Clinical trials: Bronchoscopy
Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes
Topical Application of Cocaine HCl 4% and 10% on Safety and Efficacy in Local (Topical) Anesthesia
This study aims to evaluate topical application of Cocaine HCl 4% and 10% on safety and efficacy in local (topical) anesthesia for diagnostic procedures and surgeries on or through accessible mucous membranes of the nasal…
- Conditions
- Diagnostic, Procedures and Surgeries on or Through Accessible Mucous Membranes, of the Nasal Cavities
- Trial name
- NCT01746940
- Testing
- Cocaine HCl 4% Topical Solution, Cocaine HCl 10% Topical Solution
- Where
- 2 sites in United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- Lannett Company, Inc.
Lung Neoplasms
POWER Study (Prospective Transbronchial Microwave + Robotic-Assisted Bronchoscopy)
This is a prospective, multicenter, single-arm study on transbronchial microwave ablation using the NEUWAVE FLEX Microwave Ablation System and Accessories on oligometastatic tumors in the peripheral lung, guided by the Auris…
- Trial name
- NCT05299606
- Testing
- Transbronchial Microwave Ablation
- Where
- 10 sites in United States, Canada and 1 more
- Volunteers
- 12 people
- Sponsor
- Ethicon, Inc.
Lung Neoplasms
A Study of Robot-Assisted Bronchoscopy in Chinese Participants With Lung Lesions
Robot-assisted bronchoscopy biopsy procedure will be conducted for all eligible subjects under general anesthesia status by trained investigators in hospital.
- Trial name
- NCT05426213
- Testing
- Robot-assisted Bronchoscopy (Monarch Platform)
- Sponsor
- Auris Health, Inc.
Lung Cancer (Diagnosis)
Robotic Bronchoscopy for Small Lung Nodules Without a Bronchus Sign
The goal of this observational study is to learn about the diagnostic performance and safety of robotic-assisted bronchoscopy using the Ion Endoluminal System in adults with small lung nodules that do not show a bronchus sign on…
- Trial name
- NCT07862816
- Where
- 4 sites in South Korea
- Volunteers
- 151 people
- Sponsor
- Intuitive Surgical
Asthma
Comparison Of Molecular Targets In Mild To Severe Asthmatics And Healthy Subjects
The primary goal of this study is to compare the expression of key GSK drug targets across the 4 asthma phenotypes and healthy subjects and secondarily to evaluate changes in target expression in response to a 2-week course of…
- Trial name
- NCT00331058
- Testing
- Bronchoscopsy, Prednisolone
- Where
- 2 sites in United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Lung Lesion(s) Requiring Evaluation
NAVIGATE: Clinical Evaluation of superDimension™ Navigation System for Electromagnetic Navigation Bronchoscopy™
The purpose of this study is to evaluate outcomes following electromagnetic navigation bronchoscopy™ (ENB™) procedures using the superDimension™ navigation system.
- Trial name
- NCT02410837
- Testing
- Electromagnetic Navigation Bronchoscopy
- Where
- 37 sites in United States, Austria and 5 more
- Volunteers
- 1,388 people
- Sponsor
- Medtronic - MITG
Lung Biopsy
A Multicenter Study in Bronchoscopy Combining Stimulated Raman Histology With Artificial Intelligence for Rapid Lung Cancer Detection - The ON-SITE Study
The ON-SITE study represents a prospective, observational study focused on the training/tuning and pivotal validation of deep learning algorithms that detect cell/tissue morphology suspicious for cancer in biopsies of peripheral…
- Trial name
- ON-SITE (NCT07045103)
- Where
- 7 sites in United States
- Volunteers
- 900 people
- Sponsor
- Invenio Imaging Inc.
General Anesthesia and Bronchoscopy Sedation
A Non-intervention Fiberoptic Bronchoscopy Study of Remazolam Toluene Sulfonate for Injection Under General Anesthesia and Fiberoptic Bronchoscopy
This is a non-interventional study of remazolam toluenesulfonate (rebenin ®) for injection in Chinese patients. A total of 1000 patients were enrolled in this study based on the preliminary safety assessment of rebenin ®, and all…
- Trial name
- NCT05549791
- Testing
- Remimazolam Tosilate for Injection
- Where
- China
- Volunteers
- 1,285 people, healthy volunteers welcome
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Lung Cancer
Assessment of Diagnostic Yield Using a Robotic Navigational Bronchoscopy System With CBCT
The aim of this research study is to evaluate the effectiveness of the ION endoluminal system at reaching and obtaining biopsies from lung nodules when used in combination with 3-dimensional imaging such as CT scans.
- Trial name
- NCT06084208
- Testing
- Biopsy with the Robotic- Ion Endoluminal System with Adjunct Real-time Imaging
- Where
- Netherlands
- Volunteers
- 132 people
- Sponsor
- Intuitive Surgical
Emphysema
A Randomized Controlled Trial of InterVapor® in France - The TARGET Trial
This study is designed to prospectively document changes in FEV1 and health-related quality of life 12 months following sequential segmental treatment with InterVapor® in patients with heterogeneous emphysema with upper lobe…
- Trial name
- NCT05118269
- Testing
- Treatment plus Optimal Medical Therapy, Optimal Medical Therapy
- Where
- France
- Volunteers
- 3 people
- Sponsor
- Uptake Medical Technology, Inc.
