Clinical trials: Breast Hypertrophy
Healthy, Macromastia
NPWT Reduction Mammaplasty
In this prospective, randomized, split-body control trial, we aim to compare complications, patient-reported outcomes, and cost differentials following reduction mammaplasty with prophylactic closed incision negative pressure…
- Conditions
- Healthy, Macromastia, Negative Pressure Therapy, Mammaplasty
- Trial name
- NCT06725459
- Testing
- Prophylactic ciNPWT, Standard Adhesive Dressing
- Where
- United States
- Volunteers
- 92 people
- Sponsor
- Medstar Health Research Institute
Macromastia (Symptomatic)
Use of the PEAK PlasmaBlade 4.0 in Bilateral Breast Reduction
The objective of this clinical study is to evaluate the operative performance of the PEAK PlasmaBlade® 4.0 during bilateral breast reduction; to monitor and record post-operative pain, adverse events and skin scarring following…
- Trial name
- NCT01404351
- Testing
- PEAK PlasmaBlade, Scalpel and Traditional Electrosurgery
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Medtronic Surgical Technologies
Breast Hypertrophy
ESPB Versus Intravenous Lidocaine for Pain After Mastopexy
Elective breast reduction surgery is associated with moderate-to-severe postoperative pain and a risk of developing chronic postsurgical pain.
- Trial name
- NCT07687069
- Testing
- Ultrasound - guided Erector Spine Plane Block (ESPB), Intraoperative intravenous lidocaine infusion
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Centre of Postgraduate Medical Education
Macromastia, Signs and Symptoms
Reduction Mammaplasty and Improved Quality of Life
The data gathered here will be used to evaluate the efficacy and safety of the mammary reduction in patients with macromastia.
- Conditions
- Macromastia, Signs and Symptoms, Quality of Life
- Trial name
- MammaRed (NCT02769559)
- Testing
- Reduction mammaplasty
- Where
- Slovakia
- Volunteers
- 52 people
- Sponsor
- University Hospital Bratislava
Scar, Surgical Scar
Pilot Study of a Novel 532nm KTP Laser for the Treatment of Fresh Surgical Scars
The purpose of this study is to evaluate the safety and efficacy of the 532nm potassium titanyl phosphate (KTP) laser in comparison with the 595nm pulsed-dye laser (PDL) for the treatment of fresh surgical scars.
- Conditions
- Scar, Surgical Scar, Cicatrix, Cicatrix, Hypertrophic
- Trial name
- NCT01789346
- Testing
- 532nm KTP, 595nm PDL
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Cutera Inc.
Mammary Gland Hyperplasia
Indications for Breast Reduction in the Public Health Care System
The overall purpose of the project is to create a scientific basis for which patients should be offered breast reduction in the public sector.
- Trial name
- NCT04889469
- Testing
- Breast reduction
- Where
- Sweden
- Volunteers
- 2,000 people
- Sponsor
- Vastra Gotaland Region
Breastfeeding, Hypertrophic Cardiomyopathy
Mavacamten Pregnancy Surveillance Program
The purpose of this observational pregnancy safety study is to assess maternal, fetal, and infant outcomes after exposure to mavacamten at any time during pregnancy and/or breastfeeding.
- Conditions
- Breastfeeding, Hypertrophic Cardiomyopathy, Pregnancy Related
- Trial name
- NCT05939700
- Testing
- Mavacamten
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Bristol-Myers Squibb
Sexual Function, Depression
Sexuality After Reduction Mammaplasty
The aim of this study is to determine the impact of reduction mammaplasty on sexuality and depression predictors in women with macromastia.
- Trial name
- NCT01020422
- Testing
- Reduction mammaplasty
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Daniela Francescato Veiga
Breast Hypertrophy
Reduction of Breast Enlargement Using the Da Vinci Xi Robot
Breast enlargement reductions are frequent interventions. One of the main issue associated with this surgery remains the ransom scar, wide at the periareolar level, vertical at the subareolar level and in the submammary groove.
- Trial name
- R-HTM-R (NCT04597515)
- Testing
- Robot Breast reduction surgery
- Where
- France
- Volunteers
- 5 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Breast Hypertrophy
Comparison of Superomedial and Inferior Pedicle Techniques in Mammaplasty
The aim of this study is to evaluate Superomedial pedicle and Inferior pedicle techniques in breast reduction for Egyptian females and compare between both pedicles regarding cosmetic outcomes, possible complications, patient…
- Trial name
- NCT03669679
- Testing
- Breast reduction
- Volunteers
- 19 people
- Sponsor
- Assiut University
Reduction of Hypertrophic Skin Scarring
Safety and Efficacy Study of PF-06473871 to Reduce Hypertrophic Scars From Recurring Post-Revision Surgery
The study will compare how well PF-06473871 works versus placebo in reducing skin scarring after scar revision surgery of existing breast scars. The study will also evaluate the safety of PF-06473871 in healthy adult subjects.
- Trial name
- NCT01730339
- Testing
- PF-06473871
- Where
- 40 sites in United States, Germany and 2 more
- Volunteers
- 103 people
- Sponsor
- Pfizer
Breast Augmentation
Improved Breast Enlargement Using the Subject's Own Fat Tissue
The goal of this clinical study is to learn if the Medical Device Under Investigation (simply "the device") is safe to use in human adults undergoing breast augmentation surgery.
- Trial name
- SWIFT (NCT07869641)
- Testing
- An injectable, biodegradable hydrogel, in reconstitution medium, Reconstitution medium
- Where
- 2 sites in Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- 4Tissue
Gynecomastia, Male Breast Enlargement
UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia)
Male volunteers who suffer from Pseudogynecomastia and seek noninvasive breast fat reduction will be enrolled into two arms to receive three biweekly UltraShape treatments.
- Trial name
- NCT02711605
- Testing
- UltraShape focused ultrasound device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Syneron Medical
Breast Hypertrophy
Vertical Scar Versus Inferior Pedicle Reduction Mammoplasty
Main research question: Is vertical scar reduction mammoplasty superior when compared to inferior pedicle reduction mammoplasty in terms of patient quality of life and cost-effectiveness? Why is this research important?: There is…
- Trial name
- NCT00149344
- Testing
- Vertical scar versus inferior pedicle reduction mammoplasty
- Where
- Canada
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- McMaster University
Postoperative Pain, Breast Hypertrophy
Bilateral Ultrasound-Guided Erector Spinae Plane Block For Postoperative Analgesia in Breast Reduction Surgery
Erector spinae plane (ESP) block is a novel block developed by Forero to treat severe neuropathic pain and was firstly reported in 2016.
- Trial name
- NCT03621345
- Testing
- Erector spinae plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Cukurova University
Augmentation, Augmentation Revision
Spectra Breast Implant Study
The purpose of this study is to demonstrate safety and effectiveness of Mentor's Spectra/Becker 80 Adjustable Breast Implants in women who are undergoing primary or revision breast augmentation.
- Conditions
- Augmentation, Augmentation Revision, General Breast Enlargement, Post-lactational Involution
- Trial name
- NCT00981266
- Testing
- Mentor Spectra/Becker 80 Breast Implant
- Where
- United States
- Sponsor
- Mentor Worldwide, LLC
Macromastia
An Observational Study Exploring the Esthetic Outcomes of Breast Reduction Surgery and /or Mastopexy
The purpose of the study is to collect data regarding the aesthetic outcomes of patients who had breast reduction surgery and /or mastopexy in terms such as scaring, patient satisfaction, breast ptosis assessment including taking…
- Trial name
- NCT02016677
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Orbix Medical Ltd.
Scar, Hypertrophic Scar
The Efficacy and Molecular Mechanism of Botulinum Toxin in the Reduction of Breast Reduction Mammoplasty Scar Formation
1. Test the ability of botulinum toxin type A, when injected into the surgical incision at the time of surgery, to decrease postoperative scar scores compared to control (normal saline) in a double-blinded randomized control…
- Conditions
- Scar, Hypertrophic Scar, Mammary Disorder
- Trial name
- NCT03887377
- Testing
- Botulinum Toxins, Normal saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Macromastia (Symptomatic)
Pectoral Block in Breast Reduction for Pain Control
A reduction mammoplasty is a commonly performed procedure for patients with symptomatic macromastia. The procedure involves removing breast parenchyma for an overall reduction in breast size and to alleviate patient symptoms…
- Trial name
- NCT07527039
- Testing
- Pectoral II Nerve Block, Post Operative Pain Relievers
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Carilion Clinic
Macromastia, Post-operative Pain
Subpectoral Bupivacaine for Pain Management in Adolescent Reduction Mammaplasty
The main question this randomized control trial aims to answer is: Is the use of intraoperative subpectoral bupivacaine associated with decreased post-operative pain in adolescent patients who undergo bilateral reduction…
- Trial name
- NCT05898087
- Testing
- Marcaine 0.25 % Injectable Solution, Saline
- Where
- 2 sites in United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Connecticut Children's Medical Center