Clinical trials: Bronchitis
Splenomegaly; Congestive, Chronic, Panhematopenia; Splenic
Ultrasound Guided Microwave Ablation of Splenomegaly in Children
Children with liver cirrhosis frequently develops portal hypertension. One of the serious complications to portal hypertension is splenomegaly, which may result in pancytopenia, especially thrombocytopenia that may cause bleeding…
- Conditions
- Splenomegaly; Congestive, Chronic, Panhematopenia; Splenic, Portal Hypertension
- Trial name
- NCT05050994
- Testing
- Microwave ablation
- Where
- Sweden
- Volunteers
- 10 people
- Sponsor
- Karolinska Institutet
Chronic Obstructive Pulmonary Disease (COPD)
Aclidinium/Formoterol Fixed Combination Dose Finding Study
The study seeks to determine the optimal dose of the Aclidinium/Formoterol combination for investigation in Phase III clinical trials
- Trial name
- NCT00626522
- Testing
- Aclidinium bromide and formoterol
- Where
- 9 sites in Australia, Czechia and 2 more
- Volunteers
- 808 people
- Sponsor
- AstraZeneca
Viral Bronchiolitis
Respiratory Physical Therapy on the Cardiac Autonomic Modulation Paediatric Patients
The present study investigated the influence of respiratory affections on the heart rate variability (HRV) of paediatric patients.
- Trial name
- NCT01354561
- Testing
- Respiratory physical therapy
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- University of Sao Paulo
Bronchiolitis
The ROUTT-B (Reduce Over-Utilized Tests and Treatments in Bronchiolitis) Study
Over-testing and over-treatment costs the US healthcare system hundreds of billions of dollars a year, and has measurable negative impacts on patients' physical, emotional, and financial health making it a significant public…
- Trial name
- ROUTT-B (NCT04302207)
- Testing
- De-implementation Strategy for Bronchiolitis
- Where
- 3 sites in United States
- Volunteers
- 20,000 people
- Sponsor
- University of Colorado, Denver
Bronchiolitis Obliterans Syndrome
Imaging and Understanding BOS in Lung Transplantation
This study is a prospective, non-randomized, longitudinal, observational study that will recruit about 5 lung transplant patients per year for 3 years.
- Trial name
- NCT02316392
- Testing
- Hyperpolarized Helium-3 MRI
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Bronchiolitis, Lower Respiratory Tract Infection
Safe, Effective and Cost-Effective Oxygen Saturation Targets for Children and Adolescents With Respiratory Distress: a Randomized Controlled Trial
The goal of this clinical trial is to find out at which lower limit for saturation (amount of oxygen in the blood) we can best give extra oxygen to children that have been admitted for shortness of breath.
- Conditions
- Bronchiolitis, Lower Respiratory Tract Infection, Bronchial Hyperreactivity
- Trial name
- OxyKids (NCT06016244)
- Testing
- Oxygen saturation threshold
- Where
- 9 sites in Netherlands
- Volunteers
- 566 people
- Sponsor
- Spaarne Gasthuis
Chagas' Disease (Chronic) Nos
Oral Fexinidazole Dosing Regimens for the Treatment of Adults With Chronic Indeterminate Chagas Disease
This study focuses on the evaluation of low doses (600 and 1200 mg) and short treatment duration (at 3, 7 and 10 days) of fexinidazole (Fexi) to determine the minimal efficacious and safe dose for the treatment of adult patients…
- Trial name
- FEXI12 (NCT03587766)
- Testing
- Fexinidazole
- Where
- Spain
- Volunteers
- 45 people
- Sponsor
- Drugs for Neglected Diseases
Graft Versus Host Disease, Ophthalmologic Complications
Bandage Lenses in Treating Patients With Ocular Graft-Versus-Host Disease
This phase II clinical trial studies how well bandage lenses work in treating patients with ocular graft versus host disease. Bandage lenses may be helpful in relieving eye symptoms and damage caused by eye graft versus host…
- Trial name
- NCT01616056
- Testing
- graft versus host disease prophylaxis/therapy, questionnaire administration, optical coherence tomography
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Fred Hutchinson Cancer Center
Acute Bronchitis
Acute Bronchitis in Korea:Associated Microorganisms and Clnincal Findings.
The investigators hypothesized that acute bronchitis will be associated with various bacteria and viruses.
- Trial name
- NCT01762865
- Where
- 3 sites in South Korea
- Volunteers
- 300 people
- Sponsor
- Hallym University Medical Center
COPD
A Study to Assess the Safety and Efficacy of Different AD 237 Doses in Adults With COPD
The purpose of this study is to investigate the efficacy, safety and tolerability of AD 237 in patients with chronic obstructive pulmonary disease (COPD).
