Clinical trials: Calcium Hydroxide
Apical Periodontitis, Irreversible Pulpitis with Apical Periodontitis
To Measure Post Operative Pain Severity by Using Two Different Intra Canal Medicaments Calcium Hydroxide and Triple Antibiotic Paste in Teeth with Single Roots and Periapical Disease Called Apical Periodontitis
The aim of this study is to compare post operative pain effectiveness between two most commonly available intra canal medicaments that are Triple Antibiotic Paste and Calcium Hydroxide during root canal treatment of single rooted…
- Trial name
- NCT06821763
- Testing
- Calcium Hydroxide Intracanal medication, triple antibiotic paste (TAP)
- Where
- Pakistan
- Volunteers
- 180 people
- Sponsor
- Komal Ashraf Khan
MTA, Calcium Hydroxide
Influence of Temporary Filling Material Composition on the Success Rate of Endodontic Treatments
The aim of this study is through a randomized clinical trial, double blind, splitmouth, evaluate the success rate (contamination rate, periapical lesion relapse and the presence of exudate between the treatment's sessions) of…
- Conditions
- MTA, Calcium Hydroxide, Endodontic Treatment
- Trial name
- NCT03488316
- Testing
- Carie removal, Absolute isolation, Manipulation of the temporary filling material based on Calcium Hydroxide
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- PAULO VINICIUS SOARES
Endodontically Treated Teeth, Calcium Hydroxide
Multiple-Visit RCT in Teeth With SAP: Interappointment Dressing or Not?
The aim of the study is to evaluate the effectiveness of calcium hydroxide as an intracanal medicament in the clinical and radiographic healing of periapical tissues in teeth diagnosed with symptomatic apical periodontitis.
- Trial name
- RCTCa(OH)2 (NCT06447519)
- Testing
- Ca(OH)2 as intracanal medicament
- Where
- Greece
- Volunteers
- 110 people
- Sponsor
- Aristotle University Of Thessaloniki
Reversible Pulpitis
Effectiveness of Biodentine v/s Calcium Hydroxide as Indirect Pulp Capping Materials
This study compares the clinical and radiographic effectiveness of Biodentine and Calcium Hydroxide as indirect pulp capping materials in mature permanent teeth with reversible pulpitis.
- Trial name
- NCT07147036
- Testing
- Biodentine - Indirect Pulp Capping, Calcium Hydroxide - Indirect Pulp Capping
- Where
- Pakistan
- Volunteers
- 76 people
- Sponsor
- Zahoor khan
Chronic Apical Periodontitis
Comparison of the Effects of N-acetylcysteine, Calcium Hydroxide, and Double Antibiotic Paste
This study aimed to evaluate the efficacy of N-acetylcysteine (NAC) used as an intracanal medicament on antibacterial activity, periapical RANKL/OPG ratio, and postoperative pain levels.
- Trial name
- NCT07340944
- Testing
- N Acetyl Cysteine, Calcium Hydroxide (Ca(OH)2), Double Antibiotic Paste
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Drug Effect
Evaluation of Antibacterial Effect of Allium Sativum, Calcium Hydroxide and Their Combination in Infected Mature Teeth
This study was to evaluate and compare garlic extract antibacterial effect when used as an intra-canal medicament in infected mature anterior teeth with calcium hydroxide and a mixture of calcium hydroxide and garlic, using real…
- Trial name
- Garlic (NCT05050071)
- Testing
- Allium Sativum, Polymerase chain reaction
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suez Canal University
Pulpitis - Irreversible, Tooth Decay
Efficacy of PRF and MTA as Compared to Calcium Hydroxide for Pulpotomy in Human Irreversibly Inflamed Permanent Teeth
Of all the various pulpotomy medicaments that have been studied till to date, three agents have been selected for this study to compare their efficacy.
- Trial name
- NCT05266859
- Testing
- Calcium hydroxide, MTA, PRF
- Where
- Pakistan
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Liaquat College of Medicine and Dentistry
Apical Periodontitis
Single And Multiple-visit Endodontic Retreatment Outcome.
This study will compare the outcome of single visit retreatment and multi-visit retreatment in cases of failed root canal treated teeth.
- Trial name
- NCT04390789
- Testing
- Non surgical Single visit Retreatment, Multi visit Retreatment with calcium hydroxide dressing
- Where
- 2 sites in India
- Volunteers
- 90 people
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain
Evaluation of Postoperative Pain and Antimicrobial Efficacy of Selenium Versus Calcium Hydroxide As Intracanal Medication in Mandibular First Molars with Necrotic Pulp and Symptomatic Apical Periodontitis
The main rational behind intracanal medicament is to kill the bacteria inside the root canal and to avert reinfection. In absence of nutrients, the bacteria remains after obturation in root canal may not survive.
- Conditions
- Necrotic Pulp with Symptomatic Apical Periodontitis, Postoperative Dental Pain, Antimicrobial Effect
- Trial name
- NCT06804330
- Testing
- root canal treatment and intracanal medicament
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Periapical Abscess
Comparison of Triple Antibiotic Paste With Combination of Chitosan and Calcium Hydroxide as a Root Canal Disinfectant
Investigators observed the clinical and radiographic healing of periapical lesion using Chitosan mixed with calcium hydroxide and compared it with triple antibiotic paste when used as intracanal medicament in 3months, 6 months…
- Trial name
- NCT04319575
- Testing
- root canal treatment and intracanal medicament
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Dr. D. Y. Patil Dental College & Hospital
Apical Periodontitis
N-acetylcysteine for Root Canal Treatment of Necrotic Teeth With Apical Periodontitis
A randomized controlled trial comparing the postoperative pain intensity, periapical biomarkers level, and periapical healing in patients with necrotic mature teeth and apical periodontitis treated with N-acetylcysteine (NAC), as…
- Trial name
- NAC (NCT07262554)
- Testing
- Calcium hydroxide (Ca(OH)₂), N-Acetylcysteine (NAC)
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alexandria University
Periapical Lesion Healing, Apical Periodontitis
The Effect of Different Intracanal Medicaments on Periapical Lesion Healing
This study is planned to evaluate the effects of two different intracanal medicaments-calcium hydroxide and diclofenac sodium-on periapical healing following endodontic retreatment.
- Trial name
- NCT07237620
- Testing
- Diclofenac sodium
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mustafa Kemal University
Dental Pulp Capping
Clinical and Radiographic Evaluation of Indirect Pulp Capping in Primary and Permanent Teeth With Different Materials
Indirect pulp capping (IPC) is a treatment that preserves pulp's vitality. Several materials have been used for this procedure. The aim of this study is to evaluate the radiographic and clinical outcomes of TheraCal LC (Bisco…
- Trial name
- NCT03606681
- Testing
- Calcium Hydroxide, Mineral Trioxide Aggregate, TheraCal LC
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Pulpitis - Irreversible, Pulp Necroses
Lesion Sterilization Tissue Repair and Conventional Pulpectomy in Primary Molars
The aim of this study was to compare the clinical and radiographic success of conventional root canal treatment and lesion sterilisation tissue repair methods in deciduous molars with necrotic or irreversible pulpitis.
- Conditions
- Pulpitis - Irreversible, Pulp Necroses, Root Canal Infection
- Trial name
- NCT06811636
- Testing
- Lesion sterilization and tissue repair, Conventional pulpectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Intracanal Medication, Bromelain
Effect of Bromelain Versus Calcium Hydroxide as an Intracanal Medication on the Intensity of Postoperative Pain and Bacterial Load Reduction in Necrotic Single Rooted Lower Premolars
the aim of the study is to compare the effect of bromelain vs calcium hydroxide as intracanal medication on intensity of pain and bacterial load in necrotic single lower premolars
- Conditions
- Intracanal Medication, Bromelain, Calcium Hydroxide, Bacterial Load Reduction
- Trial name
- NCT05687760
- Testing
- bromelain, Calcium hydroxide
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Primary Teeth, Pulp Necroses
Treatment of Infected Pulp in Primary Teeth With a Mixture of Calcium Hydroxide and Gingerols
This study was conducted to evaluate Calcium Hydroxide mixed with Gingerols versus Metapex in treatment of primary teeth with infected necrotic pulp
- Conditions
- Primary Teeth, Pulp Necroses, Infected Pulp, Root Canal Treatment
- Trial name
- NCT05181813
- Testing
- Ginge-Cal, Metapex
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Infected Pulp, Root Canal Treatment
Evaluation Of Different Pulpotomy Agents Used For Treatment Of Immature Molars
The management of permanent teeth with incomplete root development with compromised pulpal integrity presents a unique challenge.
- Trial name
- NCT05347160
- Testing
- Biodentine
- Where
- Egypt
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Necrotic Pulp
Evaluation of Pain Relief and Bacterial Reduction After Using Calcium Hydroxide With Mesoporous Silica Nanoparticles as an Intracanal Medicament in Necrotic Mandibular Molars: A Randomized Controlled Clinical Trial
This study compares how well different root canal medications reduce pain and bacteria after treatment of lower molar teeth with necrotic pulp.
- Trial name
- NCT07327996
- Testing
- Calcium Hydroxide Intracanal medication, mesoporous silica nanoparticles paste, Calcium Hydroxide + mesoporous silica nanoparticles
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Apical Periodontitis
2% Chlorhexidine (CHX) vs CaOH2 (CH) Calcium Hydroxide Paste as an Intracanal Medicament
This is a Pilot Phase III single-blind randomized controlled clinical trial in patients, aged 18 years and older, presenting with symptoms of apical periodontitis.
- Trial name
- NCT03700788
- Testing
- Chlorhexidine, Calcium Hydroxide
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Caries, Dental Pulp Exposure
Calcium Hydroxide, Mineral Trioxide Aggregate and Biodentine (Trademark) as Direct Pulp Capping of Permanent Teeth
Background: Dental caries is considered an oral health problem worldwide. In Chile the last national epidemiological study (2007) showed a national prevalence of dental caries in children 6 years (70.3%) and 12 (62.5%).
- Trial name
- NCT02492841
- Testing
- Mineral trioxide aggregate, Calcium hydroxide, Biodentine
- Where
- Chile
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- Universidad de los Andes, Chile