Clinical trials: Cancer Gi
Gastrointestinal Cancer
Endoscopic Nebulizing Device for Surgical Haemostatic-sealant Glubran® 2 Usability Trial in EMR and ESD
The aim of this single-center study is to evaluate the feasibility of the technique, usability and safety of the device ENDONEB.
- Trial name
- NCT06588881
- Testing
- nebulized application of the haemostatic surgical sealant after gastrointestinal endoscopic resection
- Where
- Italy
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- GEM SRL
Cancer, Gastrointestinal Cancer
Long-term Cancer Risk in the Randomised Oslo Diet and Antismoking Study
This study examines the effect of a five-year multifactorial lifestyle intervention in the Oslo diet and antismoking study on long-term cancer risk.
- Conditions
- Cancer, Gastrointestinal Cancer, Lung Cancer, Urinary Tract Cancer
- Trial name
- NCT03410641
- Testing
- Diet and antismoking advice
- Volunteers
- 1,216 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
DPYD Gene Mutation, Gastrointestinal Cancer
Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines
5-fluorouracil and capecitabine, sometimes called 5-FU, fluoropyrimidines, or Xeloda are a type of chemotherapy. Many people have side effects from these drugs like nausea, diarrhea, or blood problems.
- Conditions
- DPYD Gene Mutation, Gastrointestinal Cancer, Health Care Seeking Behavior
- Trial name
- DPYD Nudges (NCT06559462)
- Testing
- Focus Group, Discrete Choice
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Gastrointestinal Cancer, Gastrointestinal Disease
Advancing Nursing Practices in Hospital Oncology Care
The purpose of this study is to find out if a new training program for nurses called PACT (Partnership, Assessment, Care, and Transition) will be effective and relevant in helping nurses gain the skills needed to provide…
- Conditions
- Gastrointestinal Cancer, Gastrointestinal Disease, Nurse's Role
- Trial name
- NCT05053191
- Testing
- Partnership, Assessment, Care and Transition training intervention
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Memorial Sloan Kettering Cancer Center
Irritable Bowel Syndrome, Colitis, Ulcerative
Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders
This clinical trial hypothesize that Gut Microbiota (bacteria, viruses, fungi)play a major role in the occurrence and progression of many chronic gastrointestinal diseases like Irritable Bowel Syndrome, Inflammatory Bowel…
- Conditions
- Irritable Bowel Syndrome, Colitis, Ulcerative, Crohn Disease, Colonic Neoplasms
- Trial name
- NCT01099111
- Where
- Saudi Arabia
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- King Fahad Medical City
Amyotrophic Lateral Sclerosis, GI Cancer
Trial of Ascertaining Individual Preferences for Loved One's Role in End-of-Life
Specific Aims and Hypotheses: Aim 1: To test the effect of the "Trial of Ascertaining Individual preferences for Loved Ones' Role in End-of-life Decisions" (TAILORED) Intervention on family decision-making self-efficacy at 8…
- Conditions
- Amyotrophic Lateral Sclerosis, GI Cancer, Pancreatic Cancer
- Trial name
- NCT01160367
- Testing
- TAILORED Patient Family Decision Making, standard of care
- Where
- United States
- Volunteers
- 431 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Insomnia
Feasibility and Acceptability Study of My Sleep Our Sleep (MSOS) Program
The purpose of this study is to test feasibility and acceptability of a psycho-behavioral intervention on sleep in cancer patients and their partners.
- Trial name
- NCT04712604
- Testing
- My Sleep Our Sleep (MSOS) Program
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cachexia
The Investigation of the Mechanism of Cachexia Occurrence for Patients With Gastrointestinal Cancer
The study is going to recruit patients with gastrointestinal cancer, collect clinical data and peripheral blood sample and possible fat samples.
- Trial name
- NCT04594863
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Cancer Esophagus, Pancreatic Cancer
Effect of Chewing Gum on Postoperative Bowel Function Following Upper GI Tract Cancer Surgery
Every patient undergoing surgery in the abdomen will experience temporary paralysis of bowel function. This study evaluates whether chewing gum can reduce the bowel paralysis after surgery in patients undergoing either esophageal…
- Trial name
- NCT02260128
- Testing
- Chewing gum
- Where
- Denmark
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Michael Bau Mortensen
Colorectal Neoplasms, Intestinal Neoplasms
Usefulness of GI-GENIUS in FIT-based Colorectal Cancer Screening Program.
Deep learning technology has an increasing role in medical image applications and, recently, an artificial intelligence device has been developed and commercialized by Medtronic for identification of polyps during colonoscopy…
- Conditions
- Colorectal Neoplasms, Intestinal Neoplasms, Gastrointestinal Neoplasms, Colonic Polyp
- Trial name
- CADILLAC (NCT04673136)
- Testing
- GI-GENIUS Medtronic, Colonoscopy
- Where
- 6 sites in Spain
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Asociación Española de Gastroenterología
Healthy Adults
Phase 1A Study of the Safety of KSP/QRH Dimer
To evaluate the safety of orally administered KSP-QRH-E3-IRDye800 (Peptide 919288G), a topically administered Li-Cor IRDye800CW labeled heptapeptide dimer (KSP/QRH Dimer) specific for human epithelial growth factor receptor 2…
- Trial name
- NCT03643068
- Testing
- KSP-QRH-E3-IRDye800 (Peptide 919288G), 0.6 mg, KSP-QRH-E3-IRDye800 (Peptide 919288G), 1.8 mg
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Gastrointestinal Stromal Tumors
Symptom Inventory for Gastrointestinal Stromal Tumors
The goal of this research study is to better understand the symptoms experienced by patients with GIST. There are 3 parts to this study.
- Trial name
- NCT01178307
- Testing
- Questionnaires, Interview, MDASI-GIST Questionnaire
- Where
- United States
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Neuroendocrine Carcinoma of Pancreas, Carcinoid
Molecular-Guided Surgery for Pancreatic and GI Neuroendocrine Cancers
The purpose of this study is to see if the use of 68Gallium- positron emission tomography and computer tomography (PET/CT) scans along with NETSPOT® (Advanced Accelerator Applications USA, Inc.) can better define the localization…
- Trial name
- NCT03623984
- Testing
- Gallium Dotatate
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gastrointestinal Cancer, Head and Neck Cancer
Microvascular Function in Patients Undergoing 5-Fluorouracil Chemotherapy
The primary aim of this study is to investigate potential differences in vascular function between patients receiving 5-Fluorouracil (5-FU) chemotherapy, patients receiving chemotherapies other than 5-FU, cancer survivors who…
- Conditions
- Gastrointestinal Cancer, Head and Neck Cancer, Breast Cancer, Chemotherapy Effect
- Trial name
- NCT04042298
- Testing
- Arterial blood pressure, Skin microcirculatory blood flow, Brachial artery blood flow
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Kansas State University
Stage IV Gastrointestinal Cancer, Advanced Gynecological Cancer
The Mediating Effects of Decentering on Self-Management of Stress and End of Life Planning
Caregivers of persons with cancer may face many challenges as they support and care for a person receiving treatment. Sometimes having to help make treatment decisions for a patient can cause distress for caregivers.
- Trial name
- NCT02842047
- Testing
- Stop, Breathe & Think™, End of Life Planning Videos, Caregiver wellness videos
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Case Comprehensive Cancer Center
Gastrointestinal Cancer
Study of 18F-FAPI Applied to Gastrointestinal Cancer
Comparison of tumor volume, number, and SUVmax of different primary foci (gastric, duodenal, and colon cancer), lymph node metastases (neck and supraclavicular, mediastinal, abdominal, and pelvic), and distant metastases (brain…
- Trial name
- NCT05788874
- Testing
- 18F-FAPI and 18F-FDG PET/CT
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Gastrointestinal Cancer
Dyadic Sleep Study
The purpose of this study is to learn about sleep behaviors and test different ways to help patients with cancer and caregiver partners.
- Trial name
- NCT06569693
- Testing
- My Sleep Our Sleep (MSOS) Program, Brief Behavioral Treatment for Insomnia (BBTI)
- Where
- 2 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Miami
Breast Carcinoma, Malignant Digestive System Neoplasm
Studying the Workflow of the American College of Surgeons Geriatric Surgery Program to Improve Clinical Outcomes in Older Adults Undergoing Surgery at the James Cancer Hospital
This study examines how the American College of Surgeons Geriatric Surgery Verification Program, also called the ACS GSV Program, is implemented at the James Cancer Hospital.
- Conditions
- Breast Carcinoma, Malignant Digestive System Neoplasm, Malignant Female Reproductive System Neoplasm, Malignant Genitourinary System Neoplasm
- Trial name
- NCT07606287
- Testing
- Serious Illness Conversation Program training, ACS Geriatric Surgery Verification Program Implementation
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Healthy, Gastrointestinal Cancer
Dietary Nitrate and Nitrite Intake and Phosphate Biomarkers and Risk of Chronic Diseases
Nitrate, nitrite, and phosphate (NO3, NO2, P) are at all age stages ubiquitous in our everyday foods, including naturally occurring and as food additives, and in our drinking water.
- Conditions
- Healthy, Gastrointestinal Cancer, Cardiovascular Diseases, Chronic Obstructive Airway Disease
- Trial name
- NCT07746310
- Where
- Sweden
- Volunteers
- 86,000 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Digestive Cancer, Gynecological Cancer
Analysis of Chronic Neuropathic Pain Markers in Patients Treated With Oxaliplatin
The role of oxidative stress in the development of oxaliplatin-induced peripheral neuropathy has been previously described in mice and in neuronal cell cultures (Massicot 2013); clinical manifestations and pathophysiological…
- Trial name
- LIPIDOXA (NCT02169908)
- Testing
- Thermotest, von Frey hairs
- Where
- France
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Fondation Hôpital Saint-Joseph