Clinical trials: CRC Screening
Colorectal Cancer
SMARTER: Using Blood Samples to iMprove FIT-bAsed coloRecTal cancEr scReening
The project aims to investigate whether colorectal cancer screening can be improved using blood tests, thereby reducing the number of unnecessary colonoscopies.
- Trial name
- NCT06714318
- Where
- 2 sites in Denmark
- Volunteers
- 1,000 people
- Sponsor
- Vejle Hospital
Colorectal Cancer
Development of a Serum Test for Colorectal Cancer Screening (COLODIAG préclinique)
Colorectal cancer (CRC) is a major public health problem, with 44,872 new cases per year in France (3rd most common cancer), and 17,684 deaths (2nd cause of death from cancer).
- Trial name
- COLODIAG pre (NCT04659018)
- Testing
- blood collection
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Colorectal Cancer, Screening
Information About a Doctor or a Possibility of Choosing Doctor's Gender and Attendance to Screening Colonoscopy
The purpose of the study is to investigate whether the information about a doctor or possibility to choose doctor's gender included in invitation letter is associated with attendance rate to screening colonoscopy.
- Trial name
- NCT01182922
- Testing
- Invitation letter
- Where
- Poland
- Volunteers
- 5,100 people
- Sponsor
- Maria Sklodowska-Curie National Research Institute of Oncology
Colorectal Cancer, Breast Cancer
A Sustainable Approach to Increasing Cancer Screening
Parent study: A Coordinated Approach to Cancer and Health (CATCH), was designed to compare the efficacy of two intervention arms (described below) intended to increase breast, cervical, and colon cancer screening rates among…
- Conditions
- Colorectal Cancer, Breast Cancer, Cervical Cancer
- Trial name
- CATCH (NCT01395459)
- Testing
- IVR only, IVR+PCC
- Where
- United States
- Volunteers
- 13,675 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Colonoscopy
Impact of Digital Tools on the Quality of Bowel Preparation for Colonoscopy
This is a single blinded randomized controlled study. The main question of this study is whether better preparation by making full use of digital tools can increase patient compliance with the preparation methods for colonoscopy…
- Trial name
- NCT05734079
- Testing
- Standard of care, Standard of care + Video call, Standard of care + Video call + Educational video film
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Ziv Hospital
Colorectal Cancer Screening, Cervical Cancer Screening
Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas
In this study, the investigators will deliver self-sampling human papillomavirus (HPV) tests and fecal immunochemical test (FIT) kits, as well as adapted cancer screening educational materials, by mail to 110 women who are…
- Trial name
- NCT04471194
- Testing
- Self-sampling HPV test, Fecal occult blood test
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Colorectal Cancer
Assessing the Effect of a Blood-based Colorectal Cancer Screening Test on Screening Adherence and Colonoscopy Completion
Objectives: Colonoscopy and stool-based testing are the two predominant colorectal cancer (CRC) screening tests used in the US, and both reduce colorectal cancer mortality.
- Trial name
- NCT03598166
- Testing
- Septin9
- Where
- United States
- Volunteers
- 359 people, healthy volunteers welcome
- Sponsor
- Peter S. Liang, MD MPH
Colorectal Cancer
Effectiveness of Decision-aid Video on Colorectal Cancer Screening
Colorectal cancer (CRC) is the second most common cancer in Malaysia. Diagnosing CRC at early stage is crucial to reduce their mortality risk. To achieve this aim, CRC screening promotion intervention is deemed necessary.
- Trial name
- DAVOCS (NCT04692987)
- Testing
- Decision-aid video
- Where
- Malaysia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Colorectal Cancer
Feasibility of Reduction in Right Sided Bowel Cancer Through Contrast Enhanced Colonoscopy
The Bowel Cancer Screening program was implemented to address the important issue of prevention and early detection of bowel cancer.
- Trial name
- CONSCOP (NCT01972451)
- Testing
- Colonoscopy with enhanced dye
- Where
- United Kingdom
- Volunteers
- 1,320 people
- Sponsor
- Lisette Nixon
Cancer Prevention
Increasing Breast, Cervical, and Colorectal Cancer Screening and HPV Vaccination Among Underserved Texans
This study involves a partnership between UTHealth School of Public Health and the Texas 2-1-1 service, which is a helpline connecting low-income and minority callers with a number of needed services.
- Trial name
- NCT04638010
- Testing
- Cancer control navigation (CNN), General referral (usual care)
- Where
- United States
- Volunteers
- 1,554 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Colorectal Cancer Screening
Additional Mailed FIT Kits
This study aims to assess whether sending patients in a county health care system additional FIT Kits can increase the FIT Kit return rate enough to warrant the extra cost.
- Trial name
- NCT06805370
- Testing
- Mailed Additional FIT Kit, Usual Care
- Where
- United States
- Volunteers
- 1,700 people
- Sponsor
- University of Southern California
Colonoscopy, Colorectal Cancer Screening
Water Exchange Colonoscopy in Elderly Patients
Colonoscopy is an important test for detecting colorectal polyps and cancer, but it can cause pain and discomfort, especially in older adults. Traditional colonoscopy uses air to expand the colon.
- Trial name
- NCT07830823
- Testing
- Water exchange colonoscopy, Gas insufflation colonoscopy, Propofol and opioid anesthesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- First People's Hospital Of Lin'an District, Hangzhou
Colorectal Cancer
The Culture of Advanced/Recurrent/Metastatic Colorectal Cancer Organoids and Drug Screening
The study aims to establish an organoids platform and apply them to screen drugs for advanced/recurrent/metastatic colorectal cancer patients.
- Trial name
- NCT05304741
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Chongqing University Cancer Hospital
Colorectal Cancer Screening
Pilot Study of the National Colorectal Cancer Roundtable Toolbox (NCCRT) to Increase Colorectal Cancer Screening Rates
The American Cancer Society and The Centers for Disease Control and Prevention in collaboration with The National Colorectal Cancer Roundtable published "How to Increase Colorectal Cancer Screening rates in Practice: A Primary…
- Trial name
- NCT00503737
- Testing
- National Colorectal Cancer Roundtable Toolbox
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Colorectal Cancer
Microbiome Testing for the Screening of Colorectal Cancer
Colorectal cancer (CRC) is one of the most common cancer and cause of cancer death worldwide. Population-based screening programs for average-risk populations have proven effective in reducing both incidence and mortality of CRC…
- Trial name
- NI-GUILTI (NCT06588166)
- Testing
- Gut microbiome testing
- Where
- Italy
- Volunteers
- 1,006 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Hereditary Colorectal Cancer
Next-generation Sequencing of Colorectal Cancer Somatic Cells to Guide Genetic Susceptibility Gene Mutations Screening.
This is a prospective, single-center, clinical study.This study is to evaluate the feasibility of genetic susceptibility screening based on the detection of tumor tissue mutations by a NGS panel.
- Trial name
- NCT04280666
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fudan University
Colorectal Cancer, Polyp of Colon
Hybrid-sensor Breath Analysis for Colorectal Cancer Screening
The aim of this project is to promote the breath volatile marker concept for colorectal cancer (CRC) screening by advancing developing the application of a novel hybrid analyzer for the purpose.
- Trial name
- HYCOR (NCT05173077)
- Testing
- Identification of specific VOCs in CRC tissue surgery material, Secondary validation study in general CRC screening settings, Breath sampling for VOC detection
- Where
- Latvia
- Volunteers
- 3,000 people
- Sponsor
- University of Latvia
Colorectal Cancer
Translation of Colorectal Cancer Screening Guidelines to Practice: A System Intervention
Colorectal cancer (CRC) is the second leading cause of cancer-related deaths in the United States. Results from randomized clinical trials and intervention studies have suggested that implementation of a CRC screening program for…
- Trial name
- NCT00122187
- Testing
- Electronic Consult System
- Where
- 9 sites in United States
- Volunteers
- 8 people
- Sponsor
- US Department of Veterans Affairs
Metastatic Colorectal Cancer, Stage II/III Colon Cancer
A Screening Study Targeting Tumor-specific Antigens
The purpose of this study is to identify patients who may be eligible to participate in a separate Phase 2/3 treatment study evaluating an individualized neoantigen vaccine GRANITE for first line (1L) maintenance treatment of…
- Trial name
- NCT05158621
- Testing
- blood collection for research (next generation sequencing [NGS]), blood collection for research (HLA typing), blood collection for research (circulating tumor DNA [ctDNA])
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Gritstone bio, Inc.
Colorectal Cancer
Barriers to Care in Patients With Rectal Bleeding in Nigeria
This study sought to find the health seeking behavior of patients with rectal bleeding as related to their risk to develop colorectal cancer and also assess the general practitioner's perceived barriers to colonoscopy for…
- Trial name
- NCT02855385
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Obafemi Awolowo University Teaching Hospital