Clinical trials: Bronchoscopy
Airway Management, Education
The Training and Evaluate Effect on Clinical Airway Management for Novices.
In this self-control experiment, anesthesiologists without experiment of bronchoscopy working in anesthesiology department in Peking Union Medical College Hospital will receive a training and evaluation procedure in simulation…
- Conditions
- Airway Management, Education, Bronchoscopy
- Trial name
- NCT03856073
- Testing
- Novice
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Bronchoscopy, Sedation
Safety and Efficacy of Sufentanil Combined With Midazolam in Bronchoscopy Under Conscious Sedation: Retrospective Study
The aim of this study was to determine the safety and efficacy of sufentanil combined with midazolam in bronchoscopy under conscious sedation.
- Trial name
- NCT03890094
- Testing
- Sufentanil
- Where
- China
- Volunteers
- 11,158 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Lung Cancer Patients
Efficacy and Safety of Cryoablation with Robotic Bronchoscopy System in Patients with Lung Cancer
The goal of this single-arm clinical trial is to evaluate the safety and efficacy of robotic bronchoscopy system (RBS)-assisted cryoablation in the treatment of primary lung cancer in adult patients (aged ≥18 years) with…
- Trial name
- NCT06832956
- Testing
- robotic bronchoscopy system
- Volunteers
- 10 people
- Sponsor
- Guangzhou Medical University
Pneumonia, Resistant Pneumonia
Flexible Bronchoscopy in Resistant Pneumonia in PICU
Pneumonia remains a leading cause of morbidity and mortality among critically ill children admitted to Pediatric Intensive Care Units (PICUs).
- Conditions
- Pneumonia, Resistant Pneumonia, Resistant Pneumonia in Critically Ill Pedaitric Patients
- Trial name
- FFP-RP PICU (NCT07421440)
- Testing
- Flexible fiberoptic bronchoscopy with bronchoalveolar lavage (BAL)
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Mansour Gomaa Mohammed Saleh
Bronchoscopy
This Study Will Evaluate the Effectiveness of a Simple Intervention Through a Classical Yankauer Oral Suction Tube, in Decreasing the Sedative Medication Doses Needed to Provide Effective Patient Sedation During Bronchoscopy, Along With Its Effect on Both Patient's and Bronchoscopist Satisfaction
The aim of this study is to evaluate the effectiveness of a simple intervention through a classical Yankauer oral suction tube, a device known to have a proven safety profile in multiple healthcare settings, in decreasing the…
- Trial name
- NCT06908109
- Testing
- Yankauer Suction Device, Bronchoscopy
- Volunteers
- 120 people
- Sponsor
- American University of Beirut Medical Center
Bronchiectasis With Acute Exacerbation
Bronchoscopic Levofloxacin, Gentamicin, or Sham for Acute Exacerbation of Bronchiectasis
Randomized single-center trial evaluating whether bronchoscopic instillation of levofloxacin or gentamicin improves outcomes compared to a sham bronchoscopic procedure in adult ICU patients with non-cystic fibrosis bronchiectasis…
- Trial name
- NCT06209047
- Testing
- Local instillation of gentamicin and Budesonide, Local instillation of Levofloxacin and Budesonide, Bronchoscopic mechanical secretion suction and lavage
- Where
- Egypt
- Volunteers
- 315 people
- Sponsor
- Assiut University
Asthma, Mucus; Plug, Tracheobronchial
Study of Focal Airway Disease in Asthma Using Image Guided Bronchoscopy
This is a single center study of 60 subjects including those with asthma and mucus plugging, those with asthma and without mucus plugging, and healthy controls.
- Trial name
- SOFA (NCT04514913)
- Testing
- Multidetector Computed Tomography (MDCT) Scan, Virtual Navigation Bronchoscopy (VNB)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Thoracic Surgery With One-lung Ventilation
Ultrasound vs. Auscultation and Fiberoptic Bronchoscopy for Double-Lumen Tube Placement
One-lung ventilation is frequently required in thoracic surgery and is most commonly achieved using double-lumen endobronchial tubes (DLTs).
- Trial name
- NCT07465510
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Izmir City Hospital
Lung Cancer (Diagnosis), Lung Nodule
A Randomized Controlled Trial Comparing Percutaneous CT-Guided Biopsy and Shape-Sensing Robotic-Assisted Bronchoscopy
The ENCOMPASS study is a post-market, multicenter, randomized controlled trial comparing two established approaches for obtaining a biopsy of small pulmonary nodules (≤2 cm): CT-guided percutaneous lung nodule biopsy and…
- Trial name
- ENCOMPASS (NCT07761351)
- Testing
- Shape-Sensing Robotic-Assisted Bronchoscopy with Cone-Beam CT (ssRAB with CBCT), CT-guided percutaneous lung nodule biopsy
- Where
- 3 sites in Germany, Switzerland and 1 more
- Volunteers
- 550 people
- Sponsor
- Intuitive Surgical
Asthma
Depemokimab Asthma Imaging and Bronchoscopy Sub-Study
Asthma is a chronic condition marked by narrowed and swollen airways due to inflammation leading to recurring symptoms that can vary and worsen unpredictably.\xa0The purpose of this study is to assess how depemokimab, a…
- Trial name
- NCT06979323
- Testing
- Depemokimab
- Where
- 50 sites in United States, Belgium and 10 more
- Volunteers
- 150 people
- Sponsor
- GlaxoSmithKline
COPD
Bronchoscopic EmphysemA Treatment in THE NetherLands
Rationale: New bronchoscopic treatments for emphysema have shown promise in clinical trials, improving lung function, exercise capacity and possibly survival and are now being adopted by a number of centres in the Netherlands.
- Trial name
- BREATHE-NL (NCT02815683)
- Where
- 2 sites in Netherlands
- Volunteers
- 500 people
- Sponsor
- University Medical Center Groningen
Invasive Pulmonary Aspergillosis
Diagnosis of Invasive Pulmonary Aspergillosis, Specific Testing in Bronchial Secretions Versus Bronchoalveolar Fluid
The aim of this research project is to compare the results of Aspergillus specific test methods Aspergillus Galactomannan Enzyme Immunoassay (GM-EIA), Aspergillus polymerase chain reaction (PCR), Aspergillus Galactomannan Lateral…
- Trial name
- DipA2 (NCT04848831)
- Volunteers
- 100 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Lung Diseases, Desaturation of Blood
Finding the Optimal Location for Saturation Measurement During Flexible Bronchoscopy
An observational comparison of different locations of saturation measurements during Flexible Bronchoscopy
- Trial name
- NCT03062137
- Testing
- blood gas sampling
- Where
- Israel
- Volunteers
- 116 people
- Sponsor
- Rabin Medical Center
Pulmonary Disease, Chronic Obstructive, Pneumonia, Bacterial
Modulation of Steroid Immunosuppression by Alveolar Efferocytosis
The long-term goals of this study are (a) to understand the biological underpinnings for the increased incidence of community-acquired pneumonia in patients with chronic obstructive pulmonary disease (COPD) who are treated with…
- Trial name
- NCT03034642
- Testing
- Bronchoscopy with bilateral bronchoalveolar lavages
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Ann Arbor Healthcare System
Foreign Bodies, Tumor
The Effects of High-flow Nasal Oxygen on Oxygenation During Rigid Bronchoscopy Under General Anesthesia in Pediatric Patients
The aim of this study is to evaluate the effect of high-flow nasal cannula oxygen administration on maintenance of oxygenation and removal of carbon dioxide during apnoeic period in pediatric patients undergoing general…
- Conditions
- Foreign Bodies, Tumor, Stenosis of Trachea, Bronchus
- Trial name
- NCT03905733
- Testing
- Optiflow
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yonsei University
Peripheral Pulmonary Lesions
Clinical Utility of Needle-Based Confocal Laser Endomicroscopy for Peripheral Pulmonary Lesions
This prospective, multicenter diagnostic accuracy study will evaluate the clinical utility of needle-based confocal laser endomicroscopy (nCLE) for differentiating malignant from benign peripheral pulmonary lesions (PPLs).
- Trial name
- NCT07827326
- Testing
- Confocal Laser Endomicroscopy
- Where
- 3 sites in China
- Volunteers
- 100 people
- Sponsor
- First Affiliated Hospital of Ningbo University
Bronchopulmonary Disease
Nebulized Lignocaine for Topical Airway Anesthesia During Flexible Bronchoscopy: A Randomized Controlled Trial
Flexible bronchoscopy is one of the most widely performed procedures for diagnosis of various bronchopulmonary diseases. Most patients tolerate the procedure well although cough is often reported as a distressing symptom.
- Trial name
- NEBULA (NCT03040193)
- Testing
- Lignocaine Nebulization, Saline Nebulization
- Where
- India
- Volunteers
- 200 people
- Sponsor
- All India Institute of Medical Sciences
Stroke, Ischemic
MUcociliary Clearance IN Stroke
Stroke patients frequently suffer from stroke associated pneumonia. Pathophysiologically speaking, dysphagia and central nervous system (CNS)-injury induced immunosuppression largely contribute to the risk for pneumonia.
- Trial name
- MUCINS (NCT03884166)
- Testing
- bronchoscopy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Charite University, Berlin, Germany
Lung Cancer
Prospective Cohort of Diagnostic Bronchoscopy for Peripheral Lung Lesions
The primary objective is To evaluate the usefulness and safety of advanced guided bronchoscopy for histological diagnosis of peripheral pulmonary lesions.
- Trial name
- NCT05804786
- Testing
- Guided bronchoscopy
- Where
- 11 sites in South Korea
- Volunteers
- 1,240 people
- Sponsor
- Seoul National University Bundang Hospital
Tracheostomy Complications
Comparison Between Bronchoscopy and Real- Time Ultrasound Guided Percutaneous Tracheostomy
Trial is a randomized study to compare between ultrasound guided percutaneous tracheostomy and bronchoscopy guided percutaneous tracheostomy.
- Trial name
- NCT02656719
- Testing
- Ultrasound guided percutaneous tracheostomy, Bronchoscopy guided percutaneous tracheostomy
- Volunteers
- 80 people
- Sponsor
- Aykut Saritas