Clinical trials: Bronchoscopy, open to volunteers
Respiratory Disease
Procedural Skills Transfer in Bronchoscopy
Brief summary The goal of this Feasibility study is to capture bronchoscopy data from patients (Group1) and bronchoscopists (Group 2) over a period of three years.
- Trial name
- NCT07168408
- Where
- United Kingdom
- Volunteers
- 320 people
- Sponsor
- University of Edinburgh
Thoracic Surgery With One-lung Ventilation
Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement
One-lung ventilation is frequently required in thoracic surgery and is most commonly achieved using double-lumen endobronchial tubes (DLTs).
- Trial name
- NCT07465510
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Acute Respiratory Failure, Pneumonia
Practice of Oxygenation and Respiratory Support During Fiberoptic Bronchoscopy
The current practice of oxygenation and/or ventilation supports in patients undergoing Fiberoptic Bronchoscopy is very heterogeneous among studies published in the literature; in addition, clear outcomes advantages of one…
- Conditions
- Acute Respiratory Failure, Pneumonia, Lung Cancer, Fibrosis Lung
- Trial name
- NCT05681962
- Testing
- Bronchoscopy
- Where
- Italy
- Volunteers
- 10,000 people
- Sponsor
- University Magna Graecia
Small Pulmonary Nodules, Pulmonary Nodule Localization
Monarch Robotic Bronchoscopy for Lung Nodule ICG Dye Marking Before VATS
This is a single-center, prospective, single-arm clinical study conducted at Beijing Cancer Hospital to evaluate the effectiveness, safety, and learning curve of preoperative indocyanine green (ICG) dye marking mixed with…
- Conditions
- Small Pulmonary Nodules, Pulmonary Nodule Localization, Lung Cancer (Suspected or Confirmed), Video-assisted Thoracoscopic Surgery (VATS)
- Trial name
- REALM (NCT07177924)
- Testing
- Monarch RAB with CBCT-guided ICG Dye Marking
- Volunteers
- 50 people
- Sponsor
- Peking University Cancer Hospital & Institute
Aspiration Pneumonia, Bronchoscopy
FBS-ASaP: Fibrobronchoscopy in ASpiration Pneumonia in the Emergency Department
Non-Profit Prospective Observational Pilot Study The study will have an overall duration of 3 years, with patient enrollment starting after ethical committee approval.
- Trial name
- FBS-ASaP (NCT06511583)
- Testing
- Laryngotracheal Aspiration Procedure Using a Probe in the Emergency Department, Aspiration Procedure Using Fibrobronchoscopy in the Emergency Department
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Azienda Ospedaliero-Universitaria Careggi
Healthy Young Adults, Influenza Vaccines
Characterizing the Human Airway Immune Response to FluMist Vaccination
The goal of this clinical trial is to measure the immune response in the blood, nose, and lungs after participants receive either the FDA-approved inactivated influenza vaccine or the FDA-approved intranasal FluMist vaccine.
- Conditions
- Healthy Young Adults, Influenza Vaccines, Influenza Vaccine Response
- Trial name
- EVax-3 (NCT07177417)
- Testing
- FluMist, inactivated influenza vaccine, bronchoscopy
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
One Lung Ventilation in Thoracic Surgery
Comparison of Double-lumen Tube Intubation Between Fiberoptic Bronchoscopy and Video Laryngoscope
The goal of this clinical trial is to compare the first-attempt success rate in double-lumen tube intubation. The main question it aims to answer: Is there any difference in the first-attempt success rate of intubation between…
- Trial name
- NCT07241208
- Testing
- Fibertoptic Bronchoscopy
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Neoplasms, Airway Obstruction Upper
Difficult Airway Management in Oncology: An International Delphi Consensus Study (DAMO)
Airway management in patients with cancer carries risks that general difficult-airway guidelines do not address. Tumour in the head, neck, or mediastinum can distort or narrow the airway; previous radiotherapy causes fibrosis and…
- Conditions
- Neoplasms, Airway Obstruction Upper, Intubation, Intratracheal, Head and Neck Neoplasms
- Trial name
- DAMO (NCT07822815)
- Testing
- Questionnaire Administration
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Onco Critical Care Society
Lidocaine Spray, Nebulized Lidocaine
Comparison Between Different Ways for Using Lidocaine During FB
compare the efficacy and safety of nebulized lidocaine, oropharyngeal lidocaine spray, or their combination for better outcome of topical anesthesia in subjects undergoing diagnostic FB; severity of cough , pain during procedure…
- Conditions
- Lidocaine Spray, Nebulized Lidocaine, Lung Diseases, Lung Cancer
- Trial name
- NCT06563050
- Testing
- Nebulized lidocaine, Lidocaine spray, Combination of nebulized lidocaine and lidocaine spray
- Volunteers
- 240 people
- Sponsor
- Assiut University
Lung Cancer
EB-OCT Biopsy Guidance of Lung Cancer
Our objective is to develop, test, and validate a clinically robust polarization-sensitive optical coherence tomography (PS-OCT) biopsy guidance and diagnosis platform that is compatible with standard bronchoscopy techniques.
- Trial name
- NCT06556680
- Testing
- Optical coherence tomography
- Volunteers
- 200 people
- Sponsor
- Massachusetts General Hospital
Lung; Node
Robotic Systems Evaluation for Peripheral Pulmonary Lesions (RISE Trial)
This is an investigator-initiated cluster randomized control trial. The primary objective is to compare the diagnostic yield of two Food and Drug Administration (FDA) cleared national robotic assisted bronchoscopy platforms - the…
- Trial name
- NCT07735611
- Testing
- RAB via the Monarch platform, RAB via the ION platform
- Where
- United States
- Volunteers
- 398 people
- Sponsor
- Case Comprehensive Cancer Center
Lung Ground-Glass Opacity
GGO-dominant PPLs Diagnosis Using CLE and ssRAB-guided Cryobiopsy
The purpose of the study is to evaluate the diagnostic performance and safety of cryobiopsy for ground-glass opacity (GGO)-dominant peripheral pulmonary lesions (PPLs) under the guidance of shape-sensing robotic-assisted…
- Trial name
- NCT06910046
- Testing
- CLE and ssRAB-guided cryobiopsy
- Where
- China
- Volunteers
- 119 people
- Sponsor
- Shanghai Chest Hospital
Lung Cancer
Transbronchial MWA for Pulmonary Tumors
The purpose of the study is to evaluate the efficacy and safety of transbronchial microwave ablation for lung cancer.
- Trial name
- NCT06969014
- Testing
- Microwave ablation
- Where
- China
- Volunteers
- 15 people
- Sponsor
- Shanghai Chest Hospital
Hypoxemia, Pneumonia
Effect of High-Flow Nasal Cannula Oxygen Therapy on Hypoxemia in Pediatric Sedated Bronchoscopy
Due to children's lower oxygen reserves and higher oxygen consumption, sedation can easily lead to respiratory adverse events such as hypoxemia.
- Conditions
- Hypoxemia, Pneumonia, Pulmonary Neoplasm
- Trial name
- NCT07563075
- Testing
- High-flow nasal cannula, Regular Nasal Cannula
- Where
- 4 sites in China
- Volunteers
- 430 people
- Sponsor
- Zhejiang University
Supraglottic Airway Devices Position
Fiberoptic Bronchoscopy on Supraglottic Airway Devices Position
A comparison of SaCo VLMTM video laryngeal mask airway with the I-gel supraglottic airway during airway management in patients undergoing elective surgery.
- Trial name
- NCT06775184
- Testing
- a native video image system, Fiberoptic bronchoscope
- Volunteers
- 80 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Central Airway Obstruction
To Investigate Airway Oxygen Concentrations During Rigid Bronchoscopy Procedures Performed With High Frequency Jet Ventilation
Thermal ablation (use of treatment modalities that generate heat) has become a widely used tool for treatment of central airway obstruction (e.g. laser, electrocautery, radiofrequency, and argon plasma coagulation).
- Trial name
- NCT05881863
- Testing
- No intervention
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Minnesota
Foreign Body Aspiration
The Impact of Preoperative Nasal Capnography on Clinical Management in Patients Undergoing Diagnostic Bronchoscopy for Suspected Foreign Body Aspiration
Introduction Despite advances in medical care, foreign body aspiration remains a common and ongoing health concern in children. Diagnostic bronchoscopy is the gold standard for confirming the diagnosis and providing definitive…
- Trial name
- Capnography (NCT07870005)
- Testing
- Nasal capnographic examination
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Mersin University
Mediastinal Lymphadenopathy, Lung Cancer
Mediastinal EBUS Cryobiopsy Study In Sweden
This study is a prospective observational non-randomized clinical trial where all the participitants undergo the same procedure and every participitant's samples are compared to each other.
- Conditions
- Mediastinal Lymphadenopathy, Lung Cancer, Sarcoidosis, Lymphoma
- Trial name
- MECRIS (NCT06347939)
- Testing
- Mediastinal lymph nodes cryobiopsies
- Where
- 2 sites in Sweden
- Volunteers
- 200 people
- Sponsor
- Region Skane
Airway Management Assessment, Awake Endotracheal Intubation
Comparison of Awake Tracheal Intubation Methods
The aim of this study was to compare three different awake tracheal intubation technique -fiberoptic bronchoscopy (ATI:FB), videolaryngoscopy (ATI:VL), and fiberoptic bronchoscopy via a supraglottic airway device (ATI:SAD)- in…
- Conditions
- Airway Management Assessment, Awake Endotracheal Intubation, Awake Fiberoptic Nasal Intubation, Videolaryngoscopy
- Trial name
- ATI (NCT07484841)
- Testing
- Awake tracheal intubation viaFiberoptic Bronchoscopy (ATI:FOB), Awake tracheal Intubation via videolaryngoscopy (ATI:VL), awake tracheal intubation via aintree catheter loaded FOB through supraglottic airway device (ATI:SAD)
- Where
- Turkey (Türkiye)
- Volunteers
- 201 people
- Sponsor
- Kocaeli City Hospital
Lung Cancer (Diagnosis)
Robotic Bronchoscopy for Small Lung Nodules Without a Bronchus Sign
The goal of this observational study is to learn about the diagnostic performance and safety of robotic-assisted bronchoscopy using the Ion Endoluminal System in adults with small lung nodules that do not show a bronchus sign on…
- Trial name
- NCT07862816
- Where
- 4 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Intuitive Surgical