Clinical trials: Burn Shock
Burn Shock
Effect of Pre-emptive Intravenous Immunoglobulin (IVIG) on the Incidence of Septic Episodes in Pediatric Burn Patients
Effect of pre-emptive intravenous immunoglobulin administration on the incidence of septic episodes in pediatric burn patients: A randomized controlled study.
- Trial name
- NCT05134792
- Testing
- intravenous immunoglobulin
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Burns
Pilot Trial of Statin Use in Burn Patients
This is a 90 day study, with patients receiving either oral Rosuvastatin or placebo for up to 28 days. The study will assess the affect of statins administered soon after burn injury on C-reactive protein (CRP) levels, patient…
- Trial name
- BURNSTAT (NCT00978419)
- Testing
- Rosuvastatin
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Vanderbilt University Medical Center
Low Gelsolin, Trauma
Ascending Single Dose Study of Rhu-pGelsolin in Patients With Decreased Gelsolin Levels
This study is designed to assess the pharmacokinetics and safety of an infusion of a single dose of recombinant plasma gelsolin (rhu-pGelsolin) when given to patients admitted to the Intensive Care Unit with documented low levels…
- Conditions
- Low Gelsolin, Trauma, Infection, Burns
- Trial name
- NCT00671307
- Testing
- rhu-pGelsolin
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- Critical Biologics Corporation
Post Burn Cubital Tunnel Syndrome
Post Burn Cubital Tunnel Syndrome Electrophysioligical and Functional Responses to High Intensity Laser Therapy Versus Extracorperal Shock Wave Therapy.
Post-burn cubital tunnel syndrome is a disabling complication that may occur after upper-limb burns involving the elbow due to edema, scar formation, and tissue compression around the ulnar nerve.
- Trial name
- NCT07102992
- Testing
- High intensity laser therapy, Shock Wave therapy, Ulnar nerve gliding exercises.
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ahram Canadian University
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Multiple Organ Failure
Efficacy of Coenzyme Q10 Supplementation on Multi-Organ Dysfunction in Severely Burned Patients
This multi-center prospective intervention study is designed to develop coenzyme Q10 (CoQ10) supplementation as a cost-effective adjunctive therapy for burn injury.
- Trial name
- NCT03968640
- Testing
- CoQ10
- Where
- United States
- Sponsor
- American Burn Association
Hand Burn, Carpal Tunnel Syndrome
Shock Wave on Pillar Pain After Carpal Tunnel Release in Hand Burn
"In burn cases, the reported causes of CTS are increased volume of carpal tunnel content due to edema and synovitis, wrist hyperextension, tight dressing, fibrosis, and direct burn to the nerve.
- Trial name
- NCT06371885
- Testing
- shock wave therapy, traditional physical therapy
- Where
- Egypt
- Volunteers
- 52 people
- Sponsor
- Cairo University
Shock, Thermal Burn
VItamin C in Thermal injuRY: The VICToRY Trial
This study aims to show that giving high dose, intravenous vitamin C in addition to standard care to burned critically ill patients will be associated with less organ dysfunction, improved survival and a quicker rate of recovery.
- Trial name
- VICToRY (NCT04138394)
- Testing
- Ascorbic Acid
- Where
- 33 sites in United States, Belgium and 7 more
- Volunteers
- 666 people
- Sponsor
- Clinical Evaluation Research Unit at Kingston General Hospital
Burn Injury
Efficacy of EPSW Plus HILT on Carpal Tunnel Syndrome Post Burn Injury
To study the effect of adding ESWT as a noninvasive short-term treatment plus high-level laser therapy for moderate carpal-tunnel syndrome post-burn injuries.
- Trial name
- NCT05876442
- Testing
- Extracorporeal Shock Wave Therapy., High Intensity Laser Therapy, Traditional Physical Therapy Exercise Program
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Cairo University
Burns, Trauma
Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Trial name
- NCT01922960
- Testing
- micro-imaging
- Where
- United States
- Sponsor
- University of South Alabama
Burns, Shock
The Acute Burn Resuscitation Multicenter Prospective Observational Trial
This is a prospective, non-interventional, observational study of consecutive burn patients admitted to 20 selected burn centers in North America.
- Trial name
- ABRUPT (NCT03144427)
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- American Burn Association
Trauma, Burns
Inflammation and the Host Response to Injury (Burns)
The purpose of this study is to help improve our understanding of the biology involved in the body's response to serious trauma or burn injury.
- Conditions
- Trauma, Burns, Multiple Organ Failure
- Trial name
- NCT00257244
- Where
- 4 sites in United States
- Volunteers
- 280 people
- Sponsor
- Massachusetts General Hospital
Hand-burned Children
Comparative Study Between Botulinum Toxin-A Injection and Shock Waves on Hypertrophic Scars in Hand-burned Children
PURPOSE: The study aims to compare study between Botulinum toxin-A injection and shock waves therapy on hypertrophic scars in hand-burned children.
- Trial name
- NCT06174155
- Testing
- physical therapy treatment, Botulinum toxin-A injection in addition to physical therapy program, shock wave therapy in addition to physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Burn Scar, Burns
Shock Wave Therapy Versus Conventional Physical Therapy for Partial- Thickness Forearm Burn Scars
Burn injuries can lead to significant physical and psychological challenges, particularly when they result in scarring. Burn scars can lead to a variety of complications that significantly impact a patient's quality of life1.
- Trial name
- NCT07234305
- Testing
- Shock wave, Traditional Physical Therapy
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- MTI University
Burns Shock
Study on Efficacy and Safety of Human Albumin in Burn Shock Recovery
To explore the effects and safety of human albumin in burn shock recovery, and then provide a theoretical basis for its rational use.
- Trial name
- NCT04928859
- Testing
- Albumin
- Volunteers
- 364 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Cicatrix, Hypertrophic
The Effect of Extracorporeal Shock Wave Therapy in the Treatment of Post Burn Scars
A prospective, randomized, controlled study. The patients were divided into two groups with twenty patients per group. The control group received the standard treatment for postburn scars.
- Trial name
- NCT04558944
- Testing
- Extracorporal Shock Wave Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Trauma, Burns
Inflammation and the Host Response to Injury (Trauma)
The purpose of this study is to help improve our understanding of the biology involved in the body's response to serious trauma or burn injury.
- Conditions
- Trauma, Burns, Multiple Organ Failure
- Trial name
- NCT00257231
- Where
- 4 sites in United States
- Volunteers
- 610 people
- Sponsor
- Massachusetts General Hospital
Burn Body Region Unspecified, Burn Shock
Enteral Resuscitation Nepal
Nepal and the South Asian sub-continent carry some of the highest rates of burn injury globally, with associated high morbidity and mortality.
- Trial name
- NCT05559489
- Testing
- Oral Rehydration Solution, Lactated Ringer
- Where
- Nepal
- Volunteers
- 240 people
- Sponsor
- Nepal Health Research Council
Inflammatory Response, Multi Organ Failure
Association of Cytokines With the Development of Complications in Burn and Toxic Epidermal Necrolysis (TENS) Patients
This study will involve blood draws to test for specific cytokines. The study goal is to gain a better understanding of the role of inflammatory response in the development of specific complications in burn and TENS patients.
- Conditions
- Inflammatory Response, Multi Organ Failure, Nosocomial Infection, Deep Vein Thrombosis
- Trial name
- NCT04252651
- Testing
- Blood Draw
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Joseph M. Still Research Foundation, Inc.
Burns, Sepsis
Comparison Between Interleukin 6 and Procalcitonin in Detecting Sepsis and Incidence of Mortality in Burn ICU Patients
The investigators will compare the efficacy of Interleukin-6 (IL-6) as a better indicator than procalcitonin in burn patients with sepsis or septic shock regarding success of treatment and early ICU discharge.
- Conditions
- Burns, Sepsis, Septic Shock, Death
- Trial name
- NCT06915974
- Testing
- Interleukin 6
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University