Clinical trials: CGA
Older People, Non-Communicable Chronic Diseases
A Personalized Prevention Program (PPP) Based on the Comprehensive Geriatric Assessment (CGA) for the Prevention of Multidimensional Frailty Related to Non-communicable Chronic Diseases (NCDs) in Older People
Non-Communicable Diseases (NCDs) can accelerated the aging process and increase the frailty condition The Comprehensive Geriatric Assessment (CGA) is the gold standard in the geriatric clinical context Recently, in Italy the…
- Trial name
- PrimaCare_P3 (NCT06224556)
- Testing
- Brief-MPI assessment (based on the Comprehensive Geriatric Assessment); Personalized Prevention Program
- Where
- 4 sites in Italy
- Volunteers
- 1,216 people
- Sponsor
- Alberto Pilotto
Gastric Cancer
Frailty Assessment and Intervention in Elderly Patients with Gastric Cancer Receiving Gastrectomy and Adjuvant Chemotherapy
Gastric cancer ranks among the top ten leading causes of death in Taiwan. Radical surgery is the sole curative method for gastric cancer.
- Trial name
- NCT06055387
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 300 people
- Sponsor
- Chang Gung Memorial Hospital
Health Services for the Aged, Frailty
e-GAB: Electronic Geriatric Assessment Bundle: Development of an Arabic Self-administered Android CGA Application
The aim of this study is to design and assess the accuracy of administering the electronic Geriatric Assessment Bundle (e-GAB) compared to geriatrician performed comprehensive geriatric assessment (CGA) in a group of Egyptian…
- Conditions
- Health Services for the Aged, Frailty, Cognitive Impairment, Depression
- Trial name
- NCT04211285
- Testing
- e-GAB, standard physician performed CGA
- Where
- Egypt
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Drug Use
E-learning to Improve the Quality of Drug Prescribing in Hospitalized Elderly Patients
This randomized controlled pragmatic study is aimed to set-up, assess and implement an integrated e-learning program of medical education in an hospital setting, focused on teaching and implementing CGA added to geriatric…
- Trial name
- NCT02339792
- Testing
- E-learning
- Volunteers
- 697 people, healthy volunteers welcome
- Sponsor
- Mario Negri Institute for Pharmacological Research
GI Cancer
Effect of Geriatric Intervention in Frail Patients with Gastric, Biliary, and Pancreatic Cancer Receiving Palliative Chemotherapy
Gastric, biliary and pancreatic cancer are commonly malignancies from gastro- intestinal tract in Taiwan. Because lack of specific symptoms at presentation and effective screening methodology, majority of these patients are…
- Trial name
- NCT06040801
- Testing
- Frailty intervention measures
- Where
- Taiwan
- Volunteers
- 138 people
- Sponsor
- Chang Gung Memorial Hospital
Cancer, Frailty
G8 Screening Tool Validation in Older Adults With Cancer in Portugal
The G8 screening tool is widely recommended for the identification of frailty in older adults with cancer. However, prospective validation data in the Portuguese population are currently lacking.
- Conditions
- Cancer, Frailty, Aged
- Trial name
- G8-PT (NCT07487298)
- Testing
- G8 Screening Tool, Comprehensive Geriatric Assessment
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Hospital de Braga
Atrial Fibrillation
The European Registry of Older Subjects With Atrial Fibrillation (EUROSAF)
Preliminary data suggest that: 1. a different risk of mortality, as assessed by the Multidimensional Prognostic Indices (MPI), may influence the anticoagulant prescription in older subjects with Atrial Fibrillation (AF); 2.
- Trial name
- EUROSAF (NCT02973984)
- Where
- Italy
- Volunteers
- 3,000 people
- Sponsor
- Alberto Pilotto
Multiple Myeloma, Comprehensive Geriatric Assessment
cGA in Newly-diagnosed Elderly MM Patients: a Multi-center, Prospective, Non-interventional Study.
This is a multi-center, prospective, non-interventional study. Eligible newly diagnosed elderly multiple myeloma (MM) patients will receive comprehensive geriatric assessment (cGA) including ECOG scale, questionaires of…
- Trial name
- NCT03122327
- Testing
- Questionaires
- Volunteers
- 200 people
- Sponsor
- Peking Union Medical College Hospital
Diffuse Large B-cells Non-Hodgkin Lymphoma
A Phase II Study of the FIL on Elderly Frail Patients With DLBCL
A phase II study to evaluate the combination of Lenalidomide and Rituximab as front line therapy for the treatment of elderly frail patients evaluated in CGA with Diffuse Large B-cells non-Hodgkin Lymphoma.
- Trial name
- NCT02955823
- Testing
- Rituximab-Dexamethasone-Lenalidomide
- Where
- 18 sites in Italy
- Volunteers
- 68 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Non-small Cell Lung Cancer, Stereotactic Body Radiotherapy
LIVELUNG - Impact of CGA in Patients Diagnosed With Localized NSCLC Treated With SBRT
Older patients with non-small cell lung cancer (NSCLC) treated with stereotactic body radiation therapy (SBRT) often die from other causes than lung cancer due to age-related comorbidities.
- Conditions
- Non-small Cell Lung Cancer, Stereotactic Body Radiotherapy, Comprehensive Geriatric Assessment
- Trial name
- LIVELUNG (NCT05919641)
- Testing
- Comprehensive Geriatric Assessment
- Where
- 4 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Odense University Hospital
Cancer
A Geriatric Assessment Intervention for Older Cancer Patients Receiving Chemotherapy
The purpose of this study is to determine whether information regarding GA and GA-driven interventions improves outcomes in older cancer patients receiving first-line or second-line chemotherapy by comparing rates of chemotherapy…
- Trial name
- NCT01915056
- Testing
- GA-driven Intervention
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- University of Rochester
Periodontal Diseases, Pregnancy Gingivitis
Stress and Gingival Inflammation in Non-pregnant and Pregnant Women
Background: The purpose of the present study is to research whether stress scale scores alter with relationship to gingival inflammation and examine the impact of non-surgical periodontal therapy during pregnancy on the levels of…
- Trial name
- NCT03336957
- Testing
- periodontal treatment
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Systemic Sclerosis
Catestatin as a Novel Biomarker for Cardiovascular and Microvascular Involvement in Systemic Sclerosis
This study investigates the relationship between serum catestatin levels and systemic sclerosis (SSc), with a focus on cardiovascular involvement and microvascular alterations, to determine catestatin's potential as a biomarker…
- Trial name
- NCT07209644
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Type 2 Diabetes
The Effects of Specialty Coffee on Cognitive Function in People With Type 2 Diabetes
Coffee has been found to have beneficial effects on cognitive function and blood sugar control. Benefits include reduced risk of cognitive decline and improved performance on cognitive tests, as well as reduced risk of diabetes…
- Trial name
- NCT05709847
- Testing
- Coffee
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Reading
Aortic Valve Stenosis
CGA-TAVI Registry to Evaluate the Predictive Value of a CGA in Predicting TAVI Outcomes
Registry study to evaluate the predictive value of a comprehensive geriatric assessment with regard to the outcome of a transcatheter aortic valve Implantation.
- Trial name
- CGA-TAVI (NCT01991444)
- Testing
- TAVI
- Where
- 3 sites in Canada, Italy and 1 more
- Volunteers
- 72 people
- Sponsor
- Institut für Pharmakologie und Präventive Medizin
CGA, Comprehensive Geriatric Assessment
Exploring the User Experience of CGA-Q
As people become older they may start to have more than one health issue at one time. Geriatricians are doctors who specialise in looking after older people.
- Conditions
- CGA, Comprehensive Geriatric Assessment, Person Centred Care, Frailty
- Trial name
- NCT06646575
- Testing
- Qualitative data, no intervention
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Geriatrics, Comprehensive Geriatric Assessment
Effectiveness of CGA on QoL in Older Patients With Cancer Receiving Systemic Therapy
The G-oncoCOACH study aims to evaluate the effectiveness of the Comprehensive Geriatric Assessment (CGA) process coordinated by a geriatric team in combination with intensive patient coaching compared to the current standard of…
- Trial name
- G-oncoCOACH (NCT04069962)
- Testing
- CGA coordination by geriatric team including intensive patient coaching and follow-up
- Where
- Belgium
- Volunteers
- 204 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Diabetic Kidney Disease
Diagnostic Value of Serum Cathepsin S and Chromogranin A in DKD
1. Evulate the diagnostic value of serum cathepsin S and chromogranin A for Diabetic kidney disease. 2. To correlate the levels of serum Cathepsin S and chromogranin A with HbA1c and eGFR in type 2 diabetic patients based on…
- Trial name
- NCT06069076
- Testing
- cathepsin S and chromogranin A
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Assiut University
Early Release of Chromogranin A (CgA)
Predictive Value of Early Changes of Chromogranin A Levels in Patients With Neuroendocrine Tumours Treated With PRRT
The results of the study suggest that an early change in CgA levels might serve as a prognostic factor in NET patients treated with PRRT.
- Trial name
- NCT06183047
- Testing
- early release of chromogranin A (CgA) in patients with neuroendocrine tumours (NET) treated with peptide receptor radionuclide therapy (PRRT).
- Volunteers
- 38 people
- Sponsor
- Military Institute od Medicine National Research Institute
Surgery, Geriatric Assessment
Implementation Pilot of Preoperative CGA Before Major Surgery
The goal of this clinical trial is to test whether a new implementation package can help older adults prepare for major surgery.
- Conditions
- Surgery, Geriatric Assessment, Health Services Research, Implementation Science
- Trial name
- NCT06184724
- Testing
- Implementation Package for CGA, Routine Clinical Care
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison