Clinical trials: CVD
Microvascular Dysfunction, Microvasculature
Palmitic Acid and Human Microvascular Function
The goal of this study is to learn how a supplement Quercetin can affect microvascular function. Participants will: give two blood draws of 5 mL each have a camera placed under the tongue to take pictures of blood vessels have 2…
- Conditions
- Microvascular Dysfunction, Microvasculature, Cardiovascular Diseases, Cardiovascular Diseases (CVD)
- Trial name
- NCT06683534
- Testing
- Quercetin (dietary supplement)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Medical College of Wisconsin
Cardiovascular Diseases (CVD), Cerebro Vascular Disease
Identifying Risk Factors and Predicting Future Health Outcomes for Korean Patients With Heart and Blood Vessel Diseases: A Long-term Follow-up Study
This study aims to establish a comprehensive, long-term clinical registry infrastructure for heart and brain vascular diseases (cardiovascular diseases and stroke) at Samsung Medical Center.
- Trial name
- NCT07393412
- Testing
- Standard Medical Therapy, Revascularization Procedures, Lifestyle Modification
- Where
- South Korea
- Volunteers
- 800,000 people
- Sponsor
- Samsung Medical Center
Cardiovascular Diseases (CVD), Chronic Kidney Disease
Study on Construction of Whole Lifecycle Cohort, Big Data Management and Clinical Prognosis of Cardio-Renal-Metabolic (CKM) Syndrome
This is a single-center observational registry study aiming to establish a structured clinical and multimodal imaging database for cardiovascular-kidney-metabolic (CKM) populations and to support lifecycle follow-up and outcome…
- Conditions
- Cardiovascular Diseases (CVD), Chronic Kidney Disease, Metabolic Diseases, Cardiovascular-kidney-metabolic Syndrome
- Trial name
- CKM-LCBP (NCT07547098)
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
Cardiovascular Diseases (CVD), Preoperative Anxiety
Culturally Tailored Nurse-Led Holistic Spiritual Care Improves Hemodynamic Stability and Well-Being in Cardiac Surgery Patients
This study aims to evaluate the effectiveness of culturally tailored nurse-led holistic spiritual care in improving hemodynamic stability and psychological well-being among patients undergoing preoperative cardiac surgery in…
- Conditions
- Cardiovascular Diseases (CVD), Preoperative Anxiety, Cardiac Surgery
- Trial name
- CARE-Cardiac (NCT07540598)
- Testing
- Culturally Tailored Nurse-Led Holistic Spiritual Care
- Where
- Indonesia
- Volunteers
- 248 people
- Sponsor
- Lincoln University College Malaysia
Cardiovascular Morbidity, Cardiovascular Risk Assesment
A Hospital-Based Registry of Preventive Cardiology Clinics
More research is needed to articulate the most effective ways to use these tools as screening tests in cardiovascular risk assessments and how they ultimately affect CVD mortality and morbidity outcomes.
- Conditions
- Cardiovascular Morbidity, Cardiovascular Risk Assesment, Primary Prevention CVD
- Trial name
- PREVENT-CARD (NCT06503341)
- Testing
- Cardiovascular risk assesment
- Where
- Pakistan
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiovascular Diseases, Pakistan
Cardiovascular Diseases (CVD)
Heart Institute BioRepository (HIBR) for Pediatric Heart Disease
The purpose of this protocol is to redefine the Heart Institute BioRepository (HIBR) to facilitate Investigator-initiated and programmatic basic, translational, clinical and outcomes research.
- Trial name
- HIBR (NCT07478354)
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Cardiovascular Disease (CVD), Chronic Obstructive Pulmonary Disease (COPD)
Towards Personalized Nutrition With SCAPIS2-HOME
The Swedish CardioPulmonary bioImage Study (SCAPIS) is a nationwide, open-access, population-based cohort in Sweden designed to study cardiovascular disease and chronic obstructive pulmonary disease.
- Trial name
- NCT06992921
- Testing
- Dietary intervention
- Where
- 2 sites in Sweden
- Volunteers
- 1,641 people, healthy volunteers welcome
- Sponsor
- Chalmers University of Technology
Depression and CVD
A Patient Activation Approach to Implementing Depression Treatment in Cardiac Patients
This study, which is being conducted as part of a Quality Improvement (QI) Initiative at Columbia University Irving Medical Center, will test whether delivering the iHeart DepCare tool increases real world reach and adoption of…
- Trial name
- iHeart_2 (NCT07390331)
- Testing
- iHeart Depcare tool
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Columbia University
CVD - Cardiovascular Disease
Community Health Worker-Led Intervention to Increase Cardiac Rehabilitation Participation
This study is being done to evaluate whether a program called Heart to Heart, that helps patients make a more informed decision about cardiac rehab (CR), is interesting, acceptable to participants, and whether participants would…
- Trial name
- H2H (NCT06908590)
- Testing
- Education, Providing and Engaging Social Support and Assistance with Health System Navigation
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases (CVD)
TotalCardiology Letters Study
The goal of this study is to see if a theory-based motivational letter can increase attendance at a one-year post-cardiac rehabilitation (CR) appointment in adults who have finished a CR program.
