Clinical trials: Burn Pain
Dermatology
Comparative Clinical Trial on Neoviderm Skin Emulsion and Connettivi-na 0.2% Cream to Evaluate the Normalization Process of the Skin and Re-duction of Cutaneous Tension and Pain in Patients With Superficial Burns Grade 1 and 2
It is a single centre, randomized (set up or distributed in a deliberately random way), open-label (study participants and researchers both know which treatment the patient is receiving), prospective, interventional…
- Trial name
- NVD01/22 (NCT05805917)
- Testing
- Neoviderm Skin Emulsion medical device, Connettivina 0.2% Cream
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ganassini S.p.A. di Ricerche Biochimiche
Burns, Burn Wound
Virtual Reality Adjunct for Procedural Pain and Anxiety Management in Burn Wound Care
This randomized controlled trial is designed to evaluate the efficacy of immersive virtual reality (VR) as an adjunct to standard analgesia during dressing changes in adult burn patients.
- Conditions
- Burns, Burn Wound, Procedural Pain, Anxiety Acute
- Trial name
- VR-Burn (NCT06913270)
- Testing
- Immersive Virtual Reality Distraction (IVRD), Nature Video Distraction (NVD)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al Hayah University In Cairo
Pain Management, Burn Injury
Perioperative Lidocaine Infusions for the Management of Pain From Burn Injury
The purpose of this study is to find out if IV lidocaine infusion decreases the need of opioids, improves pain management, and reduces the risks of developing complications from prolonged opioid use in burn injury participants…
- Conditions
- Pain Management, Burn Injury, Lidocaine
- Trial name
- NCT06828601
- Testing
- IV Lidocaine, IV Saline
- Volunteers
- 20 people
- Sponsor
- University of Washington
Skin Transplantation, Pain
Topical Morphine for Analgesia in Patients With Skin Grafts
The management of pain endured by patients after skin grafting is complex. Pain is the single most distressing symptom but as it is difficult to manage, it is often under-treated.
- Trial name
- NCT00362219
- Testing
- Morphine - .25 mg, Morphine
- Where
- Israel
- Sponsor
- Rambam Health Care Campus
Burn Related Pain
Take Charge of Burn Pain
Persons with burn-related pain remain under treated and do not have access to comprehensive burn pain management. We seek to extend evidence-based cognitive behavioral pain management strategies to a group of burn survivors that…
- Trial name
- NCT02661724
- Testing
- TCBR-Pain
- Where
- United States
- Volunteers
- 137 people
- Sponsor
- Johns Hopkins University
Pain
Reduction in Pain Intensity Following IV or Oral Pain-relieving Products
The purpose of this study is to evaluate two experimental pain models to see if they would be useful for comparing different products for reduction in pain intensity.
- Trial name
- NCT02678416
- Testing
- IV Acetaminophen (Treatment A), Oral Acetaminophen (Treatment B), Morphine (Treatment D)
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Mallinckrodt
Pain, Anxiety
The Use of Clonidine in Pain and Anxiety Associated With Acute Burn Injury in Children
Some of the children who suffer acute burn injury do not have adequate pain and anxiety management with the current regimen of scheduled opiates (morphine) and benzodiazepines (lorazepam).
- Trial name
- clonidine (NCT00580151)
- Testing
- clonidine
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Burns
Novel Virtual Reality for Burn Wound Care Pain in Adolescents
Burn wounds cause intense, complex pain, and subsequent burn wound care causes further intense, episodic pain that is often unrelieved by opioid and non-opioid medications, resulting in under-treatment of pain.
- Trial name
- NCT03155607
- Testing
- Virtual Reality Distraction
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Arkansas
Burns
Virtual Reality on Pain and Range of Motion on Burn
The Purpose of the study is to determine the effect of virtual reality exercise on pain and shoulder range of motion in pediatrics with 2nd-degree anterior shoulder burn injuries.
- Trial name
- NCT05352711
- Testing
- active assisted exercise and with fully immersive Head-Mounted Display virtual reality ( Oculus Quest virtual reality (VR) headset with hand con, active assisted range of motion exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Pain
Reducing Brief Thermal and Electrical Pain (Four Study Days)
Ultimately, the purpose of the present study is to help improve pain control in burn patients during wound care and physical therapy, where pain levels with opioids alone are often excessively high.
- Trial name
- 4DO (NCT00682682)
- Testing
- Virtual Reality video distraction, Virtual Reality video game
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pain, Cancer
Extension Study of ACTIQ Treatment for Children and Adolescents With Breakthrough Pain
The objective of the study is to monitor the safety (adverse event data) of longer-term use of ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC]) treatment in children with pain associated with cancer, sickle cell disease, or…
- Conditions
- Pain, Cancer, Sickle Cell Anemia, Severe Burns
- Trial name
- NCT00236093
- Testing
- ACTIQ (Oral Transmucosal Fentanyl Citrate [OTFC])
- Where
- 28 sites in United States, Canada and 1 more
- Sponsor
- Cephalon
Hyperalgesia, Pain
Effect of High Dose Naloxone on Secondary Hyperalgesia
Recent studies have focused on the role of endogenous opioids on central sensitization. Central sensitization is known to be impaired or altered in chronic pain conditions, as fibromyalgia or chronic tension headache.
- Conditions
- Hyperalgesia, Pain, Naloxone, Opioid Antagonist
- Trial name
- NCT01935206
- Testing
- Naloxone (2 mg/kg)
- Where
- 2 sites in Denmark
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Burns, Laughter Yoga
The Effect of Laughter Yoga Practiced After Burn Dressing
Burn is a serious trauma that causes acute damage to the skin and subcutaneous tissues due to the effect of heat, electricity, radiation, physical, and chemical substances.
- Trial name
- laughteryoga (NCT06829745)
- Testing
- Laughter Yoga
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Saglik Bilimleri Universitesi
Partial-thickness Burn, Pain
Banana Leaves as a Wound Dressing for Partial Thickness Second Degree Burns in Adult Patients.
This study plans to look at the benefits of banana leaves as a primary burn wound dressing. Study patients will be compared to historical patients
- Conditions
- Partial-thickness Burn, Pain, Second Degree Burn
- Trial name
- NCT07453732
- Testing
- Banana leaf dressing
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Colorado, Denver
Capsaicin, Ultaviolet B Light Burn
A Mechanistic Evaluation of the Nociceptive Desensitizing Properties of Topical Capsaicin
The aim of this project is to study the role of transient receptor potential (TRP-) channel V1 (TRPV1+) fibers in the development of cutaneous inflammation induced by epidermal Ultraviolet-B damage.
- Conditions
- Capsaicin, Ultaviolet B Light Burn, Neuropathic Pain, Lidocaine
- Trial name
- NCT03587220
- Testing
- Capsaicin Topical, Ultraviolet-B (UVB) irradiation, Histamine 1%
- Where
- Denmark
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Pain, Burning, Pain, Crushing
A Study of the Safety and Effectiveness of JNJ-42160443 as add-on Treatment in Patients With Cancer-related Pain
The purpose of this study is to compare the safety and effectiveness of JNJ-42160443 with placebo in the treatment of chronic, moderate to severe cancer-related pain in terminally ill patients with a diagnosis of active cancer.
- Conditions
- Pain, Burning, Pain, Crushing, Pain, Migratory, Pain, Radiating
- Trial name
- NCT00929188
- Testing
- JNJ-42160443
- Where
- 40 sites in United States, France and 3 more
- Volunteers
- 100 people
- Sponsor
- Janssen Research & Development, LLC