Clinical trials: Bronchoscopy
Anesthesia Intubation Complication
Video-stylet for Nasotracheal Intubation in Limited Mouth Opening Patient
The aim of the study is to investigate the efficiency of the Video-stylet (Trachway ®) and the fiberoptic bronchoscopy in facilitation of nasotracheal intubation in limited mouth opening patients.
- Trial name
- NCT01917435
- Testing
- video-stylet, fiberoptic bronchoscope
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Acute Lung Inflammation
Effects of Bronchial Segmental Endotoxin Instillation in Humans
Background: When bacteria enter the lungs, serious infections can occur. Researchers want to learn more about the process of inflammation in the lungs by studying lung cells and the products that they make.
- Trial name
- NCT02392442
- Testing
- Saline, Endotoxin
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Bronchoscopy, O2-supplementation
Toward the Development of a Bronchoscope With a Dedicated O2 Channel ?
Feasibility of using an extra bronchoscopic channel for supplementation of oxygen will be studied by comparing O2-supplementation by nasal cannulae versus O2-supplementation through aspiration channel of the bronchoscope.
- Trial name
- NCT01963377
- Testing
- O2 through nasal cannulae, O2-channel
- Where
- Belgium
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Saint Pierre
Leukocyte Disorders, Respiratory Tract Diseases
Collection of Lung Fluid and Tissue Samples for Research
This study will collect fluid and tissue specimens from the lungs and nose of healthy people and people with a history of lung infections.
- Conditions
- Leukocyte Disorders, Respiratory Tract Diseases, Bronchoscopy
- Trial name
- NCT00471250
- Where
- United States
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Airway Management, Education
The Training and Evaluate Effect on Clinical Airway Management for Novices.
In this self-control experiment, anesthesiologists without experiment of bronchoscopy working in anesthesiology department in Peking Union Medical College Hospital will receive a training and evaluation procedure in simulation…
- Conditions
- Airway Management, Education, Bronchoscopy
- Trial name
- NCT03856073
- Testing
- Novice
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Bronchoscopy, Sedation
Safety and Efficacy of Sufentanil Combined With Midazolam in Bronchoscopy Under Conscious Sedation: Retrospective Study
The aim of this study was to determine the safety and efficacy of sufentanil combined with midazolam in bronchoscopy under conscious sedation.
- Trial name
- NCT03890094
- Testing
- Sufentanil
- Where
- China
- Volunteers
- 11,158 people, healthy volunteers welcome
- Sponsor
- Guangzhou Institute of Respiratory Disease
Asthma, Mucus; Plug, Tracheobronchial
Study of Focal Airway Disease in Asthma Using Image Guided Bronchoscopy
This is a single center study of 60 subjects including those with asthma and mucus plugging, those with asthma and without mucus plugging, and healthy controls.
- Trial name
- SOFA (NCT04514913)
- Testing
- Multidetector Computed Tomography (MDCT) Scan, Virtual Navigation Bronchoscopy (VNB)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pulmonary Disease, Chronic Obstructive, Pneumonia, Bacterial
Modulation of Steroid Immunosuppression by Alveolar Efferocytosis
The long-term goals of this study are (a) to understand the biological underpinnings for the increased incidence of community-acquired pneumonia in patients with chronic obstructive pulmonary disease (COPD) who are treated with…
- Trial name
- NCT03034642
- Testing
- Bronchoscopy with bilateral bronchoalveolar lavages
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- VA Ann Arbor Healthcare System
Tracheostomy Complication, Tracheostomy Infection
The Ultrasound-guided vs Bronchoscopy-guided vs Ultrasound-bronchoscopy-guided Percutaneous Tracheostomy Trial
This trial (BRONCUS) is a randomized one designed to evaluate the overall safety of ultrasound guided compared to bronchoscopy guided compared to ultrasound-bronchoscopy guided percutaneous tracheostomy, in order to find out if…
- Conditions
- Tracheostomy Complication, Tracheostomy Infection, Tracheostomy Hemorrhage
- Trial name
- BRONCUS-PDT (NCT06226142)
- Testing
- Percutaneous dilatational tracheostomy
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Atopic Asthma, Healthy
Genetics of Asthma - Bronchoscopy Studies
The purpose of this study is to identify the mediators and genes in airway epithelial and BAL cells that are differentially regulated following inhalation of endotoxin lipopolysaccharide (LPS) among study participants with…
- Trial name
- NCT00644514
- Testing
- Endotoxin - lipopolysaccharide (LPS)
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- John Sundy
Adverse Effects
Optimal TCI Regimen for Sedation of Elderly Undergoing Fiberoptic Bronchoscopy
Target-Controlled Infusion (TCI) of Propofol has been proved to be a safe agent for conscious sedation in flexible bronchoscopy (FB) .However, the target setting of "effect-site" concentration (Cet) of propofol is still unclear…
- Trial name
- NCT02927587
- Testing
- The induction Cet of propofol
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- The Second Affiliated Hospital of Dalian Medical University
Intubating Conditions, Postoperative Myalgia
Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application aof rocuronium, reversed by sugammadex.
- Conditions
- Intubating Conditions, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01996358
- Testing
- Succinylcholine, Rocuronium 0,3, Rocuronium 0,6
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Supplementary Vitamins on Oxidant Gene Expression in the Lungs of Healthy Smokers
Smoking damages the airway epithelium. The major mechanism by which this is done is by molecules called free radicals. Our body attempts to deal with these damaging molecules in two ways.
- Trial name
- NCT00565214
- Testing
- Group 1, Group 2
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Bronchoscopy
Utility of Syringe Based Suction Versus Channel Suction in Bronchoalveolar Lavage
Bronchoalveolar lavage (BAL) is a common technique among pulmonologists. Its goal is to collect cells from alveolar units. This is done by wedging a flexible bronchoscope in a bronchus, instilling saline, and removing the saline…
- Trial name
- NCT01853904
- Testing
- Bronchoscopy/ BAL with Channel Suction, Bronchoscopy/BAL with Syringe Suction
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Anesthesia, Bronchoscopy
Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy
The goal of this clinical trial is to evaluate whether mivacurium chloride and succinylcholine can provide effective and safe muscle relaxation in adult patients aged 18-60 years undergoing bronchoscopy who require muscle…
- Conditions
- Anesthesia, Bronchoscopy, Muscle Relaxants
- Trial name
- NCT06709066
- Testing
- mivacurium chloride, succinylcholine
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Peng Liang
Tracheal Intubation in Children
Ambu Aura-i and Air-Q Intubating Laryngeal Airways as a Conduit for Tracheal Intubation in Children
The purpose of this study is to determine whether there is a clinically relevant difference in time to tracheal intubation when using fiberoptic bronchoscope as a guide to intubate through the Ambu Aura-i or air-Q ILA.
- Trial name
- NCT01535742
- Testing
- Ambu Aura-i size 1.5, air-Q ILA size 1.5, Ambu Aura-i size 2
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Satisfaction, Personal
3D Printing in Airway Anatomy and Bronchoscopy Education
The main purpose of this study is to use 3D printing technology to make a human anatomical bronchial tree model, which is applied in medical education for medical students and students of the department of respiratory therapy.
- Trial name
- NCT05410236
- Testing
- 3D bronchial tree model
- Where
- Taiwan
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Fu Jen Catholic University
Flexible Bronchoscopy, Simulation Training
Learning-curve-based Simulation Training for Bronchoscopic Intubation
This study aims to determine whether a new learning-curve-based simulation training modality could contribute to a noninferiority regarding bronchoscopic-guided intubation time in patients compared with the reference…
- Conditions
- Flexible Bronchoscopy, Simulation Training, Intubation Time
- Trial name
- NCT05383729
- Testing
- learning-curve-based training modality, fixed-training-time training modality
- Where
- 2 sites in China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Virtual Reality, Medical Education
Immersive Virtual Reality in Simulation-based Bronchoscopy Training
The purpose of this single-center randomized study is to investigate whether bronchoscopy training in an immersive Virtual Reality (iVR) environment will make the surgeon better at handling distractions and increase the quality…
- Trial name
- NCT05078762
- Testing
- Immersive Virtual Reality
- Where
- Denmark
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Tomography, Optical Coherence, Bronchoscopy
Measure Airway Compliance by Endobronchial Optical Coherence Tomography
Optical Coherence Tomography （OCT）is a novel, non-invasive, high resolution special optical imaging techniques. In airway, Measure airway area and airway wall thickness is the most usage of Endobronchial Optical Coherence…
- Conditions
- Tomography, Optical Coherence, Bronchoscopy, Respiratory Disease, Airway Remodeling
- Trial name
- NCT05692362
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University