Clinical trials: Cancer Screening
Colorectal Cancer
Health Literacy Interventions to Overcome Disparities in CRC Screening
In the proposed project the investigators will evaluate two different follow-up approaches to improve low income patients' completion of initial and annual colorectal cancer (CRC) screening using the Fecal Immunochemical Test…
- Trial name
- NCT02360605
- Testing
- automated telephone reminder, prevention coordinator, Health literacy appropriate education and demonstration
- Where
- United States
- Volunteers
- 620 people, healthy volunteers welcome
- Sponsor
- Louisiana State University Health Sciences Center Shreveport
Cervical Cancer
Testing an Implementation Science Tool to Increase Cervical Cancer Screening in Mombasa, Kenya
Cervical cancer is the most common cancer in women in sub-Saharan Africa, and the majority of cervical cancer mortality occur in low and middle income countries (LMICs).
- Trial name
- NCT03514459
- Testing
- Systems Analysis and Improvement Approach
- Where
- Kenya
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Colorectal Cancer Screening
Colon Capsule Endoscopy (CCE) Versus Computed Tomographic Colonography (CTC) in the Identification of Colonic Polyps in a Screening Population.
The primary objective of this multicenter, prospective, randomized study is to assess the diagnostic yield of Colon Capsule Endoscopy (CCE) versus Computed Tomographic Colonography (CTC) in a screening population.
- Trial name
- TOPAZ (NCT02754661)
- Testing
- COLON Capsule endoscopy, Computed Tomographic Colonography
- Where
- 13 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Medtronic - MITG
Colorectal Cancer
Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion
Objectives: Colonoscopy and stool-based testing are the two predominant colorectal cancer (CRC) screening tests used in the US, and both reduce colorectal cancer mortality.
- Trial name
- NCT03598166
- Testing
- Septin9
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Peter S. Liang, MD MPH
Cancer
Post Market Evaluation of Aer-O-Scope Visualization
This will be a prospective multi-center, multi-national comparative non-blinded clinical investigation. Each subject will undergo back-to-back tandem colonoscopies with the Aer-O-Scope Colonoscope System and a conventional…
- Trial name
- NCT02926209
- Testing
- Aer-O-Scope (Colonoscopy), Colonoscopy (Conventional Colonoscope)
- Where
- 2 sites in United States, Israel
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- GI View Ltd.
Colorectal Cancer
Community Collaboration to Advance Racial/Ethnic Equity in CRC Screening
The goal of this pragmatic randomized clinical trial is to compare two colorectal (CRC) screening outreach approaches (FIT and Cologuard) in community health centers (CHC) in patients overdue for CRC screening.
- Trial name
- CARES (NCT05714644)
- Testing
- FIT kit Screening Test, Cologuard Screening Test
- Where
- 3 sites in United States
- Volunteers
- 5,127 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Stomach Neoplasms, Metaplasia
Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia
The presence and the extent of gastric intestinal metaplasia(IM) is a good indicator of high risk group of gastric cancer. Many methods was developed to survey it, including multiple gastric biopsy or methylene blue…
- Trial name
- IM (NCT01499576)
- Testing
- Acetic acid chromoendoscopy
- Where
- South Korea
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Konyang University Hospital
Colorectal Polyp, Colorectal Adenoma
Standard Colonoscopy Versus Colonoscopy With Endocuff Vision
This study seeks to compare colonoscopy results between a standard method and one using a distal scope attachment (Endocuff Vision).
- Conditions
- Colorectal Polyp, Colorectal Adenoma, Colon Cancer
- Trial name
- NCT03361917
- Testing
- Endocuff Vision
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Indiana University
Lung Carcinoma
Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV
This study tailors a shared decision making intervention for lung cancer screening in persons living with human immunodeficiency virus (HIV).
- Trial name
- NCT04682301
- Testing
- Behavioral Intervention, Discussion (focus group), Discussion (feedback on SDM)
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Hepatitis B, Liver Cirrhosis
Application of HBV Rapid Tests as a Tool for Wide-Use Screening
With over 280 000 chronic carriers, 2,500 new annual cases and 1,300 deaths each year, hepatitis B is currently a frequent and potentially severe disease in France, despite efforts towards prevention and effective care.
- Conditions
- Hepatitis B, Liver Cirrhosis, Carcinoma, Hepatocellular
- Trial name
- OPTISCREEN-B (NCT01767597)
- Testing
- ELISA testing, Rapid testing
- Where
- 5 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institut de Médecine et d'Epidémiologie Appliquée - Fondation Internationale Léon M'Ba
Breast Cancer
Decision-aid on Breast Cancer Screening
The present study aim to assess the effect of an interactive web decision aid on informed choice - measured via knowledge, attitudes and intentions concerning breast cancer screening - comparing the decision aid with a standard…
- Trial name
- NCT03097653
- Testing
- Decision-aid, Standard information
- Where
- 7 sites in Italy
- Volunteers
- 1,001 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
Colorectal Neoplasms
Interventions to Improve Colorectal Cancer Screening
We will evaluate if we can increase colorectal cancer screening rates by directly sending screening tests to patients rather than waiting for them to come to clinic visits.
- Trial name
- NCT00692211
- Testing
- Mailed fecal occult blood tests, Mailed fecal immunochemical tests
- Where
- United States
- Volunteers
- 404 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Lung Cancer
Co-Design and Pilot Testing of Peer-led Community Outreach to Improve Equity, Veteran-Centeredness and Uptake of Lung Cancer Screening
Co-design will be implemented to develop an innovative, Veteran-centered intervention (Vet Peer Connects program) that meets the needs of Black Veterans.
- Trial name
- VPC (NCT06389981)
- Testing
- Veterans peer connect Program
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Breast Carcinoma
Quantitative Transmission Imaging Compared With MRI as Supplemental Screening for High Lifetime Risk of Breast Cancer
This clinical trial compares the use of quantitative transmission imaging (QTI) to standard of care MRI as a supplemental screening tool for patients with a high lifetime risk of breast cancer.
- Trial name
- NCT07216274
- Testing
- QT Ultrasound Breast Scanner, Questionnaire Administration
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Barrett's Esophagus
Prospective Study to Compare the Efficacy of E.G.Scan to Detect Barrett's Esophagus Compared With Standard Endoscopy
The purpose of this study was to evaluate whether a disposable nasal endoscope called "E.G. Scan II" will visualize the esophagus as well as the standard test, sedated endoscopy.
- Trial name
- NCT02066233
- Testing
- EG Scan II (transnasal endoscopy), Standard Endoscopy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases
Culturally Tailored HPV Psychoeducational Multimedia Intervention
Community members ages 18 - 45 years old from the El Paso, Texas, U.S.-Mexico Border Region will be recruited to compare psychoeducational multimedia interventions focused on the human papillomavirus (HPV).
- Conditions
- Health Knowledge, Attitudes, Practice, Vaccine-Preventable Diseases, Intention, Adherence, Patient
- Trial name
- NCT06098690
- Testing
- Culturally Tailored Multimedia Psychoeducational HPV Intervention, General HPV Multimedia Psychoeducational Control Group
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- University of Texas, El Paso
Colonic Cancer
Evaluating Online Messages About Colon Cancer Screening
The goal of the study is to determine, using a choice-based approach, what messages (pulled from various online sites) people find more and less persuasive and shareable on the topic of colorectal cancer screening.
- Trial name
- NCT06134089
- Testing
- Perceived Effectiveness Prompt, Perceived Shareability Prompt
- Where
- United States
- Volunteers
- 2,210 people, healthy volunteers welcome
- Sponsor
- University of Utah
Human Papilloma Virus (HPV)
Evaluation of the Cobas® 4800 HPV Test for the Detection of High-grade Cervical Disease
This study provided data on the performance of the Cobas® 4800 HPV Test for identifying histologically confirmed high-grade cervical disease.
- Trial name
- NCT00709891
- Testing
- cobas® 4800 HPV Test
- Where
- 61 sites in United States
- Volunteers
- 47,208 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Colorectal Cancer
A Smartphone-Based Intervention to Improve Colorectal Cancer Screening in African American Men
The goal of this clinical trial is to test a new smartphone-based program designed to help African American men get screened for colorectal cancer (CRC).
- Trial name
- NCT06052202
- Testing
- CRC mHealth, Control
- Where
- United States
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- ISA Associates, Inc.
Colorectal Cancer
Flatbush FHC Proactive Colorectal Cancer Screening and Navigation
The proposed study is a randomized controlled pilot trial designed to assess the effectiveness and acceptability of a proactive screening outreach program on colorectal cancer screening rates on eligible patients in the Flatbush…
- Trial name
- NCT05646355
- Testing
- Proactive CRC Screening Outreach, Usual Care
- Where
- United States
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health