Clinical trials: Cardiac Catheterization
Pulmonary Hypertension, Pulmonary Thromboembolisms
Electrical Impedance Tomography for Assessment of Pulmonary Hypertension
Pulmonary hypertension is a serious and progressive disease that is difficult to treat and diagnose, mainly because its symptoms are nonspecific and often delay recognition. Early diagnosis is a major challenge.
- Trial name
- NCT07453017
- Testing
- Electrical Impedance Tomography (EIT), Right Heart Catheterization
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- University of Sao Paulo General Hospital
Fasting, Cardiac Catheterization
Comparison Between Fasting and no Fasting Before Interventional Coronary Intervention on the Occurrence of Adverse Events
Traditionally, patients are asked to fast prior to invasive cardiac procedures. There exists neither clear evidence nor guidance about the benefits of this.
- Conditions
- Fasting, Cardiac Catheterization, Percutaneous Coronary Intervention
- Trial name
- TONIC (NCT04116346)
- Testing
- Oral intake allowed
- Where
- France
- Volunteers
- 736 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Anesthesia Emergence Delirium
Dexmedetomidine Versus Ketamine Versus Magnesium Sulfate for the Prevention of Emergence Agitation Following Sevoflurane Induced Anesthesia in Cardiac Catheterization in Pediatrics
Emergence agitation (EA) is a post-operative behavioral disturbance was first reported in early 1960s. EA is a term used to describe non purposeful restlessness and agitation, thrashing, crying or moaning, disorientation and…
- Trial name
- NCT06077539
- Testing
- Dexmedetomidine, Ketamine, Magnesium
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Pulmonary Hypertension, Congestive Heart Failure(CHF)
Observational Study of Patients Undergoing Diagnostic Right Heart Catheterization
The objective of this observational pilot study is to collect HemoCept device data from subjects undergoing diagnostic right heart catheterization (RHC) procedures.
- Conditions
- Pulmonary Hypertension, Congestive Heart Failure(CHF), Valve Disease, Heart
- Trial name
- NCT07224906
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- HemoCept Inc.
Coronary Artery Disease
Subcutaneous Nitroglycerin to Facilitate Trans-radial Access.
Femoral artery approach to perform coronary procedures is considered the standard technique for vascular access due to optimal catheter control, lower thromboembolic complications and immediate access due to the large diameter of…
- Trial name
- NITRAD-Sub (NCT03304496)
- Testing
- Nitroglycerin 100 MCG/ML Injectable Solution, Saline Solution
- Where
- Mexico
- Volunteers
- 1,400 people
- Sponsor
- Instituto Nacional de Cardiologia Ignacio Chavez
Right Ventricular Dysfunction
Incidence, Impact and Mechanisms of Perioperative Right VEntricular Dysfunction (IMPRoVE)
A study to see how common right heart failure (right ventricular dysfunction) after major surgery is, and to investigate if right ventricular dysfunction causes worse patient outcomes after surgery.
- Trial name
- IMPRoVE (NCT05827315)
- Testing
- Echocardiography, T1 Cardiovascular Magnetic Resonance, Right heart catheterisation and coronary sinus blood sampling
- Where
- 3 sites in United Kingdom
- Volunteers
- 175 people
- Sponsor
- NHS National Waiting Times Centre Board
Patient Satisfaction, Vascular Access Complication
Radial vs. State-Of-The-Art Femoral Access for Bleeding and Access Site Complication Reduction in Cardiac Catheterization (REBIRTH)
This is a phase IV, prospective, open label, randomized-controlled study that will compare radial access with state-of-the-art femoral access in patients without ST-segment elevation acute myocardial infarction undergoing cardiac…
- Trial name
- REBIRTH (NCT04077762)
- Testing
- Radial Access, State-of-the-art femoral access with 18 gauge needle, State-of-the-art femoral access with 21 gauge needle
- Where
- 6 sites in United States
- Volunteers
- 3,266 people
- Sponsor
- Minneapolis Heart Institute Foundation
Coronary Artery Disease
Quantification of Myocardial Blood Flow Using Dynamic PET/CTA Fused Imagery
This observational prospective clinical study is to develop software tools to fuse coronary anatomy data obtained from CT coronary angiography with dynamic PET data to noninvasively measure absolute myocardial blood flow, flow…
- Trial name
- NCT04221594
- Testing
- Invasive Cardiac Catheterization (ICA), Coronary Computed Tomographic Angiogram (CCTA), Dynamic Cardiac Positron Emission Tomography (dPET)
- Where
- 6 sites in United States, South Korea
- Volunteers
- 68 people
- Sponsor
- Emory University
Heart Diseases
Fasting Versus Non-fasting on Outcomes and Satisfaction Prior to Cardiac Catheterization
Moderate sedation is used in the catheterization laboratory relieve the anxiety and discomfort associated with access and other aspects of the procedure.
- Trial name
- CALORI (NPO) (NCT05851872)
- Testing
- Coronary angiogram, Right heart catheterization
- Where
- United States
- Volunteers
- 169 people
- Sponsor
- Virginia Commonwealth University
Anomalies Vascular
Radifocus (Terumo) Versus Silverway (Asahi) to Deliver Catheters During Cardiac Catheterization
In some cases the standard J-tip guidewire cannot deliver the catheter into the aortic root, because of arterial loops or spasm.
- Trial name
- RADVES (NCT05231889)
- Testing
- Silverway guidewire, Radifocus guidewire
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ziekenhuis Oost-Limburg
Heart Failure, Diastolic, Echocardiography
Assessment of Left Ventricular Filling Pressure by Applying Artificial Intelligence Algorithms to Left Atrial Speckle-tracking Echocardiography
The goal of this single-center, prospective, observational study is to validate a software package based on an artificial intelligence algorithm for automated non-invasive estimation of LVFP against invasively measured ones by…
- Trial name
- LVEDP (NCT05768698)
- Testing
- Software algorithm
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Istituto Auxologico Italiano
Cardiac Arrest
Intraosseous Access During Pediatric Resuscitation
The purpose of this study was to compare the Jamshidi, the BIG, the Cook, the EZIO intraosseous devices to standard peripheral venous catheterization during pediatric resuscitation.
- Trial name
- IOCPR (NCT02305511)
- Testing
- Peripheral venous catheterization, Jamshidi, BIG
- Where
- Poland
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Hypertrophic Cardiomyopathy, Left Ventricular Outflow Obstruction
NHLBI SESAME (SEptal Scoring Along Midline Endocardium) Multi-Center Prospective Study Using Improvised Off-Label Devices
This is an early study of a catheter-based minimally invasive procedure called SESAME to slice thick heart muscle as described below.
- Conditions
- Hypertrophic Cardiomyopathy, Left Ventricular Outflow Obstruction, Systolic Anterior Motion
- Trial name
- NCT07806149
- Testing
- SESAME Procedure
- Where
- 8 sites in United States
- Volunteers
- 200 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Treatment Procedure, Mortality
Treatment Management and Factors Affecting Mortality in Retroperitoneal Hemorrhage Due to Cardiac Catheterization; Single Center Experience
Bleeding complications after cardiac catheterization have been reviewed previously, but there are very few studies on retroperitoneal hematoma and appropriate treatment of patients is not well defined.
- Trial name
- NCT03006120
- Testing
- Retroperitoneal hematoma due to cardiac catheterization
- Volunteers
- 68 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Anterior Wall Acute Myocardial Infarction
Evaluation of the Delivery of Optimized Supersaturated Oxygen Therapy to Treat Patients With an Acute Heart Attack
The purpose of this study is to evaluate the feasibility of the delivery of SuperSaturated Oxygen (SSO2) Therapy for 60 minutes selectively into the left main coronary artery (LMCA).
- Trial name
- NCT01630707
- Testing
- SuperSaturated Oxygen (SS02) Therapy
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- TherOx
Scleroderma, Systemic, Hypertension, Pulmonary
Stress Echocardiography in the Detection of Pulmonary Arterial Hypertension in Systemic Sclerosis Patients
The purpose of this study is to assess the value in terms of sensitivity, specificity and likelihood ratio of the stress echocardiography in the screening of pulmonary arterial hypertension in patients with systemic sclerosis and…
- Trial name
- NCT01202045
- Where
- Canada
- Sponsor
- Paul Farand
Myocardial Ischemia, Cardiac Catheterization
Effect of Reactive Hyperemia and Ultrasound-guided Puncture on the Success Rate of Radial Artery Cannulation (RadialHUS)
Aims: to evaluate the success rate of radial artery cannulation in patients undergoing cardiac catheterization, using different methods such as palpation, hyperemia or ultrasound-guided puncture, together or each method…
- Trial name
- RadialHUS (NCT05364463)
- Testing
- Methods for cannulating the radial artery in a cardiac catheterization
- Where
- Spain
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Heart Catheterization
Randomized, Open Label Study of Dabigatran Etexilate in Elective Percutaneous Coronary Intervention
To assess whether two doses of dabigatran etexilate (110 mg twice daily (b.i.d) and 150 mg twice daily (b.i.d)) as compared to unfractionated heparin (UFH), both in addition to a standard dual antiplatelet regimen, provide…
- Trial name
- NCT00818753
- Testing
- dabigatran 110 mg, dabigatran 150 mg, unfractionated heparin
- Where
- 4 sites in Netherlands
- Volunteers
- 53 people
- Sponsor
- Boehringer Ingelheim
Cardiac Catheterization
Sugammadex Versus Neostigmine in Pediatric Less Than Two Years Undergoing Cardiac Catheterization
This study hypothesizes that Sugammadex may has more appropriate recovery profile than neostigmine in pediatric cardiac patients undergoing cardiac catheterization.
- Trial name
- NCT04258007
- Testing
- Reversal Neostigmine, Reversal Sugammadex
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mansoura University
Preprocedure Anxiety
Impact of Virtual Reality on Pre-procedural anxieTy Prior to Heart cathEterIzAtion - VR-THEIA
The primary aim of this study is to test the hypothesis that use of VR combined with standard procedural education will result in less pre-procedural anxiety than standard procedural education alone among patients undergoing…
- Trial name
- VR-THEIA (NCT03662607)
- Testing
- Virtual reality experience
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Corewell Health West