Clinical trials: Caffeine
Healthy Elderly Citizens
The Effect of Caffeine in Elderly Citizens
The study investigated the effect of caffeine on physical performance in healthy citizens aged over 70 years. The main hypothesis was that 6 mg/kg caffeine would improve cycling endurance at 65% of expected maximal heart rate.
- Trial name
- NCT00117520
- Testing
- Caffeine
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Herning Hospital
Dietary Supplement
Influence of the Time of Day in the Effect of Caffeine on Maximal Fat Oxidation During Exercise in Women
Caffeine is a natural stimulant with well-recognized metabolic benefits, however, there is a lack of studies investigating the time-of-day caffeine influence to enhance fat oxidation in women.
- Trial name
- CIRCAF_WOM (NCT05880186)
- Testing
- Acute caffeine supplementation
- Where
- Spain
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Universidad Francisco de Vitoria
Hemodynamics, Caffeine
Improving Cognition With Neurodegradation Countermeasure
The goal of this randomized, placebo-controlled, three-condition, double-blind, within-participants crossover clinical trial is to compare caffeine, TeaCrine plus caffeine, and a placebo condition in ROTC or tactical personnel.
- Conditions
- Hemodynamics, Caffeine, TeaCrine, Cognitive Change
- Trial name
- NCT05715073
- Testing
- TeaCrine and Caffeine, Caffeine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Postoperative Nausea and Vomiting
Caffeine in the Prevention of Post-operative Nausea and Vomiting
The objective of this study is to determine if caffeine 500 mg intravenously is efficacious when added to standard anti-emetic prophylaxis in the prevention of post-operative nausea and vomiting (PONV) in patients undergoing…
- Trial name
- NCT00130026
- Testing
- Caffeine
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Beth Israel Deaconess Medical Center
Respiratory Distress Syndrome
Caffeine Treatment in in the Delivery Room
Background. In recent years, particular attention has been paid to all interventions that could help reduce the need for mechanical ventilation MV and, therefore, the risk of BPD.
- Trial name
- CAFROOM (NCT04044976)
- Testing
- Caffeine Citrate
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- University of Florence
Sports Performance
Effects of L-Tyrosine and Caffeine on Performance in Elite Boxers
Participants will complete six sessions, including one familiarization and baseline session followed by five experimental conditions: control (no supplementation), placebo, L-tyrosine, caffeine, and combined L-tyrosine plus…
- Trial name
- TYCAF-BOX (NCT07530185)
- Testing
- L-Tyrosine, Caffeine, L-tyrosine + Caffeine
- Where
- Turkey (Türkiye)
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Inonu University
Healthy
Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers
In this study the investigators compare three stimulants to each other. The effects of these agents on cognitive performance (eg, attention and memory) and on the brain are being measured.
- Trial name
- MKM (NCT02071615)
- Testing
- Methylphenidate 20 mg tablet given once by mouth, modafinil 200mg tablet given once by mouth, caffein 200mg tablet given once by mouth
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Molecular Imaging
Evaluation of the Effect of Fasting and Exercise on Uptake of Tc-99m Sestamibi in Breast Tissue
The primary objective of this study is to determine if exercise, fasting, or eating prior to the molecular breast imaging study will have an effect on the uptake of the tracer in the breast tissue.
- Trial name
- NCT01944215
- Testing
- Meal, Exercise, Sestamibi
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Asthma
Effects of Caffeine on Methacholine Challenge and Exhaled Nitric Oxide Levels.
To investigate whether or not the ingestion of caffeine with alter airway responsiveness to methacholine and/or change the level of exhaled nitric oxide.
- Trial name
- NCT01057875
- Testing
- caffeine, No caffeine
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- University of Saskatchewan
Caffeine, Cognitive Change
Acute Effects of PLT Health Solutions zümXR Extended-Release Caffeine
This will be a (2 visit) double-blind, randomized, crossover design clinical study to assess the potential benefits of ER-CAFF versus IR-CAFF by assessing its impact on side effect profiles, mood states, alertness, and cognitive…
- Conditions
- Caffeine, Cognitive Change, Mood, Mood Change
- Trial name
- NCT06441695
- Testing
- xumXR extended release caffeine, immediate release caffeine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Caffeine and Resistance Exercise
Reproducibility of Acute Caffeine Effect
Introduction: Various studies have evaluated and verified the ergogenic effect of acute caffeine intake on sports performance, specifically on strength and power performance.
- Trial name
- NCT06606639
- Testing
- Caffeine
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alcala
Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation
A Study on the Impact of a New Canton-Wide First Responder System in Zug, Switzerland, on Survival After Adult Cardiac Arrest-Examining Early Life-Saving Organized Help, Fast Defibrillation, and Improved Outcomes for Out of Hospital Cardiac Arrest
REVIVE Zug: Improving Emergency Response for Out-of-Hospital Cardiac Arrest Out-of-hospital cardiac arrest (OHCA) represents one of the most time-critical medical emergencies, where rapid recognition and immediate intervention…
- Conditions
- Cardiac Arrest (CA), Cardiac Arrest With Successful Resuscitation, Resuscitation, Emergency Medical Services
- Trial name
- REVIVE Zug (NCT07323667)
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Felix Brinkmann
Cognitive Function
Radicle Revive™: A Study Assessing the Impact of Health and Wellness Products on Menopausal-Related Health Issues Associated Health Outcomes and Related Health Outcomes
Radicle Revive™: A randomized, double-blind, placebo-controlled study assessing the impact of health and wellness products on menopausal-related health issues associated health outcomes.
- Trial name
- NCT07548307
- Testing
- Revive Active Product 1
- Where
- United States
- Volunteers
- 990 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Mechanical Ventilation Complication, Caffeine
The Caffeine Therapy in the Fetal to Neonatal Transition
Introduction: The caffeine is used in the treatment for apnea of prematurity and it has several positive effects in the neurodevelopment of preterm babies.
- Conditions
- Mechanical Ventilation Complication, Caffeine, Ventilator Lung; Newborn
- Trial name
- NCT05454332
- Testing
- Early Caffeine administration, Control Group
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
CYP1A2 Polymorphism
Personalized Nutrition Caffeine Intake in Healthy Adults.
Personalized nutrition is one of the most up to date trends in human nutrition and gains much interest of general public and scientists as well.
- Trial name
- NCT04122053
- Testing
- Intervention group with genotype information, Control group without genotype information
- Where
- Poland
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Poznan University of Life Sciences
Sepsis
Digital Alerts for Sepsis: a Qualitative Study
Sepsis is a serious disease, most often caused by a bacterial infection, and can be treated with antibiotics. Identifying patients with sepsis as early as possible means treatment with antibiotics can be started earlier.
- Trial name
- DiAlSQual (NCT05741801)
- Testing
- interviews
- Where
- United Kingdom
- Volunteers
- 39 people
- Sponsor
- University of Oxford
Metabolism, Interaction
-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms
The purpose of this study are: 1. to evaluate the involvement of CYP2D6, CYP3A4 and CYP1A2 (through dextromethorphan and caffeine challenges), and catechol-O-methyltransferase (COMT)in MDMA metabolism 2.
- Trial name
- NCT01447472
- Testing
- MDMA
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Postoperative Dental Pain
A Study to Learn How Well a Single Dose of the Study Treatment Naproxen Sodium and Caffeine Combined in One Tablet (Fixed-dose Combination) Works to Relieve Pain After Dental Surgeries Compared to the Single Ingredients and to Placebo
Researchers are looking for a better way to relieve pain in people, such as after dental surgery. Participants in this study, have had 3 or 4 third molars (cheek teeth) removed and subsequently have moderate to severe tooth pain.
- Trial name
- NCT05485805
- Testing
- Naproxen sodium and caffeine (BAY2880376), Naproxen sodium (Aleve), Caffeine
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Bayer
Caffeine
Effect of Caffeine on Myocardial Oxygenation
The purpose of this study is to investigate the impact of caffeine on myocardial oxygenation and other cardiovascular magnetic resonance parameters in healthy controls.
- Trial name
- Coffee-O2 (NCT04585854)
- Testing
- Caffeine
- Where
- Switzerland
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Critical Care Medicine, Mechanical Ventilation
Evaluating the Clinical Effectiveness of "Endotracheal Tube Position Anomaly Alerting System"
The goal of this clinical trial is to determine whether the Endotracheal Tube Position Anomaly Alerting System (ETPAAS) effectively reduces the duration of endotracheal tube malposition in patients admitted to the intensive care…
- Conditions
- Critical Care Medicine, Mechanical Ventilation, Radiographic Image Interpretation, Computer-Assisted, Alarms
- Trial name
- ETPAAS-1 (NCT06857019)
- Testing
- "Endotracheal Tube Position Anomaly Alerting System"
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital