic benefits over the past decades and it gradually became object of scientific scrutiny.
- Conditions
- Yoga, Pregnancy, Autonomic Nervous System
- Trial name
- YOGADAPT (NCT04476368)
- Testing
- weekly yoga classes, walk
- Where
- 2 sites in Slovenia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Cardiovascular System
Vascular Adaptations to Single-Sprint Training
The long-term objective of this research line is to identify and implement an effective and feasible intervention capable of preventing and/or reducing the burden of cardiometabolic and obesity-related diseases that affect…
- Trial name
- VASST (NCT05727332)
- Testing
- Single-Sprint Training
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Mississippi, Oxford
Obesity, Diabetes
The Effect of Macronutrients in the Diet on Digestive and Cardiovascular Health
This study examined the effect of a 5-day HFD supplemented with specific fatty acids on gastrointestinal transit, appetite, food intake and substrate utilization.
- Conditions
- Obesity, Diabetes, Cardiovascular Diseases
- Trial name
- NCT01510223
- Testing
- Olive oil, Olive oil and fish powder, Olive oil and macadamia oil
- Where
- Ireland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Stroke, Hypertension
Validation And Turkish Cross-Cultural Adaptation of Stroke Knowledge Test
Cerebrovascular diseases are the leading cause of disability, work loss, and quality of life reduction, the third leading cause of death globally, and significantly impact hospital admissions and expenses.
- Trial name
- NCT06543121
- Testing
- Translating the Stroke Knowledge Test into Turkish and Related Processes, Validity, Internal consistency and Reliability
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Bilgi University
Aphasia, Stroke
Adapted Solution Focused Therapy for People With Aphasia (SOFIA Trial)
Around one third of stroke survivors will have aphasia, which means they will have difficulty talking, understanding, reading or writing.
- Trial name
- SOFIA (NCT03245060)
- Testing
- Adapted Solution Focused Brief Therapy
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- City, University of London
Hypertension
Health Impacts of a Climate Change Adaptation Strategy to Address Drinking-water Salinity in Coastal Bangladesh
Background (brief): 1. Burden: Excessive salinity is common in groundwater aquifers across south-western coastal Bangladesh. Higher adult mean systolic and diastolic blood pressure and increased risk of gestational hypertension…
- Trial name
- NCT02746003
- Testing
- Managed Aquifer Recharge water
- Where
- Bangladesh
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Spatial Neglect, Stroke
Transcranial Stimulation (tDCS) and Prism Adaptation in Spatial Neglect Rehabilitation
The present study aims to compare the relative therapeutic efficacy of prism adaptation therapy combined with real versus sham tDCS.
- Conditions
- Spatial Neglect, Stroke, Cerebrovascular Disorders, Cerebral Infarction
- Trial name
- NCT02080286
- Testing
- Prism Adaptation, Anodal tDCS
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oxford
Postmenopausal, Hypertension
Cardiometabolic Adaptations to Concurrent Training: Effect of Effort Configuration on Postmenopausal Women
The main objectives of this project are to assess the effects of a 20-week concurrent training program on neuromuscular adaptations, body composition, cardiometabolic health, quality of life, mood state, physical self-perception…
- Trial name
- CARE+E (NCT07377383)
- Testing
- Concurrent Training Program
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Hypertension, Train Sickness
The Effect of Training Given to With Hypertension
The study was conducted to examine the effects of the training given according to the Roy Adaptation Model on the sleep and quality of life of individuals with hypertension.
- Trial name
- NCT06521242
- Testing
- Patient Education
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Kader ÖZTÜRK
Sodium Excess, Hypertension
Effects of a Six-Day Whole-Diet Intervention on Taste Perception and Dietary Behaviour in Young Adults
This study aims to investigate the effects of a specific diet modification on the pleasantness, desire, and saltiness intensities of selected foods and an ad libitum breakfast buffet through a randomized controlled trial with…
- Conditions
- Sodium Excess, Hypertension, Salty Taste
- Trial name
- NCT07726394
- Testing
- Experimental: Increased Salty Food Intake, Experimental: Decrease Salty Food Intake, Active Comparator: Maintain Usual Diet
- Where
- Malaysia
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Sunway University
Cardiovascular Disease
Effect of ACE Genotype on Cardiovascular Rehabilitation
The study aims to systematically investigate the interaction between training modality, ACE genotype and disease in heart patients whom complete a cardiovascular rehabilitation program.
- Trial name
- ACE-REHAB (NCT02845063)
- Testing
- concentric cardiovascular training, eccentric cardiovascular training, ACE genotyping
- Where
- 2 sites in Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Balgrist University Hospital
Menstrual Cycle, Luteal Phase Progesterone Levels
Corpus Luteum Function and Cardiovascular Adaptation in a Natural MOCK Cycle.
In infertility treatment, embryos are created in vitro after eggs have been fertilised by sperm using in vitro fertilisation or intracytoplasmic sperm injection techniques.
- Conditions
- Menstrual Cycle, Luteal Phase Progesterone Levels, Luteal Phase Adaptation, MOCK Cycle
- Trial name
- CLEAR (NCT07648381)
- Testing
- Blood samples for the analysis of biomarkers., Transvaginal ultrasound for follicle and endometrium measurements., Mean Arterial Pressure measurement.
- Where
- Belgium
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Hypertension
ADAPT-Altering Diet for African American Populations to Treat Hypertension
The purpose of the study is to develop a culturally appropriate DASH intervention and test the effectiveness of the intervention lower blood pressure in a group of African American participants at risk for developing hypertension…
- Trial name
- ADAPT (NCT00621569)
- Testing
- Dietary Approaches to Stop Hypertension-The DASH diet, Intervention with no dietary component - information regarding useful life skills
- Where
- United States
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Diabetes Mellitus, Type 2, Obesity
Culturally-Adapted Diet for Puerto Rican Adults
This pilot project will determine whether a diet culturally-adapted to Puerto Ricans can effectively decrease cardiometabolic risk for diabetes.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- NCT03975556
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Normal Physiology, Stroke
Effects of Prism Adaption and rTMS on Brain Connectivity and Visual Representation
Background: After a stroke, the balance between the two halves of the brain can be lost. This may cause people to lose the ability to perceive a side of space. This is called neglect.
- Trial name
- NCT02911129
- Where
- United States
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Blood Pressure, Hypertension
Community-based Implementation of Adapted STAC
This study is being done to adapt the Staying Healthy After Childbirth (STAC) intervention for implementation among Black Women and Birthing Persons (WBP).
- Conditions
- Blood Pressure, Hypertension, Pregnancy Related, Health Equity
- Trial name
- NCT06689930
- Testing
- PDSA Cycles
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Congenital Heart Disease With Systemic Right Ventricle
Study of Adaptation of the Right Ventricle to Systemic Afterload
the first purpose of the study is to determine the adaptative mechanisms of right ventricle (RV) to systemic afterload, and the mechanisms of RV failure, in patients with congenital heart disease and subaortic RV, using cardiac…
- Trial name
- STARS (NCT02066506)
- Testing
- asymptomatic group, symptomatic group
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pregnancy Related, Heart Rate Variation (HRV)
Cardiovascular Research in EMbarazo and MAternity (EMMA). Study on Heart Rate Variability and Hemodynamic Adaptations During Pregnancy and Postpartum.
Heart rate variability (HRV) provides a non-invasive assessment of autonomic control of the nervous system over the heart. During pregnancy, the cardiovascular system adapts significantly, affecting HRV and hemodynamics.
- Conditions
- Pregnancy Related, Heart Rate Variation (HRV), Hemodynamics
- Trial name
- EMMA (NCT07376616)
- Testing
- Assessment of HRV and blood pressure
- Where
- Spain
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Cardiovascular Diseases
Impact of Statin Therapy on Adaptations to Aerobic Exercise
The purpose of this study is to determine how different doses of a statin affect muscle health and exercise.
- Trial name
- NCT03360916
- Testing
- Lipitor 20Mg Tablet, Lipitor 80Mg Tablet, Exercise Program
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center