Clinical trials: Burden
Malnutrition, Malnutrition, Child
Double Duty Interventions and Its Impact on Double Burden of Malnutrition in Children Under Five Years
Background: Double burden of malnutrition is an emerging public health problem among children under-five years due to the inevitable consequences of nutritional transition.
- Conditions
- Malnutrition, Malnutrition, Child, Obesity, Undernutrition
- Trial name
- DBM (NCT05791305)
- Testing
- double duty intervention packages
- Where
- 2 sites in Ethiopia
- Volunteers
- 456 people
- Sponsor
- Debre Berhan University
Anxiety, Chemotherapy-induced Nausea and Vomiting
Use of Aromatherapy to Reduce Symptom Burden
The purpose of this study is to evaluate the effect of inhaled aromatherapy on symptoms of nausea/vomiting and anxiety in patients who have received a stem cell transplant.
- Trial name
- NCT05251337
- Testing
- Essential oils
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Indiana University
Caregiver Stress, Autism Spectrum Disorder
Sustainable Mindfulness and Resilience Training (SMART)
Investigators are proposing a 6-week mindfulness and resilience training intervention tailored for caregivers of children with autism.
- Trial name
- SMART (NCT04243694)
- Testing
- Mindfulness training
- Where
- United States
- Sponsor
- University of California, San Francisco
Caregiver Burden
SOSteniamoci: An Internet-based Intervention to Support Informal Caregivers.
The purpose of this study is to evaluate efficacy of internet intervention for informal caregivers in Italy in reducing their care-giving burden.
- Trial name
- NCT05301257
- Testing
- Intervention group SOSteniamoci
- Where
- Italy
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Dementia, Paratonia
Safety and Effectiveness of Botulinum Toxin in Elderly Patients With Dementia and Muscle Stiffness
Aim of the study is to perform a pilot study to assess the impact of Botulinum toxin on muscle tone, and caregiver burden in individuals who are cognitively impaired and who are fully dependent.
- Trial name
- NCT02212119
- Testing
- Botulinum Toxin, Saline
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Assistive Technology Clinic, Canada
Caregiver, Education
The Psychobiological Effects of Laughter Yoga: An Intervention Study
This study was conducted to determine the effect of Laughter Yoga-Based Mental Health Enhancement Training, applied to mothers of children with special needs, on the burden of care, positive mental health, perceived stress, and…
- Trial name
- NCT07314463
- Testing
- Laughter Yoga-Based Mental Health Strengthening Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Chatbot, Anxiety
The Impact of Chatbot-Assisted Nursing Education on Perceived Burden of Care and Caregiver Stress
Caregivers play a key role in the provision of day-to-day care and the coordination of care services. Caregivers of stroke patients use dysfunctional coping strategies to cope with the stressors and burden of care they encounter…
- Conditions
- Chatbot, Anxiety, Depression, Stress
- Trial name
- NCT06544421
- Testing
- Assigned Interventions
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Heart Failure, Atrial Fibrillation
Rhythm Control - Catheter Ablation With or Without Anti-arrhythmic Drug Control of Maintaining Sinus Rhythm Versus Rate Control With Medical Therapy and/or Atrio-ventricular Junction Ablation and Pacemaker Treatment for Atrial Fibrillation
Atrial fibrillation and heart failure are two common heart conditions that are associated with an increase in death and suffering. When both of these two conditions occur in a patient the patient's prognosis is poor.
- Trial name
- RAFT-AF (NCT01420393)
- Testing
- Rhythm control, Rate Control
- Where
- 21 sites in Brazil, Canada and 2 more
- Volunteers
- 411 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Metabolic Syndrome, Triglycerides
Therapeutic Lifestyle Modifications to Reduce Burden of Chronic Disease
The investigators previously established that there was a high burden of disease among all categories of staff at the University of the West Indies, St.
- Conditions
- Metabolic Syndrome, Triglycerides, Blood Pressure, Diabetes
- Trial name
- NCT01277614
- Testing
- Therapeutic lifestyle
- Where
- Trinidad and Tobago
- Volunteers
- 144 people
- Sponsor
- The University of The West Indies
Caregiver Burden
Educational Intervention Among Informal Caregivers of Person With Dementia
The goal of this intervention study is to test whether the educational intervention work well or not on informal caregiver of person with dementia.
- Trial name
- NCT06003647
- Testing
- Educational Intervention
- Volunteers
- 174 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Hemophilia
A Proof-of-concept Study to Reduce Treatment Burden in Haemophilia Participants Receiving Factor VIII and Factor IX Infusions
The main aim is to describe how the treatment burden and challenges of participants, relatives, and doctors during regular Factor VIII and Factor IX infusions to treat hemophilia evolve using a virtual-reality (VR) based…
- Trial name
- NCT05437211
- Testing
- Virtual-reality (VR) Based Solution
- Where
- 6 sites in France
- Volunteers
- 24 people
- Sponsor
- Takeda
Dementia, Caregiver Burden of People With Dementia
VR-based Mindfulness for Dementia Caregivers in the Home Environment (Mind-body Interventions)
To explore the feasibility, acceptability, and potential effectiveness among dementia caregivers of the mindfulness-based interventions delivered by VR technology (VR-based MBI) in improving psychological well-being and…
- Trial name
- vrmdc (NCT07103434)
- Testing
- VR Mindfulness intervention, Audio-based MBI, Waitlist control
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Caregiver Burnout
Feasibility of an Automated Bidet Intervention to Decrease Caregiver Burden
This study evaluates the feasibility, including acceptability and preliminary efficacy, of an automated bidet intervention to make it easier for caregivers to assist with toileting.
- Trial name
- NCT04283123
- Testing
- Automated Bidet, No Intervention
- Volunteers
- 10 people
- Sponsor
- Washington University School of Medicine
Colorectal Cancer
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE)
This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75.
- Trial name
- SCORE (NCT04406714)
- Testing
- Trial Mailed FIT Intervention - Age Group 50-75, Sub-Study Mailed FIT Intervention Enhanced Envelope - Age Group 45-49, Sub-Study Mailed FIT Active Comparator Plain Envelope - Age Group 45-49
- Where
- 2 sites in United States
- Volunteers
- 4,318 people, healthy volunteers welcome
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Atrial Fibrillation
A Study to Predict Atrial Fibrillation (AF) Burden in Participants With PAF and PsAF Treated With the VARIPULSE™ PFA Catheter
The purpose of this study is to evaluate how safe VARIPULSE™ Catheter is and how well it works in the treatment of participants with symptomatic paroxysmal atrial fibrillation (PAF; irregular heartbeat where episodes start and…
- Trial name
- SPECTRA-AF (NCT07788989)
- Testing
- VARIPULSE Catheter System (PVI), VARIPULSE Catheter System (PVI and PWI)
- Where
- United States
- Volunteers
- 2,300 people
- Sponsor
- Biosense Webster, Inc.
Indolent B-cell Non-Hodgkin's Lymphoma
GP2013 in Japanese Patients With CD20 Positive Low Tumor Burden Indolent B-cell Non-Hodgkin's Lymphoma
The purpose of this study is to evaluate safety and pharmacokinetic of GP2013 in Japanese patients with CD20 positive low tumor burden indolent B-cell NHL under weekly dosing schedule.
- Trial name
- NCT01933516
- Testing
- GP2013
- Where
- Japan
- Volunteers
- 6 people
- Sponsor
- Sandoz
Ischemic Heart Disease, Coronary Artery Disease
ITA Vs LAD; Evaluation of Inflammatory Burden in OP-CABG Patients
Introduction. Ischemic cardiomyopathy is one of the death leading causes in industrialized countries. Up-to-date ESC guidelines recommend a surgical approach (coronary by pass graft) in patients with multivessel coronaropathy…
- Conditions
- Ischemic Heart Disease, Coronary Artery Disease, Atherosclerosis, Inflammation
- Trial name
- NCT05574621
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- Cardiochirurgia E.H.
Caregiver Burden, Bereavement
Caregiver Stress and Bereavement
The death of a spouse is considered one of the most stressful and impactful life events and is associated with increased morbidity and premature mortality.
- Conditions
- Caregiver Burden, Bereavement, Cancer
- Trial name
- NCT05867706
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Early Life Adversity, Caregiver Stress
The Resilience Clinic Evaluation
Early life adversity can affect children's physical and mental health. The Resilience Clinic is a support program for young children and their caregivers who have been exposed to significant adversity, aiming to prevent the…
- Trial name
- NCT05690256
- Testing
- Resilience Clinic, Enhanced primary care
- Where
- 4 sites in United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Atrial Tachycardia
PVC Response ''Atrial Pace'' Inducing Atrial Tachycardias
Premature ventricular contractions (PVC) are common phenomenon and occasionally retrograde conduction from ventricle to atrium occurs and may cause pacemaker mediated tachycardia.
- Trial name
- NCT05344456
- Testing
- Change in the device PVC algorithm to ''Off''
- Where
- Finland
- Volunteers
- 16 people
- Sponsor
- Helsinki University Central Hospital