Clinical trials: COW'S MILK ALLERGY
Cow's Milk Allergy
Oral Immunotherapy in Cow's Milk Allergy (CMA) in Children : "Petit Lait" Study
Prospective study Main objective: to evaluate the efficiency and the security of two protocols of immunotherapy (raw milk versus heated milk) in a cohort of children with persistent Immunoglobulin E (IgE) mediated CMA (IgE-CMA).
- Trial name
- Petit Lait (NCT02465905)
- Testing
- raw milk, Heated milk
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Dr Flore AMAT
Infant Development
Acceptability and Tolerance Study of an Amino Acid Formula with HMOs
To evaluate the acceptability (including gastrointestinal tolerance and compliance) of a hypoallergenic amino acid infant formula with HMOs for the dietary management of cows' milk allergy in infants less than 12 months of age.
- Trial name
- NCT04575298
- Testing
- Acceptability, tolerance study for an infant formula with human milk oligosaccharides
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Société des Produits Nestlé (SPN)
Cow's Milk Protein Allergy
Post-failure Stepwise Heat-Denaturated Protein Introduction for Tolerance Induction in Cow's Milk Allergy Observational Cohort Study
Subjects who failed to become tolerant within 12 months after randomization within one of the three arms in the TEHITI study, can participate in the post-TEHITI observational trial to study the natural tolerance induction process.
- Trial name
- Post-TEHITI (NCT07448740)
- Where
- 5 sites in Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Milk Allergy
OIT and Xolair® (Omalizumab) in Cow's Milk Allergy
Food allergy affects up to 4% of the U.S. population and is most common in young children. Milk allergy is the most common cause of food allergy in infants and young children, and usually develops in the first year of life.
- Trial name
- NCT01157117
- Testing
- Omalizumab, Milk powder
- Where
- 3 sites in United States
- Volunteers
- 77 people
- Sponsor
- Hugh A Sampson, MD
Mild to Moderate Cows' Milk Protein Allergy
Tolerance of Extensive Hydrolyzed Whey Protein Milk Among Infant With Mild to Moderate CMPA
The goal of this clinical trial is to evaluate the tolerance, safety and efficacy of Nutribaby Royal Pepti Junior (NR Pepti) among infants with mild to moderate Cow's Milk Protein Allergy (CMPA).
- Trial name
- PEACE (NCT06204770)
- Testing
- extensive hydrolyzed protein formula
- Where
- 5 sites in Indonesia
- Volunteers
- 15 people
- Sponsor
- Danone Specialized Nutrition Indonesia
Bone Mineral Density in Cow's Milk Allergic Patients
Young Adults With Life Threatening Cow's Milk Allergy: Risks of Decrease Bone Mineralization and Methods of Calcium Supplementation
Diet is the only source for calcium and the most important dietary source are dairy products. This presents a difficulty for children with IgE-mediated cow's milk allergy, who are unable to consume milk.
- Trial name
- NCT01930266
- Testing
- Experimental, Active comparator
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Food Allergy
Nutrition in Children With Food Allergy
The investigators aim to asses the effect of dieto-therapy and of nutritional counseling on the nutritional status, body growth and tolerance acquisition in children with cow's milk allergy.
- Trial name
- NCT01583907
- Where
- Italy
- Volunteers
- 70 people
- Sponsor
- Federico II University
Cow Milk Allergy, Tolerance
Testing Tolerance in Cow Milk Protein Allergy Patients: Milk Ladder or Direct Milk Administration?
Majority of children outgrow their allergies, however there are two different methods to re-introduce milk products in the infant diet either direct milk intake in escalating doses or milk ladder, starting with baked milk…
- Trial name
- NCT05960045
- Testing
- Direct Milk antigen reintroduction, Milk ladder
- Where
- Egypt
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Food Allergy in Children, Cow Milk Allergy
Nutrition Sufficiency, Allergy Efficacy and Safety of Neocate Jr in Children With Food Protein Allergy
The main purpose of this study is to evaluate efficacy and safety of an amino acid-based formula Neocate Jr in children with food protein allergy, and to evaluate nutrition sufficiency of Neocate Jr in 1 to 10 years old children…
- Trial name
- NCT05406141
- Testing
- Amino acid formula (Neocate Jr)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Cow's Milk Allergy
Validity of Cow's Milk-related Symptom Score Among Children Suspected to Have Cow's Milk Protein Alergy
Cow's milk protein allergy is a sensitivity reaction against cow's milk protein and and is calcified as IgE-medaited, non- IgE mediated and mixed type according to the underlying immunological mechanism.
- Trial name
- NCT05883384
- Testing
- stool analysis , CBC, specific IgE FOR Cow milk protein allergy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Cow's Milk Allergy
Diagnosis of Cow's Milk Protein Allergy
The study will assess the diagnosis of cow's milk protein allergy (CMPA) among infant and children in assiut university children hospital using skin prick test and specific serum IgE as well as their management.
- Trial name
- NCT04330092
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Food Allergy
The Effect of Per Oral Immunotherapy in Severe IgE Mediated Egg, Milk, and Nut Allergy in Adults
In Finland, the estimated prevalence of physician-diagnosed food allergy in 1-4 year old children is 9%, and the most common allergen is milk. The overall food allergy has been reported to be 3.7%.
- Trial name
- NCT01822353
- Testing
- Dietary supplement
- Where
- Finland
- Volunteers
- 23 people
- Sponsor
- Helsinki University Central Hospital
Cow Milk Allergy
Diagnosis of Cow's Milk Protein Allergy Among Infants and Children in Assuit University Children Hospital
The study will assess the diagnosis of Cow's milk protein allergy (CMPA) among infant and children in Assiut University Children Hospital using skin prick test and specific serum IgE
- Trial name
- NCT03456479
- Testing
- skin prick test - specific serum IgE
- Volunteers
- 30 people
- Sponsor
- Assiut University
Cow's Milk Allergy
Effect of Therapy With Aminoacid Based Formula Versus Hydrolyzed Whey Proteins in Children With Cow's Milk Allergy
Cow's milk allergy is an immunologically mediated adverse reaction to milk proteins. In industrialized countries there is an incidence of 2-3% in children younger than 2 years.
- Trial name
- NCT02379598
- Testing
- Aminoacid based formula, Hydrolyzed whey formula
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Federico II University
Allergy
Althera® Versus Nutramigen / Cow's Milk Intolerance
The primary objective of this study is to demonstrate that ALTHERA® is equal or superior in efficacy than NUTRAMIGEN®
- Trial name
- NCT01727115
- Testing
- Infant Formula Feeding
- Where
- 14 sites in Belgium
- Volunteers
- 116 people
- Sponsor
- Société des Produits Nestlé (SPN)