Clinical trials: Cardio-pulmonary Function
Carcinoma, Renal Cell
Alternative Schedule Sunitinib in Metastatic Renal Cell Carcinoma: Cardiopulmonary Exercise Testing
The purpose of this study is to determine the effect of a sunitinib administration schedule 2/1 (2 weeks of treatment followed by 1 week without) compared to a schedule 4/2 (4 weeks of treatment followed by 2 weeks without) on…
- Trial name
- ASSET (NCT03109015)
- Testing
- Sunitinib
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Coronary Artery Bypass Graft Surgery Patients
Improving Outcomes and Quality of Life After CABG
The principal objective to this randomized trial is to compare the efficacy of two strategies of intra-operative hemodynamic management during cardiopulmonary bypass among patients undergoing primary elective coronary artery…
- Trial name
- NCT00256620
- Testing
- Mean arterial pressure during cardiopulmonary bypass 80 mmHg vs. customized
- Where
- United States
- Volunteers
- 412 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Heart Disease
The Effect on Fluid Balance After Cardiac Surgery After Use of Two Different Priming Protocols
"The impact on fluid loading after cardiac surgery by use of two different priming solution" Fluid overloading with oedema formation is a regular finding following on-pump cardiac surgery and may contribute to postoperative organ…
- Trial name
- NCT01511120
- Testing
- Tetraspan, acetated Ringer's solution
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Haukeland University Hospital
Endothelial Dysfunction, Acute Kidney Injury
Optimizing Pulsatility During Cardiopulmonary Bypass
Cardiopulmonary bypass during cardiac surgery provides blood flow to the body during surgery but has adverse effects on different organs.
- Trial name
- NCT05344573
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Colorado, Denver
Non-Small-cell Lung Cancer
Characterization of Peripheral Muscle Function in Patients With Non-small-cell Lung Cancer
Rationale: With 1.6 million new cases diagnosed each year and 1.3 million deaths, lung cancer is the leading cancer-related death worldwide and it represents a pressing health issue.
- Trial name
- NCT01885754
- Where
- Canada
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Pulmonary Hypertension
Assessment of Cardiac Function Using Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing (CMR-CPET)
What problems limit patients' response to exercise? Using exercise cardiac magnetic resonance imaging to assess the heart's response, with simultaneous measurement of respiratory oxygen and carbon dioxide levels to assess the…
- Trial name
- CMR-CPET (NCT04729777)
- Testing
- Combined Cardiovascular Magnetic Resonance and Cardiopulmonary Exercise Testing
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Royal Free Hospital NHS Foundation Trust
Cardiorespiratory Fitness, Metabolic Health
Validation of a Novel Incremental Step Test for Assessment of Cardiopulmonary Fitness and Ventilatory Thresholds in Adults
The purpose of this single-group diagnostic validation and test-retest reliability study is to determine whether a novel Incremental Step Test (IST) can accurately assess cardiorespiratory fitness and ventilatory thresholds in…
- Conditions
- Cardiorespiratory Fitness, Metabolic Health, Cardiac Function, Pulmonary Function
- Trial name
- VALID-IST (NCT07829003)
- Testing
- Cardiopulmonary Exercise Test, Incremental Step Test
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Heriot-Watt University
Cognitive Function, Cardiopulmonary Function
Commuter Air Pollution Intervention Study
Traffic related air pollution is a well-recognised and much studied contributor to smog and is linked to a number of adverse health outcomes.
- Conditions
- Cognitive Function, Cardiopulmonary Function, Saliva Stress Hormones, Air Pollution Exposure
- Trial name
- CAPI (NCT02277002)
- Testing
- Cabin Air Filtration
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Health Canada
Heart Failure, Chronic Heart Failure
Wearable Tissue Oximetry During Arm Cuff Occlusion, Walking, and Standing Tests in Outpatients With Chronic Heart Failure
This prospective, single-center, observational pilot study evaluated an investigational wearable tissue oximeter (NIRSense Argus Oximetry System, also called Envello Core) in adult outpatients with chronic heart failure in New…
- Trial name
- NCT07874386
- Testing
- Argus Oximetry System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- NIRSense Inc.
Respiratory Depression, Blood Pressure
Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust
The US EPA Clean Air Multiyear research program is moving toward a multi-pollutant approach to the assessment of air pollution in response to recommendations by the NRC 2004 and the BOSC in 2005.
- Trial name
- DEPOZ (NCT01874834)
- Testing
- ozone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Intensive Care Unit Acquired Weakness
The Effect of Inspiratory Muscle Training on Diaphragmatic Function in Mechanically Ventilated Patients
In this study, the effect of inspiratory muscle training on diaphragmatic functions will be investigated radiologically in mechanically ventilated patients.
