Clinical trials: Cardiometabolic Diseases
Exergaming, Metabolic Syndrome
Immersive Virtual Reality Exergames and Office Workers' Cardiometabolic Health
The worldwide increasing of prevalence of non-communicable diseases has grown the recognition of necessity for identifying the modifiable risk in preventing and managing these diseases.
- Trial name
- NCT06556784
- Testing
- 12-week at-home immersive virtual reality exergame
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Guangzhou University
Obesity, Prediabetic State
Effect of Melatonin on Cardiometabolic Risk- FULL
In a 12 week double-blind, placebo-controlled randomized trial, 120 subjects with obesity (BMI≥30 kg/m2) and pre-diabetes (HbA1c, 5.7-6.4%) will be randomly assigned 1:1 to receive either placebo or 2 mg of controlled-release…
- Trial name
- NCT02681887
- Testing
- Melatonin
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Metabolic Syndrome
Resistance Training and Cardiometabolic Risk
Little is known on the effects of resistance training (RT) alone in individuals with metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUHO).
- Trial name
- NCT06054594
- Testing
- Resistance exercise
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Université du Québec a Montréal
Dementia, Mild Cognitive Impairment (MCI)
Combating Alzheimer's Through Sleep and Exercise
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
- Trial name
- CASE (NCT04855630)
- Testing
- Elemind Neuromodulation Headband, Exercise Routine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Obesity, Metabolic Syndrome
Fish or Nuts? Dietary Effects on Cardiometabolic Risk Factors and Persistent Organic Pollutants
Obesity represents one of the most important public health challenges for the societies. Although excess energy intake and physical inactivity are major causes of obesity and cardiometabolic disorders, emerging evidence has…
- Conditions
- Obesity, Metabolic Syndrome, Diabetes
- Trial name
- NCT02589756
- Testing
- The fatty fish group, The nut group, The control group
- Where
- Norway
- Volunteers
- 120 people
- Sponsor
- Oslo University Hospital
Overweight and Obesity
Interindividual Variation in Response to Green Coffee
The study is a multifaceted approach to investigate the effects of regular consumption of green coffee rich in polyphenols (hydroxycinnamic acids) on weight, body composition, cardiometabolic and inflammatory biomarkers in a…
- Trial name
- GREENCOF (NCT06204445)
- Testing
- Green coffee, Roasted coffee
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto de Ciencia y Tecnología de Alimentos y Nutrición
Obesity
Comparison of Anthropometric Parameters and Cardiometabolic Risk Factors Among Subjects With Overweight and Obesity
The study was aimed at comparing four different anthropometric parameters to cardiometabolic risk factors in overweight and obese subjects (Body Mass Index (BMI)≥25)
- Trial name
- NCT04318288
- Testing
- Observational
- Where
- Italy
- Volunteers
- 1,214 people
- Sponsor
- Azienda Ospedaliera Specializzata in Gastroenterologia Saverio de Bellis
Type 2 Diabetes
Nationwide Assessment of Cardiovascular Risk Factors: in Chinese Patients With Type 2 Diabetes
The objective of this study is to evaluate the level of control of cardiovascular disease risk factors, including blood pressure, blood lipid, and blood glucose, in out patients with type 2 DM in 6 representative regions in…
- Trial name
- 3B (NCT01128205)
- Where
- China
- Volunteers
- 25,000 people
- Sponsor
- China Cardiometabolic Registries
Cardiometabolic Health
Trajectory Study: Predicting Cardiometabolic Health in Adolescents and Young Adults Based on Childhood Fitness, Sleep, and Diet
The Trajectory study aims to determine whether childhood aerobic fitness, sleep quality, and diet quality predict cardiometabolic health during puberty and early adulthood, independently of adiposity.
- Trial name
- Trajectory (NCT06913985)
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Arkansas Children's Hospital Research Institute
Percutaneous Coronary Intervention, Heart Failure
REgiStry-based Cardiovascular qUality improvEment Research
The goal of this registry-based observational study is to establish a comprehensive management plan, which focus on medical therapy, cardiac rehabilitation and active post-market surveillance of medical devices, in patients with…
- Conditions
- Percutaneous Coronary Intervention, Heart Failure, Cardiometabolic Syndrome, Structural Heart Abnormality
- Trial name
- RESCUER (NCT06137885)
- Testing
- Cardiac rehabilitation, Active post-market surveillance of devices, Multi-omics approach to precision medicine
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Peking University Third Hospital
Transgenderism, Insulin Sensitivity/Resistance
Puberty Suppression and Cardiometabolic Health
This observational study will evaluate the effect of puberty suppression on insulin sensitivity, metabolic rate and vascular health among transgender female youth at baseline and 6 months after initiation of a gondoatropin…
- Conditions
- Transgenderism, Insulin Sensitivity/Resistance, Endothelial Dysfunction, Vascular Stiffness
- Trial name
- NCT04482374
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Mitral Valve Insufficiency
Determinants of the Progression and Outcome of Mitral Regurgitation
Mitral regurgitation (MR) is one of the most frequent valve lesions, both in North America and in Europe, and its prevalence is increasing with the aging of the population.
- Trial name
- PROGRAM (NCT01835054)
- Testing
- Blood biomarkers, DNA collection, Echocardiography
- Where
- 4 sites in Belgium, Canada and 1 more
- Volunteers
- 440 people
- Sponsor
- Laval University
Motivational Interviewing, Cardiometabolic Index
The Effect of Motivational Interviewing on Anthropometric Measurements, Eating Attitudes, and Cardiometabolic Index in Overweight and Obese Patients
The Effect of Motivational Interviewing on Anthropometric Measurements, Eating Attitudes, and Cardiometabolic Index in Overweight and Obese Patients
- Conditions
- Motivational Interviewing, Cardiometabolic Index, Obesity, Overweight (BMI > 25)
- Trial name
- NCT06947798
- Testing
- motivational interviewing, Diet, Physical exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Saltuklu Aile Sağlığı Merkezi
Diabete Type 1, Diabete Type 2
Effects of LP-LDL® on Lipid Metabolism, Glycemic Control, Inflammatory Markers, and Cognitive Function in Individuals With Prediabetes and Diabetes Mellitus
This randomized, double-blind, placebo-controlled clinical trial investigates the effects of the probiotic LP-LDL® (Lactobacillus plantarum ECGC 13110402) on lipid metabolism, glycemic control, inflammatory biomarkers, and…
- Conditions
- Diabete Type 1, Diabete Type 2, Prediabetes
- Trial name
- NCT07373392
- Testing
- Lactobacillus plantarum ECGC 13110402
- Where
- 2 sites in Denmark
- Volunteers
- 210 people
- Sponsor
- Aalborg University
Diet, Healthy, Obesity
FEAST Perinatal Support Program Intervention
Latino individuals face an elevated risk of adverse health outcomes during pregnancy, impacting both the birthing parent and the baby with potential long-term chronic health conditions.
- Conditions
- Diet, Healthy, Obesity, Cardiometabolic Syndrome
- Trial name
- NCT06715787
- Testing
- FEAST Perinatal Support Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
Metabolic Syndrome
Ginsenoside Improve Metabolic Syndrome
Aim : Investigated the effects of Korean red ginseng supplementation on metabolic parameters such as cholesterol, blood pressure and glucose. Randomized Control Trial.
- Trial name
- NCT02034136
- Testing
- Ginsenoside, Dietary fiber fill
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- CHA University
Spinal Cord Injuries, Cardiometabolic Diseases
High Intensity Interval Exercise SCI
This study will determine if the implementation of a home-based telehealth high intensity interval exercise-training (HIIT)program can significantly improve cardiometabolic health and physical function in a cohort of individuals…
- Trial name
- NCT04940598
- Testing
- high intensity interval exercise, No-exercise control group
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Alabama at Birmingham
Dietary Modification, Weight Loss
Feasibility of a Postpartum Lifestyle Intervention on the Cardiometabolic Risk Profile of GDM Women
The goal of the study is to investigate the effect of a lifestyle intervention program (adoption of exclusive breastfeeding, healthy diet and regular physical activity) on minimizing postpartum weight retention among women with…
- Conditions
- Dietary Modification, Weight Loss, Physical Activity, Breastfeeding
- Trial name
- DEPART (NCT02872402)
- Testing
- Lifestyle intervention, Active control lifestyle intervention
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Laval University
Overweight, Obesity
Network Meta-analyses of Artificially Sweetened Beverages and Cardiometabolic Risk
Sugars especially in form or sugar-sweetened beverages (SSBs) have been singled out as one of the prime culprits in the dual epidemics of obesity and diabetes.
- Trial name
- NCT02879500
- Testing
- Diet beverages
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Metabolic Syndrome X, Insulin Resistance
Impact of Meal Order on Postprandial Cardiometabolic Risk Markers
The order in which the different components of a meal are eaten may have impact on the postprandial metabolic responses to carbohydrates, fat and proteins.
- Conditions
- Metabolic Syndrome X, Insulin Resistance, Hyperinsulinism, Glucose Metabolism Disorders
- Trial name
- NCT03358745
- Testing
- Standard meal, bread/butter as starter, Standard meal with soup as starter, Standard meal with cheese as starter
- Where
- 2 sites in Sweden
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Lund University