Clinical trials: Breast Lesion
Malignant Neoplasm, Overlapping Lesion of Breast
Breast Lesions Characterization on Contrast Enhanced Ultrasound With Histopathological Correlation
Breast lesions are a common condition, diagnosed by imaging and palpation. In order to reduce the number of biopsies performed to the definitive diagnosis of a breast lesion, an imaging method with a high degree of accuracy is…
- Trial name
- NCT02177045
- Testing
- Sonovue, Bracco
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Breast Diseases
Comparison of Real-time and Shear Wave Elastography
Tissue elasticity is being increasingly used as diagnostic parameter, since at the macroscopic level benign breast lesions tend to be stiffer than normal breast tissue but softer than breast cancers.
- Trial name
- Elasto (NCT03487471)
- Testing
- Real-time elastography, Shear wave elastography
- Where
- Switzerland
- Volunteers
- 98 people
- Sponsor
- University Hospital, Basel, Switzerland
Breast Cancer Female
Breast Lesion in CT Chest
The aims of this study are To evaluate the CT features of incidental breast lesions on chest CT and subsequently suggest useful criteria for referral to a specialized breast unit.
- Trial name
- NCT06196216
- Testing
- MSCT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Breast Lesions
A Registry Study Evaluating Outcomes in Breast Biopsy With the Intact™ Breast Lesion Excision System (BLES)
The purpose of this registry study is to collect use and clinical outcomes data following breast lesion excision or sampling with the Intact BLES.
- Trial name
- NCT03520127
- Testing
- Intact Breast Lesion Excision System (BLES)
- Where
- 7 sites in United States
- Volunteers
- 176 people
- Sponsor
- Medtronic Surgical Technologies
Breast Lesion
Breast MRI Spectroscopy, Department of Defense (DOD)
The purpose of this new imaging method is to provide physicians with additional information not available with standard imaging methods. This includes information about the make up of different breast diseases.
- Trial name
- NCT00582569
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Diseases
To Evaluate the Efficacy and Safety of LuminoMark Injection in Patients With Nonpalpable Breast Lesions(Phase 3)
This study is a multicenter, Randomized, Open-label, Parallel, Phase 3 Clinical Trial in 8 weeks for screening, once Investigational product injection, Follow up visit.
- Trial name
- NCT04606329
- Testing
- LuminoMark inj.(Conc. for fluorescence), Charcotrace Inj.
- Where
- South Korea
- Volunteers
- 109 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Breast Cancer, Endocrine Disruptors
Confirmation of the Link Between Endocrine Disruptors Exposure and Breast Cancer and Identification of Biological Response Biomarkers
A wide variety of chemicals are constantly being introduced in our environment. The toxicological consequences related to the exposure to these compounds and their impact on public health ar of growing concern.
- Conditions
- Breast Cancer, Endocrine Disruptors, Metabolomics, Breast Lesions
- Trial name
- EXPOSAL (NCT07411651)
- Testing
- Collection of biological and clinical data
- Where
- France
- Volunteers
- 42 people
- Sponsor
- Poitiers University Hospital
Breast Neoplasms
Magnetic Occult Lesion Localization and Imaging (MOLLI)
The proposed trial is a non-randomized, single-arm study examining the technical feasibility and safety of magnetic occult lesion localization and imaging (MOLLI) for Breast Conserving Surgery (BCS), in patients with non-palpable…
- Trial name
- MOLLI (NCT03660137)
- Testing
- MOLLI Localization
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Breast Cancer
ROLL vs WGLL for Non-palpable Breast Lesions
Here were present a controlled clinical trial comparing wire-guided lesion localization (WGLL)and radioguided occult lesion localization (ROLL) in patients treated for nonpalpable breast lesions at the Instituto Nacional de…
- Trial name
- ROLLvsWGLL (NCT02869230)
- Testing
- ROLL, wire-guided lesion localization
- Volunteers
- 129 people
- Sponsor
- Instituto Nacional de Cancerologia, Columbia
Non-palpable Breast Lesions
Evaluation of RFID Localization System for Marking and Retrieving Breast Lesions
The goal of this investigation is to obtain clinical data to show the Health Beacons Radiofrequency Identification (RFID) Localization System is safe and performs as intended as a localization device for marking and retrieving a…
- Trial name
- NCT01574664
- Testing
- RFID Tag (Health Beacon)
- Where
- 3 sites in United States
- Sponsor
- Health Beacons
Neoplasm of Breast
Ultrasound Guided Percutaneous Microwave Ablation for Breast Lesions
The investigators will perform this study to prospectively analyse the clinical outcome after percutaneous microwave ablation(MWA) of benign and malignant breast lesion under ultrasound (US) guidance.
- Trial name
- NCT02860104
- Testing
- microwave ablation
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Chinese PLA General Hospital
Lung Cancer, Breast Cancer
Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis
The purpose of this study is to to compare lung function data generated by applying High Fidelity Functional Lung Imaging (HFFLI) software to 4D CT, cone beam CT, and fluoroscopic images of the lungs breathing to determine…
- Conditions
- Lung Cancer, Breast Cancer, Mediastinum Lesion, Radiation Pneumonitis
- Trial name
- HFFLI (NCT02735746)
- Testing
- 4D Computed Tomography (CT), Cone Beam CT, Low-dose Cinefluorography
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Cedars-Sinai Medical Center
Breast Cancer, Breast Benign
Development Of A Blood Test To Improve The Performance Of Breast Cancer Screening
The purpose of this study is to collect blood and tissue to help develop tests that might be able to detect cancer earlier. The investigator will be collecting these samples and reviewing test results from participants who have…
- Trial name
- NCT03372902
- Testing
- Breast MRI, Breast Mammogram, Blood draw
- Where
- 7 sites in United States
- Volunteers
- 628 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Breast Cancer With Bone Metastasis
Safety/Efficacy of Intravenous Zoledronic Acid When Added to Standard Therapies in Patients With Breast Cancer and Metastatic Bone Lesions
Zoledronic acid selectively binds to bone and protects it from being metastasized by tumor cells. This study evaluates the safety and efficacy of zoledronic acid when added to standard therapies in breast cancer patients with…
- Trial name
- NCT00372710
- Testing
- Zoledronic acid
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Novartis
Breast Neoplasms
The MONET - Study: MR Mammography of Nonpalpable Breast Tumors
The purpose of this study is to determine whether performing MRI of the breast will improve breast cancer management by reducing the number of biopsies and in case of malignancy allowing one-stage surgical excision of the tumor.
- Trial name
- MONET (NCT00302120)
- Testing
- Contrast-enhanced MR mammography
- Where
- 3 sites in Netherlands
- Volunteers
- 440 people
- Sponsor
- UMC Utrecht
Breast Neoplasms
Evaluation of Virtual Touch Tissue Imaging Quantification (VTIQ - 2D-SWE) in the Assessment of BI-RADS® 3 and 4 Lesions
The primary aim of this study is to evaluate if VTIQ in addition to BI-RADS® categorization can improve the diagnostic accuracy with respect to detection of malignancies, in particular for BI-RADS® categories 3 and 4a.
- Trial name
- NCT02638935
- Testing
- Ultrasound- Virtual Touch Tissue Imaging Quantification
- Where
- 11 sites in United States, France and 4 more
- Volunteers
- 1,304 people
- Sponsor
- Heidelberg University
Breast Disease, Phyllodes Breast Tumor
Cryotherapy in Breast B3 Lesions
To determine the feasibility of cryotherapy for B3 fibroepithelial lesions
- Trial name
- NCT04571307
- Testing
- cryotherapy
- Where
- Singapore
- Volunteers
- 12 people
- Sponsor
- KK Women's and Children's Hospital
Breast Cancer Patient
Evaluation in the Treatment of Neuropathic Pain Post Breast Surgery
Breast cancer is the most common cancer in women in Europe. Therefore, breast cancer has become a chronic disease and patients need to learn to live with it as well as with the adverse effects related to the disease itself or to…
- Trial name
- CAPTRANE (NCT03794388)
- Testing
- Capsaicin, Pregabalin
- Where
- 11 sites in France
- Volunteers
- 140 people
- Sponsor
- Institut Cancerologie de l'Ouest
Breast Cancer
Digital Breast Tomosynthesis Guided Tomographic Optical Breast Imaging (TOBI)
Screening for breast cancer improves early detection of aggressive cancers and has been shown to reduce breast cancer related mortality.
- Trial name
- NCT02033486
- Testing
- TOBI + DBT
- Where
- United States
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Invasive Breast Cancer
Evaluation of an Integrated Imaging System For In Vivo Detection of Fluorescently Labeled Lesions
This is a pilot study to test and characterize the ability of the Smart Goggles system to detect fluorescently labeled sentinel lymph nodes (SLNs).
- Trial name
- NCT02802553
- Testing
- Smart Goggle, Cardio-Green, SPY Elite Imaging system
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Case Comprehensive Cancer Center