Clinical trials: Bronchoscopy
General Anesthesia and Bronchoscopy Sedation
A Non-intervention Fiberoptic Bronchoscopy Study of Remazolam Toluene Sulfonate for Injection Under General Anesthesia and Fiberoptic Bronchoscopy
This is a non-interventional study of remazolam toluenesulfonate (rebenin ®) for injection in Chinese patients. A total of 1000 patients were enrolled in this study based on the preliminary safety assessment of rebenin ®, and all…
- Trial name
- NCT05549791
- Testing
- Remimazolam Tosilate for Injection
- Where
- China
- Volunteers
- 1,285 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Lung Cancer
Airway Epithelium Gene Expression: AEGIS IDE
The purpose of the research study is to develop a new, more sensitive, and less invasive test for diagnosing lung cancer at an earlier stage, when it can more easily be cured.
- Trial name
- AEGIS IDE (NCT00746759)
- Testing
- Biomarker (not used as an intervention)
- Where
- 21 sites in United States
- Volunteers
- 1,331 people
- Sponsor
- Allegro Diagnostics, Corp.
Sedation or Anesthesia
A Trial Evaluating the Efficacy and Safety of HSK3486 Injectable Emulsion in Subjects Undergoing Fiberoptic Bronchoscopy
This is a Multi-Center, Randomized, Double-Blind, Propofol-Controlled Phase III Clinical Trial. Around 260 eligible subjects are planned to be enrolled and randomized in a 1:1 ratio to either the HSK3486 arm or propofol arm.
- Trial name
- NCT04111159
- Testing
- HSK3486, Propofol
- Where
- China
- Volunteers
- 267 people
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
Peripheral Lung Tumor
Padeliporfin VTP Using Robotic Assisted Bronchoscopy in Peripheral Lung Cancer
Phase 1/1b, safety, feasibility, and light dose titration study followed by further study of therapeutic ablation effects. Patients with high risk of peripheral primary lung cancer, stage 1A1/1A2, for whom surgical treatment is…
- Trial name
- NCT05918783
- Testing
- Padeliporfin Vascular Targeted Photodynamic (VTP) therapy
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Impact Biotech Ltd
Nsclc
A Trial of PTS Via Intratumoral Injection in Patients With Central Air Way NSCLC Severe Obstruction
This trial was to evaluate the efficacy of intratumoral PTS injection in alleviating airway obstruction and dyspnea by improving the percentage of lumen patency of patients with central air way NSCLC tumor severe obstruction.
- Trial name
- NCT03448146
- Testing
- Para-Toluenesulfonamide
- Where
- China
- Volunteers
- 90 people
- Sponsor
- PTS International Inc.
Flexible Bronchoscopy
A Study of AQUAVAN® Injection for Sedation in Elderly Patients Undergoing Flexible Bronchoscopy
This study was designed to demonstrate that AQUAVAN® is effective in providing adequate sedation in patients undergoing flexible bronchoscopy as well as to assess the safety profile of AQUAVAN versus that of midazolam.
- Trial name
- NCT00209586
- Testing
- fospropofol disodium
- Volunteers
- 55 people
- Sponsor
- Eisai Inc.
Lung Lesion(s) Requiring Evaluation
Transbronchial Lung Biopsy Guided by ENB
The purpose of this study is to evaluate the performance and safety of electromagnetic navigation bronchoscopy (ENB) system and system kit (iLungTM SuperNavigator) .
- Trial name
- NCT03628222
- Testing
- ENB-TBLB, X-ray-TBLB
- Where
- 8 sites in China
- Volunteers
- 226 people
- Sponsor
- Changzhou LungHealth Medtech Company Limited
Atelectasis, Bronchoscopy
Evaluation of BAL Procedure With Ambu aScope 3 Large in Patients in an ICU Setting
An Investigation to determine the single-use scope's ability to suction secretion from the lungs to resolve the collapse of the lung.
- Trial name
- NCT03581474
- Testing
- Bronchoscopic procedure
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Ambu A/S
Asthma
Assessment Of Disease Pathology And Key Therapeutic Targets In Severe Asthma
To evaluate and compare the expression and change in expression of key severe asthma targets at baseline in mile to moderate asthmatics vs. severe asthmatic subjects.
- Trial name
- NCT00327197
- Testing
- Prednisolone, Bronchoscopy
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- GlaxoSmithKline
Pulmonary Emphysema
US 10 mL Bronchoscopic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study - Initial Formulation
The purpose of this study is to determine whether the Aeris Bronchoscopic Lung Volume Reduction (BLVR) System is safe in patients with advanced emphysema.
- Trial name
- NCT00085852
- Testing
- BLVR
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Aeris Therapeutics
Pulmonary Emphysema
US 10 mL Biologic Lung Volume Reduction (BLVR) Phase 1 Emphysema Study
The purpose of this study is to evaluate the safety of the Biologic Lung Volume Reduction System (BLVR) for patients with advanced emphysema.
- Trial name
- NCT00347659
- Testing
- BLVR System
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Aeris Therapeutics
Lung Diseases, Lung Neoplasms
Observational Bronchoscopy Video Data Collection Study With Adult Patients
The primary aim is to develop a software algorithm that has the capacity to detect the normal 18 anatomical structures of the lung by using the position of the scope during the bronchoscopy procedure and using existing…
- Conditions
- Lung Diseases, Lung Neoplasms, Lung Cancer, Lung Transplantation
- Trial name
- NCT06465797
- Testing
- Bronchoscopy
- Where
- Denmark
- Volunteers
- 115 people
- Sponsor
- Ambu A/S
Lung Lesion(s) Requiring Evaluation
NAVIGATE: Clinical Evaluation of superDimension™ Navigation System for Electromagnetic Navigation Bronchoscopy™
The purpose of this study is to evaluate outcomes following electromagnetic navigation bronchoscopy™ (ENB™) procedures using the superDimension™ navigation system.
- Trial name
- NCT02410837
- Testing
- Electromagnetic Navigation Bronchoscopy
- Where
- 37 sites in United States, Austria and 5 more
- Volunteers
- 1,388 people
- Sponsor
- Medtronic - MITG
Lung Neoplasms
Confocal Laser Endomicroscopy Nodule Localization by Robotic Bronchoscopy
This study is designed to evaluate the safety and feasibility of real-time needle-based confocal laser endomicroscopy (nCLE) in improving diagnostic accuracy of robotic-assisted bronchoscopy (RANB) biopsy performed with the…
- Trial name
- CLEAR (NCT05231278)
- Testing
- nCLE aided RANB biospy
- Where
- 4 sites in United States
- Volunteers
- 53 people
- Sponsor
- Johnson & Johnson Enterprise Innovation Inc.
Cancer of the Lung, Lung Cancer
Circulating Tumor DNA in Patients at High Risk for Lung Cancer
Patients who are about to undergo a diagnostic or therapeutic bronchoscopy or thoracic surgery without a distant history of cancer will have their blood drawn for measurement of circulating tumor DNA (ctDNA) to validate the…
- Conditions
- Cancer of the Lung, Lung Cancer, Lung Neoplasms, Adenocarcinoma of the Lung
- Trial name
- NCT02715102
- Where
- United States
- Volunteers
- 39 people
- Sponsor
- Pathway Genomics
Bronchoscopy, Anesthesia
Prospective Non-interventional Evaluation of Intubation and Intensive Care Use of the New aScope™ 4 Broncho and aView
This study is designed as a prospective observational, non-controlled, non-interventional study. The aim of this study is to obtain a broad user perspective of the aScope™ 4 Broncho, focusing on the device functionalities within…
- Trial name
- NCT03294213
- Testing
- aScope 4 Broncho
- Where
- Germany
- Volunteers
- 176 people
- Sponsor
- Ambu A/S
Lung Neoplasms
POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)
This is a prospective, multicenter, single-arm study on transbronchial microwave ablation using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris…
- Trial name
- NCT05299606
- Testing
- Transbronchial Microwave Ablation
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 12 people
- Sponsor
- Ethicon, Inc.
Pulmonary Coin Lesion
Pilot Study to Measure Lung Biopsy Diagnostic Yield Using Always On Electromagnetic Tip Tracked Devices
The objective of the prospective, multi-center study is to evaluate the ease of use and effectiveness of the SPiN Drive Electromagnetic (EM) Tip Tracked Steerable Devices as a method of sampling subsegmental, less than 3.0 cm…
- Trial name
- ALOSPNDY (NCT01389154)
- Testing
- Lung biopsy using Always On EM Tip Tracked Device
- Sponsor
- Veran Medical Technologies
Asthma
A Study Evaluating the Effects of Lebrikizumab on Airway Eosinophilic Inflammation in Participants With Uncontrolled Asthma
This Phase II, randomized, double-blind, placebo-controlled, multicenter study will evaluate the effects of lebrikizumab on airway eosinophilic inflammation in participants with uncontrolled asthma who are using inhaled…
- Trial name
- NCT02099656
- Testing
- Lebrikizumab, Inhaled corticposteroids (ICS), Second Asthma Controller Medication
- Where
- 28 sites in United States, Canada and 4 more
- Volunteers
- 64 people
- Sponsor
- Hoffmann-La Roche
Tumor, Hemoptysis
Post Market Study to Collect Data for Software Recognizing the Anatomical Structures During Bronchoscopy.
The primary aim is to develop a software algorithm that has the capacity to detect the normal 18 anatomical structures of the lung by using the position of the scope during the bronchoscopy procedure and using existing…
- Conditions
- Tumor, Hemoptysis, Pulmonary Disease
- Trial name
- NCT04770675
- Testing
- Bronchoscopy
- Where
- Denmark
- Volunteers
- 833 people
- Sponsor
- Qmed Consulting A/S