Clinical trials: CHIP
Covid19
Large-scale COVID-19 Population Screening
Infectious diseases pose a threat to the life of individuals worldwide. The pandemic has highlighted the need to develop an innovative and cost- effective large population-based screening methodology.
- Trial name
- NCT04847804
- Where
- 3 sites in Hong Kong
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hong Kong University of Science and Technology
Tuberculosis Infection, Tuberculosis Prevention
Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial
This qualitative study is designed to elicit the perspectives of relevant stakeholders to adapt a community-based TB/HIV intervention aimed on providing home-based TB prevention treatment (TPT) initiation for child TB contacts…
- Trial name
- NCT04494516
- Where
- 2 sites in Ethiopia, South Africa
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cardiovascular Diseases, Diabetes Mellitus
Retrospective Evaluation of Athens Complete Health Improvement Program (CHIP) Database
Data from participants in Athens CHIP classes from May 2011 to present will be analyzed to evaluate the differences in outcomes based on: 1) gender, 2) age, 3) whether a household member participated in the class with them.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias
- Trial name
- NCT03025451
- Testing
- The Complete Health Improvement Program
- Where
- United States
- Volunteers
- 512 people, healthy volunteers welcome
- Sponsor
- Ohio University
Consumer Behavior, Consumer Preference
Impact of Chip Thickness and Size on Eating Responses
To analyze prototypes developed with the base and seasonings of products that exhibit variations in chip thickness and size. The information obtained from this analysis will serve as the basis for subsequent research to explore…
- Conditions
- Consumer Behavior, Consumer Preference, Consumer Satisfaction
- Trial name
- NCT06691958
- Testing
- Tortilla corn chips 4-5 pieces, eat one piece at time, Tortilla corn chips 90 grams, Extruded corn chips 90 grams
- Where
- United Kingdom
- Volunteers
- 178 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Injury in the Home
Cincinnati Home Injury Prevention Study
One aim of this study is to test the efficacy of the installation of multiple, passive measures to reduce exposure to injury hazards in the homes of young children of first-time mothers and reduce childhood injury.
- Trial name
- CHIP (NCT01327092)
- Testing
- Injury Intervention Group
- Where
- United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
ST-elevation Myocardial Infarction (STEMI), Clonal Hematopoiesis of Indeterminate Potential (CHIP)
Clonal Hematopoiesis of Indeterminate Potential and Infarct Severity in ST-Elevation Myocardial Infarction
Clonal Hematopoiesis of Indeterminate Potential (CHIP) refers to the age-related expansion of hematopoietic stem cell clones carrying somatic mutations in leukemia-associated driver genes (e.g., DNMT3A, TET2, ASXL1) in the…
- Trial name
- CHIP in STEMI (NCT07615023)
- Testing
- Clonal hematopoiesis assessment and cardiac magnetic resonance imaging
- Where
- Austria
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Platelet Dysfunction, Von Willebrand Diseases
Clinical Performance Evaluation of T-TAS 01 PL Chip
This study will measure primary hemostatic ability using the T-TAS 01 System with PL chip, with a comparison to clinical truth.
- Conditions
- Platelet Dysfunction, Von Willebrand Diseases, Healthy, Congenital Platelets Abnormality
- Trial name
- NCT03621020
- Testing
- T-TAS 01 PL Chip, PFA-100 Col/Epi and Col/ADP
- Where
- 6 sites in United States, France
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Hikari Dx, Inc.
Cervical Cancer
Lab-on-a-chip Detection of Cervical Cancer Tumour Markers
This study aims to establish whether tumour markers measured from cytological samples can improve cervical cancer detection both prior to treatment and after treatment during follow up.
- Trial name
- MODULAR (NCT03380741)
- Testing
- Tumour markers detection
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Royal Marsden NHS Foundation Trust
Sensory
Impact of Crisp Hardness and Thickness on Eating Behaviour
To analyse texturally altered crisp products that exhibit variations in hardness and thickness. The aim is to generate knowledge on how these properties influence eating behaviour (number of chews, rate of consumption, etc.)…
- Trial name
- NCT07592949
- Testing
- Snack food
- Where
- United Kingdom
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D
Infertility
Microfluidic Chip Method Versus Density Gradient Centrifugation Method on Semen Parameters
Infertility affects many couples, with male infertility being a common cause. In vitro fertilization (IVF) is an effective treatment, but its success rates are not high.
- Trial name
- NCT05978947
- Testing
- ZyMōt Multi 850µL device, Density Gradient Centrifugation Method
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Professor Ernest Hung-Yu Ng
Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential
CHIP in Health and Disease
Clonal hematopoiesis (CH), including clonal hematopoiesis of indeterminate potential (CHIP), is an age-associated condition characterized by the expansion of hematopoietic stem and progenitor cell clones carrying acquired somatic…
- Conditions
- Clonal Hematopoiesis, Clonal Hematopoiesis of Indeterminate Potential, Clonal Cytopenia of Undetermined Significance (CCUS), Myelodysplastic Syndrome
- Trial name
- CHIP2 (NCT07780552)
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- VASCage GmbH
Alzheimer's Disease (AD), Neurodegenerative Disease
A Biomarker-chip Assay in Preserved Red Blood Cells for the Diagnosis of Alzheimer's Disease
The ADCHIP study (ST0067) is a non-interventional, monocentric, prospective study conducted by Amoneta Diagnostics and the Leenaards Memory Center (Lausanne, Switzerland).
- Conditions
- Alzheimer's Disease (AD), Neurodegenerative Disease, Dementia, Frontotemporal Dementia (FTD)
- Trial name
- ADCHIP (NCT07307872)
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Amoneta Diagnostics SAS
Cerebrovascular Disease, Stroke
Genetic Studies to Identify Stroke Subtypes and Outcome
This study will characterize the gene response of the body's immune and inflammatory cells to stroke. There is a wide variation in stroke risk, stroke outcome, and response to clot-busting therapy for stroke.
- Trial name
- NCT00357513
- Where
- 3 sites in United States
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Uninsured Children Eligible for Medicaid or CHIP
A Randomized Trial of Effects of Parent Mentors on Insuring Minority Children
The Kids' HELP trial rigorously documented that a Parent Mentor intervention results in multiple benefits: more children are insured faster, children's access to healthcare and parental satisfaction improve, quality of well-child…
- Trial name
- NCT01264718
- Testing
- Parent Mentors
- Where
- 2 sites in United States
- Volunteers
- 329 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Thrombocytopenia
Clinical Performance Evaluation of T-TAS®01 HD Chip
The study is being conducted to validate the clinical performance of the T-TAS 01 HD assay for measurement of thrombogenicity in patients with thrombocytopenia receiving a platelet transfusion.
- Trial name
- NCT06087198
- Testing
- T-TAS 01 HD Assay
- Where
- 6 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Hikari Dx, Inc.
COVID 19
Bio-reconfigurable Electronic Platform for Multiplex Detection of Viral Respiratory Pathogens
This project focuses on developing a cutting-edge electronic biosensor platform for highly sensitive and specific detection of target biomolecules, with initial applications targeting SARS-CoV-2 detection.
- Trial name
- BIOPLEX (NCT06702540)
- Testing
- Biosensor chip
- Where
- Italy
- Volunteers
- 158 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Sickle Cell Disease
Sickle Cell Disease Biofluid Chip Technology (SCD BioChip)
'Sickle-shaped' anemia was first clinically described in the US in 1910, and the mutated heritable sickle hemoglobin molecule was identified in 1949.
- Trial name
- NCT02824471
- Testing
- SCD Group
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospitals Cleveland Medical Center
Cardiovascular Diseases, Diabetes Mellitus
Complete Health Improvement Program (CHIP) Risk Reduction/Claims Evaluation Project
The project proposes to provide the Complete Health Improvement Program (CHIP) initially up to 25 adult (non-pregnant) Ohio University employees (and/ or their adult family members) with with diabetes / prediabetes, obesity /…
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Hypertension, Dyslipidemias
- Trial name
- NCT02977884
- Testing
- The Complete Health Improvement Program
- Where
- United States
- Volunteers
- 389 people, healthy volunteers welcome
- Sponsor
- Ohio University
Genetics, Population
Population Genomic Diversity of France
Having access to DNA sequences from individuals that share common ancestry with patients is of interest when analysing individual genomes for diagnoses.
- Trial name
- POPGEN (NCT04183023)
- Testing
- Collection of a salivary sample
- Where
- France
- Volunteers
- 10,250 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
To Investigate the Effect of CHIP on Renal Insufficiency in AMI Patients
Clonal Hematopoiesis on Prognosis in Patients With Myocardial Infarction
This is an observational study without intervention. It is planned to include 500 patients with AMI from October 2023 to July 2026.The study was divided into three parts.
- Trial name
- NCT06156319
- Testing
- No intervention
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Yang Jing