Lung Lesion(s) Requiring Evaluation
Transbronchial Lung Biopsy Guided by ENB
The purpose of this study is to evaluate the performance and safety of electromagnetic navigation bronchoscopy (ENB) system and system kit (iLungTM SuperNavigator) .
- Trial name
- NCT03628222
- Testing
- ENB-TBLB, X-ray-TBLB
- Where
- 8 sites in China
- Volunteers
- 226 people
- Sponsor
- Changzhou LungHealth Medtech Company Limited
Sedation
A Clinical Study of Remimazolam Tosilate in Patients Undergoing Bronchoscopy
A multicenter, randomized, single-blind, active controlled, parallel group study comparing remimazolam tosilate to propofol in patients undergoing bronchoscopy.
- Trial name
- NCT04400201
- Testing
- Remimazolam Tosilate, Propofol
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Tumor, Hemoptysis
Post Market Study to Collect Data for Software Recognizing the Anatomical Structures During Bronchoscopy.
The primary aim is to develop a software algorithm that has the capacity to detect the normal 18 anatomical structures of the lung by using the position of the scope during the bronchoscopy procedure and using existing…
- Conditions
- Tumor, Hemoptysis, Pulmonary Disease
- Trial name
- NCT04770675
- Testing
- Bronchoscopy
- Where
- Denmark
- Volunteers
- 833 people
- Sponsor
- Qmed Consulting A/S
Lung Cancer
Auris Robotic Endoscopy System for Bronchoscopy
In this study, the performance related to the use of the novel Robotic Endoscopy Platform during bronchoscopic procedures will be evaluated.
- Trial name
- NCT03497026
- Testing
- Robotic Bronchoscopy Platform
- Where
- 2 sites in United States
- Volunteers
- 4 people
- Sponsor
- Auris Health, Inc.
Asthma
Assessment Of Disease Pathology And Key Therapeutic Targets In Severe Asthma
To evaluate and compare the expression and change in expression of key severe asthma targets at baseline in mile to moderate asthmatics vs. severe asthmatic subjects.
- Trial name
- NCT00327197
- Testing
- Prednisolone, Bronchoscopy
- Where
- United Kingdom
- Volunteers
- 47 people
- Sponsor
- GlaxoSmithKline
Lung; Node
Robotic Bronchoscopy for Peripheral Pulmonary Lesions
In this study, the feasibility of performing robotic navigation of peripheral airways in human subjects for the purpose of biopsying peripheral lung lesions will be evaluated.
- Trial name
- NCT03727425
- Testing
- Robotic assisted bronchoscopy
- Where
- 5 sites in United States
- Volunteers
- 55 people
- Sponsor
- Auris Health, Inc.
Lung Cancer, Lung Diseases
Adequacy Assessment of Bronchoscopic Biopsy Samples Using a Novel Instrument
The goal of this study is to learn whether the Ruby Robotics system enables pathologists to determine whether a bronchoscopic biopsy sample is adequate for diagnosis.
- Trial name
- NCT06499454
- Testing
- Ruby ROSE evaluation
- Volunteers
- 50 people
- Sponsor
- Ruby Robotics Inc
Asthma
A Study Evaluating the Effects of Lebrikizumab on Airway Eosinophilic Inflammation in Participants With Uncontrolled Asthma
This Phase II, randomized, double-blind, placebo-controlled, multicenter study will evaluate the effects of lebrikizumab on airway eosinophilic inflammation in participants with uncontrolled asthma who are using inhaled…
- Trial name
- NCT02099656
- Testing
- Lebrikizumab, Inhaled corticposteroids (ICS), Second Asthma Controller Medication
- Where
- 28 sites in United States, Canada and 4 more
- Volunteers
- 64 people
- Sponsor
- Hoffmann-La Roche
Asthma
A Methodology Study To Look At Genes In Lung Cells And Tissue From Asthmatic Patients
The primary goal of this study is to identify a gene or panel of genes which are differentially expressed in lung cells and tissue from asthmatic patients following administration of Ipratropium bromide and eiTher nebulised…
- Trial name
- NCT00331292
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- GlaxoSmithKline
Intubating Conditions, Postoperative Myalgia
Comparing Intubating Conditions Using Succinylcholine or Rocuronium for Rigid Bronchoscopy
Succinylcholine is commonly used for neuromuscular relaxation for short procedures such as rigid bronchoscopy. A more modern alternative is the application aof rocuronium, reversed by sugammadex.
- Conditions
- Intubating Conditions, Postoperative Myalgia, Patient Satisfaction
- Trial name
- NCT01996358
- Testing
- Succinylcholine, Rocuronium 0,3, Rocuronium 0,6
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Dr. Horst Schmidt Klinik GmbH