Clinical trials: Capsule Endoscopy
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Crohn's Disease
Evaluation of Capsule Endoscopy in Patients With Suspected Crohn's Disease
The aim of this study is to validate the ability of Capsule Endoscopy (CE) to accurately diagnose small bowel (SB) Crohns disease in patients with symptoms of abdominal pain and diarrhea.
- Trial name
- MA-51 (NCT00487396)
- Testing
- Capsule Endoscopy
- Where
- 11 sites in United States, Canada and 2 more
- Volunteers
- 98 people
- Sponsor
- Medtronic - MITG
Colonic Diseases
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) Preparation and Procedure
The purpose of this study is to evaluate the effect of a modified Prep and procedure on colon cleansing level and capsule excretion rate.
- Trial name
- NCT00885209
- Where
- 5 sites in Spain
- Volunteers
- 127 people
- Sponsor
- Medtronic - MITG
Colonic Diseases
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon
This multi-center, prospective, cohort study of 394 subjects that are indicated for standard colonoscopy due to suspected or known colonic disease examines the Given Diagnostic System and the PillCam Colon Capsule in comparison…
- Trial name
- NCT00440791
- Testing
- PillCam Colon capsule endoscopy
- Where
- 7 sites in United States, Israel
- Volunteers
- 40 people
- Sponsor
- Medtronic - MITG
Intestinal Disease, Inflammatory Bowel Diseases
Validation of CapsoVision CapsoCam® SV-3 Capsule Endoscopy System
To validate an updated version of CapsoCam® SV-3 Endoscopy System brand name CapsoCam Plus™) with respect to the reproducibility of the system to capture and download small bowel images in a manner consistent with the predicate…
- Conditions
- Intestinal Disease, Inflammatory Bowel Diseases, Crohn Disease, Ulcer
- Trial name
- NCT04573959
- Testing
- SV-3 Capsule Endoscopy
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Capso Vision, Inc.
Healthy Volunteers
Safety Evaluation of Bowel Cleansing Regimen for PillCam® COLON 2 Capsule Endoscopy
This study is designed to evaluate the safety of a preparation regimen for PillCam® Colon 2 Capsule Endoscopy.
- Trial name
- NCT01575093
- Testing
- The preparation regimen
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Healthy Volunteers
Video Capsule Endoscopy to Investigate the Safety and Tolerability of Lumiracoxib in the Small Bowel
This study is designed to investigate the potential differences in GI safety and tolerability in the small bowel between lumiracoxib, conventional non-selective NSAID (naproxen) with a proton pump inhibitor (omeprazole), or…
- Trial name
- NCT00350155
- Testing
- Lumiracoxib
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 150 people
- Sponsor
- Novartis
Small Intestine Disease, Small Intestine Cancer
Data Collection of PillCamTM SB3 Capsule Endoscopy and Device-Assisted Enteroscopy Routine Care Procedures (GPS Study)
A prospective, multicenter, post-market, minimal risk, observational study designed to collect PillCamTM SB3 capsule endoscopy (CE) procedures and subsequent device-assisted enteroscopy (DAE) procedures data (double balloon…
- Conditions
- Small Intestine Disease, Small Intestine Cancer, Small Intestinal Ulcer Bleeding, Small Intestine Obstruction
- Trial name
- NCT05450393
- Sponsor
- Medtronic - MITG
Upper Gastrointestinal Symptoms
Comparative Study of MCCE With/Without Tether vs Conventional Upper Endoscopy in Patients With Upper Abdominal Symptoms
A prospective single blinded, tandem study, comparing a magnetically controlled capsule with or without a tether (MCC or MCC-T) with conventional upper endoscopy for the diagnosis of patients with upper abdominal symptoms.
- Trial name
- NCT04605302
- Testing
- MCC/MCC-T, Standard gastroscopy
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- AnX Robotica Corp.
Colonoscopy, Endoscopy
Evaluation of PillCam® Colon 2 Capsule Endoscopy Regimen
The purpose of the study is to test the effect of a bowel preparation and boosts regimen on PillCam® procedure, colon cleanliness and capsule excretion time.
- Trial name
- NCT01185002
- Testing
- PillCam® COLON 2 procedure using MgC boosts, PillCam® COLON 2 procedure using Suprep boosts, PillCam® COLON 2 procedure using reduced dose of Suprep boosts
- Where
- 7 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Ulcerative Colitis
Evaluation of PillCam IBD Capsule Endoscopy System in Visualization of Lesions in the Colon Indicative of Ulcerative Colitis Disease
Study Hypothesis UC Disease affects the colon. PillCam IBD may be used for visualization of the colon mucosa in UC Disease patients.
