Clinical trials: Cardiac Electrophysiology
Coronary Artery Disease, Electrophysiology
Database Registry of the Intermountain Heart Collaborative Study
The purpose of the registry is to collect and analyze clinical and laboratory data and tissue samples from patients who are diagnosed with any type of heart disease and to collect the same information and samples from healthy…
- Conditions
- Coronary Artery Disease, Electrophysiology, Cardiovascular Disease
- Trial name
- NCT00406185
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Intermountain Health Care, Inc.
Inherited Arrhythmias and Valvulopathies
Molecular Mechanism Identification in Inherited Arrhythmias and Valvulopathies From Induced Pluripotent Stem Cells
The recent developments of research on iPS (induced pluripotent stem) cells lead to the establishment of mature cell lines such as cardiomyocytes or valvular interstitial cells with genetic and cellular characteristics of the…
- Trial name
- Diag-iPS (NCT01734356)
- Testing
- Skin biopsies
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Ventricular Tachycardia
Anesthetic Management in Patients Undergoing Epicardial Ablation
The study is a retrospective study and is descriptive in nature. In this study, the investigators aimed to emphasize the importance of anesthesia management by cardiac risk assessment of patients undergoing epicardial ablation…
- Trial name
- NCT06538987
- Testing
- percutaneous epicardial ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University
Cardiac Electrophysiology
Transvenous Lead Removal Post-Market Clinical Study
This prospective, multicenter, post-market clinical study was designed to evaluate the outcomes of lead extraction of cardiovascular implantable electronic devices (CIED) using Cook catheter and lead extraction devices for any…
- Trial name
- NCT03688412
- Testing
- Cook lead extraction devices
- Where
- 9 sites in United States, Germany and 2 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Cook Research Incorporated
Rhinoplasty Surgery
Effects of Dexmetomidine and Remifentanil Used for Controlled Hypotension in Septorhinoplasty Surgery on Cardiac Electrophysiology: Prospective Randomized Study
Our aim in this treatment was to reveal the effects of remifentanil and dexmetomidine, which we used to provide controlled hypotension in septorhinoplasty surgery, on cardiac electrophysiology.
- Trial name
- Effects of Dex (NCT06138574)
- Testing
- Dexmedetomidine, Remifentanil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Binge Drinking
Afferent Neurocardiac Signals, Cue Reactivity, and Cognitive Control
Conscious attempts to regulate alcohol use are often undermined by automatic attention and arousal processes activated by alcohol cues, as well as by diminished ability to inhibit in-the-moment behaviors.
- Trial name
- NCT05369169
- Testing
- Resonance breathing, Low demand cognitive task
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Dexmedetomidine, General Anesthesia
Effects of Dexmedetomidine on Cardiac Electrophysiology in Patients Under General Anesthesia During Perioperative Period
Perioperative stress may increase the incidence of adverse events in the cardiovascular system and lead to poor prognosis. Dexmedetomidine is a highly selective α2 adrenergic receptor agonist, which can inhibit stress response…
- Conditions
- Dexmedetomidine, General Anesthesia, Cardiac Electrophysiology, Cardiac Function
- Trial name
- NCT04577430
- Testing
- Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Yangzhou University
Healthy Volunteers
Genetic Sources of Variability of the Adaptation of the Ventricular Repolarisation
The main objective is to research for genetic factors involved in the extreme modifications of the QT interval of the electrocardiogram in answer to a pharmacological stimulation (sotalol) and physiological stimulation in the…
- Trial name
- Generepol (NCT00773201)
- Testing
- Sotalol 80 mg
- Where
- France
- Volunteers
- 997 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Atrial Fibrillation
Enhanced Diagnostics for Early Detection of Atrial Fibrillation
Paroxysmal atrial fibrillation can only be diagnosed during episodes when the arrhythmia is present. The investigators hypothesize that the activation of the atrial myocardium resulting in the p-wave of the ecg should display…
- Trial name
- DETECT-AF (NCT02270112)
- Testing
- ECG
- Where
- Switzerland
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Left Bundle Branch Block, Transcatheter Aortic Valve Replacement
HV Electrophysiology Study In Transcatheter Aortic Valve Implantation Patients
TAVI induced LBBB is a complication that occurs between 7 and 65 % of the cases, numbers that differ considerably between devices.
- Conditions
- Left Bundle Branch Block, Transcatheter Aortic Valve Replacement, Transcatheter Aortic Valve Implantation
- Trial name
- HESITATE (NCT02659137)
- Testing
- HV measurement
- Where
- Netherlands
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Periodontitis, Cardiac Electrophysiology
Effects of Periodontitis on Heart Rate Variability
Periodontitis is a chronic inflammatory disease associated with systemic inflammatory burden and possible alterations in autonomic nervous system regulation.
- Trial name
- NCT07735312
- Testing
- Non-surgical periodontal therapy
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Respiratory Depression, Blood Pressure
Cardiopulmonary Responses to Exposure to Ozone and Diesel Exhaust
The US EPA Clean Air Multiyear research program is moving toward a multi-pollutant approach to the assessment of air pollution in response to recommendations by the NRC 2004 and the BOSC in 2005.
- Trial name
- DEPOZ (NCT01874834)
- Testing
- ozone
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Environmental Protection Agency (EPA)
Atrial Fibrillation, Hypertension
Irbesartan for the Prevention of Atrial Arrhythmias and Cardiac Electrical Remodeling in Patients With Hypertension and Permanent Pacemakers
The purpose of this study is to determine whether irbesartan will reduce the rate of recurrent atrial high rate episodes and the development of clinical sustained atrial fibrillation in patients with hypertension and permanent…
- Trial name
- NCT00225667
- Testing
- Irbesartan
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Connolly, Stuart, M.D.