Clinical trials: Cancer Related Fatigue
Breast Neoplasm
CanRestoreFunction Cancer-related Fatigue ( CRF )
The goal of this randomized control trial is to determine if participating in an 8-week online cancer-related fatigue management intervention consisting of individualized exercise program, one-on-one goal setting and action plan…
- Trial name
- CRF (NCT05868187)
- Testing
- Exercise, Problem-Solving Session and Education
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Breast Cancer, Fatigue
The Role of Circadian Rhythms in Cancer-Related Symptoms
Emerging evidence indicates that circadian rhythms may be disrupted following cancer and its treatment, and that circadian rhythm disruption may be an underlying pathophysiological mechanism of cancer- and cancer…
- Conditions
- Breast Cancer, Fatigue, Cognitive Impairment, Sleep
- Trial name
- CHRONO (NCT04401189)
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Mitochondrial Dysfunction, COVID-19
In Vivo Investigation on Mitochondrial Dysfunction in Post-COVID Fatigue and Cancer Fatigue.
To date, little is understood regarding post-COVID fatigue or cancer fatigue though it is known to affect a large proportion of patients (10-70% depending on the population).
- Conditions
- Mitochondrial Dysfunction, COVID-19, Fatigue
- Trial name
- NCT05753228
- Testing
- MRI/ 3D Arterial Spin Labelling (ASL) and 1H magnetic resonance spectroscopy (MRS), Chalder Fatigue Scale, Health Questionnaire (EQ-5D-5L)
- Where
- Singapore
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Breast Cancer, Cognitive Dysfunction
Reducing Breast Cancer-related Fatigue and Improving Cognition With Non-Invasive Brain Stimulation
This study will test the preliminary efficacy of transcranial direct current stimulation (tDCS) to improve fatigue and cognition in women with a history of breast cancer and persistent fatigue.
- Conditions
- Breast Cancer, Cognitive Dysfunction, Fatigue
- Trial name
- NCT03143894
- Testing
- tDCS
- Where
- 3 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Multiple Myeloma, Fatigue
Treating Cancer-Related Fatigue Through Systematic Light Exposure (Light for Fatigue Study)
Cancer related fatigue (CRF) is the most common cancer side effect and can severely interfere with activities of daily living long after completion of medical treatment.
- Trial name
- NCT03119363
- Testing
- AYO light glasses (Experimental), AYO light glasses (Comparator)
- Where
- 3 sites in United States
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cancer Related Fatigue
Intervention Study Based on Real-world Data to Improve Quality of Life After Breast Cancer Treatment, the REBECCA-2 Study
The overall objective of the REBECCA studies at Stavanger University Hospital (SUH) is to improve the QoL of patients affected by cancer-related fatigue during and after end of treatment, by collecting multi-source real world…
- Trial name
- NCT06120595
- Testing
- REBECCA-assisted intervention 1, REBECCA-assisted intervention 2, Standard follow-up
- Where
- Norway
- Volunteers
- 81 people, healthy volunteers welcome
- Sponsor
- Helse Stavanger HF
Breast Cancer
Neurophysiological Evaluation of Training Effect on Cancer-Related Weakness
Breast cancer patients often suffer from long-term physical symptoms of weakness. In this study, investigators propose to compare how two different low intensity physical exercise training programs can improve handgrip strength…
- Trial name
- NCT02844504
- Testing
- Low Intensity Exercise Training 1, Low Intensity Exercise Training 2
- Where
- 2 sites in United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Gut Microbiome, Gastrointestinal Microbiome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.
- Conditions
- Gut Microbiome, Gastrointestinal Microbiome, Autism, Autism Spectrum Disorder
- Trial name
- NCT04031469
- Testing
- There is no intervention in this study
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- ProgenaBiome
Cancer, Cancer-Related Syndrome
Effects of a Multimodal Physical Exercise and Functional Rehabilitation Program on Fatigue, Pain, Functional Capacity and Quality of Life in Cancer Patients With Tumor Asthenia.
Tumor asthenia is the most common symptom associated with cancer and its treatment. Although the estimated prevalence varies between 60-90%, and it is considered the longest-lasting symptom in cancer patients, having the greatest…
- Conditions
- Cancer, Cancer-Related Syndrome, Fatigue
- Trial name
- NCT04761289
- Testing
- Multimodal Exercise and Functional Rehabilitation Program
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Salamanca
Neoplasms, Fatigue
Online Cancer-Related Fatigue Management
Many individuals who have had cancer experience functional limitations during and after their treatments. The most common side effect from cancer treatment that restricts cancer survivors' completion of daily activities is…
- Trial name
- NCT05017597
- Testing
- Rehabilitation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eastern Kentucky University
Fatigue, Chemotherapy
Prevalence, Severity and Determinants of Cancer-related Fatigue (CRF) in Asian Breast Cancer Patients
There is a paucity of studies that focus on the symptom burden of cancer patients in Singapore, particularly the clinical effects of cancer-related fatigue (CRF).
- Conditions
- Fatigue, Chemotherapy, Breast Cancer, Supportive Care
- Trial name
- NCT02304640
- Where
- Singapore
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Melanoma, Cognitive Impairment
Cognitive Function in Melanoma Patients Treated With Adjuvant Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) are a group of novel immunotherapies that boost the body's own defense against the cancer by improving the immune system's ability to recognize and destroy cancer cells.
- Conditions
- Melanoma, Cognitive Impairment, Fatigue, Sleep
- Trial name
- NCT04565769
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Fatigue, Pain
Molecular Determinants of Persistent Cancer Related Fatigue
The purpose of this study is to determine if inflammatory markers in blood as well as brain neurotransmitters (markers of in-brain activity and metabolism) are related to long-term or chronic fatigue.
- Conditions
- Fatigue, Pain, Poor Sleep Quality
- Trial name
- MDOF (NCT01980719)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Breast Cancer, Circadian Rhythms
The Effects of Light Therapy to Treat Cancer-related Side Effects
Severe fatigue, depression, sleep problems and cognitive impairment are the most commonly reported side effects of cancer treatment.
- Conditions
- Breast Cancer, Circadian Rhythms, Fatigue, Sleep Disturbance
- Trial name
- NCT04418856
- Testing
- Light Glasses (Experimental), Light Glasses (Comparison)
- Where
- Iceland
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Reykjavik University
Neoplasms, Fatigue
COMPANION: A Couple Intervention Targeting Cancer-related Fatigue
Chronic cancer-related fatigue (CCRF) is a disturbing condition that persists in up to 25% of cancer patients after completion of treatment.
- Trial name
- COMPANION (NCT05636696)
- Testing
- Samen Minder Moe (Dutch intervention name)
- Where
- 2 sites in Netherlands
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Mariët Hagedoorn
Leukemia, Children
Jacobson's Progressive Muscle Relaxation Technique on Children With Leukemia Undergoing Chemotherapy.
The goal of this clinical trial is to determine the effect of Jacobson's progressive muscle relaxation technique on anxiety and fatigue among children with leukemia undergoing chemotherapy.
- Conditions
- Leukemia, Children, Fatigue Related to Cancer Treatment, Anxiety
- Trial name
- JPMRT (NCT06631196)
- Testing
- Jacobson's PMRT
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Breast Cancer, Fatigue
Using Pranayama and Deep Breathing Exercises to Reduce Cancer-Related Fatigue and Insomnia During Radiotherapy
The study aims to evaluate the effectiveness of pranayama and deep breathing exercise in reducing fatigue and insomnia in patients receiving radiotherapy due to breast cancer.
- Conditions
- Breast Cancer, Fatigue, Insomnia
- Trial name
- NCT04441827
- Testing
- breathing exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Cancer-Related Condition
Quantifying Fatigue in Cancer Patients Using Smart Bracelet Devices
This project expects to enroll 60 cancer patients, 60 healthy people and their subjective-objective measurements on fatigue, stress, and total steps will be validated so that the information can be used in further care and…
- Trial name
- NCT04300842
- Testing
- smart bracelet
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Cancer Related Fatigue, Fatigue Syndrome, Chronic
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue (CFS/ME)
Research for Pathophysiology of Cancer Related Fatigue (CRF) and Chronic Fatigue Syndrome (CFS/ME) by Lipidomics, Metabolomics, Intestinal and Peritoneal Microbiome Analysis and Exome Analysis and Investigation of a Possible…
- Trial name
- IMPROFA (NCT03773003)
- Testing
- Probiotics
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universität des Saarlandes