Clinical trials: Calcium Phosphates
Dental Caries
Evaluation of a New Bioactive Material Versus a Fluoride-Releasing Hybrid Restorative Material in Cervical Lesions
This study will be conducted to evaluate and compare the clinical performance of fluoride, calcium, and phosphate-releasing new bioactive material versus a fluoride-releasing hybrid restorative material in cervical lesions for…
- Trial name
- NCT05149209
- Testing
- cervical restoration
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve
Vitamin D Influence on Oocyte Donation
Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.
- Conditions
- Disorder of Phosphate, Calcium and Vitamin D Metabolism, Female Infertility Due to Diminished Ovarian Reserve, Hormonal Requirement, Reproductive Disorder
- Trial name
- NCT02341365
- Testing
- vitamin D,AMH, AFC, reproductive outcome egg recipients
- Volunteers
- 269 people
- Sponsor
- IVI Madrid
Postoperative Pain
Evaluation of the Effectiveness of Calcium Phosphate Containing Desensitizer on Postoperative Sensitivity
In this randomized clinical study, we aim to evaluate the effects of Teethmate Desensitizer on postoperative sensitivity when applied underneath the composite restoration by comparing it with the negative control group.
- Trial name
- NCT04540835
- Testing
- Teethmate Desensitizer (Kuraray)
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Baskent University
Infertility, Female
Plasma Concentrations of Calcium, Phosphate, FGF23, Klotho, 25 (OH) D3 and 1,25 (OH) 2D3 from Patients Who Wants to Have Children
1,25-dihydroxy-vitamin D3 (1,25 (OH) 2D3) or calcitriol regulates plasma calcium and phosphate concentrations in the blood by stimulating intestinal absorption and renal reabsorption of calcium and phosphate.
- Trial name
- NCT03173235
- Testing
- Plasma level of vitamin D
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Hemodialysis, Hyperphosphatemia
Long Term Evaluation of Sevelamer HCl vs. Calcium-based Phosphate Binder in the Treatment of Hyperphosphatemia in Hemodialysis Patients
The study is designed to compare sevelamer vs. calcium-based phosphate binder in hemodialysis patients to achieve full-scale of medical care, including reduction of atherosclerotic risk factors, reduction of vascular access…
- Conditions
- Hemodialysis, Hyperphosphatemia, Cardiovascular Events
- Trial name
- NCT01755078
- Testing
- Sevelamer HCl, Calcium-based phosphate binder
- Volunteers
- 166 people
- Sponsor
- Chugai Pharma Taiwan
Fractures, Enophthalmos
Polycaprolactone / Tricalcium Phosphate (PCL/TCP) v Titanium Orbital Implant : Randomised Trial
Hypothesis: Polycaprolactone / Tricalcium Phosphate Orbital (PCL / TCP) Implant is as effective in the reconstruction of the Orbital walls as Titanium Mesh implant.
- Conditions
- Fractures, Enophthalmos, Diplopia
- Trial name
- PCL/TCP (NCT01119144)
- Testing
- Polycaprolactone / Tri-Calcium Phosphate, Titanium Mesh
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- National University Hospital, Singapore
Healthy
Comparison of Three Calcium Supplements
The study was conducted to investigate the metabolic effects of three different calcium compounds in healthy adults.
- Trial name
- NCT03286673
- Testing
- calcium phosphate, Tricalcium Phosphate, Calcium carbonate
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Jena
Cranial Defect
Comparison of Calcium Phosphate Cement With Patient-specific Implants for Cranial Reconstruction
Background Cranial reconstruction after monocortical bonegraft harvesting remains a clinical challenge for the maxillofacial surgeon. At present, there is no gold standard technique advised.
- Trial name
- CRAN-PSI (NCT03841643)
- Testing
- patient-specific implant, cement
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- AZ Sint-Jan AV
Healthy Volunteers
Effects of Soluble Phosphate in Humans
The study was conducted to investigate the effect of soluble phosphate in combination with different calcium doses on calcium and phosphorus metabolism and further physiological parameters in healthy subjects.
