Clinical trials: Breathing, open to volunteers
Asthma (Diagnosis)
Pressurized Meter Dose Inhaler V/S Dry Powder Inhaler
This study compares two commonly used inhalation devices in asthma management. It focuses on evaluating how effectively PMDIs and DPIs deliver the same combination of inhaled corticosteroids and long-acting beta agonists in…
- Trial name
- NCT07372573
- Testing
- Pressurized Metered Dose Inhaler (pMDI), Dry Powder Inhaler
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- University of Health Sciences Lahore
Primary Hypertension
The Effect of Lavender Inhalation on Anxiety, Sleep, and Blood Pressure
This study aims to determine the effects of lavender oil inhalation on anxiety, sleep quality, and blood pressure in patients with primary hypertension. The study is designed as a double-blind randomized controlled trial.
- Trial name
- NCT07192783
- Testing
- Lavender
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Ardahan University
Chronic Kidney Diseases, Insomnia
4-7-8 Breathing for Fatigue and Sleep Management in Hemodialysis
For many hemodialysis patients, fatigue and sleep disturbances are common and debilitating side effects that severely impact daily life and quality of life.
- Conditions
- Chronic Kidney Diseases, Insomnia, 4-7-8 Breathing Technique
- Trial name
- NCT07700693
- Testing
- Breathing technique
- Volunteers
- 80 people
- Sponsor
- Izmir Kavram Vocational School
Obstructive Sleep Apnea (OSA)
Point of Care Ultrasound in Pregnant Women (PoCUS-OB)
Pregnant women with gestational age more than 20 weeks are at risk of developing Obstructive Sleep Apnea (OSA). OSA is a common underdiagnosed comorbid condition in pregnant women associated with adverse maternal and fetal…
- Trial name
- NCT06776237
- Testing
- PoCUS
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery
Video-guided Versus Conventional Right-sided Double-lumen Tube Placement for Thoracoscopic Surgery
Right-sided double-lumen tubes are used for lung isolation during thoracoscopic surgery but can be difficult to position because of right bronchial anatomy.
- Conditions
- Right-sided Double-lumen Tube Positioning, Lung Isolation During Thoracoscopic Surgery, One-lung Ventilation, Lung Cancer
- Trial name
- NCT07849400
- Testing
- Continuous video-guided right-sided double-lumen tube, Conventional right-sided double-lumen tube
- Where
- 3 sites in China
- Volunteers
- 566 people
- Sponsor
- Diansan Su
Healthy Vollunteer, Apnea
Temporal Dynamics of Peripheral SpO₂ During Reoxygenation
Pulse oximeters estimate arterial oxyhaemoglobin saturation (SaO₂) from photoplethysmographic signals recorded at peripheral sites (usually the fingertip), thus measuring the peripheral oxygen saturation (SpO₂).
- Trial name
- PulseOx (NCT07884500)
- Testing
- Voluntary Apnea
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis
MASLD in Type 2 Diabetes in Primary Care - a Follow-up Study
The goal of this observational study is to understand how metabolic dysfunction-associated steatotic liver disease (MASLD) changes over time in individuals with type 2 diabetes who previously participated in the EPSONIP study.
- Conditions
- MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Cirrhosis, Advanced Fibrosis, Sarcopenia
- Trial name
- EPSOMIP2 (NCT07312136)
- Where
- Sweden
- Volunteers
- 317 people
- Sponsor
- Linkoeping University
Chronic Respiratory Failure, Acute Respiratory Failure
Validation Study of the EMILY AI Device in Acute and Chronic Respiratory Failure
Currently, there is no holistic solution for patients with respiratory diseases that includes oxygenation and management of a patient with respiratory disease, combining dynamic and automatic O2 administration and the detection…
- Trial name
- NCT06952816
- Testing
- Emily.AI
- Where
- 2 sites in Spain
- Volunteers
- 20 people
- Sponsor
- Aether Tech S.L.
Obstructive Sleep Apnea
App-Based Optimization of Long-Term CPAP Adherence and Quality of Life
The purpose of this study is to optimize the time of CPAP usage to at least 6 hours a night for 6 nights per week for people who have OSA with the help of a smartphone application called SmartWell24.
- Trial name
- NCT06381115
- Testing
- SleepWell24 Application
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- Mayo Clinic
Mechanical Ventilation Weaning, Spontaneous Breathing Trial
High-Flow Tracheal Oxygen During Spontaneous Breathing Trial
The purpose of this study is to find out whether high-flow tracheal oxygen (HFTO) delivered at flows greater than 60 L/min can increase end-expiratory lung volume (EELV) in intubated patients during a spontaneous breathing trial…
- Conditions
- Mechanical Ventilation Weaning, Spontaneous Breathing Trial, High Flow Oxygen Therapy
- Trial name
- HFTO-SBT (NCT07864415)
- Testing
- T-piece, HFTO 50, washout, HFTO 70, washout, PSV., T-piece, HFTO 70, washout, HFTO 50, washout, PSV.
