Clinical trials: CRP
Inflammation, Smoking Cessation
Screening and Multiple Intervention on Lung Epidemics
This prospective randomized pilot trial will evaluate a multiple intervention program of prevention in lifelong smokers aiming at reduction of chronic inflammation status through treatment with low-dose acetylsalicylic acid…
- Conditions
- Inflammation, Smoking Cessation, Diet Modification, Physical Activity
- Trial name
- SMILE (NCT03654105)
- Testing
- Cytisine, Acetylsalicylic acid, Diet Modification and Physical Activity Increase
- Where
- Italy
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Psoriasis
The Disease Severity In Patients With Psoriasis
This observational study aims to evaluate new markers to predict disease activity in psoriasis. The main question is SGOT, SGPT, GGT, hs-CRP, and apo B related to disease severity in psoriasis.
- Trial name
- NCT05943405
- Where
- Indonesia
- Volunteers
- 33 people
- Sponsor
- Universitas Sebelas Maret
Obesity, Diabetes
Calorie Restriction and Changes in Body Composition, Disease, Function, and Quality of Life in Older Adults
The investigators want to determine if the benefits of weight loss outweigh the potential risk in a group of older adults. The investigators will test the hypothesis that changes in diet composition alone or in conjunction with…
- Conditions
- Obesity, Diabetes, Hypertension, Hyperlipidemia
- Trial name
- CROSSROADS (NCT00955903)
- Testing
- Exercise, Reduced Calorie Diet, Weight Maintenance Diet
- Where
- United States
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Inflammation, C-reactive Protein
What is the Effect of Increased Consumption of Fruit Juice on Exercise Capacity and Inflammatory Biomarkers?
Dietary patterns and physical inactivity common in Western societies have been associated with chronic low-grade inflammation and an increased risk of non-communicable health conditions.
- Conditions
- Inflammation, C-reactive Protein, Exercise Capacity
- Trial name
- NCT07862049
- Testing
- Active Fruit Juice Intervention, Control Fruit Juice Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Northwell Health
Depression, Inflammation
Tofacitinib in Depression (TIDE)
This study will test whether 7-10 day administration of the anti-inflammatory drug, tofacitinib, has positive effects on people experiencing treatment-resistant depression compared to placebo.
- Trial name
- TIDE (NCT04141904)
- Testing
- Tofacitinib 5 MG [Xeljanz]
- Where
- United Kingdom
- Volunteers
- 2 people
- Sponsor
- University of Oxford
Malondialdehyde, Heme Oxygenase
The Effects of Two Anesthetic Drugs on Some Enzyme Levels in Patients Undergoing Lower Extremity Surgery
The primary aim of this study was to compare the effects of dexmedetomidine and ketamine, which are administered intravenously during surgery, on the levels of malondialdehyde, an antioxidant, anti-inflammatory enzyme, heme…
- Conditions
- Malondialdehyde, Heme Oxygenase, C-Reactive Protein
- Trial name
- NCT05950555
- Testing
- Saline, Dexmedetomidine, Ketamine
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
THYROTOXICOSIS
The Association Between Autoimmune or Inflammation and Thyroid Disease
This study aims to evaluate the effects of thyroid functions on energy homeostasis and inflammation.
- Trial name
- NCT02886949
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Taichung Veterans General Hospital
Colorectal Cancer
Inflammation Biomarkers in the Diagnosis of Postoperative Infectious Complications in Colorectal Cancer Surgery
This is a longitudinal, single-center, prospective study to determine the efficiency of WBC Count, CRP, PCT, Neutrophil CD64 and Monocyte Human Leukocyte Antigen- DR in the diagnosis of postoperative infectious complications in…
- Trial name
- NCT03559335
- Where
- Russia
- Volunteers
- 100 people
- Sponsor
- State Scientific Centre of Coloproctology, Russian Federation
Antibiotic Resistant Infection, Critical Illness
CD64 and Antibiotics in Human Sepsis
The purpose of the study is to find out whether CD64 expression on neutrophils measured by a new bedside test (LeukoDx) within 30 minutes is associated with effective antibiotic therapy in critically ill adult patients at risk of…
- Conditions
- Antibiotic Resistant Infection, Critical Illness, SIRS, Sepsis
- Trial name
- CD64SEPLDX (NCT02922998)
- Where
- Germany
- Volunteers
- 64 people
- Sponsor
- University of Ulm
Alcohols, Cardiovascular Diseases
Postprandial Effect of Chinese Tea Flavor Liquor on Selected CVD Risk Factors
Background: human studies of Chinese liquor are sparse. we hypothesis that Chinese Tea Flavor liquor may be beneficial to CVD risk factors postprandially.
- Trial name
- TFL (NCT01264666)
- Testing
- Chinese tea flavor liquor, Chinese Meijiao liquor, Water control
- Where
- China
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Zhejiang University
Essential Hypertension
Safety and Efficacy of Ramipril in the Treatment of Essential Hypertension
The purpose of this study is to assess which drug is more effective of Ramiprin®(ramipril) and Tritace®(ramipril) in the Treatment of Essential Hypertension
- Trial name
- NCT00366119
- Testing
- Ramipril
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Pacific Pharmaceuticals
Sepsis, Systemic Infection
CRP,CRP/Alb Ratio, N/L Ratio in Predictors of Both Systemic Infection and Survival in Patient With Sepsis in Assiut University Hospitals
the goal of this study is to asses the value of biomarker (CRP, CRP/Alb ratio, N/L ratio) in predictor of the outcome in normotensive patients with sepsis.
- Trial name
- NCT06586372
- Volunteers
- 100 people
- Sponsor
- Assiut University
Atherosclerosis, Type 2 Diabetes
High-sensitivity C-reactive Protein and United Kingdom Prospective Diabetes Study (UKPDS) Risk Score in Type 2 Diabetes
The UKPDS risk score is recommended to assess global risk for future coronary heart disease (CHD) events in primary prevention. Recently, high-sensitivity C-reactive protein (hsCRP) has emerged as a strong independent risk factor…
- Trial name
- NCT01099865
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Korea University
Cesarean Delivery Affecting Newborn, Anesthesia
Hs-CRP and NLR as Markers of Perioperative Stress
The stress response to surgery is a result of tissue injury with local and systemic inflammation that contributes to the postoperative outcome.
- Conditions
- Cesarean Delivery Affecting Newborn, Anesthesia, Inflammatory Response
- Trial name
- NCT03594695
- Testing
- HSCRP and NLR
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ufuk University
Rheumatoid Arthritis (RA), Remote Patient Monitoring
BloodTrackR Usability and Concordance Study (BUCS): Evaluating a Smart Home-Based Blood Collection Platform for Remote Monitoring in Rheumatoid Arthritis
The BloodTrackR Usability and Concordance Study (BUCS) is evaluating a novel home-based blood collection device and companion mobile application for people with rheumatoid arthritis.
- Trial name
- BUCS (NCT07660029)
- Testing
- BloodTrackR - Home Blood Collection Platform
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Ulster
Neonatal Sepsis, Preterm Infants
Effect of Vitamin D as Adjuvant Therapy in Preterm Infants With Neonatal Sepsis
The goal of this clinical trial is to learn the effect of vitamin D as an adjunctive therapy for preterm neonates with sepsis measured by the outcomes, which are sepsis score and C-reactive protein after 7 days.
- Trial name
- NCT07245277
- Testing
- Vitamin D
- Where
- 2 sites in Indonesia
- Volunteers
- 78 people
- Sponsor
- Universitas Padjadjaran
Metabolic Disease
Husk Fiber Intervention on Metabolic Health of Centrally Obese School Teachers
A group of 120 school teachers (male=60, female=60) was divided into four subgroups for sixteen weeks of an interventional study. One group was kept in control while the other three groups were assigned intervention.
- Trial name
- NCT06188728
- Testing
- effect of 10 gm psyllium husk fiber twice a day, 30 minutes before breakfast and dinner, Effect of life style modification (Diet, Behavior and physical activity), Combined effect of 10 gm Psyllium husk fiber and lifestyle modification
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Peshawar
Periodontitis, Periodontitis Stage I
Hypochlorous Acid in Non-Surgical Periodontal Therapy
Periodontitis is a chronic inflammatory disease associated with dental plaque and characterized by the progressive destruction of the tooth-supporting tissues.
- Conditions
- Periodontitis, Periodontitis Stage I, Periodontitis Stage II
- Trial name
- NCT07712627
- Testing
- Hypochlorous Acid Application, Scaling and Root Planing (SRP) with Purified Water
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Ataturk University
Inflammation, Fungal Infection
Effect of Inflammation on Voriconazole Concentration
Voriconazole is a broad-spectrum antifungal agent. There is evidence for a relation between the efficacy and safety of voriconazole and voriconazole trough concentrations.
- Trial name
- NCT02074462
- Where
- Netherlands
- Volunteers
- 36 people
- Sponsor
- University Medical Center Groningen
Obstructive Sleep Apnoea Hypopnoea Syndrome, Biomarkers of Fibrin Clot Structure
New Markers to Measure Clotting in Patients With the Obstructive Sleep Apnoea Hypopnoea Syndrome
Obstructive Sleep Apnoea Hypopnoea Syndrome(OSAHS)affects at least 4% of males and 2% of females. OSAHS is the combination of excessive daytime sleepiness, snoring and apnoeas (stopping breathing at night).
- Conditions
- Obstructive Sleep Apnoea Hypopnoea Syndrome, Biomarkers of Fibrin Clot Structure, Biomarkers of Vascular Endothelial Injury
- Trial name
- NCT01525160
- Where
- United Kingdom
- Volunteers
- 66 people
- Sponsor
- Hywel Dda Health Board