- Trial name
- NCT02095392
- Testing
- P1000/Ca0, P1000/Ca500, P1000/Ca1000
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Jena
Calcium Phosphate Kidney Stones
Methionine for CaPhos Stone
Some kidney stones including calcium phosphate and struvite stones form in vary alkaline urine (high pH). Currently available medication for stone prevention, namely citrate supplementation, can lead to even higher pH levels and…
- Trial name
- NCT07465367
- Testing
- L-Methionine
- Volunteers
- 15 people
- Sponsor
- Ryan L Steinberg
End Stage Renal Disease
Effect of Lanthanum Carbonate in Patients Previously Treated With Calcium-based Phosphate Binder Therapy
To assess the percentage of patients on lanthanum carbonate, that achieve Kidney Disease Outcome Quality Initiative (KDOQI) guideline suggested values for serum phosphorous in patients previously treated with calcium-based…
- Trial name
- NCT01130831
- Testing
- Lanthanum carbonate
- Where
- 31 sites in Germany
- Volunteers
- 66 people
- Sponsor
- Shire
Kidney Stones, Urolithiasis, Hypocitraturia, Nephrolithiasis
Sodium Bicarbonate as an Alternative to Potassium Citrate for Kidney Stones
Kidney stones affect 1 in every 11 people in the US each year. In patients with kidney stones who are prescribed medications for stone management, only 30.2% are adherent to a medication regime and even fewer, only 13.4 % are…
- Trial name
- NCT07408076
- Testing
- Potassium Citrate, Sodium Bicarbonate
- Where
- 6 sites in United States, Canada and 1 more
- Volunteers
- 30 people
- Sponsor
- University of California, Los Angeles
Missing Several Teeth, Minimum of 2 Dental Implants Needed
Soft Tissue Responses Around Nanostructured Calcium-phosphate-coated Implant Abutments on Dental Implants: Histological, Genetic and Clinical Evaluation in Smokers and Non-smokers.
Baseline: Standard preparation of the osteotomy Placement of 2 dental implants On each implant one of both types of healing abutments is placed Suturing Standardized radiography to measure bone-levels at baseline Digital…
- Trial name
- STRANDI (NCT01620918)
- Testing
- normal healing abutment, nano-structured healing abutment
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Ghent
Healthy Men
Calcium Phosphate and Incretins
The study was conducted to investigate the effect of a calcium phosphate supplementation on the secretion of incretins.
- Trial name
- NCT01296997
- Testing
- calcium phosphate
- Where
- Germany
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Jena
Autosomal Dominant Polycystic Kidney Disease
Short-term Effects of an SGLT2 Inhibitor on Divalent Ions in Autosomal Dominant Polycystic Kidney Disease
This study aims to better understand electrolyte handling in patients with autosomal dominant polycystic kidney disease treated with the SGLT2 inhibitor Empagliflozin.
- Trial name
- SIDIA (NCT06435858)
- Testing
- Empagliflozin
- Where
- 2 sites in Switzerland
- Volunteers
- 16 people
- Sponsor
- Cantonal Hospital Graubuenden
Hypersensitivity
Efficacy of Fluoride Varnish Containing Xylitol Coated Calcium Phosphate Versus Conventional Fluoride Varnish in Management of Hypersensitivity of Exposed Root Surfaces in Adult Patients
This clinical trial will be conducted to compare the efficacy of fluoride varnish containing xylitol coated calcium and phosphate or potassium nitrate gel versus conventional fluoride varnish in the management of hypersensitivity…
- Trial name
- NCT04472182
- Testing
- Fluoride varnish with xylitol coated calcium and phosphate
- Where
- Egypt
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Cairo University
Rendu Osler Disease
Calcium-phosphate Complications Induced by IV Iron Supplementation in Patients With Rendu-Osler Disease
Hypophosphatemia induced by treatments with injectable iron is a frequent side effect already reported during marketing. Situations of osteomalacia secondary to these hypophosphatemias are rarer and reported in the form of case…
- Trial name
- OS-LERETRO (NCT05544669)
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Strasbourg, France
Distal Radius Fracture
Comparison of Volar Locking Plate Fixation Alone and Volar Locking Plate Fixation Plus Calcium Phosphate Bone Cement Augmentation for Distal Radius Fractures Patients Aged More Than 65
The incidence of distal radius fracture (DRF) increases with age, and thus, because of improving life expectancies, these fractures are set to become more common.
- Trial name
- NCT01091415
- Testing
- calcium phosphate bone cement injection
- Where
- South Korea
- Volunteers
- 41 people
- Sponsor
- Ewha Womans University
Caries
Modified Atraumatic Restorative Treatment Using CPP ACP
To evaluate the clinical and radiographic success of using Casein Phosphopeptide Amorphous Calcium Phosphate (CPP-ACP) under glass ionomer restorations in atraumatic restorative treatment as a biomimetic approach in pediatric…
- Trial name
- NCT06098911
- Testing
- MI varnish
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Maxillary Sinus Augmentation
Maxillary Sinus Lift With and Without Self-hardening Biphasic Calcium Phosphate.
This study was carried out to compare the outcome of sinus lift without grafting material, versus the use of moldable, self hardening calcium phosphate biomaterials with simultaneous implant placement.
- Trial name
- NCT04214054
- Testing
- Moldable self-hardening biphasic calcium phosphate graft, No graft material placed - Blood Clot only
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly