Clinical trials: CT
Late Onset Alzheimer Disease
Measuring Brain Amyloid Plaque Load in Older Adults Using BAY 94-9172
The overall goal of this project is to establish and validate biomarkers associated with the risk and progression of late onset Alzheimer's disease, mild cognitive impairment and cognitive decline.
- Trial name
- NCT01222351
- Testing
- BAY 94-9172 (Florbetaben)
- Where
- United States
- Volunteers
- 161 people
- Sponsor
- New York State Psychiatric Institute
Neoplasm
Radiation Dosimetry, Metabolism, Safety, Tolerability and Positron Emission Tomography/Computed Tomography (PET/CT) Imaging With BAY 85-8050 in Healthy Volunteers and Patients
This study is a visual assessment of diagnostic PET/CT images obtained after a single intravenous injection of BAY85-8050 in patients with cancer
- Trial name
- NCT00961831
- Testing
- F-18 (BAY85-8050)
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bayer
Epithelial Ovarian Cancer
[18F]Fluoro-PEG-folate PET/CT Imaging in Epithelial Ovarian Cancer
The pre-operative assessment of intra-abdominal tumor load in patients with epithelial ovarian cancer (EOC) remains unreliable with standard imaging modalities.
- Trial name
- NCT05215496
- Testing
- [18F]fluoro-PEG-folate PET/CT scan
- Where
- Netherlands
- Volunteers
- 5 people
- Sponsor
- Lioe-Fee de Geus-Oei, MD PhD
Diabetes Mellitus
Coronary CT Angiography in Asymptomatic Diabetes Mellitus
The study aims to examine if non-invasive imaging of the coronary arteries by CT angiography using an intra-venous injection of X-ray contrast medium in asymptomatic patients with adult onset diabetes mellitus can predict the…
- Trial name
- NCT00321542
- Testing
- Imaging study, No intervention
- Where
- Israel
- Volunteers
- 793 people
- Sponsor
- Carmel Medical Center
Pulmonary Embolism and Thrombosis, Deterioration, Clinical
Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography
The investigators aim to build a predictive tool for Adverse Outcome of Acute Pulmonary Embolism by Artificial Intelligence System Based on CT Pulmonary Angiography.
- Conditions
- Pulmonary Embolism and Thrombosis, Deterioration, Clinical, Artificial Intelligence
- Trial name
- PEAICTPA (NCT05482269)
- Testing
- no intervention
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Shengjing Hospital
Prostate Cancer, Prostate Adenocarcinoma
Multi-modality Imaging (PCa) Using Sodium MRI and PSMA PET in Men Pre-prostatectomy
The study is a non-randomized, prospective trial of men scheduled for radical prostatectomy for treatment of prostate cancer as standard of care and will undergo a series of pre-operative multi-modality imaging studies.
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Prostate Neoplasm
- Trial name
- IGPC-5 (NCT04053842)
- Testing
- PET Scan, [18F]PSMA-1007 Injection, Sodium MRI
- Where
- Canada
- Volunteers
- 16 people
- Sponsor
- Glenn Bauman
Schizophrenia / Schizoaffective Disorder
NST-SPARK Open-Label Phase 1 STTR (IGNITE)
Schizophrenia Spectrum disorders (SSD) are among the most devastating psychiatric disorders. Prominent negative symptoms such as low motivation, anhedonia, asociality, and emotional flattening are experienced by up to 60% of…
- Trial name
- IGNITE (NCT07593456)
- Testing
- NST-SPARK
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- North Shore Therapeutics, Inc.
Rheumatoid Arthritis, Ankylosing Spondylarthritis
Yuflyma® (Adalimumab), Patient Experience After Switching
Patient preference and experience can impact patients' adherence and persistence regarding a treatment, especially when switching.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylarthritis, Axial Spondyloarthritis Without Radiographic Evidence of Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- YU-MATTER (NCT05427942)
- Testing
- Adalimumab
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- Celltrion HealthCare France
Axial Spondyloarthritis
Comparison of CT Scan Between Patients With Axial Spondyloarthritis and Control Subjects
The aim of this study is to define structural damage to the manubriosternal joint (MST) in axial spondyloarthritis (axSpA) by comparing its CT scan aspects between a population of patients with radiographic (axSpA) and a control…
- Trial name
- SPA-THORAX (NCT05779969)
- Testing
- Chest CT scan
- Where
- France
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Hôpital NOVO
Gastric Cancer, Gastroesophageal Cancer
Overall Survival of Inoperable Gastric/GastroOesophageal Cancer Subjects on Treating With LMWH + Chemotherapy(CT) vs Standard CT
Due to evidence available both in terms of efficacy and safety of low molecular weight heparin, its use for the prevention of thromboembolic disease in cancer patients undergoing surgical intervention, and its extended use in…
- Trial name
- GASTRANOX (NCT00718354)
- Testing
- Enoxaparin, Standard Chemotherapy
- Where
- 15 sites in India
- Volunteers
- 740 people
- Sponsor
- Thrombosis Research Institute
Coronary Artery Disease, OCT Angiography
Coronary Evaluation And Guided Lesion Exploration Using Photon-counting CT and Intracoronary Imaging Techniques
This study evaluates the diagnostic accuracy and limitations of photon-counting computed tomography (PCCT) in characterizing coronary plaque, with comparisons to optical coherence tomography (OCT) and intravascular ultrasound…
- Conditions
- Coronary Artery Disease, OCT Angiography, CT
- Trial name
- C-EAGLE (NCT07036770)
- Testing
- Coronary CT scan using photon-counting CT
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Gastroesophageal Junction Adenocarcinoma
Neoadjuvant RCT Versus CT for Patients With Locally Advanced, Potentially Resectable Adenocarcinoma of the GEJ
This is a multicenter, prospective, randomized, stratified, controlled, open-label study comparing neoadjuvant radiochemotherapy with FLOT versus FLOT chemotherapy alone für patients with locally advanced, potentially resectable…
- Trial name
- NCT04375605
- Testing
- 5-Fluorouracil, Calcium folinate, Oxaliplatin
- Where
- Germany
- Volunteers
- 342 people
- Sponsor
- Universitätsmedizin Mannheim
Pelvic Cancer, Abdominal Cancer
IV Contrast-Enhanced Cone Beam Computed Tomography (CBCT) in Radiotherapy
The purpose of this study is to find out if giving intravenous (IV) contrast (a liquid that helps with the visibility of organs and blood vessels that is given through the vein with the use of a hollow needle) during a Cone Beam…
- Trial name
- NCT04199754
- Testing
- Omnipaque 300mg/mL Solution for Injection, Cone Beam CT, Radiation Therapy
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Columbia University
Short-Term Renal-Hematologic Safety, Contrast-Enhanced MRI and FDG-PET/CT
Comparative Evaluation of Contrast-Enhanced MRI and FDG-PET/CT in Spinal Pathology: Image Quality and Short-Term Renal-Hematologic Safety
This prospective comparative observational study evaluates image quality characteristics and short-term physiological effects associated with contrast-enhanced magnetic resonance imaging (MRI) and fluorodeoxyglucose positron…
- Conditions
- Short-Term Renal-Hematologic Safety, Contrast-Enhanced MRI and FDG-PET/CT, Spinal Pathology
- Trial name
- NCT07640386
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Chest Pain, Coronary Heart Disease Risk
Comparison of the Cost-Effectiveness of Coronary CT Angiography Versus Myocardial SPECT in Patients With Intermediate Risk of Coronary Heart Disease
The investigators aim to compare the cost-effectiveness of CCTA and myocardial SPECT in patients with intermediate pre-test probability of CHD.
- Trial name
- CARE-CCTA (NCT01542086)
- Testing
- Myocardial SPECT, 64-channel coronary CT angiography (CCTA)
- Where
- South Korea
- Volunteers
- 1,050 people
- Sponsor
- Seoul National University Hospital
Autoimmune Disease, Crohn Disease
Fluorine F 18 Clofarabine PET/CT in Imaging Patients With Autoimmune or Inflammatory Diseases
This pilot trial studies how well fluorine F 18 clofarabine positron emission tomography (PET)/computed tomography (CT) works in imaging patients with autoimmune or inflammatory diseases.
- Conditions
- Autoimmune Disease, Crohn Disease, Inflammatory Disorder, Rheumatoid Arthritis
- Trial name
- NCT02925351
- Testing
- Computed Tomography, Fluorine F 18 Clofarabine, Positron Emission Tomography
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Endometrial Cancer
Usefulness of 18F-FDG PET/CT in the Initial Staging and Surveillance of Endometrial Cancer Patients
1. To assess the value of 18F-FDG PET/CT in the initial staging and detection of recurrent cases of endometrial cancer. 2. To determine correlation between PET/CT derived parameters including SUVmax, TLG and MTV and…
- Trial name
- PET/CT (NCT05056259)
- Testing
- 18F-FDG PET/CT
- Volunteers
- 42 people
- Sponsor
- Assiut University
Cervical Cancer
HPV Serum Level and FDG PET CT in Patients With Cervical Cancer Treated With Radical Radiochemotherapy
The main purpose of the study is to describe changes in plasma HPV DNA levels in patients with locally advanced cervical cancer during radical radiochemotherapy (CRT) and to correlate changes with response to treatment.
- Trial name
- HPV-RICCO (NCT04683549)
- Testing
- HPV serum level and FDG PET CT in patients with cervical cancer treated with radical radiochemotherapy
- Where
- Poland
- Volunteers
- 30 people
- Sponsor
- The Greater Poland Cancer Centre
Amyloid, Amyloid Cardiomyopathy
18F-florbetaben PET-CT to Non-invasively Diagnose Cardiac AL Amyloidosis
Amyloidoses are systemic or acquired disorders characterized by the deposition in the extracellular spaces of amyloid fibers formed by proteins codified by mutated genes or non-mutated but misfolded proteins.
- Trial name
- PETAL (NCT06048601)
- Testing
- 18F-florbetaben PET/CT
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Toscana Gabriele Monasterio
Cardiac Sarcoidosis
Macrophage PET/CT Imaging Using 64Cu-DOTATATE for the Diagnosis of Cardiac Sarcoidosis
The purpose of the CuDOSIS study is to examine the diagnostic value of activated macrophage imaging in patients with or under evaluation for cardiac sarcoidosis.
- Trial name
- CuDOSIS (NCT06131112)
- Testing
- 64Cu-DOTATATE PET/CT scan
- Where
- Denmark
- Volunteers
- 76 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet