Clinical trials: Burns
Burns
Effect of Music Therapy on Families of Burn Patients
The purpose of this study is to investigate the efficacy of music therapy in assisting with the coping and adjustment of children of adults with major burns.
- Trial name
- MTS3 (NCT00824681)
- Testing
- Sound Of Family Together (S.O.F.T.) Music Program, Non-Therapy Related Activities (NTRA)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- MetroHealth Medical Center
Treatment of Donor Site Burns
Multi-Center, Prospective, Randomized, Comparison of AWBAT™-D vs. Xeroform™ or Glucan II™ for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to compare the rate of healing and the non-adherence of three types of dressings. The study will also compare rate of infection, scarring and perception of pain associated with treatment.
- Trial name
- AWBAT-D (NCT00964470)
- Testing
- AWBAT™-D and XEROFORM™ OR GLUCAN II™ dressings
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Burn Surgery
Comparison of AWBAT™-D and MEPILEX® AG for Treatment of Donor Sites in Burn Surgery
The purpose of this study is to examine AWBAT™-D compared to Mepilex® Ag for the treatment of donor sites in burn surgery.
- Trial name
- NCT00974597
- Testing
- AWBAT™-D and Mepilex® Ag dressings
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aubrey Inc.
Hot Water Burns (Scalds)
Health and Environmental Effects of Boiler Management Systems in Social Housing
The purpose of this study is to evaluate the impact of a passive safety measure, namely a reduction in centrally controlled hot tap water temperatures in social housing using a boiler management system, as an effective public…
- Trial name
- NCT00874692
- Testing
- BMS and sterilisation programme
- Where
- United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Burn
Comparing the Use of Vitamin c (Ascorbic Acid) in Eye Burn in Subconjunctival Injection to Topical or Oral Treatment.
Eye burns may cause a severe permanent damage. One kind of treatment is the use of vitamin C (Ascorbic acid). This study will compare between subconjunctival topical and/or systemic route of administration and topical and/or…
- Trial name
- NCT00734695
- Testing
- vitamin c
- Where
- 2 sites in Israel
- Volunteers
- 20 people
- Sponsor
- The Baruch Padeh Medical Center, Poriya
Burns, Insulin Resistance
Substrate Cycling in Energy Metabolism
Insulin resistance and hyperglycemia contribute to negative outcomes in burned patients. We will assess insulin sensitivity in traditional terms of glucose metabolism, and with regard to the responsiveness of both muscle and…
- Trial name
- NCT00361751
- Testing
- fenofibrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Burns
Efficacy and Tolerance of Cellularised LG002 Versus Uncellularised LG002 in the Treatment of Severe Burns Injuries
After severe burn injury, the full-thickness burn areas are excised (in the first week) and then temporarily covered with allograft (cryogenic preserved cadaver skin).
- Trial name
- NCT00366041
- Testing
- Dermal substrate cellularised LG002 (10x10cm), Dermal substrate uncellularised LG002 (10x10 cm)
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- Laboratoires Genévrier
Burns, Bacterial Infections
Ciprofloxacin on Burned Patients
This was a non randomised, multi center, italian study performed in burn patients receiving an antibiotic (ciprofloxacin) in order to treat an active infection.
- Trial name
- NCT00668044
- Testing
- Ciprofloxacin (BAYO9867)
- Where
- 7 sites in Italy
- Volunteers
- 18 people
- Sponsor
- Bayer
Burn Wound
Clinical Efficacy and Safety of Autologous Cultured Keratinocyte Cell on Severe Burn Wood
The efficacy and safety of Autologous cultured keratinocyte cell on severe burn wound.
- Trial name
- keratinocyte (NCT00978705)
- Testing
- Autologous cultured keratinocyte cell
- Where
- South Korea
- Volunteers
- 19 people
- Sponsor
- Biosolution Co., Ltd.
Burn, Trauma
Trial of Zesteem (Estradiol) in Healing of Split Thickness Skin Graft Donor Sites
This trial will assess the effects of Zesteem (estradiol) on the healing of split thickness skin graft donor sites in patients aged 18-85 years.
