Clinical trials: Cardiac Arrest
Arrhythmia, Heart Arrest
Public Access Defibrillation (PAD) Community Trial
To measure survival to hospital discharge of patients with out-of-hospital cardiac arrest in community units (e.g., apartment or office buildings, gated communities, sports venues, senior centers, shopping malls) served by…
- Conditions
- Arrhythmia, Heart Arrest, Heart Diseases, Myocardial Infarction
- Trial name
- NCT00004560
- Testing
- defibrillator
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Heart Arrest
Patient Acuity Rating: a Tool to Prevent In-Hospital Cardiac Arrest
The purpose of this study is to evaluate the accuracy of medical personnel in their ability to predict the likelihood of non-intensive care (ICU), ward patients to clinically deteriorate (defined as a cardiac arrest, unplanned…
- Trial name
- PAR (NCT01082991)
- Testing
- Preemptive Rapid Response Team intervention
- Where
- United States
- Sponsor
- University of Chicago
Severe Sepsis, Cardiac Arrest
Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes
A hospitals manual method of patient monitoring will be implemented in an automated system and supported by an early patient deterioration detection for timely escalation.
- Conditions
- Severe Sepsis, Cardiac Arrest, Respiratory Failure
- Trial name
- NCT01692847
- Where
- United Kingdom
- Volunteers
- 678 people
- Sponsor
- Philips Healthcare
Hypothermia, Heart Arrest
Hypothermia and Hemostasis After Cardiac Arrest
This is a sub-study to the Time-differentiated Therapeutic Hypothermia (TTH48, ClinicalTrials.gov Identifier: NCT01689077). TTH48 compares 24 with 48 hours of therapeutic hypothermia at a target temperature of 32-34°C in…
- Conditions
- Hypothermia, Heart Arrest, Hemostasis, Coagulants
- Trial name
- NCT02258360
- Testing
- Therapeutic hypothermia
- Where
- Denmark
- Volunteers
- 82 people
- Sponsor
- University of Aarhus
Hypothermia, Cardiac Arrest
Therapeutic Hypothermia With Propofol in Survival and Neurological Prognoses After Cardiac Arrest
Therapeutic hypothermia has been proven to significantly improve the survival and neurological prognoses in patients resuscitated from cardiac arrest.
- Trial name
- NCT02367755
- Testing
- Propofol, Lorazepam
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Far Eastern Memorial Hospital
Cardiac Arrest During and/or Resulting From A Procedure
Prehospital Laryngeal Tube vs. Bag-Valve Mask Ventilation Used by Paramedics During CPR
During CPR bag-valve mask ventilation is difficult for basically skilled rescuers. Ventilation may be inefficient or with too high pressures result in stomach inflation and aspiration.
- Trial name
- NCT01718795
- Testing
- Bag-valve mask or laryngeal tube ventilation
- Where
- Austria
- Volunteers
- 78 people
- Sponsor
- Michael Baubin, MD
Ventricular Fibrillation
Recognizing Ventricular Fibrillation From an Area of a Mobile Phone
Recognition of out of hospital cardiac arrest (OHCA) during an emergency call is based on standardized questions concerning the symptoms of OHCA. With this method cardiac arrest is recognized in 50-83% of cases.
- Trial name
- NCT01824212
- Where
- 2 sites in Finland
- Volunteers
- 22 people
- Sponsor
- North Karelia Central Hospital
Heart Arrest
Evaluation of Drainable Volume Measurements During VA-ELS
Veno-arterial extracorporeal life support (VA-ELS) is used to support patients with acute cardiac failure. In that context, sufficient drainable venous volume is crucial for reliable and adequate support.
- Trial name
- NCT02326506
- Testing
- VA-ELS pump speed variations
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- Maastricht University Medical Center
In-hospital Cardiac Arrest
National Cardiac Arrest Survey
The aim of this study is to describe incidence of "in-hospital" deaths and outcomes after attempted cardiac arrest resuscitation, availability of resuscitation equipment and medical staff training in state Hospitals of Sri Lanka.