- Trial name
- NCT07430644
- Testing
- Theory-based motivational letter
- Where
- 2 sites in Canada
- Volunteers
- 102 people
- Sponsor
- University of Calgary
Cardiovascular Diseases (CVD)
Preventing Ischemic Heart Disease With mHealth (Mobile Health), Electronic Decision Support and Community Health Workers
This is a cluster-randomized clinical trial (cRCT) designed to assess the effectiveness of a multicomponent strategy linking key aspects of the cardiovascular disease (CVD) care continuum across three provinces in Argentina using…
- Trial name
- PRIMECare (NCT05511701)
- Testing
- CHW Care Model, Usual Care Model
- Where
- Argentina
- Volunteers
- 968 people
- Sponsor
- Harvard School of Public Health (HSPH)
Blood Pressure, Hypertension
Onco-primary Care Networking to Support TEAM-based Care
The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a…
- Conditions
- Blood Pressure, Hypertension, Cancer, Cancer, Breast
- Trial name
- ONE TEAM (NCT04258813)
- Testing
- iGuide Intervention (Self-guided), iGuide 2 Intervention (Tailored/Targeted), Control
- Where
- United States
- Volunteers
- 313 people
- Sponsor
- Duke University
Cardiovascular Diseases (CVD), Cardiovascular Disease Prevention
Assessment and Prediction of Cardiovascular Health and Disease Risk Using Wearable Biometrics.
This prospective, observational cohort study will evaluate the associations between wearable-derived biometrics and cardiovascular health, quantified by the American Heart Association's Life's Essential 8 framework, as well as…
- Conditions
- Cardiovascular Diseases (CVD), Cardiovascular Disease Prevention, Cardiovascular Disease Risk Factor, Coronary Artery Disease (CAD)
- Trial name
- BEACON-HEART (NCT07401550)
- Where
- Ireland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Rheumatoid Arthritis, Atherosclerotic Ischemic Disease
Coronary Computed Tomography Angiography In Rheumatoid Arthritis Study
The Coronary Computed Tomography Angiography in Rheumatoid Arthritis study is part of the multinational, prospective, observational Autoimmunity and Atherosclerosis in Rheumatic Diseases cohort (https://atacc-rd.com) that…
- Conditions
- Rheumatoid Arthritis, Atherosclerotic Ischemic Disease, Pulmonary Disease, Depressive Disorder
- Trial name
- COTIRA (NCT07363980)
- Where
- 4 sites in Denmark
- Volunteers
- 4,000 people
- Sponsor
- Ellen Margrethe Hauge
Prediabetic State, Metabolic Syndrome
Effects of Sweetener Consumption on Risk Factors for Heart Disease in Prediabetic Subjects
The aim of this prospective interventional study is to investigate the metabolic effects of consuming artificial and natural sweeteners in persons with prediabetes.
- Conditions
- Prediabetic State, Metabolic Syndrome, Insulin Resistance, Thrombosis
- Trial name
- Sweetheart (NCT07377097)
- Testing
- Saccharin, Sucralose, Erythritol
- Volunteers
- 80 people
- Sponsor
- Charite University, Berlin, Germany
Wearable Electronic Devices, Polygenic Risk Score
DELphi Procedure for Developing Recommendations for the Implementation of Wearable Devices and Polygenic Risk Scores
DEL-DIP is a prospective observational study employing a Delphi methodology (at least two online rounds) to elicit and consolidate the views of an expert panel within the INNOPREV project.
- Conditions
- Wearable Electronic Devices, Polygenic Risk Score, CVD - Cardiovascular Disease, Primary Prevention
- Trial name
- DEL-DIP (NCT07358481)
- Where
- Italy
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Uremia; Chronic, Cardiovascular Diseases (CVD)
Prevention and Management of Cardiovascular and Cerebrovascular Complications in Maintenance Hemodialysis (MHD) Patients
Background and Purpose: This clinical study aims to explore and validate two innovative treatment strategies to address two major challenges faced by patients on maintenance hemodialysis (uremia): the high incidence of…
- Conditions
- Uremia; Chronic, Cardiovascular Diseases (CVD), Cerebrovascular Disorders, Intradialytic Hypotension
- Trial name
- NCT07335471
- Testing
- Continuous High-Glucose Infusion and Regular Hemoperfusion in Maintenance Hemodialysis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Suzhou Municipal Hospital of Anhui Province
Gender Incongruence, Cardiovascular Disease (CVD) Risk Factors
Cardiomodulatory Effects of Gender-Affirming Hormone Therapy
Gender-affirming hormone therapy is today a well-established treatment for individuals experiencing gender-incongruence. However, little is known about the long-term effects of gender-affirming hormone therapy on the…
- Trial name
- CARMEN (NCT07128771)
- Where
- Norway
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- University Hospital, Akershus
Cardiovascular Diseases (CVD)
Comparative Study Between Antihyperlipidemic Agents in Treatment of Cardiovascular Diseases
The goal of this clinical trial is to study the efficiency and safety of using combinations of antihyperlipidemic agents with a single drug to treat cardiovascular diseases.
- Trial name
- NCT07313124
- Testing
- rosuvastatin drug, Patients received rosuvastatin ezetimibe10/10mg
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Beni-Suef University
Cardiovascular Diseases (CVD), Coronary Heart Disease (CHD)
Comparison of Two Gait Re-training Modalities During a Cardiac Rehabilitation Stay: Benefit of Orienteering Walking
Cardiovascular disease (CVD) is the leading cause of death in France for women and the second leading cause of death for men after cancer.
- Conditions
- Cardiovascular Diseases (CVD), Coronary Heart Disease (CHD), Heart Failure, Congenital Heart Disease
- Trial name
- CAMCO (NCT06941597)
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Fondation Ildys