Clinical trials: Cardiopulmonary Resuscitation (CPR)
Pediatric Cardiac Arrest (Simulated), Cardiopulmonary Resuscitation, Simulation Training
Effect of Bed Height on Chest Compression Quality and Provider Biomechanics During Pediatric CPR Simulation
High-quality chest compressions are critical for outcomes after pediatric cardiac arrest, yet rescuer ergonomics and bed height may adversely affect compression quality and fatigue.
- Conditions
- Pediatric Cardiac Arrest (Simulated), Cardiopulmonary Resuscitation, Simulation Training, In-Hospital Cardiac Arrest, Rescuer Fatigue During CPR
- Trial name
- NCT07329842
- Testing
- Fixed Standard Bed Height (58 cm), Anthropometry-Based Bed Height (Patella Midpoint), Anthropometry-Based Bed Height (Lower One-Third Patella-ASIS)
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Cardiac Arrest, Out-Of-Hospital
Brain Oxygenation During Cardiopulmonary Resuscitation
The study is aimed to assess (a) the incidence of hyperoxia at the point of return of spontaneous circulation (ROSC) and (b) the role of arterial blood oxygen partial pressure to brain oxygenation during out-of-hospital cardiac…
- Trial name
- NCT03464123
- Testing
- Standard cardiopulmonary resuscitation
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Helsinki University Central Hospital
Stereotype-threat, COVID-19
Stereotype Threat Effect on CPR Performance in Covid-19 Intensive Care Units: A Randomised Controlled Mannequin Study
Stereotype threat (ST) is an important issue that has been studied repeatedly in the psychology literature. ST is the thought that a person will be negatively evaluated and judged regarding a negative stereotype that belongs to…
- Trial name
- NCT05074446
- Testing
- stereotype threat manipulation
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Cardiopulmonary Arrest Outcome
Protein S100 Beta as a Predictor of Resuscitation Outcome
Management of cardiac arrest is complicated by the lack of a readily available tool identifying individuals who are likely to be successfully resuscitated.
- Trial name
- NCT00814814
- Where
- 2 sites in Israel
- Volunteers
- 313 people
- Sponsor
- Shaare Zedek Medical Center
Cardiopulmonary Arrest, VA-ECMO
Optimized CT-imaging Protocol in VA-ECMO Patients After CPR
Veno-arterial (VA) extracorporal membrane oxygenation (ECMO) is an increasingly applied method in patients under cardiopulmonary resuscitation (CPR), who are regularly examined with a contrast-enhanced computed tomography to…
- Trial name
- NCT05290805
- Testing
- ECMO flow rate reduction
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Cost Analysis, Length of ICU Stay
An Artificial Intelligence Model for Intensive Care Length of Stay, Neurological Outcome and Costs Estimation After Cardiopulmonary Resuscitation: a Cohort Study.
The study aims to overview patients registered to Bezmialem Vakıf University Hospital Intensive Care Unit after successive cardiac arrest resuscitation from October 2010 to September 2025.
- Conditions
- Cost Analysis, Length of ICU Stay, Neurological Outcome
- Trial name
- NCT07210866
- Testing
- no physical or medical interventions
- Volunteers
- 5,000 people
- Sponsor
- Bezmialem Vakif University
Cardiac Arrest, Cardiopulmonary Resuscitation
Evaluation of eCPR Survivors
A cardiac arrest event has severe impact on the patient´s health-related quality of life. Survival of cardiac arrest does not innately translate to favorable quality of life.
- Conditions
- Cardiac Arrest, Cardiopulmonary Resuscitation, Extracorporeal Membrane Oxygenation Complication, Myocardial Infarction
- Trial name
- NCT05339854
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Charite University, Berlin, Germany
Out-of-Hospital Cardiac Arrest, Extracorporeal Cardiopulmonary Resuscitation
Refractory Cardiac Arrest Treated On Field By ECMO
Out-of-hospital cardiac arrest without resumption of spontaneous circulatory activity despite advanced medical resuscitation is considered refractory.
- Trial name
- ReCATOBE (NCT06397417)
- Testing
- Data collection
- Where
- France
- Volunteers
- 840 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cardiopulmonary Resuscitation
Assessment of CPR Skills Acquisition and Retention: Impact of Technology and Self-training
Cardiopulmonary resuscitation (CPR) is an emergency maneuver used on a victim who is in cardiac arrest. Early and efficient CPR, with a focus on chest compressions, is a key element in increasing victim survival.
- Trial name
- TrainCPR (NCT05493189)
- Testing
- Additional autonomous training sessions
- Where
- Portugal
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Cardiopulmonary Resuscitation, Simulation Training
The Effect of Attention Distractor on the Quality of Chest Compression
The investigators plan to investigate the effect of attention distractor on the quality of chest compression during cardiopulmonary resuscitation.
- Trial name
- NCT03124290
- Testing
- paced auditory serial addition test (PASAT)
- Where
- South Korea
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Inje University
Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR)
The AIR-CPR Study: AI-Guided Chest Compressions
The AIR-CPR project aims to improve survival rates for patients with Out-of-Hospital Cardiac Arrest (OHCA) by utilizing Artificial Intelligence (AI) to optimize chest compression locations.
- Conditions
- Out-of-hospital Cardiac Arrest (OHCA), Cardiopulmonary Resuscitation (CPR), Aortic Valve Compression, Precision Resuscitation
- Trial name
- AIR-CPR (NCT07431710)
- Testing
- Device: AI-Enhanced Arterial Waveform Monitor (AIR-CPR App), AI-Guided Chest Compression Repositioning, Transesophageal Echocardiography (TEE)
- Where
- Taiwan
- Volunteers
- 255 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiopulmonary Resuscitation
Manual and Mechanical Chest Compression During In-hospital Witnessed Cardiac Arrests Using Cerebral Oximetry
Post-resuscitation neurological impairment is associated with morbidity and especially with late mortality. Thus, because good neurological outcome is vital for a successful resuscitation, it is essential to have sufficient…
- Trial name
- NCT03238287
- Testing
- Mechanical chest compression, Manuel chest compression
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Eskisehir Osmangazi University
Cardiac Arrest
Evaluation of the Quality of Cardio-Pulmonary Resuscitation (CPR) in Cardiac Arrest Patients
The prognosis of cardiac arrest patients is generally poor. Recent studies have showed that the high quality of CPR increases the survival after cardiac arrest.
- Trial name
- NCT00951704
- Where
- 2 sites in Finland
- Volunteers
- 1,000 people
- Sponsor
- Tampere University Hospital
Cardiac Arrest, Heart Arrest
ECPR for Refractory Out-Of-Hospital Cardiac Arrest
In the U.S. alone, over 300,000 people per year have sudden out-of-hospital cardiac arrest (OHCA), and less than 1 out of 10 survive.
- Conditions
- Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest
- Trial name
- EROCA (NCT03065647)
- Testing
- Expedited Transport With Mechanical CPR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Out-Of-Hospital Cardiac Arrest, Cardiac Arrest
Compression Only CPR Versus Standard CPR in Out-Of-Hospital Cardiac Arrest - A Randomized Survival Study
Out-of-hospital cardiac arrest (OHCA) is one of the leading causes of mortality in the industrialized world. Bystander CPR before arrival of the Emergency Medical Service (EMS) is associated with an increased chance of survival.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Cardiac Arrest, Cardiopulmonary Resuscitation
- Trial name
- TANGO2 (NCT03981107)
- Testing
- Chest Compression Only CPR (CO-CPR) performed by trained bystanders after instructions from dispatchers, Standard CPR (S-CPR) performed by trained bystanders after instructions from dispatchers
- Where
- 2 sites in Italy, Sweden
- Volunteers
- 3,260 people
- Sponsor
- Karolinska Institutet
Cardiopulmonary Arrest
Compare Outcomes of CPR Between the Video-laryngoscopy (VL) Users and the Direct-laryngoscopy (DL) Users
This is a clinical study based on the analysis of video-clip data of cardiopulmonary resuscitation (CPR) and clinical data for out of hospital cardiac arrest patients between 2011 and 2015.
- Trial name
- NCT03256019
- Testing
- Endotracheal Intubation
- Volunteers
- 600 people
- Sponsor
- Konkuk University Medical Center
Heart Arrest, Cardiac Arrest, Out-Of-Hospital
Synergy of Elevation of the Head and Thorax and REBOA During Out-of-Hospital Cardiac Arrest
Long-term neurological outcome after successful resuscitation of cardiac arrest remains poor, mainly due to cerebral hypoperfusion and severe hypoxic-ischemic brain injuries.
- Conditions
- Heart Arrest, Cardiac Arrest, Out-Of-Hospital, Cardiopulmonary Arrest, Cardiopulmonary Resuscitation
- Trial name
- GRAVITY2 (NCT06537492)
- Testing
- REBOA, Head-Up Cardiopulmonary Resuscitation (AHUP-CPR), Mechanical Chest Compression Device with Active Chest Decompression
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Grenoble
Cardiac Arrest (CA)
Does Increasing the Compression Pause From 3 to 5 Seconds in Mechanical Compression Devices Increase Ventilation Success Rate and Return of Spontaneous Circulation?
To give chest compressions during cardiopulmonary resuscitation (CPR), mechanical chest compression devices can be used. During synchronous 30:2 CPR, the standard setting on these devices leave an automated 3-second chest…
- Trial name
- LUCASVP (NCT06824961)
- Testing
- 5-second ventilation pause duration during mechanical CPR, 3-second ventilation pause duration during mechanical CPR
- Where
- 2 sites in Netherlands
- Volunteers
- 692 people
- Sponsor
- Amsterdam UMC, location VUmc
Cardiopulmonary Resuscitations
Leadership Instructions Improve Cardiopulmonary Resuscitation in a High Fidelity Simulation
Whether teaching leadership with a short debriefing has a positive influence on the performance of cardiopulmonary resuscitation remains largely unknown.
- Trial name
- NCT00884559
- Testing
- instruction
- Where
- Switzerland
- Volunteers
- 237 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Cardiac Arrest, Cardiopulmonary Arrest
Lowlands Saves Lives: A Randomized Trial Comparing CPR-quality Between Face-to-face vs. Lifesaver VR Training
The objective of the Lowlands Saves Lives trial is to compare the quality of cardiopulmonary resuscitation (CPR) between face-to-face versus Lifesaver Virtual Reality smartphone application trained participants using a randomized…
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT04013633
- Testing
- Lifesaver virtual reality training, Face-to-face training
- Where
- Netherlands
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center