Clinical trials: Cancer, app or software or digital or wearable or device or sensor
Breast Cancer, Genitourinary Syndrome of Menopause
CO2 Laser Therapy for the Treatment of GSM in Patients With Breast Cancer
Given the need for an effective, non-hormonal treatment for Genitourinary syndrome of menopause GSM) symptoms in breast cancer survivors, the reported efficacy of fractional CO2 laser as such a treatment in retrospective studies…
- Trial name
- NCT04517370
- Testing
- Fractional/Pixel CO2 laser
- Where
- Israel
- Volunteers
- 36 people
- Sponsor
- Hadassah Medical Organization
Congenital Central Hypoventilation Syndrome, Congenital Central Hypoventilation
Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)
Congenital central hypoventilation syndrome (CCHS) is a rare disorder of autonomic and respiratory regulation that frequently alters oxygen delivery to the brain.
- Conditions
- Congenital Central Hypoventilation Syndrome, Congenital Central Hypoventilation, CCHS, CCHS With Hirschsprung Disease
- Trial name
- NCT03568669
- Testing
- NIH Toolbox Cognition Battery
- Where
- 4 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Ilya Khaytin
Pancreas Cancer, Cancer of the Pancreas
Stereotactic Body Radiotherapy and Focal Adhesion Kinase Inhibitor in Advanced Pancreas Adenocarcinoma
Patients with advanced pancreas adenocarcinoma will be randomized on a 6:1 basis to receive standard of care chemotherapy followed by adaptive stereotactic body radiotherapy (SBRT) with concurrent and adjuvant FAK inhibitor…
- Conditions
- Pancreas Cancer, Cancer of the Pancreas, Pancreas Adenocarcinoma
- Trial name
- NCT04331041
- Testing
- Adaptive stereotactic body radiation therapy, Defactinib, Tumor biopsy
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Washington University School of Medicine
Breast Cancer, Carcinoma in Situ
Handheld Ultrasound Device to Triage Women With a Positive Clinical Breast Examination by Trained Non-radiologists
Cross sectional study to evaluate estimate accuracy of portable ultrasound device in correctly differentiating the benign breast lesions from the malignant ones in the women referred with a positive Clinical breast examination…
- Trial name
- PUD (NCT06056843)
- Testing
- Triage of clinical breast examination positive women using handheld ultrasound by non-radiologists.
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Agency for Research on Cancer
Cancer, Polyp
Compression Anastomosis Using the Compression Anastomotic Ring-locking Procedure (CARP)
The intestinal ends must be rejoined after colonic resection. Conventional methods include sutured and stapled anastomoses, which is associated with 3-6% leakage after colonic surgery.
- Trial name
- NCT01451008
- Testing
- Compression anastomotic ring-locking procedure (CARP)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Region Skane
Prostate Cancer
Focal Laser Ablation of Prostate Cancer
The primary objective of this study is to evaluate the safety and feasibility of Magnetic-Resonance(MR)-ultrasound image fusion-guided transrectal-based focal laser ablation (FLA) of prostate cancer using the Orion System, an…
- Trial name
- NCT04305925
- Testing
- Focal Laser Ablation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer, Screening
Artificial Intelligence in Breast Cancer Screening Programs
The use of artificial intelligence software in breast screening (Transpara®) makes it possible to identify studies with a very low probability of cancer.
- Trial name
- AITIC (NCT04949776)
- Testing
- Mammograms
- Where
- Spain
- Volunteers
- 31,301 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Pain
Pilot Study of Transcranial Stimulation (tDCS)to Relieve Neuropathic Pain in Cancer Patients
This is a pilot study designed to collect preliminary data on safety and efficacy of transcranial direct current stimulation (tDCS) to relieve pain in cancer patients who developed neuropathic pain in the affected area after a…
- Trial name
- NCT01948050
- Testing
- non-invasive transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Medical Center
High Risk Prostate Cancer
Novel Imaging in Staging of Primary Prostate Cancer
Prostate cancer (PC) is the most common cancer among men and one quarter of diagnosed PC are metastatic at the time of diagnosis.
- Trial name
- PROSTAGE (NCT03537391)
- Testing
- Whole body contrast enhanced computer tomography, 99mTC-HMDP planar bone scintigraphy (BS), 99mTc-HMDP single photon emission computer tomography/computer tomography
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Turku University Hospital
Prostate Disease, Elevated Prostate Specific Antigen
MR/TRUS Fusion Guided Prostate Biopsy - An Improved Way to Detect and Quantify Prostate Cancer
This research study is designed to determine if targeted Magnetic Resonance Imaging (MRI) Ultrasound (US) fusion biopsy is better than the standard of care ultrasound guided biopsy alone in diagnosing subjects with clinically…
- Conditions
- Prostate Disease, Elevated Prostate Specific Antigen, Family History of Prostate Cancer, Positive Digital Rectal Exam
- Trial name
- NCT04599218
- Testing
- Prostate Biopsy, MR US Fusion Guided Prostate Biopsy, MR/TRUS Fusion Guided Prostate Biopsy
- Where
- 3 sites in United States
- Volunteers
- 1,586 people
- Sponsor
- Ardeshir Rastinehad
Non-Small Cell Lung Cancer
Adaptive Radiotherapy in Locally Advanced Non-Small Cell Lung Cancer (LARTIA Trial)
Anatomical change of tumor during radiotherapy contributes to target missing. However, in the case of tumor shrinkage, adaptation of volume could result in an increased incidence of recurrence in the area of target reduction.
- Trial name
- LARTIA (NCT03583723)
- Testing
- Radiotherapy Group
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Campus Bio-Medico University
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Exercise During Chemotherapy in Older Women With Stage I-III Breast Cancer
This clinical trial evaluates the feasibility of exercise during chemotherapy in older women with stage I-III breast cancer. Previous studies have reported that exercise may reduce the chemotherapy-toxicity risk.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- NCT05025059
- Testing
- Discussion, Exercise Intervention, Informational Intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Cancer of Prostate
Dynamic Focusing Evaluation for Prostate Cancer Treatment
Define the best acoustic parameters for the dynamic focusing HIFU transducer in the treatment of localized Prostate Cancer.
- Trial name
- FOC/DYN (NCT03632980)
- Testing
- "Ablatherm Foc/Dyn" or "Focal One" HIFU treatment
- Where
- France
- Volunteers
- 180 people
- Sponsor
- EDAP TMS S.A.
Breast Cancer
The Immersive Experience of Virtual Reality During Chemotherapy in Patients With Early Breast and Gynecological Cancers: the Patient's Dream Study
"Patient's dream" study is a two-arm randomized controlled trial that will be conducted at Regina Elena National Cancer Institute, IRCCS (Rome), from April 2019 to January 2020.
- Trial name
- NCT05234996
- Testing
- 3 Virtual Reality headset (VR Headset),
- Where
- Italy
- Volunteers
- 44 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Cancer Female
Biofeedback Training on Shoulder Muscles Strength Post Mastectomy
PURPOSE:The purpose of the study is to evaluate the effect of biofeedback on shoulder muscles strength post mastectomy. BACKGROUND: The most common complications following mastectomy are pain, ipsilateral lymphedema of the upper…
- Trial name
- NCT06226688
- Testing
- Biofeedback device and other group control group, Control group
- Where
- 2 sites in Egypt
- Volunteers
- 54 people
- Sponsor
- Cairo University
Pancreatic Cancer, Pancreatic Neoplasms
Wearable-Supported Prehabilitation and Rehabilitation for Patients Undergoing Surgery for Pancreatic Cancer
The goal of this clinical trial is to evaluate whether a wearable-enabled prehabilitation and rehabilitation pathway can improve recovery and post-operative outcomes in adults undergoing surgery for pancreatic cancer or related…
- Conditions
- Pancreatic Cancer, Pancreatic Neoplasms, Periampullary Carcinoma, Pancreatic Surgery
- Trial name
- POWR-PaC (NCT07772258)
- Testing
- Corsano CardioWatch, Prehab4Cancer Programme
- Volunteers
- 120 people
- Sponsor
- Manchester University NHS Foundation Trust
Meningitis, Encephalitis
The Effectiveness and Safety of Human Lumbar Puncture Assist Device (LPat)
The purpose of this study is to proof and investigate the effectiveness and safety of the invented device named "Human Lumbar Puncture Assist Device (LPat)" as an assist tool to be utilized to improve the success rate of…
- Conditions
- Meningitis, Encephalitis, Guillain-Barré, Subarachnoid Hemorrhage
- Trial name
- LPat (NCT03710278)
- Testing
- LPat Device
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Spartanburg Regional Healthcare System
Melanoma
War on Melanoma™ Public Health & Education Campaign
This trial studies how well a health educational campaign works in increasing early detection of melanoma in Oregon. The health educational campaign may provide information to help people learn about the early signs of melanoma.
- Trial name
- NCT04611568
- Testing
- Educational Intervention, Health Education, Media Campaign
- Where
- United States
- Volunteers
- 75,000 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Paralytic Ileus, Nausea
The Impact of Preoperative Bowel Exercise on Postoperative Bowel Functions in Gynecologic Malignancies
Gastrointestinal dysfunction is a common complication after abdominal gynecologic oncology surgery. There are numerous studies in the literature addressing the management of bowel function in the postoperative period.
- Conditions
- Paralytic Ileus, Nausea, Defecation Disorder
- Trial name
- IPBEPOBF (NCT06113718)
- Testing
- Abdominal Exercise (digital rectal stimulation, abdominal massage)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Tepecik Training and Research Hospital
Lung Nodules, Lung Cancer (Diagnosis)
Robotic-Assisted Navigation for Lung Nodule Localization: A Non-Inferiority Study
This study compares robotic-assisted navigation and manual CT-guided needle localization for lung nodules under 20 mm. It aims to evaluate localization success, procedure duration, CT scans, and complication rates.
- Conditions
- Lung Nodules, Lung Cancer (Diagnosis), Robotic-Assisted Navigation System
- Trial name
- NCT07055997
- Testing
- Robotic-assisted needle localization, Manual needle localization
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
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