- Trial name
- UC (NCT02025777)
- Testing
- Capsule Endoscopy
- Where
- 2 sites in Israel, Spain
- Volunteers
- 30 people
- Sponsor
- Medtronic - MITG
Small Bowel Bleeding
A Post Market Trial Assessing the Accuracy of Normal Mode Reading vs. ProScan Reading With the NaviCam SB System. This is a Comparison of Retrospectively Obtained Capsule Endoscopy Videos With a New AI Reading Tool; no New Interventions Will be Completed.
NaviCam ProScan is an artificial intelligent (AI) assisted reading tool designed to aid small bowel capsule endoscopy reviewers in decreasing the time to review capsule endoscopy images for adult patients in whom the capsule…
- Trial name
- PROCEED (NCT07633847)
- Testing
- Video capsule endoscopy, Phase II = Data analysis by Independent Readers, Phase III = Data Analysis by Expert Readers
- Where
- 3 sites in United States
- Volunteers
- 92 people
- Sponsor
- AnX Robotica Corp.
Esophageal Varices
"Evaluation of the PillCam™ESO Capsule in the Detection of Esophageal Varices
The purpose of the study is to access the accuracy of the PillCam Eso capsule in identifying the presence of suspected esophageal disease in patients undergoing surveillance or screening for esophageal disease by standard…
- Trial name
- MA-37 (NCT00481416)
- Testing
- PillCam Eso
- Where
- 5 sites in United States, Australia and 1 more
- Volunteers
- 318 people
- Sponsor
- Medtronic - MITG
Crohn's Disease
The Efficacy of Open Label Infliximab for the Induction and Maintenance of Mucosal Healing in Small Bowel Crohn's Disease Assessed Through Wireless Camera Endoscopy
This is a pilot study to estimate the efficacy of infliximab in inducing and maintaining healing of lesions in the mucosa of subjects with Crohn's disease involving their small bowel.
- Trial name
- ICE (NCT01181765)
- Testing
- Infliximab 5 mg/kg body weight infused over 2 hours
- Where
- 2 sites in Canada
- Volunteers
- 1 people
- Sponsor
- Janssen Inc.
Colonic Disease, Ulcerative Colitis
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in Detection & Classification of Ulcerative Colitis
To evaluate the ability of the PillCam® Colon Capsule Endoscope to detect and classify Ulcerative colitis
- Trial name
- NCT00604422
- Where
- 3 sites in Hong Kong, Singapore and 1 more
- Volunteers
- 97 people
- Sponsor
- Medtronic - MITG
Colorectal Cancer, Polyp, Colonic
Technical Feasibility Evaluation of Mucosal Staining During Colon Capsule Endoscopy (CCE) Procedure in Colorectal Cancer (CRC) High Risk Population, When Using MB-MMX
A prospective, single-center, single-arm, non-randomized, post-market pilot study evaluating the technical feasibility of mucosal staining during COLON2 Capsule Endoscopy (CCE) procedure in population at high risk for Colorectal…
- Trial name
- NCT05022719
- Testing
- PillCam Colon2 procedure with MB-MMX
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Medtronic - MITG
Upper Gastrointestinal Hemorrhage
A Pilot and Feasibility Study to Evaluate Capsule Endoscopy
This study is aimed at assessing the capability of the PillCam Platform using the PillCam ESO 2 Capsule in: Determining whether there is 1) active bleeding in the Upper gastrointestinal (UGI) tract, 2) identifying the anatomic…
- Trial name
- MA-79 (NCT00974701)
- Testing
- PillCam ESO2
- Where
- 2 sites in Hong Kong, Israel
- Volunteers
- 50 people
- Sponsor
- Medtronic - MITG
Colonic Diseases
Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) Night Procedure
The purpose of this study is to evaluate the effect of the night procedure in regards to colon cleansing level and capsule excretion rate.
- Trial name
- NCT00951587
- Testing
- PillCam™ (Capsule Endoscopy)
- Where
- 2 sites in Germany
- Volunteers
- 49 people
- Sponsor
- Medtronic - MITG
Known Crohn Disease Subjects
Monitoring Disease Activity Using Video Capsule Endoscopy (VCE) in Crohn's Disease (CD) Subjects
This study is designed to evaluate the performance of VCE in the assessment of mucosal inflammation 6 months after the first VCE procedure
- Trial name
- NCT01942720
- Testing
- Capsule endoscopy and Ileocolonoscopy tests
- Where
- 15 sites in United States
- Volunteers
- 74 people
- Sponsor
- Medtronic - MITG
Gastric Disease
PillBot™ - Remotely Controlled Capsule Endoscopy
The PillBot System is an endoscopic capsule imaging system intended for visualization of the stomach. In contrast to currently used passive capsule endoscopy systems, and FDA cleared active magnetic system, the PillBot System…
- Trial name
- NCT06212206
- Testing
- PillBot
- Volunteers
- 20 people
- Sponsor
- Endiatx