- Conditions
- Burn, Trauma, Varicose Ulcer
- Trial name
- NCT00426972
- Testing
- estradiol (Zesteem)
- Where
- 30 sites in Germany, Latvia and 2 more
- Volunteers
- 148 people
- Sponsor
- Renovo
Burns
Study of Arginine Metabolism and Nitric Oxide Formation in Relation to Glutamine Supply in Severely Burned Patients
The purpose of the study is to understand the way the body uses amino acids and proteins in burned patient during the time they cannot eat normally.
- Trial name
- NCT00216970
- Testing
- Alteration in nutritional support
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts General Hospital
Burn
Alterations in Protein Synthesis Rates of Burn Patients Measured Over Time Using PET Scans
Our specific aim is to gain an understanding of protein synthesis rates in burn patients at various times during their injury and recovery by using PET scans. This will be compared with healthy volunteer controls.
- Trial name
- NCT00253279
- Testing
- PET Scans
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Burns
The Effect of Two Versus Ten Days Application of Flammacerium in Partial Thickness Burns
The objective of the proposed study is to assess whether the application of flammacerium for 2 days is as good as, or even better than, the application of flammacerium for 10 days regarding woundhealing in partial thickness burns.
- Trial name
- NCT00156988
- Testing
- cerium nitrate-silver sulfadiazine (cerium-flamazine)
- Where
- Netherlands
- Sponsor
- Association of Dutch Burn Centres
Burns
Evaluation Of Linezolid Pk Profile In Burns Patients
Evaluation of linezolid pk profile in burns patients
- Trial name
- NCT00255996
- Testing
- linezolid
- Where
- 3 sites in France
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Burns, Shock
An Upgrading of the Resuscitative Patterns by Utilization of the Balanced Crystalloids and Synthetic Colloids and the Non-Invasive Hemodynamic Monitoring During Burn Shock
Fluid Therapy Lithium Dilution Cardiac Output (LIDCO) controlled trial in BURNS (FACT in BURNS) is a prospective randomized multicentric study.
- Trial name
- FACT in BURNS (NCT00914563)
- Testing
- LIDCO Lithium Dilution Cardiac Output, Standard Care
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Skin Graft
Effect of Platelet Rich Plasma and Keratinocyte Suspensions on Wound Healing
This prospective randomized trial evaluated the impact of autologous keratinocytes suspended in platelet concentrates on healing skin graft donor site wounds.
- Trial name
- NCT00856934
- Testing
- Autologous Platelet Rich Plasma, Keratinocyte suspension, Standard dressings
- Where
- Switzerland
- Volunteers
- 45 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Burns
Safety and Efficacy of I-020502 in Meshed Skin Autografting
This is a phase II, multi-centre, controlled study comparing the safety and tolerability on wound healing following an application of I-020502 in a concentration of 1μg/mL TG-PDGF.AB versus staples applied in the same patient to…
- Trial name
- NCT00471939
- Testing
- I-020502
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- Kuros Biosurgery AG
Acute Thermal Burns
The Effects of Hyperbaric Oxygen Therapy (HBOT) on Acute Thermal Burns
The blinded RCTstudy aims to: Determine the effects of HBOT on burns conversion for patients who have fresh thermal burns injury using the LDI.
- Trial name
- NCT00824551
- Testing
- Hyperbaric Oxygen Therapy, Standard care
- Where
- Singapore
- Volunteers
- 80 people
- Sponsor
- Singapore General Hospital
Pruritus, Itching
Evaluation of Post Burn Rehabilitation Population for Itch Control
Severe itching following burn injury is a common complication. As many as 87% of burn patients report severe itching. The intense itching can increase anxiety and can interfere with sleep and normal activities of daily living…
- Conditions
- Pruritus, Itching, Burn Pruritus
- Trial name
- NCT00782054
- Testing
- Provase, Control moisturizer
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Swiss-American Products, Inc
Eye Burns
The Role of Amniotic Membrane Transplantation in Ocular Chemical Burns
This is a randomized clinical trial study to identify the role of AMT (amniotic membrane transplantation) in treating epithelial defect, symblepharon prevention preventing corneal vascularization and opacity decreasing pain and…
- Trial name
- NCT00370812
- Testing
- amniotic membrane transplantation
- Where
- Iran
- Volunteers
- 90 people
- Sponsor
- Shahid Beheshti University of Medical Sciences