Clinical trials: Bronchoscopy
Adenopathy; Localized, Lung Cancer
Prospective Study to Evaluate Mapleson Circuit With Monitored Anesthesia Care During Endobronchial Ultrasound (EBUS) Bronchoscopy
If the investigators can prove that the use of a mapleson circuit attached to a nasal trumpet employed during monitored anesthesia care leads to less sedation requirements, less procedure interruptions, shorter procedure…
- Trial name
- NCT03815097
- Testing
- Mapleson circuit and nasal trumpet
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Multiple Primary Lung Cancer
ENB Guided MWA Combined With VATS Versus Sequential Surgery for Synchronous Bilateral Multiple Primary Lung Nodules
The goal of this clinical trial is to evaluate the safety and efficacy of ENB guided MWA combined with VATS versus sequential surgery for synchronous bilateral multiple primary lung nodules.
- Trial name
- NCT05662553
- Testing
- ENB guided MWA combined with VATS, sequential surgery
- Where
- China
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Bronchoscopy
Exploratory Study of Potential Pulmonary Aspiration Markers From Bronchoalveolar Lavage Fluid
The purpose of this study is to learn if chemicals from the mouth or stomach can be found in the lungs. This may suggest a process called aspiration.
- Trial name
- Pepsin (NCT00915941)
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Lung Neoplasms, Respiratory Failure
Clearance Of Mucus In Stents (COMIS)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
- Conditions
- Lung Neoplasms, Respiratory Failure, Pneumonia, Acute Coronary Syndromes
- Trial name
- NCT01370278
- Testing
- Normal Saline, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Pulmonary Nodules
The SEQUENCE Trial
This study will randomize participants undergoing a bronchoscopic biopsy of a peripheral pulmonary nodule for their standard of care to receive robotic-assisted bronchoscopy (RaB) and then staging linear endobronchial ultrasounnd…
- Trial name
- SEQUENCE (NCT06676956)
- Testing
- Linear EBUS first, Robotic-assisted bronchoscopy first
- Where
- 5 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Lung Disorder
Ventilatory Strategy for the Prevention of Atelectasis During Bronchoscopy Under General Anesthesia, VESPA Trial
This trial compares two different types of ventilation for the prevention of partial or complete collapsed lung (atelectasis) in patients undergoing bronchoscopy under general anesthesia.
- Trial name
- NCT04311723
- Testing
- Anesthesia Procedure, Bronchoscopy
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Rigid Bronchoscopy Ventilation
Clinical Effects of Different Ventilation Strategies in Rigid Bronchoscopy Procedures
This study compares the effects of different ventilation strategies on patient safety and respiratory parameters during rigid bronchoscopy procedures.
- Trial name
- RBV-HFJV (NCT07860918)
- Testing
- Jet Ventilation, Spontaneous Assisted Ventilation
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- The Affiliated Hospital of Qingdao University
Virtual Reality, Medical Education
Immersive Virtual Reality in Simulation-based Bronchoscopy Training
The purpose of this single-center randomized study is to investigate whether bronchoscopy training in an immersive Virtual Reality (iVR) environment will make the surgeon better at handling distractions and increase the quality…
- Trial name
- NCT05078762
- Testing
- Immersive Virtual Reality
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Sleep Apnea, Obstructive, Larynx
Accuracy of the Sensory Test Using the Laryngopharyngeal Endoscopic Esthesiometer in Obstructive Sleep Apnea
This is a prospective double blinded randomized crossover controlled trial aiming at validating the measurement of laryngopharyngeal mechanosensitivity in patients with suspected OSA using a recently developed laryngopharyngeal…
- Conditions
- Sleep Apnea, Obstructive, Larynx, Sensory Disorder
- Trial name
- NCT03109171
- Testing
- Laryngopharyngeal sensory test
- Where
- 2 sites in Colombia
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Fundación Neumologica Colombiana
Intubation, Endotracheal
3D Printed Model Simulator or Virtual Reality Software for Training Fiberoptic Intubation Skill
Fiberoptic-assisted intubation is an advanced skill that requires learners' practice as well as clinical experience during the anesthesiology residency training period.
- Trial name
- NCT05143606
- Testing
- 3D-printed airway simulator, virtual reality software, AirwayEx
- Where
- Thailand
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Bronchoscopy
Utility of Syringe Based Suction Versus Channel Suction in Bronchoalveolar Lavage
Bronchoalveolar lavage (BAL) is a common technique among pulmonologists. Its goal is to collect cells from alveolar units. This is done by wedging a flexible bronchoscope in a bronchus, instilling saline, and removing the saline…
- Trial name
- NCT01853904
- Testing
- Bronchoscopy/ BAL with Channel Suction, Bronchoscopy/BAL with Syringe Suction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Pulmonary Inflammation, Cytotoxicity
Pulmonary and Systemic Effects of Exposure to Wood Smoke
This is study is to assess pulmonary and systemic effects of exposure to wood smoke. Healthy volunteers will be expose under two different occasion to wood smoke and filtered air under two separated occasions with an interval of…
- Trial name
- NCT03302117
- Testing
- Wood smoke exposure
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Umeå University
Pulmonary Disease, Chronic Obstructive, Lung Diseases, Obstructive
Comparison of Alveolar Macrophages in Individuals With COPD Versus Smokers With Normal Pulmonary Function
The purpose of this study is to determine whether the alveolar macrophages (AMø) of patients with chronic obstructive pulmonary disease (COPD ) show abnormal responsiveness to bacterial and viral products, relative to smokers…
- Trial name
- NCT00281190
- Testing
- Blood drawing, Bronchoalveolar lavage during indicated bronchoscopy
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Asthma
Mechanistic Insights From Bronchoscopy Airway Samples
The purpose of this study is to examine the mechanisms of asthma. The investigators are comparing the cells of individuals with and without asthma and looking at the roles various parts of the cell play in the production and…
- Trial name
- MIBAS (NCT06105710)
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Respiratory Insufficiency
Evaluation of Leak-free Bronchoscope Adapter
Patients who develop respiratory failure require the assistance of mechanical ventilation while recovering from their respiratory injury.
- Trial name
- NCT05288218
- Testing
- Leak-free Bronchoscope Adapter, Standard Bronchoscope Adapter
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Fiberoptic Bronchoscopy
Determination of Fiberoptic Bronchoscopy Sedation Protocols in Turkey
Fiberoptic bronchoscopy (FOB), which is difficult to tolerate while awake, is recommended to be performed by the patient under sedation.
- Trial name
- NCT06000995
- Testing
- Survey Questions
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Samsun University
Tracheal Intubation in Children
Ambu Aura-i and Air-Q Intubating Laryngeal Airways as a Conduit for Tracheal Intubation in Children
The purpose of this study is to determine whether there is a clinically relevant difference in time to tracheal intubation when using fiberoptic bronchoscope as a guide to intubate through the Ambu Aura-i or air-Q ILA.
- Trial name
- NCT01535742
- Testing
- Ambu Aura-i size 1.5, air-Q ILA size 1.5, Ambu Aura-i size 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Influenza, SARS-CoV-2 (COVID-19) Infection
Dissecting Human Immune Responses to Infection With Influenza or SARS-CoV-2
The purpose of this study is to evaluate the virus-specific immune response in people who are symptomatic with confirmed influenza or COVID-19.
- Conditions
- Influenza, SARS-CoV-2 (COVID-19) Infection, Immune Response of Host
- Trial name
- WU 437 (NCT06848309)
- Testing
- Bronchoscopy
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Peripheral Pulmonary Nodules, Lung; Node
CBCT-Guided Navigational Bronchoscopy For Lung Nodules
The purpose of this study is to determine if the cone beam computed tomography (CBCT)-guided navigation bronchoscopy is better in diagnosing lung nodules compared to navigation bronchoscopy alone.
- Conditions
- Peripheral Pulmonary Nodules, Lung; Node, Cone Beam Computed Tomography, Guided Navigation Bronchoscopy
- Trial name
- NCT04758403
- Testing
- Navigation Bronchoscopy, Cone beam computed tomography (CBCT)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Bronchoscopy, Obstructive Sleep Apnea
Upper Airway Collapsibility Evaluation in Different Sedative Levels by Sleep Endoscopy
The purpose of this study is to evaluate the upper airway collapsibility by sleep endoscopy in different sedative levels. Propofol pump infusion will be used to achieve conscious sedation.
- Conditions
- Bronchoscopy, Obstructive Sleep Apnea, Conscious Sedation
- Trial name
- NCT01100554
- Testing
- Sleep endoscopy
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital