Clinical trials: Breast Cancer Surgery
Analgesia, Cancer, Breast
Serratus Plane Block Versus Serratus Plane Block Plus Parasternal Block Combination for Breast Surgery
Mastectomy is a technique often used in breast cancer surgery. Patients experience moderate to severe pain postoperatively after this procedure.
- Trial name
- NCT05911373
- Testing
- group serratus plan block, group serratus and parasternal plan block
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Ataturk University
Breast Cancer, Anxiety
AR Health Education Video for Postoperative Breast Cancer Patients
Breast cancer surgery patients may experience anxiety and depression before and after surgery. Health education can help patients understand the surgical process and postoperative care, but traditional education may not always be…
- Conditions
- Breast Cancer, Anxiety, Depression
- Trial name
- AR-BCS (NCT07604389)
- Testing
- Augmented Reality Health Education Video, Routine Health Education
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Tungs' Taichung Metroharbour Hospital
Breast Cancer, Frailty
VR for Surgical Prehabilitation and Rehabilitation
This randomized controlled trial aims to determine feasibility and acceptability of of VR-physical therapy modules for surgical patients undergoing breast or axilla surgery in order to prepare for and recover from surgery.
- Conditions
- Breast Cancer, Frailty, Surgery
- Trial name
- VR-PREP (NCT06334380)
- Testing
- Virtual Reality Modules Only, Virtual Reality Modules + Live Physical Therapist Support
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Breast Tumors, Wound Healing
HealiAid Collagen Wound Dressing in Patients Undergoing Breast Tumor Surgery
The goal of this clinical trial is to evaluate the safety of the collagen wound dressing (HealiAid) in breast tumor patients with surgical treatment. The main questions it aims to answer are: 1.
- Conditions
- Breast Tumors, Wound Healing, Collagen Wound Dressing
- Trial name
- NCT07209020
- Testing
- HealiAid Collagen Wound Dressing
- Where
- 3 sites in Taiwan
- Volunteers
- 60 people
- Sponsor
- Maxigen Biotech Inc.
Axillary Web Syndrome, Breast Cancer
Axillary Web Syndrome After Breast Cancer Surgery: Incidence, Risk Factors, and Functional Outcomes
Axillary web syndrome (AWS), sometimes called "cording," is a condition that can develop after breast cancer surgery in which the lymph nodes under the arm are removed or sampled.
- Conditions
- Axillary Web Syndrome, Breast Cancer, Breast Cancer Lymphedema, Postoperative Complications
- Trial name
- NCT07780240
- Testing
- Axillary surgery (sentinel lymph node biopsy or axillary lymph node dissection)
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Antalya City Hospital
Breast Conserving Surgery
Evaluation of a New Technique to Fill the Defect Generated After Conservative Surgery in Breast Cancer
The placement of a small silicone prosthesis in the partial defects generated by conservative breast cancer surgery improves the aesthetic result, compared to the usual surgical technique, in a safe and reproducible way and…
- Trial name
- PROSILMA (NCT04092842)
- Testing
- Silicone prosthesis, Usual practice
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Female Breast Cancer
Ultra-hypofractionated Radiotherapy in Breast Cancer Patients
The present multicenter, retrospective and prospective observational study, aims to evaluate an ultra-hypofractionated whole breast irradiation schedule (WBI, 26 Gy in 5 fractions), in order to confirm literature data (FAST-F…
- Trial name
- NCT05586256
- Testing
- ultra-hypofractionated whole breast irradiation
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- University Of Perugia
Breast Cancer, Lipid Cell; Tumor
Lipidomic Characterization in Non-metastatic Breast Cancer Women Undergoing Surgery: a Pilot Study.
The goal of this clinical trial is to learn about breast cancer lipodome signature in patients waiting for surgery with different Body Mass Index.
- Conditions
- Breast Cancer, Lipid Cell; Tumor, Nutrition Related Cancer, Body Weight
- Trial name
- BreCaLip (NCT06026631)
- Testing
- Lipidomic analysis for breast cancer patients
- Where
- Italy
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Breast Neoplasm, Lesion
Radiofrequency Identification Technology in Locating Non-palpable Breast Lesions in Patients Undergoing Surgery
This pilot clinical trial studies radiofrequency technology in locating non-palpable breast lesions in patients undergoing surgery.
- Trial name
- NCT03202472
- Testing
- Implanted Medical Device, Mammography, Questionnaire Administration
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer, Lymphocele
Efficacy Study of Ifabond in Breast Cancer Surgery
A randomized prospective simple-blind interventional study evaluating the efficacy of the synthetic adhesive solution "Ifabond", in patients undergoing breast cancer surgery.
- Trial name
- Ifabond (NCT01742975)
- Testing
- IFABOND (TM)
- Where
- 2 sites in France
- Volunteers
- 104 people
- Sponsor
- Hôpital Européen Marseille
Breast Cancer (Early Breast Cancer)
A Study on the Treatment of Early Small Breast Cancer With Ultrasound-guided Vacuum-assisted Excision Combined With Surgery
The aim of this clinical trial is to assess the feasibility and safety of ultrasound-guided vacuum-assisted excision (VAE) in the treatment of early breast cancer with Tis (carcinoma in situ) or T1 (maximum tumor diameter ≤2cm)…
- Trial name
- NCT07071402
- Testing
- Ultrasound-guided vacuum-assisted excision combined with surgical treatment
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Breast Cancer
A Prospective, Phase II Trial Using ctDNA to Initiate Post-operation Boost Therapy After Adjuvant Chemotherapy in TNBC
Circulating tumor DNA (ctDNA) has been demonstrated to be an effective prognostic marker in breast cancer. Various studies have shown that early TNBC breast cancer patients with positive ctDNA have high risk of cancer recurrence…
- Trial name
- Artemis (NCT04803539)
- Testing
- capecitabine, capecitabine + camrelizumab + apatinib
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Pain, Postoperative, Breast Cancer
Using Bupivacaine Locally in the Mastectomy Drains to Control Postoperative Pain
in this study we are investigating the role of instillation of Bupivacaine through surgical drains at the end of mastectomy surgeries in controlling post operative pain and decreasing their pain killers requirement in the early…
- Trial name
- NCT03799757
- Testing
- 40ml of 0.25% bupivacaine, 40ml of 0.9% normal saline
- Where
- Egypt
- Volunteers
- 168 people
- Sponsor
- Alexandria University
Breast Cancer
Docetaxel and Carboplatin With or Without Trastuzumab Before Surgery in Treating Women With Locally Advanced Breast Cancer
RATIONALE: Drugs used in chemotherapy, such as docetaxel and carboplatin, use different ways to stop tumor cells from dividing so they stop growing or die.
- Trial name
- NCT00068341
- Testing
- trastuzumab, carboplatin, docetaxel
- Where
- 4 sites in United States
- Volunteers
- 74 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Breast Cancer, Surgery
Study to Assess the Impact of Personalized Coaching on the Time Period and Quality of Return to Work After Breast Cancer
Evaluate the impact of coaching sessions on the return to work rate (number of patients returning at work / total number of patients per arm) 6 months after inclusion in the study for breast cancer in professionnally active…
- Trial name
- OPTICOACH (NCT04469205)
- Testing
- Coaching sessions
- Where
- 2 sites in France
- Volunteers
- 69 people
- Sponsor
- Institut Curie
Breast Cancer
Docetaxel Followed by Surgery in Treating Women With Stage II or Stage III Breast Cancer
RATIONALE: Dose-dense scheduling with (peg)filgrastim support may improve the clinical and pathologic complete response rate (pCR) and safety profile of single agent neoadjuvant docetaxel therapy.
- Trial name
- NCT00343512
- Testing
- docetaxel, protein expression analysis, laboratory biomarker analysis
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Breast Neoplasm Female, Analgesics
U/S Guided Rhomboid Intercostal Block Combined With Sub-Serratus Plane Block vs Type 2 Pectoral Nerve Block
The aim of this study is to compare between U/S Guided Rhomboid Intercostal Block Combined with Sub-Serratus Plane Block vs type 2 Pectoral Nerve Block in Analgesia for Breast Cancer Surgery by measuring intraoperative…
- Trial name
- NCT06274814
- Testing
- U/S guided Type 2 Pectoral Nerve Block, U/S guided RIB combined with the sub-serratus plane block (RISS)
- Where
- Egypt
- Volunteers
- 69 people
- Sponsor
- National Cancer Institute, Egypt
Breast Cancer
Dragon Boat Race Versus Family Unsupervised Training to Improve the Physical Function and Quality of Life in Breast Cancer Patients
Investigators plans to conduct a randomized, open, single center clinical study of Dragon Boat Race versus family unsupervised training to improve the physical function and quality of life in breast cancer patients to compare the…
- Trial name
- NCT07162298
- Testing
- Dragon Boat Training, Home-based Unsupervised Training
- Where
- China
- Volunteers
- 72 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
DCIS
Preoperative Palbociclib in Patients With DCIS of the Breast That Are Candidates for Surgery
This is a feasibility study which will evaluate the effects of pre-operative treatment of DCIS of the breast with palbociclib. Patients with biopsy-proven DCIS are eligible for the study.
- Trial name
- WI223281 (NCT03535506)
- Testing
- Palbociclib
- Where
- 2 sites in United States
- Volunteers
- 17 people
- Sponsor
- Georgetown University
Breast Neoplasms, Treatment
Classified Treatment Strategy for De-novo Metastatic Breast Cancer After Systemic Adjuvant Therapy
For patients with de novo stage IV breast cancer, the current debate is whether local surgery can improve the survival of patients.
- Conditions
- Breast Neoplasms, Treatment, Metastatic Breast Cancer, Survival
- Trial name
- CS (NCT05285332)
- Testing
- surgical treatment 1, surgical treatment 2, Systemic therapy
- Volunteers
- 362 people
- Sponsor
- Changhai Hospital