- Trial name
- NCT05303623
- Testing
- Conventional Physiotherapy, Conventional Physiotherapy+ inspiratory muscle training, inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Demiroglu Bilim University
Coronary Artery Disease, Cardiac Disease
Effects of Early Telerehabilitation in Coronary Artery Bypass Surgery Patients
The aim of this study was to investigate the effects of phase I and early phase II rehabilitation with telerehabilitation method and sleep hygiene training on physical capacity, cardiac functions, anxiety level, quality of life…
- Trial name
- NCT06240702
- Testing
- Telerehabilitation Group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Necmettin Erbakan University
COVID-19, MIS-C Associated With COVID-19
Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C
Acute coronavirus disease 2019 (COVID-19) infection can include cardiac and pulmonary manifestations as well as post-infectious complications such as multisystem inflammatory syndrome (MIS-C), also known as pediatric inflammatory…
- Trial name
- NCT05205642
- Testing
- Cardiopulmonary exercise test (CPET), Peripheral Arterial Tonography (PAT) using the EndoPAT™ device, Endothelin
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Lung Cancer, Non Small Cell Lung Cancer
Low Volume High Intensity Interval Training in Operated Lung Cancer Patients
Patients included in the study will be randomly divided into 2 groups using appropriate randomization programs. All patients will be given exercise training individually for 24 sessions using a bicycle ergometer under the…
- Trial name
- NCT05837429
- Testing
- Low Volume High Intensity Exercise Training, Aerobic Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Heart Arrest, Ventricular Fibrillation
Observational and Diagnostical Study on Transient Allostatic Responses of Thyroid Function After Cardiopulmonary Resuscitation
Time-limited adaptive responses of thyroid function are common in the critically ill. About 70% of all patients treated on intensive care units develop a so-called non-thyroidal illness syndrome (NTIS) or TACITUS (thyroid…
- Conditions
- Heart Arrest, Ventricular Fibrillation, Ventricular Flutter, Ventricular Tachycardia
- Trial name
- Thyro-CPR (NCT04392258)
- Testing
- TSH determination, FT4 determination, FT3 determination
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Ruhr University of Bochum
Breathing Exercises, Disability Physical
Effect of Inspiratory Muscle Training on Cardiopulmonary Capacity in Wheelchair Rugby Athletes
The goal of this clinical trial is to learn about in inspiratory muscle training on cardiorespiratory capacity, pulmonary function, respiratory muscle strength, sports skills, and quality of life of wheelchair rugby athletes.
- Conditions
- Breathing Exercises, Disability Physical, Athletes
- Trial name
- NCT06134778
- Testing
- Inspiratory Muscle Training
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Centro Universitário Augusto Motta
Coronary Heart Disease (CHD), Heart Failure
Community Exercise Treating Effect on Cardiopulmonary Disease Patients
The goal of this clinical trial is to learn if community-based exercise training can benefit patients aged 18 to 85 with diminished cardiovascular and pulmonary function.
- Conditions
- Coronary Heart Disease (CHD), Heart Failure, Cardiomyopathy, COPD
- Trial name
- NCT07154355
- Testing
- community-based exercise training
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Guangdong Provincial People's Hospital
Cardiac Rehabilitation, Exercise Therapy
Exercise Prescription in Cardiac Rehabilitation Mediated by Autonomic Function
Cardiac rehabilitation (CR) is an essential secondary prevention component in the treatment of cardiovascular diseases and one of the most cost- effective clinical interventions.
- Conditions
- Cardiac Rehabilitation, Exercise Therapy, Autonomic Nervous System Imbalance, Treatment Outcomes
- Trial name
- EXCARMA (NCT07288840)
- Where
- 2 sites in Portugal
- Volunteers
- 90 people
- Sponsor
- Instituto Politécnico de Leiria
Heart and Lung Transplant
Nordic Study in Cardiac and Lung Transplantation: Outcome in Relation to Cyclosporine Microemulsion C2 Levels
The main purpose of this study is to identify cyclosporine C2 levels during 12 months treatment , while cyclosporine microemulsion dosages are adjusted based on C0 cyclosporine blood samples, and retrospectively correlate C2…
- Trial name
- NCT00154193
- Testing
- cyclosporine
- Where
- Switzerland
- Volunteers
- 190 people
- Sponsor
- Novartis Pharmaceuticals
Type 1 Diabetes Mellitus
Cardiopulmonary Fitness, Lung Function, Muscular Oxygen Saturation, and Quality of Life in T1DM
The purpose of this study is to compare the differences of 1. cardiopulmonary fitness 2. lung function 3. muscular oxygen saturation 4. quality of life between type 1 diabetes mellitus and healthy adults.
- Trial name
- NCT01727661
- Testing
- exercise testing with near-infrared spectroscopy, lung function testing, quality of life
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital