Clinical trials: CIPN - Chemotherapy-Induced Peripheral Neuropathy
Adenocarcinoma of Pancreas
Hand Therapy Intervention Versus Traditional Occupational Therapy to Prevent Chemotherapy Induced Peripheral Neuropathy
A pilot randomized feasibility trial with a blinded evaluator.
- Trial name
- NCT05374876
- Testing
- Hand Therapy Until CIPN, Traditional Occupational Therapy (TOT)
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- HonorHealth Research Institute
Chemotherapy-induced Peripheral Neuropathy
CIPN and it's Impact on Quality of Life in Patients Receiving Platinum and Taxanes
Neuropathies are a major cause of moderate to severe impairments in cancer patients. Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most frequent side effects caused by antineoplastic agents, with a prevalence…
- Trial name
- NCT05829967
- Volunteers
- 60 people
- Sponsor
- Assiut University
Cancer Patients, Chemotherapy-Induced Peripheral Neuropathy
Exercise and Mindfulness Intervention for Chemotherapy-Induced Peripheral Neuropathy in Patients With Cancer
The goal of this clinical trial is to learn whether an exercise- and mindfulness-based cognitive therapy intervention can improve physical and psychological symptoms in cancer patients with chemotherapy-induced peripheral…
- Conditions
- Cancer Patients, Chemotherapy-Induced Peripheral Neuropathy, Exercise Intervention
- Trial name
- NCT07556965
- Testing
- Exercise and Mindfulness
- Where
- 2 sites in China
- Volunteers
- 41 people
- Sponsor
- Nanjing Medical University
Cancer, Lung, Colon Neoplasm
Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients
This study aims to find out whether certain molecules in the blood, called microRNAs, are linked to how often and how severely people develop nerve damage from chemotherapy.
- Conditions
- Cancer, Lung, Colon Neoplasm, Neuropathy;Peripheral
- Trial name
- miR-CIPN#1 (NCT07427537)
- Testing
- Assessment of blood concentrations of microRNAs, Chemotherapy-induced peripheral neuropathy (CIPN) - grade, Pain assessement
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
CIPN - Chemotherapy-Induced Peripheral Neuropathy
The CONTRoL Trial: Cryotherapy vs. cOmpression Neuropathy TRiaL
The primary objective of this study is to select the best intervention from cold therapy, compression therapy and placebo at reducing neuropathic pain as measured by the change in the Neurotoxicity (NTX) component of the…
- Trial name
- CONTRoL (NCT03873272)
- Testing
- Cryotherapy, Compression Therapy, Loose glove/sock
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- Columbia University
Breast Cancer, Peripheral Neuropathies
Chemotherapy-Induced Peripheral Neuropathy-Essential Oil Intervention
This study will evaluate an oil blend with active ingredients for the reduction in chemotherapy-induced peripheral neuropathy in people with breast cancer.
- Trial name
- CIPN-EOI (NCT03449303)
- Testing
- EOI
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Augusta University
Cancer
Efficacy of Cryotherapy in Managing Chemotherapy-Induced Peripheral Neuropathy in Children With Leukemia
This study aimed to assess the efficacy of cryotherapy in controlling Peripheral Neuropathy in cancer children
- Trial name
- NCT06543264
- Testing
- Cryotherapy
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Delta University for Science and Technology
Chemotherapy-induced Peripheral Neuropathy (CIPN)
Trial of a Virtual Exercise-based Rehabilitation Program to Treat Persistent Chemotherapy-Induced Peripheral Neuropathy (CIPN)
The purpose of this study is to determine the effectiveness of the EX-CIPN program in reducing the strength of CIPN symptoms and CIPN-related disability and improving the ability to complete everyday activities.
- Trial name
- EX-CIPN (NCT07481149)
- Testing
- EX-CIPN
- Where
- Canada
- Volunteers
- 240 people
- Sponsor
- University Health Network, Toronto
Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy
Lidocaine Versus Duloxetine for the Prevention of Taxane-Induced Peripheral Neuropathy In Breast Cancer Patients
The aim of the study is to evaluate the effect of intravenous (IV) lidocaine versus oral duloxetine on the onset and severity of TIPN in patient with breast cancer as well as evaluation of Patients' quality of life and estimation…
- Conditions
- Peripheral Neuropathy, Chemotherapy-induced Peripheral Neuropathy, Breast Cancer
- Trial name
- TIPN (NCT04732455)
- Testing
- Lidocaine in Saline, Duloxetine 30 MG, Normal saline
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Gamal Mohamed Taha Abouelmagd
Breast Cancer Female, Chemotherapy-induced Peripheral Neuropathy
Home-Based Physical Activity Intervention for Taxane-Induced CIPN
This two-group, randomized control trial (RCT) will test the effects of a home-based, 16 week gait/balance training plus resistance (exercise bands) exercise program as compared to an educational cancer survivorship attention…
- Conditions
- Breast Cancer Female, Chemotherapy-induced Peripheral Neuropathy, Gait Disorders, Neurologic, Balance; Distorted
- Trial name
- B-HAPI (NCT04621721)
- Testing
- Gait/balance & resistive exercise
- Where
- United States
- Volunteers
- 312 people
- Sponsor
- University of South Florida
Chemotherapy-Induced Peripheral Neuropathy, Malignant Neoplasm
Transcranial Direct Current Stimulation in Reducing Pain in Cancer Patients With Chemotherapy Induced Peripheral Neuropathy
This early phase I trial studies how well transcranial direct current stimulation works in reducing pain in cancer patients with chemotherapy induced peripheral neuropathy.
- Trial name
- NCT04135326
- Testing
- Quality-of-Life Assessment, Questionnaire Administration, Transcranial Direct Current Stimulation
- Where
- United States
- Sponsor
- M.D. Anderson Cancer Center
Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
The main objective of this clinical trial is to evaluate the effectiveness and cost-effectiveness of adding ozone therapy to the clinical management of patients with pain secondary to chemotherapy-induced peripheral neuropathy
- Conditions
- Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic, Pain Syndrome
- Trial name
- O3NPIQ (NCT04299893)
- Testing
- Ozone, Oxygen
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Bernardino Clavo, MD, PhD
Breast Cancer, Peripheral Neuropathy
Yoga for Symptoms of Nerve Damage Caused by Chemotherapy
Some types of chemotherapy used to treat breast cancer can cause damage to nerves with symptoms like tingling, numbness, muscle weakness, and pain in the hands and feet that can last and can affect functioning.
- Conditions
- Breast Cancer, Peripheral Neuropathy, Gynecologic Cancer
- Trial name
- NCT03292328
- Testing
- Yoga, Wait List Control
- Where
- 2 sites in United States
- Volunteers
- 51 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer
PBMT for the Prevention of CIPN
ne of the most common cancers in women worldwide is breast cancer. A common used therapy in early-stage and metastatic breast cancer involves chemotherapy.
- Trial name
- NCT03391271
- Testing
- photobiomodulation therapy (PBMT)
- Where
- Belgium
- Volunteers
- 53 people
- Sponsor
- Hasselt University
Chemotherapy-induced Peripheral Neuropathy, CIPN - Chemotherapy-Induced Peripheral Neuropathy
Scrambler Therapy for Chemotherapy-Induced Peripheral Neuropathy
This research study is for people who have a condition called chemotherapy-induced peripheral neuropathy (CIPN). This condition develops as a result of receiving medication(s) to treat cancer, particularly chemotherapy.
- Trial name
- NCT07219472
- Testing
- Scrambler Therapy
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Case Comprehensive Cancer Center
Neuropathy;Peripheral, Chemotherapy-induced Peripheral Neuropathy
Voxx Human Performance Technology Socks for Chemotherapy-Induced Peripheral Neuropathy
This is a double blind, randomized, crossover pilot study of Voxx Human Performance Technology Socks versus placebo socks for the treatment of chemotherapy-induced peripheral neuropathy in patients with cancer.
- Conditions
- Neuropathy;Peripheral, Chemotherapy-induced Peripheral Neuropathy, Neuropathy
- Trial name
- NCT04403802
- Testing
- Voxx Human Performance Technology Socks
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Arash Asher, MD
Chemotherapy-induced Peripheral Neuropathy, Plasma Cell Myeloma
Cryocompression Therapy for Peripheral Neuropathy in Patients With Multiple Myeloma
This trial studies how well cryocompression therapy works in reducing bortezomib-induced peripheral neuropathy in patients with multiple myeloma.
- Trial name
- NCT03870451
- Testing
- VascuTherm5 vascular compression device
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Wake Forest University Health Sciences
Peripheral Neuropathy
Effect of Hands and Feet Exercises on Taxane Based Chemotherapy Induced Peripheral Neuropathy in Patients With Solid Tumors
The goal of this clinical trial is to determine whether hand and foot exercises can reduce the severity of Taxane-based chemotherapy-induced peripheral neuropathy (CIPN) in adult cancer patients aged 20-60 years who have Grade 1I…
- Trial name
- NCT07321236
- Testing
- Structured Hand and Foot Exercises
- Volunteers
- 58 people
- Sponsor
- University of Health Sciences Lahore
Anatomic Stage IV Breast Cancer AJCC v8, Chemotherapy-Induced Peripheral Neuropathy
Finding an Effective Dose of GM1 to Reduce or Prevent Neuropathy (Numbness or Weakness) Due to Treatment With Paclitaxel
This early phase/phase II trial tests the safety, side effects, and best dose of monosialotetrahexosylganglioside (GM1) and whether it works in reducing or preventing chemotherapy-induced peripheral neuropathy (CIPN) in patients…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Chemotherapy-Induced Peripheral Neuropathy, Metastatic Breast Carcinoma
- Trial name
- NCT05751668
- Testing
- Paclitaxel, Monosialotetrahexosylganglioside, Questionnaire Administration
- Where
- 33 sites in United States
- Volunteers
- 7 people
- Sponsor
- Alliance for Clinical Trials in Oncology
CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy
The Influence of Chemotherapy on Position Sense
Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most prevalent side-effects of chemotherapy, causing sensory and motor symptoms in patients.
- Conditions
- CIPN - Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy, Chemotherapy-Induced Peripheral Neuropathy in Breast Cancer
- Trial name
- ProprioCIPN (NCT07367711)
- Testing
- Questionnaire - Edinburgh Handedness Assessment, Questionnaire - QuickDash, Questionnaire - EORTC QLQ-CIPN20
- Where
- Belgium
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- KU Leuven