- Trial name
- NCT00242333
- Testing
- AD 237
- Where
- 33 sites in Bulgaria, Hungary and 2 more
- Volunteers
- 300 people
- Sponsor
- Sosei
Low Back Pain, Chronic
Comparative Effects of Group Based Exercises with and Without Cognitive Functional Therapy on Clinical Outcomes in Patients with Chronic Low Back Pain
1.1Research objective The objective of the study is to find the comparative effects of group based exercises with and without cognitive functional therapy on clinical outcomes in patients with chronic low back? 1.2 Hypothesis…
- Trial name
- NCT06759675
- Testing
- group based exercise with Cognitive functional therapy, Group based exercise
- Volunteers
- 40 people
- Sponsor
- University of Faisalabad
Hematologic Neoplasms
Phase I/II Study to Reduce Post-transplantation Cyclophosphamide Dosing for Older or Unfit Patients Undergoing Bone Marrow Transplantation for Hematologic Malignancies
Background: Certain blood cancers can be treated with blood or bone marrow transplants. Sometimes the donor cells attack the recipient's body, called graft-versus-host disease (GVHD).
- Trial name
- NCT04959175
- Testing
- Mycophenolate Mofetil, Allogeneic HSCT, Fludarabine
- Where
- 2 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Bronchiolitis; Chemical, Reflexology
The Effect of Reflexology in Patients With Viral Bronchiolitis
To test the influence of reflexology on bronchiolitis.
- Trial name
- NCT05799677
- Testing
- Reflexology
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Hillel Yaffe Medical Center
Chronic Graft-Versus-Host Disease, Allogeneic Stem Cell Transplant
Psychosocial Mobile App for Chronic Graft-Versus-Host Disease
The purpose of this research study is to see whether a psychosocial mobile app called Horizons is effective at improving quality of life, symptom burden, psychological distress, and coping in patients living with chronic…
- Trial name
- NCT05690971
- Testing
- App, Usual Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Massachusetts General Hospital
Bronchiolitis
Comparison Between 2l vs 3l in HFNC During the Initial Management of Severe Bronchiolitis in Infants
The purpose of the study is to evaluate prospectively the clinical benefits of 2 different flow with High flow nasal canula (HFNC: 2l/kg/min) versus (HFNC: 2l/kg/min) in the initial management of bronchiolitis in infants.
- Trial name
- TRAMONTANE2 (NCT02824744)
- Testing
- treatment by 2l/min/kg in High Flow Nasal cannula (HFNC), treatment by 3l/min/kg in High Flow Nasal cannula (HFNC)
- Where
- France
- Volunteers
- 300 people
- Sponsor
- University Hospital, Montpellier
Bronchitis, Chronic
AVANTI - Avelox® in Acute Exacerbations of chroNic bronchiTIs
The objective of this global non-interventional study is to evaluate the impact of Acute Exacerbation of Chronic Bronchitis(AECB) on the patient and the community as well as the safety and effect of a treatment with Moxifloxacin…
- Trial name
- NCT00846911
- Testing
- Moxifloxacin (Avelox, BAY12-8039)
- Where
- 8 sites in Albania, Bosnia and Herzegovina and 6 more
- Volunteers
- 2,672 people
- Sponsor
- Bayer
Systemic Juvenile Idiopathic Arthritis (SJIA)
ß-SPECIFIC 4 Patients: Study of Pediatric EffiCacy and Safety wIth FIrst-line Use of Canakinumab
The purpose of this study was to evaluate the efficacy observed with canakinumab dose reduction in a subgroup of patients in the extension study CACZ885G2301E1.
- Trial name
- ß-SPECIFIC 4 (NCT02296424)
- Testing
- ACZ885 150 mg (Canakinumab)
- Where
- 50 sites in United States, Austria and 14 more
- Volunteers
- 182 people
- Sponsor
- Novartis Pharmaceuticals
Pulmonary Diseases, Fever
Pneumocystis Primary Infection in Non-immunosuppressed Infants
To determine the prevalence of P. jirovecii in nasopharyngeal aspirations of neonates and infants hospitalized for symptomatic respiratory infection.
- Trial name
- CAPRI-PC (NCT03740646)
- Where
- France
- Volunteers
- 400 people
- Sponsor
- University Hospital, Brest
Bronchiolitis
Co-infections in Children Hospitalised for Bronchiolitis
Observational cohort study in children hospitalized for acute bronchiolitis. Patients are nursed in cohort isolation. Aim is to investigate the incidence and clinical impact of co-infections in this group.
- Trial name
- NCT01714076
- Testing
- cohort isolation
- Where
- Netherlands
- Volunteers
- 172 people
- Sponsor
- Princess Amalia Children's Clinic
Stroke, Chronic
Effects of Dualsite Anodic tDCS on Lower Limbs Function in Patients After Stroke: Randomized, Double-blind, Placebo-controlled, Crossover Trial
It is currently known that Transcranial Direct Current Stimulation (tDCS) can modulate cortical activity, being considered an important resource in the treatment of sequelae resulting from stroke.
- Trial name
- NCT04850963
- Testing
- Transcranial direct current stimulation (Anodal tDCS) + dual-task training, Transcranial direct current stimulation (tDCS dualsite) + dual-task traning
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Federal University of Paraíba