Clinical trials: CT Angiography
Contrast Enhancement on Cardiac CT
Comparison of Contrast Agents During CT Angiography
The purpose of this study is to compare the effects of a certain contrast agent (iodixanol) to two other commonly used contrast agents called Iopamidol (Isovue) and iohexol (Omnipaque), on heart and kidney safety in patients…
- Trial name
- Visipaque (NCT01534975)
- Testing
- contrast agent
- Where
- United States
- Volunteers
- 513 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Coronary Artery Disease
Stress CT Perfusion in Patients With Chest Pain
Our hypothesis is that quantitative 3D analysis of cardiac CT images obtained during vasodilator stress can accurately identify patients presenting at the emergency department with acute chest pain due to underlying…
- Trial name
- NCT01969916
- Testing
- Regadenoson
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Chicago
Metabolic Syndrome
Effect of Aged Garlic Extract on Atherosclerosis
The investigators will be assessing the effect of Aged Garlic Extract on the coronary arteries. The investigators will enroll patients in a double blind study, where half the patients will receive placebo, and have the patients…
- Trial name
- Garlic4 (NCT01534910)
- Testing
- aged garlic extract
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Coronary Artery Diseases, Multivessel Coronary Artery Disease
SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease
The SYNTAX III Revolution trial is a randomized diagnostic research study that investigates the use of CT scan and angiogram of the heart to help doctors decide which method is the best to improve blood supply to the heart in…
- Conditions
- Coronary Artery Diseases, Multivessel Coronary Artery Disease, Heart Diseases, Cardiovascular Diseases
- Trial name
- SYNTAX III (NCT02813473)
- Testing
- Coronary Angiography, Computed Tomography (CT) scan
- Where
- 6 sites in Belgium, France and 3 more
- Volunteers
- 223 people
- Sponsor
- ECRI bv
Bradycardia
Heart Rate Reducing Therapy in Cardiac CT Using Ivabradine and Bisoprolol
Out-patients scheduled for coronary computer tomographic angiography (CCTA) were screened regarding their baseline heart rate. If heart rate was > 75, patients were pretreated with 10mg bisoprolol (group 1) or 10mg bisoprolol…
- Trial name
- NCT02764970
- Testing
- Ivabradine 7.5mg orally
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Medical University of Graz
Coronary Artery Disease
Role of On-site CT-derived FFR in the Management of Suspect CAD Patients
The primary of this registry is to evaluate whether the availability of CTA/CT-FFR procedure could effectively optimize the flow of clinical practice of stable chest pain versus conventional clinical pathway in decision making…
- Trial name
- TARGET (NCT03901326)
- Testing
- CT-FFR assessment
- Where
- China
- Volunteers
- 1,216 people
- Sponsor
- Chinese PLA General Hospital
Liver Blood Supply
3T MR Angiography of the Hepatic Vasculature
This study plans to learn more about the two Magnetic Resonance Angiography (MRA) techniques.
- Trial name
- NCT02299934
- Testing
- Magnetic Resonance Imaging (MRI), Compurtized Tomgraphy (CT)
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Coronary Heart Disease, Coronary Artery Disease
Cardiogoniometry for Detecting Coronary Artery Disease by CT Angiography
Cardiogoniometry is a technique to process and evaluate vectorcardiography from regular ECG acquisitions. Vectorcardiography has a long tradition in cardiology for providing comprehensive information on myocardial function and…
- Conditions
- Coronary Heart Disease, Coronary Artery Disease, Ischemic Heart Disease
- Trial name
- NCT02725671
- Testing
- Explorer
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Ultra-high-resolution CT vs. Conventional Angiography for Detecting Coronary Heart Disease
Cardiac catheterization with invasive coronary angiography is the gold standard for determining the presence or absence of significant coronary heart disease (CHD).
- Trial name
- NCT04272060
- Testing
- CT angiography, Invasive coronary angiography
- Where
- 3 sites in United States, Brazil and 1 more
- Volunteers
- 175 people
- Sponsor
- Johns Hopkins University
Acute Coronary Syndromes, Coronary Artery Disease
Computed Tomographic Coronary Angiography for Acute Chest Pain Evaluation
The purpose of this study is to evaluate whether 64-slice Computed Tomographic coronary angiography is useful for rapid diagnosis or exclusion of significant coronary artery disease in patients who present to the Emergency…
- Trial name
- EDCCTA (NCT00615719)
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Virginia Commonwealth University
Coronary Artery Disease
Xenetix® 350: Comparative Assessment of Image Quality for Coronary CT Angiography
The purpose of this study is to demonstrate the (statistical) non-inferiority of iobitridol (Xenetix® 350) when compared to contrast agents with higher iodine concentrations, iopromide (Ultravist® 370) and iomeprol (Iomeron® 400)…
- Trial name
- X-ACT (NCT01255722)
- Testing
- iobitridol, iopromide, iomeprol
- Where
- 23 sites in France, Germany and 3 more
- Volunteers
- 468 people
- Sponsor
- Guerbet
Coronary Artery Disease
Coronary MDCTA With Iopamidol Injection 370
Determine the validity and compare the visualization of arterial segments obtained with 3 doses of iopamidol to determine dose for further investigation in future trials.
- Trial name
- NCT00558792
- Testing
- Isovue 370, 70 mL, Isovue 370, 80 mL, Isovue 370, 90 mL
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- Bracco Diagnostics, Inc
Coronary Artery Disease
Screening For Asymptomatic Obstructive Coronary Artery Disease Among High-Risk Diabetic Patients Using CT Angiography, Following Core 64
Patients with a known history of diabetes mellitus and no prior documented evidence of cardiovascular disease will be evaluated for inclusion in the study.
- Trial name
- faCTor-64 (NCT00488033)
- Testing
- CT Angiography
- Where
- United States
- Volunteers
- 900 people
- Sponsor
- Intermountain Health Care, Inc.
Atherosclerosis
Rivaroxaban Versus Warfarin in the Evaluation of Progression of Coronary Calcium
Current oral anti-coagulation for atrial fibrillation is most commonly performed with warfarin. Warfarin is a vitamin K antagonist that has been shown in non-randomized trials to increase vascular calcification.
- Trial name
- NCT02376010
- Testing
- rivaroxaban, Warfarin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Carotid Stenosis
[F-18] RGD-K5 Positron Emission Tomography (PET) in Participants With Carotid Artery Stenosis
This trial will be the first trial for the Investigation Product (IP), [F-18]RGD-K5 for carotid plaque imaging and will be conducted as a Phase II trial since this compound has already been tested in humans for phase I and phase…
- Trial name
- NCT01602471
- Testing
- [F-18]RDG-K5
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Siemens Molecular Imaging
Intracerebral Hemorrhage
The Spot Sign for Predicting and Treating ICH Growth Study
The purpose of this study is to determine if computed tomography angiography can predict which individuals with intracerebral hemorrhage will experience significant growth in the size of the hemorrhage.
- Trial name
- STOP-IT (NCT00810888)
- Testing
- recombinant activated factor VII
- Where
- 10 sites in United States, Canada
- Volunteers
- 92 people
- Sponsor
- University of Cincinnati
Chest Pain, Acute Coronary Syndrome
Computed Tomography Coronary Angiogram (CTCA) Versus Traditional Care in Emergency Department Assessment of Potential Acute Coronary Syndromes (ACS)
This multi-center, randomized, controlled trial conducted in Emergency Departments (ED) compares computed tomography (CT) coronary angiography with the traditional approach (usual care) for low- to intermediate-risk chest pain…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Acute Myocardial Infarction, Coronary Artery Disease
- Trial name
- NCT00933400
- Testing
- CT Coronary Angiography (CTCA), Traditional Strategy
- Where
- 5 sites in United States
- Volunteers
- 1,392 people
- Sponsor
- American College of Radiology
Enlarged Prostate
3D Rotational CT Angiogram With Embolization Guidance and CBCT in Prostatic Artery Embolization
The purpose of this research study is to learn about how cone-beam Computerized Tomography scans (X-ray images taken from different angles) work together with an embolization guidance software (helps the doctor see the arteries…
- Trial name
- NCT03164629
- Testing
- cone-beam CT 3D Emboguide
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Miami
Coronary Artery Disease
Clinical Evaluation of the CADence Device in Detection of Coronary Artery Diseases
This is a multi-center, prospective, non-randomized, double-blinded trial to evaluate the sensitivity and specificity of the CADence device in detecting the existence of clinically significant coronary artery disease as…
- Trial name
- TURBULENCE (NCT01743040)
- Testing
- CADence
- Where
- 24 sites in United States
- Volunteers
- 1,014 people
- Sponsor
- AUM Cardiovascular, Inc.
Type 2 Diabetes Mellitus, Coronary Atherosclerosis
Assessment With CCTA and MRI in Asymptomatic Patients With Type 2 Diabetes for Detection of Unrecognized Myocardial Scar in Subclinical Coronary Atherosclerosis
The study aimed to prospectively investigate the prevalence of myocardial scar on Dotarem-enhanced Cardiovascular Magnetic Resonance Imaging (MRI) in asymptomatic patients with type-2 Diabetes Mellitus and to assess its…
- Trial name
- ACCREDIT (NCT01254552)
- Testing
- iobitridol, gadoterate meglumine
- Where
- South Korea
- Volunteers
- 351 people
- Sponsor
- Guerbet