Clinical trials: Calculi, Urinary
Urinary System Stones, Pain
Ultrasound-Guided Erector Spinae Plan Block in Patients Undergoing ESWL
Extracorporeal shock wave lithotripsy (ESWL) is widely used in the treatment of urinary tract stones and is generally applied to outpatients.
- Trial name
- NCT04213924
- Testing
- Bupivacaine HCl 0.5 % in 10 ml and 2 % lidocaine in 10 ml, 5 % Lidocaine Topical Gel and 800 mg ibuprofen intravenously
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Ataturk University
Kidney Calculi
ShockPulse-SE vs. Trilogy Trial: Comparing the Performance of Two Intracorporeal Lithotripters for Removal of Large Renal Calculi
The purpose of this study is to measure how well two different devices work to break up and remove kidney stones. We are comparing a newer device to an older one to see which one is faster at breaking up kidney stones.
- Trial name
- NCT03959683
- Testing
- Trilogy Lithotrite, The ShockPulse-SE Lithotripsy System
- Where
- 4 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Indiana University
Urolithiasis, Kidney Stones
Pain Control During ESWL Using Non-Opioid Analgesics
This prospective randomized controlled trial aims to compare the analgesic efficacy of three non-opioid analgesics (ibuprofen, paracetamol, and tenoxicam) during extracorporeal shock wave lithotripsy (ESWL).
- Conditions
- Urolithiasis, Kidney Stones, Ureteral Stones
- Trial name
- ESWL-PAIN (NCT07512297)
- Testing
- Ibuprofen (Brufen®), Paracetamol (drug), Tenoxicam
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people
- Sponsor
- University of Gaziantep
Kidney Stone, Kidney Calculi
Outcomes of Using FANS With FURS in TTT of Lower Calyceal Stones.
The aim of this study is to evaluate and assess the outcomes of flexible ureteroscopy (FURS) with flexible and navigable suction UAS (FANS) in the treatment of lower calyceal stones.
- Trial name
- NCT07238803
- Testing
- flexible and navigable suction sheath with flexible ureteroscopy
- Where
- Egypt
- Volunteers
- 33 people
- Sponsor
- Zagazig University
Ureteral Calculi, Renal Calculi
Intraureteral Lidocaine for Post-Ureteroscopy Pain
Ureteroscopy (URS) is minimally invasive procedure for management of renal stones. URS is often involves concomitant of an indwelling ureteral stents.
- Trial name
- NCT01450566
- Testing
- Lidocaine, Saline
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Queen's University
Kidney Stone, Normal Controls
Oxalate and Citrate
This is a single-center study that aims to earn more about how two different compounds found in food, oxalate and citrate, may affect a person's chances of forming kidney stones.
- Trial name
- NCT05334979
- Testing
- Kidney stones Normal controls Consuming a special drink (sodium oxalate) during an all day visit to the University of Chicago research clinic
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Kidney Stone, Kidney Calculi
Evaluation of Infection in Obstructing Urolithiasis
Obstructing urolithiasis can be life-threatening in the setting of urinary tract infection. The purpose of this study is to identify and validate risk factors and markers for the presence of infection and development of sepsis…
- Conditions
- Kidney Stone, Kidney Calculi, Urinary Tract Obstruction, Infection
- Trial name
- eIOU (NCT04332861)
- Testing
- Initial clinical and laboratory evaluation
- Where
- 2 sites in United States
- Volunteers
- 477 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stone
Effect of Tamsulosin on Stone Expulsion and Pain Resolution in ED Patients With Ureterolithiasis
Tamsulosin (Flowmax)is approved by the FDA for the treatment for enlarged prostate. Several studies regarding the use of Tamsulosin for the treatment of lower kidney stones have been carried out in the non-Emergency Department…
- Trial name
- Flowmax (NCT00762424)
- Testing
- Flowmax
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- WellSpan Health
Kidney Stones
Laser Versus Ultrasonic Lithotripsy in Percutaneous Nephrolithotomy for Staghorn Stones
This study will be conducted to compare the results of Laser and ultrasonic lithotripsy in disintegration of staghorn stones during percutaneous nephrolithotomy.
- Trial name
- NCT01922414
- Testing
- Laser, Ultrasonic
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansoura University
Kidney Calculi, Nephrolithiasis
Supine vs. Prone PCNL for Large Renal Stones: A Randomized Trial in Yemen.
The goal of this clinical trial is to compare the safety, cost-effectiveness, and patient recovery of two different surgical positions for percutaneous nephrolithotomy (PCNL) in adults aged 18 to 70 years who have kidney stones…
- Trial name
- NCT07627503
- Testing
- Supine Percutaneous Nephrolithotomy (PCNL), Prone Percutaneous Nephrolithotomy (PCNL)
- Where
- Yemen
- Volunteers
- 140 people
- Sponsor
- Sana'a University
Upper Urinary Tract Stones
Role of Nephrolithometric Scoring Systems in Prediction of PCNL Outcomes in Adult
Prospective study is to compare between different nephrolithometric scoring systems in prediction of PCNL outcomes in terms of efficacy , success rate and safety in Adult patients with UUT stones unilateral or bilateral, single…
- Trial name
- NCT04158570
- Testing
- Percutaneous Nephrolithotomy
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Assiut University
Kidney Stones
Night Time Use of Thiazide Diuretics for Improved Reduction in Stone Risk in Stone Formers With Elevated Urine Calcium
Thiazide diuretics will be more effective in lowering urine calcium excretion if taken at night as compared to the daytime. It will therefore be more effective in reducing kidney stone recurrence in nephrolithiasis patients with…
- Trial name
- NCT02711670
- Testing
- chlorthalidone, Hydrochlorothiazide
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- VA New York Harbor Healthcare System
Management of Obstructed Infected Kidney
Ureteral Stent Versus Percutaneous Nephrostomy in Acutely Obstructed Infected Kidney
Non-malignant causes of ureter obstruction can be intrinsic such as stone disease, ureter stricture or congenital ureteropelvic junction obstruction, or extrinsic such as idiopathic retro peritoneal fibrosis.
- Trial name
- NCT03498794
- Testing
- Ureteral stent
- Where
- Egypt
- Volunteers
- 2 people
- Sponsor
- Assiut University
Stone;Renal, Stone, Urinary
Comparison Between Two Methods for Renal Stone Treatment Mini Percutaneous Nephrolithotomy and Flexible Ureteroscopy With Suction Sheath
This study aims to compare the efficacy and safety of two modern, minimally invasive surgical techniques for the removal of kidney stones: Mini-Percutaneous Nephrolithotomy (Mini-PCNL) and Flexible Ureteroscopy (FURS) with…
- Conditions
- Stone;Renal, Stone, Urinary, Stone, Kidney, Stone Clearance
- Trial name
- mini-PCNL/FANS (NCT07306819)
- Testing
- mini-percutaneous nephrolithotomy, Flexible Uerteroscopy with Tip-Bendable Suction Sheath
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Kidney Calculi, Ureteral Calculi
Alfuzosin Hydrochloride to Promote Passage of Distal Ureteral Calculi
This study will assess improvement in the percentage of spontaneous stone passage for distal ureteral calculi for alfuzosin compared to placebo, decrease of pain and narcotic/analgesic use associated with stone passage, decrease…
- Conditions
- Kidney Calculi, Ureteral Calculi, Colic
- Trial name
- NCT00177086
- Testing
- Alfuzosin Hydrochloride
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- University of Minnesota
Kidney Stone
Research on Early Warning and Diagnosis & Treatment Pathway for Micro Kidney Stones
Exploring abnormal metabolism in kidney stone patients and developing drugs for kidney stone treatment and their mechanisms of action.
- Trial name
- NCT07350369
- Testing
- Detect the levels of metabolites in blood and urine
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Ureter Stone, Renal Stone
Duration Between Drainage and Ureteroscopic Lithotripsy
This study will be conducted to compare early (seven days) versus delayed (14-21 days) definitive ureteroscopic lithotripsy after initial drainage for obstructing ureteral or renal stones associated with infection.
- Conditions
- Ureter Stone, Renal Stone, Ureteric Obstruction
- Trial name
- NCT06101563
- Testing
- Early ureteroscopy, Delayed Ureteroscopy
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Mansoura University
Urolithiasis of Bladder
TFL vs MOSES Holmium Laser in the En-bloc Resection of Bladder Tumors
The goal of this randomized clinical trial is to determine if there is difference in pathological and clinical outcomes between MOSES and TFL in the transurethral laser enucleation of bladder tumors.
- Trial name
- NCT06373419
- Testing
- TFL, MOSES holmium laser
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Thunder Bay Regional Health Research Institute
Renal Calculi
A Pilot Study Assessing The Feasibility Of Outpatient Tubeless Percutaneous Nephrolithotomy (PCNL)
Outpatient tubeless Percutaneous nephrolithotomy (PCNL) could potentially improve patient care and result in significant cost savings for our hospital each year.
- Trial name
- NCT01437904
- Testing
- Outpatient Recovery, In hospital recovery
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Queen's University
Kidney Calculi, Nephrolithiasis
Nebulized Glubran 2-Assisted Tubeless PCNL Versus Conventional PCNL
This prospective randomized controlled study will compare two techniques used after percutaneous nephrolithotomy, a procedure for removing kidney stones.
- Trial name
- NCT07749807
- Testing
- Nebulized Glubran 2-Assisted Tubeless PCNL, Conventional PCNL With Nephrostomy Tube
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Benha University