Clinical trials: Bronchial Blocker
COPD, Emphysema
Efficacy of Losartan in Preventing Progression of COPD
Evidence in animals shows that losartan can prevent or reverse inflammation and lung damage due to smoking. The goal of this study is to determine whether this drug which is also used to treat hypertension can stabilize or…
- Conditions
- COPD, Emphysema, Chronic Bronchitis, Smoking
- Trial name
- NCT00720226
- Testing
- Losartan
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Johns Hopkins University
Non-small Cell Lung Cancer, Non Small Cell Lung Cancer
Ramucirumab and Atezolizumab After Progression on Any Immune Checkpoint Blocker in NSCLC
Data suggests that combining ramucirumab with immunotherapy in non-small cell lung cancer (NSCLC) patients who have previously received immune checkpoint blockers (ICBs) may be more effective than traditional therapy.
- Conditions
- Non-small Cell Lung Cancer, Non Small Cell Lung Cancer, NSCLC
- Trial name
- RamAtezo-1 (NCT03689855)
- Testing
- Ramucirumab, Atezolizumab, Peripheral blood draw
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Lung Collapse, One-Lung Ventilation
Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung isolation technique and one-lung ventilation (OLV) are the mainstays of thoracic anesthesia. Two principal lung isolation techniques are mainly use by clinicians, the double lumen tubes (DLT) and the bronchial blockers (BB).
- Conditions
- Lung Collapse, One-Lung Ventilation, Thoracic Surgery, Video-Assisted
- Trial name
- PLC-OLV (NCT02919267)
- Testing
- Double lumen tube, Bronchial blocker
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Laval University
Video-assisted Thoracoscopic Surgery, Lung Isolation Device
Lung Collapse With Bronchial Blocker
Lung isolation is frequently used during thoracic surgery. Two techniques are principally used: the double lumen tube (DLT) and the bronchial blocker (BB).
- Conditions
- Video-assisted Thoracoscopic Surgery, Lung Isolation Device, One-lung Ventilation, Double Lumen Endotracheal Tube
- Trial name
- NCT01615263
- Testing
- Lung isolation device
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- Laval University
Respiratory Failure, Respiratory Infection
Avoiding Neuromuscular Blockers to Reduce Complications
The goal of this study to evaluate whether eliminating the use of non-depolarizing neuromuscular blocking agents (NMBA) for maintenance of general anesthesia reduces postoperative pulmonary complications in higher risk patients.
- Conditions
- Respiratory Failure, Respiratory Infection, Aspiration Pneumonia, Pneumonitis
- Trial name
- NCT03962725
- Testing
- Neuromuscular Blocking Agents, Anesthetic Adjuncts
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center