- Volunteers
- 30 people
- Sponsor
- Argentinian Intensive Care Society
Cardiac Disease
The Effects of Neurophysiological Facilitation Techniques After Coronary Artery Bypass Graft Surgery
The aim of the study is to investigate the effects of neurophysiological facilitation techniques, applied in addition to Phase I cardiac rehabilitation in the early postoperative period after coronary artery bypass graft (CABG)…
- Trial name
- NCT06640699
- Testing
- exercise
- Volunteers
- 36 people
- Sponsor
- Istanbul University - Cerrahpasa
Obstructive Sleep Apnea
Enhancing PAP Adherence Among Spanish-speaking Hispanic Adults With OSA
This study seeks to enhance long-term positive airway pressure (PAP) adherence among Spanish-speaking Hispanic adults, a group with known PAP outcomes disparities.
- Trial name
- NCT05618444
- Testing
- Automated Management (AM)
- Where
- 4 sites in United States
- Volunteers
- 50 people
- Sponsor
- Geisinger Clinic
Asthma (Part 1), COPD
APP-based Medical Device for Education and Training of Inhalation Technique
Primary aim: To investigate if app-based education and training of inhalation technique improves the rate of successful inhalation techniques compared with control group at 6-12 weeks follow-up visit.
- Trial name
- APPETITE (NCT07145632)
- Testing
- App-based education and training of inhalation technique
- Where
- 3 sites in Sweden
- Volunteers
- 80 people
- Sponsor
- Karolinska Institutet
Trauma, Rib Fractures
Percutaneous Cryoablation of Intercostal Nerves for the Treatment of Rib Fractures
The goal of this double blinded randomized control trial is to learn if percutaneous cryoablation of traumatic rib fractures improves outcomes.
- Conditions
- Trauma, Rib Fractures, Chest Wall Disorder, Respiratory Insufficiency
- Trial name
- NCT06533904
- Testing
- Percutaneous Cryoablation of Intercostal Nerves, Multi-modal pain regimen
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Chronic Cough
The Real-world Treatment Satisfaction by Gefapixiant in RCC
Chronic cough has a high global prevalence and it is refractory to such treatments by approximately 20% of patients. Gafapixant is a P2X3 receptor antagonist that has demonstrated the reduction of cough in patients with…
- Trial name
- NCT06542484
- Testing
- Gefapixant Citrate
- Where
- 2 sites in Japan
- Volunteers
- 63 people
- Sponsor
- Nagoya City University
Kyphoplasty, Prone Position
TCI Versus Manual TIVA for Sedation During Prone Kyphoplasty: Effects on Respiration, Recovery, and EEG
This single-center, prospective, observational study compares target-controlled infusion (TCI) versus manually administered total intravenous anesthesia (TIVA) for sedation in patients undergoing kyphoplasty in the prone…
- Conditions
- Kyphoplasty, Prone Position, Target Controlled Infusion of Propofol, End Tidal Carbon Dioxide
- Trial name
- NCT07745348
- Testing
- Target controlled infusion of propofol, non invasive ETCO2 monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital
Chronic Cough
An Observational Study Using Novel Questionnaire to Characterize Cough Phenotypes in Patients With Chronic Cough
Cough has previously been described by the type of cough you have ie such as wet, dry, and chesty, and also by its features such as how often you are coughing its,intensity, and severity, but never has the varying patterns of…
- Trial name
- NCT06376448
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- Hull University Teaching Hospitals NHS Trust
Early Stage Breast Carcinoma, Dyspnea
Inspiratory Muscle Training for Breast Cancer Patients on Chemotherapy
This clinical trial studies whether breathing exercises for the muscles that help with breathing air in, inspiratory muscle training (IMT), works to improve breathing muscle strength, shortness of breath, and physical activity…
- Trial name
- IMACT (NCT07386444)
- Testing
- Inspiratory muscle training
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Concussion, Mild Traumatic Brain Injury
Impact of a Paced Breathing Exercise Intervention on Autonomic Nervous System Function After Pediatric Concussion (Acute Phase)
The goal of this pilot clinical trial is to assess the feasibility of administering a paced breathing exercise intervention program to children and adolescents in the acute period after concussion.
- Trial name
- Breathe - PED (NCT07572734)
- Testing
- Paced breathing exercises
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Respiratory Failure With Hypoxia
Physiological Study of High PEEP in Noninvasive Ventilation
To investigate the physiological effects of high positive end-expiratory pressure (PEEP) during noninvasive ventilation in patients with hypoxemic respiratory failure, and to elucidate the mechanisms underlying high PEEP-induced…
- Trial name
- NCT07503509
- Testing
- high PEEP
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Chongqing Medical University
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