Clinical trials: Bronchiectasis
Correlation of Inflammatory Markers and Radiological Findings in Stable Bronchiectasis Patients
Correlation of Inflammatory Markers and Radiological Findings in Stable Bronchiectasis Patients With Exacerbation Phenotype
Bronchiectasis, also referred to as non-cystic fibrosis (non-CF) bronchiectasis, is a chronic respiratory disease defined by abnormal and irreversible dilatation of the bronchi (1).
- Trial name
- NCT07495982
- Testing
- Inflammatory Markers and Radiological Findings
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Tobacco Cessation, Asthma COPD
The Effect of Immediate Smoking Cessation Interventions for Smokers With Chronic Airway Diseases
Smoking cessation support is provided by smoking cessation outpatient clinics in our country. Smokers with chronic airway diseases can also apply to these services by making an appointment from quit lines.
- Conditions
- Tobacco Cessation, Asthma COPD, Bronchiectasis Adult
- Trial name
- NCT05764343
- Testing
- Immediate smoking cessation support
- Where
- Turkey (Türkiye)
- Volunteers
- 397 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Bronchiectasis
Autologous Transplantation of Bronchial Basal Cells for Treatment of Bronchiectasis
Bronchiectasis is a disease resulted from progressive destruction of bronchi with no effective drug for its treatment. In this study, we intends to carry out a randomized, single-blinded, controlled pilot clinical trial at 1/2…
- Trial name
- NCT03655808
- Testing
- Bronchial basal cells (BBCs), Bronchoscopic airway clearance treatment （B-ACT）
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Ruijin Hospital
Bronchiectasis Adult
Evaluation of the Effect of Yoga Training on Functional Capacity and Quality of Life in Patients With Bronchiectasis
Evaluation of the Effect of Yoga Training on Functional Capacity and Quality of Life in Patients with Bronchiectasis between the ages of 30-55
- Trial name
- NCT04744220
- Testing
- Yoga Training Program (exercises)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medipol University Hospital
Bronchiectasis Adult
Physiotherapy With Positive Expiratory Pressure (PEP) Bottle in Patients With Bronchiectasis
The aim of this study is to determine whether respiratory physiotherapy using the Positive Expiratory Pressure (PEP) bottle has an effect on respiratory function, measured through spirometry, in patients with a diagnosis of…
- Trial name
- FisioFEV (NCT06820918)
- Testing
- Bottle PEP
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Non-cystic Fibrosis Bronchiectasis, Healthy
The Sputum Colour Chart as a Predictor of Lung Inflammation and Proteolysis in Non-cystic Fibrosis Bronchiectasis
Non-cystic fibrosis bronchiectasis patients (and controls) were recruited for the study. The investigators' aim was to study the relevance of clinical parameters in terms of underlying disease severity, proteolysis and…
- Trial name
- NCT01792440
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Bronchiectasis, Quality of Life
Evaluating the Effects of Traditional Chinese Medicine by N-of-1 Trials
Treatment based on syndrome differentiation is the essence of traditional Chinese Medicine(TCM) and forms the individualized treatment.
- Conditions
- Bronchiectasis, Quality of Life, Traditional Chinese Medicine, Sputum
- Trial name
- NCT03147443
- Testing
- Individualized Decoction, Tested drug minus heat-clearing herbs
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Shanghai University of Traditional Chinese Medicine
Bronchiectasis
Expiratory Muscle Training in Bronchiectasis
Reduced exercise tolerance is commonly reported in patients with bronchiectasis. The purpose of this study is to evaluate the effects of expiratory muscle training (EMT) and sham EMT (control) on exercise capacity, respiratory…
- Trial name
- NCT05408455
- Testing
- EMST150 (Expiratory muscle training)
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Normal Values of Nasal Nitric Oxide in Healthy Adults
Determination of Normal Values of Nasal Nitric Oxide in Adults
Primary ciliary dyskinesia (PCD) is a rare genetic disorder characterized by impaired airway mucociliary clearance leading to recurrent respiratory infections, bronchiectasis and eventually respiratory insufficiency.
- Trial name
- NCT02133547
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Bronchiectasis
Respiratory Mechanics Effects of Flutter Valve in Bronchiectasis Patients
Considering that respiratory physiotherapy lack scientific evidence to support its application in the treatment of several obstructive diseases, this investigation was designed to evaluate the hypothesis that Flutter Valve can…
- Trial name
- NCT00656721
- Testing
- Flutter Valve
- Where
- 2 sites in Brazil
- Volunteers
- 8 people
- Sponsor
- Universidade Federal do Rio de Janeiro
Primary Ciliary Dyskinesia
Evaluating Progression of and Diagnostic Tools for Primary Ciliary Dyskinesia in Children and Adolescents
Mucociliary clearance, in which mucus secretions are cleared from the breathing airways, is the primary defense mechanism for the lungs.
- Trial name
- NCT00450918
- Where
- 5 sites in United States, Canada
- Volunteers
- 150 people
- Sponsor
- University of North Carolina, Chapel Hill
Bronchiectasis
The Prevalence and Impact of Depression and Anxiety Symptoms in Patients With Non-CF Bronchiectasis
Patients with chronic diseases are at great risk of depression and anxiety.It is known that depression and anxiety are one of the most common comorbidities associated with chronic lung diseases such as asthma and chronic…
- Trial name
- NCT01688180
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Asthma, Bronchiectasis
Lung Clearance Index (LCI) in Pediatric Patients With Obstructive Lung Disease
Chronic respiratory diseases (CRDs) affect the airways and other structures of the lungs and thereby lead to ventilation inhomogeneity. The most common CRDs in children are asthma, bronchiectasis and cystic fibrosis (CF).
- Conditions
- Asthma, Bronchiectasis, Cystic Fibrosis
- Trial name
- NCT02950116
- Testing
- Perform three multiple breath nitrogen washout tests (N2-MBW-test)
- Where
- Belgium
- Volunteers
- 27 people
- Sponsor
- Universitair Ziekenhuis Brussel
COPD, Interstitial Pneumonia
Perioperative Risk Factors Related to the Prognosis of Lung Transplantation: A Retrospective Study
This study analyzes patients who underwent lung transplantation at the First Affiliated Hospital of Zhejiang University from 2017 to 2024, focusing on anesthesia's impact on post-op results.
- Conditions
- COPD, Interstitial Pneumonia, Bronchiectasis, Respiratory Failure
- Trial name
- NCT06922916
- Where
- China
- Volunteers
- 250 people
- Sponsor
- Zhejiang University
Chronic Suppurative Lung Disease, Protracted Bacterial Bronchitis
Digital Physiotherapy for Pediatric Chronic Suppurative Lung Diseases
This is a prospective, single-center, two-arm (1:1), assessor-blinded, randomized controlled clinical trial that will be conducted in collaboration with the outpatient clinic of the third Pediatric Pulmonology Unit, "Attikon"…
- Conditions
- Chronic Suppurative Lung Disease, Protracted Bacterial Bronchitis, Primary Ciliary Dyskinesia (PCD), Non Cystic Fibrosis Bronchiectasis
- Trial name
- NCT07376187
- Testing
- Videoconferencing (Vsee platform), Specially designed website (FysΑΩ)
- Where
- Greece
- Volunteers
- 32 people
- Sponsor
- University of Thessaly
Non-Cystic Fibrosis Bronchiectasis
Safety and Efficacy Study of Ciprofloxacin for Inhalation in Patients With Non-Cystic Fibrosis Bronchiectasis "ORBIT-1"
The purpose of this study is to evaluate the safety and efficacy of Ciprofloxacin for Inhalation in the treatment of patients with non-cystic fibrosis (CF) bronchiectasis.
- Trial name
- NCT00889967
- Testing
- Ciprofloxacin for Inhalation
- Where
- 37 sites in United States, Canada and 2 more
- Volunteers
- 95 people
- Sponsor
- Aradigm Corporation
Bronchiectasis, Quality of Life
Evaluation of the Quality of Life of Patients With DBB With the Installation of OPEP
To carry out an assessment of compliance and quality of life in a population (children and adults) with DDB before and after the use of an oscillating PEP.
- Conditions
- Bronchiectasis, Quality of Life, Physiotherapy
- Trial name
- EQOPEP (NCT06820983)
- Testing
- adult questionnary for parents of children aged 8 to 13, Quality of life questionnaire for children aged 8 to 13, Quality of life questionnaire for adolescents aged 14 to 17
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Primary Ciliary Dyskinesia, Kartagener Syndrome
Characterizing the Upper Airway Manifestations in Primary Ciliary Dyskinesia and Primary Immunodeficiencies
Though common, morbidities related to upper airway disease in primary ciliary dyskinesia (PCD) and primary immunodeficiencies (PID) have not been fully characterized.
- Conditions
- Primary Ciliary Dyskinesia, Kartagener Syndrome, Primary Immune Deficiency
- Trial name
- NCT04919018
- Where
- 4 sites in United States, Canada
- Volunteers
- 159 people
- Sponsor
- University of North Carolina, Chapel Hill
Asthma, Chronic Obstructive Pulmonary Disease
Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease
This is a single centre exploratory study that aims to apply hyperpolarized xenon-129 (129Xe) magnetic resonance imaging (MRI) methods and measurements in individual patients with and without lung disease to better understand…
- Conditions
- Asthma, Chronic Obstructive Pulmonary Disease, Bronchiectasis, Emphysema
- Trial name
- NCT03455686
- Testing
- Hyperpolarized 129Xe MRI
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Non-cystic Fibrosis Bronchiectasis (NCFBE)
A Study of HSK31858 in Participants with Non-Cystic Fibrosis Bronchiectasis
This is a phase II, randomised, double-blind, placebo-controlled, multicenter study to assess the efficacy and safety of HSK31858 in non-cystic fibrosis bronchiectasis (NCFBE) participants.
- Trial name
- NCT05601778
- Testing
- HSK31858
- Where
- China
- Volunteers
- 226 people
- Sponsor
- Haisco Pharmaceutical Group Co., Ltd.