- Trial name
- NCAS (NCT02368392)
- Testing
- Exposure for cardiac arrests
- Where
- Sri Lanka
- Volunteers
- 537 people
- Sponsor
- Ministry of Health, Sri Lanka
Cardiovascular Diseases, Heart Diseases
Proarrhythmic Medicines and Primary Cardiac Arrest
To determine whether treatment with antidepressant, anticonvulsant, and antiarrhythmic drug therapies having the potential for proarrhythmia increased the risk of primary cardiac arrest.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Heart Arrest, Hypertension
- Trial name
- NCT00005253
- Sponsor
- University of Washington
Cardiac Arrest, Cardiopulmonary Resuscitation
Quantitative Measurement of Cardiopulmonary Resuscitation (CPR) During In Hospital Cardiac Arrest
The design of this protocol is a prospective observational study to objectively measure the rate, depth and quality of chest compressions and ventilations delivered during cardiac arrest in the Pediatric Intensive Care Unit…
- Trial name
- Q-CPR (NCT00628693)
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Children's Hospital of Philadelphia
Cardiac Arrest, Brain Injury
Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest
In this study, children who survive cardiac arrest will be evaluated whether 24 or 72 hours of whole body hypothermia (cooling) during recovery is better to help prevent brain injury and improve outcome.
- Trial name
- NCT00797680
- Testing
- 72 hours hypothermia, 24 hours hypothermia
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of Pittsburgh
Heart Arrest
Combined Vasopressin, Methylprednisolone, and Epinephrine for Inhospital Cardiac Arrest
A randomized controlled trial did not show benefit of vasopressin versus epinephrine in inhospital cardiac arrest. Preceding laboratory data suggest that combined vasopressin and epinephrine ensure long-term survival and…
- Trial name
- NCT00411879
- Testing
- Vasopressin, Epinephrine, and Steroids
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Athens
Heart Diseases, Ventricular Arrhythmia
Prognostic Significance of T Wave Alternans
To evaluate whether T Wave Alternans can predict ventricular arrhythmias and sudden cardiac death (SCD) in a prospective epidemiologic natural history study.
- Conditions
- Heart Diseases, Ventricular Arrhythmia, Ventricular Fibrillation, Death, Sudden, Cardiac
- Trial name
- NCT00006501
- Testing
- ECG
- Where
- United States
- Volunteers
- 549 people
- Sponsor
- Columbia University
Out of Hospital Cardiac Arrest, Neurologic Symptoms
Can Optic Nerve Sheath Diameter Measurement Predict Negative Neurological Outcome ?
This study is designed as a multicenter, prospective, cohort clinical study. The out of hospital cardiac arrest (OHCA) patients presenting to the adult emergency departments of the participating hospitals will render the study…
- Trial name
- NCT02637258
- Testing
- Ultrasonographic Measurements of Optic Nerve Sheath Diameter
- Where
- 19 sites in Turkey (Türkiye)
- Volunteers
- 203 people
- Sponsor
- Emergency Medicine Association of Turkey
Cardiac Arrest, Pulseless Electrical Activity
REASON 1 Trial: Sonography in Cardiac Arrest
The aim of this study is to investigate the predictive value of the presence or absence of cardiac activity by bedside ultrasound during cardiac arrest.
- Conditions
- Cardiac Arrest, Pulseless Electrical Activity, Asystole
- Trial name
- NCT01446471
- Where
- 7 sites in United States, Canada
- Volunteers
- 793 people
- Sponsor
- University of Massachusetts, Worcester
Hypothermia, Heart Arrest
Haemostasis and Therapeutic Hypothermia
The purpose of this study is to investigate, if the haemostasis is impaired in cardiac arrest patients during therapeutic hypothermia compared with normothermia.
- Trial name
- NCT02179021
- Where
- Denmark
- Volunteers
- 26 people
- Sponsor
- University of Aarhus
Out-of-hospital Cardiac Arrest
The PulsePoint Randomized Controlled Trial
"Sudden cardiac arrest" occurs when someone's heart stops beating unexpectedly. Each year, more than 45,000 Canadians have a cardiac arrest.
- Trial name
- NCT01746290
- Testing
- PulsePoint notification
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen's University
Cardiac Arrest, Hypothermia
The Cardiac Effects of Prolonged Hypothermia After Cardiac Arrest
This PhD study is a sub study in a randomized clinical controlled multicenter trial named "TTH48" (ClinicalTrials.gov Identifier: NCT01689077).
- Trial name
- NCT02066753
- Testing
- Mild therapeutic hypothermia
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Cardiac Arrest
Basic Life Support Termination of Resuscitation Implementation Study
In Ontario, most people who experience a cardiac arrest at home (when their heart stops beating) only receive basic life support from Primary Care Paramedics (PCPs) and all are transported to the hospital.
- Trial name
- NCT00370461
- Where
- 7 sites in Canada
- Volunteers
- 350 people
- Sponsor
- Sunnybrook Health Sciences Centre